67 research outputs found
The deformation and elastic anisotropy of a new gyroid-based honeycomb made by laser sintering
© 2020 The Author(s) The stiffness, anisotropy and structural deformation of three gyroid-based lattices was investigated, with particular focus on a newly proposed honeycomb gyroid. This honeycomb is based on a modified triply periodic minimal surface (TPMS) equation with reduced periodicity. Using the numerical homogenisation method, the anisotropy of the gyroid lattice types was found to differ greatly, as was the dependence of this anisotropy on the volume fraction. From compression testing of laser sintered polyamide PA2200 specimens, the honeycomb gyroid was found to possess extremely high anisotropy, with Emax*/Emin*, the ratio of the highest to the lowest direction-dependent modulus, ∼250 at low volume fraction. The stiffness and anisotropy of the honeycomb gyroid are compared to equivalent results from the square honeycomb, the closest analogue in the set of conventional honeycomb types. The honeycomb gyroid lattice exhibited novel deformation and post-yield stiffening under in-plane loading; it underwent reorientation into a second, stiffer geometry following plastic bending and contact of its cell walls. The unique deformation behaviour and extremely high anisotropy of the honeycomb gyroid provide strong motivation for further investigations into this new family of reduced periodicity TPMS-based honeycombs
Creep characterisation of Inconel 718 lattice metamaterials manufactured by laser powder bed fusion
Lattice metamaterials manufactured by laser powder bed fusion (LPBF) are limited by their performance for critical applications. LPBF materials have microstructural or macroscale anomalies, such as suboptimal grain size, morphology, and lack of fusion. This results in LPBF metamaterials performance degradation for various mechanical properties, such as creep, which has seldom been researched. To understand the creep behavior of LPBF Inconel 718, body-centered cubic metamaterials are fabricated for creep test at 650 °C. Kachanov's damage modeling is used to predict the creep performance of the metamaterials under different loading conditions. Microstructural characterization is performed with scanning electron microscopy to identify critical microstructure defects affecting the failure mechanisms and creep behaviors of the metamaterials. It is shown in the results that the loading conditions affect the fracture process of the metamaterials owing to different failure mechanisms. In the simulation and test results, the logarithmic decline in creep life is shown when loading increases; also, logarithmic increase in the creep life is shown when relative density increases
Three-dimensional resonating metamaterials for low-frequency vibration attenuation
Recent advances in additive manufacturing have enabled fabrication of phononic crystals and metamaterials which exhibit spectral gaps, or stopbands, in which the propagation of elastic waves is prohibited by Bragg scattering or local resonance effects. Due to the high level of design freedom available to additive manufacturing, the propagation properties of the elastic waves in metamaterials are tunable through design of the periodic cell. In this paper, we outline a new design approach for metamaterials incorporating internal resonators, and provide numerical and experimental evidence that the stopband exists over the irreducible Brillouin zone of the unit cell of the metamaterial (i.e. is a three-dimensional stopband). The targeted stopband covers a much lower frequency range than what can be realised through Bragg scattering alone. Metamaterials have the ability to provide (a) lower frequency stopbands than Bragg-type phononic crystals within the same design volume, and/or (b) comparable stopband frequencies with reduced unit cell dimensions. We also demonstrate that the stopband frequency range of the metamaterial can be tuned through modification of the metamaterial design. Applications for such metamaterials include aerospace and transport components, as well as precision engineering components such as vibration-suppressing platforms, supports for rotary components, machine tool mounts and metrology frames
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The BCC Unit Cell for Latticed SLM Parts; Mechanical Properties as a Function of Cell Size
The existing framework describing the mechanical properties of lattices places strong
emphasis on one important property, the relative density of the repeating cells. In
this work, we explore the effects of cell size, attempting to construct more complete
models for the performance of lattices. This was achieved by examining the elastic
modulus and ultimate tensile strength of latticed parts with a range of unit cell sizes
and fixed density. The parts were produced by selective laser melting (SLM). The
examined cell type was body-centred-cubic (BCC), a cell of high relevance for SLM
because of its self-supporting structure. We obtained power law relationships for the
mechanical properties of our latticed specimens as a function of cell size, which are
similar in form to the existing laws for the density dependence. These can be used
to predict the properties of latticed column structures comprised of BCC cells, and
may be easily amended for other situations. In addition, we propose a novel way to
analyse the elastic modulus data, which may lead to more general models, applicable
to parts of varying size. Lastly, our general methodology may be of use in future
studies which explore the other parameters that determine lattice performance; the
choice of cell type, the global shape of the lattice structure and the type of stress.Mechanical Engineerin
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Fatigue Performance Enhancement of Selectively Laser Melted Aluminum Alloy by Heat Treatment
We measured the stress-strain behaviour and fatigue performance of the aluminium
alloy Al-Si10-Mg manufactured by selective laser melting (SLM). This process, specifically the rapid cooling of the metal from its molten state, results in a fine microstructure, generally providing high hardness but poor ductility. We used a heat treatment
to alter the microstructure of the material from its as-built state. This significantly
improved the ductility and fatigue performance. The elongation at break for the heat
treated material was nearly three times greater than that observed for the as-built
material, and the fatigue strength at 106
cycles was around 1.6 times as high. Combined with the design freedoms of additive manufacture, this development increases
the suitability of lightweight SLM parts for use in the aerospace and automotive
sectors, where good fatigue performance is essential.Mechanical Engineerin
A mechanical property evaluation of graded density Al-Si10-Mg lattice structures manufactured by selective laser melting
Metal components with applications across a range of industrial sectors can be manufactured by selective laser melting (SLM). A particular strength of SLM is its ability to manufacture components incorporating periodic lattice structures not realisable by conventional manufacturing processes. This enables the production of advanced, functionally graded, components. However, for these designs to be successful, the relationships between lattice geometry and performance must be established. We do so here by examining the mechanical behaviour of uniform and graded density SLM Al-Si10-Mg lattices under quasistatic loading. As-built lattices underwent brittle collapse and non-ideal deformation behaviour. The application of a microstructure-altering thermal treatment drastically improved their behaviour and their capability for energy absorption. Heat-treated graded lattices exhibited progressive layer collapse and incremental strengthening. Graded and uniform structures absorbed almost the same amount of energy prior to densification, 6.3±0.26.3±0.2 MJ/m3 and 5.7±0.25.7±0.2 MJ/m3, respectively, but densification occurred at around 7% lower strain for the graded structures. Several characteristic properties of SLM aluminium lattices, including their effective elastic modulus and Gibson-Ashby coefficients, C1 and α, were determined; these can form the basis of new design methodologies for superior components in the future
On the development of twinning-induced plasticity in additively manufactured 316L stainless steel
A report on twinning-induced plasticity in 316L stainless steel manufactured by metal additive manufacturing (AM) is presented. A tapered tensile test geometry was used which enabled the investigation of twin formation over a range of strain levels in a single specimen. Hardness and twinning concentration were observed to increase with strain up to peak values of 380 ± 10 HV and 28 ± 4%, respectively. Furthermore, twin formation was found to be regulated by grain size and crystal texture. This methodology can be applied to new AM materials development and will inform the design of energy-absorbing structures that maximise the benefits of AM design and strain-hardenable materials
FLatt Pack: A research-focussed lattice design program
Lattice structures are an important aspect of design for additive manufacturing (DfAM). They enable significant component light-weighting and the tailoring of a wide range of physical responses; mechanical, thermal, acoustic, etc. In turn, lattice design relies on fundamental research to uncover useful structure-property relationships, such as the influence of cell geometry and volume fraction. A number of commercial computer-aided-design (CAD) programs exist that offer lattice generation, but these tend to prioritise product design. This paper describes the FLatt Pack program (or Functional Lattice Package), which was created to address the paucity of research-focussed lattice design software. It possesses a number of features with this in mind, including; (i) it is free to use for research, (ii) it is standalone software with minimal, and also free, dependencies, and (iii) it undergoes frequent and rapid development based on state of the art lattice information and modelling methods. FLatt Pack includes twenty-three lattice cell types covering a broad range of pore connectivity, structural anisotropy, and surface area; a clear GUI presenting the lattice design stages in a sequential manner; and the option to export designs in appropriate formats for AM and finite element (FE) simulation. The program also features conformal lattice generation in arbitrary shapes, arbitrary volume fraction grading, and resource-efficient computation through an adaptive spatial resolution based on the user's design choices. The most recent version of FLatt Pack is freely available at: www.github.com/ian27ax/FLatt_Pack_dist
Rainbow metamaterials for broadband multi-frequency vibration attenuation: Numerical analysis and experimental validation
In this study, we propose a ‘rainbow’ metamaterial to achieve broadband multi-frequency vibration attenuation. The rainbow metamaterial is constituted of a Π-shaped beam partitioned into substructures by parallel plates insertions with two attached cantilever-mass acting as local resonators. Both resonators inside each substructure can be non-symmetric such that the metamaterial can have multi-frequency bandgaps. Furthermore, these cantilever-mass resonators have a progressively variant design along the beam, namely rainbow-shaped, for the purpose of achieving broader energy stop bands. Π-shaped beams partitioned by parallel plate insertions can be extended to honeycomb sandwich composites, hence the proposed rainbow metamaterial can serve as a precursor for future honeycomb composites with superior vibration attenuation for more industrial applications. A mathematical model is first developed to estimate the frequency response functions of the metamaterial. Interaction forces between resonators and the backbone structure are calculated by solving the displacement of the cantilever-mass resonators. The plate insertions are modeled as attached masses with both their translational and rotational motion considered. Subsequently, the mathematical model is verified by comparison with experimental results. Metamaterials fabricated through an additive manufacturing technique are tested with a laser doppler receptance measuring system. After the validation of the mathematical model, a numerical study is conducted to explore the influences of the resonator spatial distributions on the frequency response functions of structures. Results show that for metamaterials with both symmetric and non-symmetric resonators, rainbow-shaped resonators can introduce inertial forces inside wider frequency range when compared to the periodic resonators of the same total mass, hence broader bandgaps. Meanwhile, the attenuation inside the bandgaps decreases when the bandgap become broader. Metamaterials with broadband multi-frequency range vibration attenuation can be achieved with non-symmetric sinusoidally varying resonators
Glucagon like peptide-1 receptor agonists as neuroprotective agents for ischemic stroke: a systematic scoping review
Stroke mortality and morbidity is expected to rise. Despite considerable recent advances within acute ischemic stroke treatment, scope remains for development of widely applicable neuroprotective agents. Glucagon like peptide-1 receptor agonists (GLP-1RAs), originally licensed for the management of Type 2 Diabetes Mellitus, have demonstrated pre-clinical neuroprotective efficacy in a range of neurodegenerative conditions.
This systematic scoping review reports the pre-clinical basis of GLP-1RAs as neuroprotective agents in acute ischemic stroke and their translation into clinical trials.
We included 35 pre-clinical studies, 11 retrospective database studies, 7 cardiovascular outcome trials and 4 prospective clinical studies.
Pre-clinical neuroprotection was demonstrated in normoglycemic models when administration was delayed by up to 24-hours following stroke induction. Outcomes included reduced infarct volume, apoptosis, oxidative stress and inflammation alongside increased neurogenesis, angiogenesis and cerebral blood flow. Improved neurological function and a trend towards increased survival were also reported.
Cardiovascular outcomes trials reported a significant reduction in stroke incidence with semaglutide and dulaglutide. Retrospective database studies show a trend towards neuroprotection. Prospective interventional clinical trials are on-going, but initial indicators of safety and tolerability are favourable.
Ultimately, we propose that repurposing GLP-1RAs is potentially advantageous but appropriately designed trials are needed to determine clinical efficacy and cost-effectiveness
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