69 research outputs found

    Entrepreneurial Behaviour and Organisational Propensity to Innovate in a Public Sector Context

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    The importance of innovation, in both private and public entrepreneurial fields, is the basis of all companies’ strategic choices. This study examines entrepreneurship and innovation, as well as their dynamic interface in value creation, in the public sector. It explores entrepreneurial determinants for public sector innovation, as collected from managers and employees involved in the water supply and sewage industries in Ukraine. The data, related to a sample of firms, were obtained from a twofold self-administered survey. Adopting an ordered logistic regression model to analyse the data obtained from a survey, it is discovered that the entrepreneurial determinants of self-awareness, knowledge-enabling and entrepreneurial orientation positively correlate with fostering innovation process. The findings reveal that entrepreneurial leadership and intrapreneurial self-efficacy are mediating determinants. Finally, the results demonstrate that intrapreneurial self-efficacy has more potential than entrepreneurial leadership to stimulate innovation at the individual level, which has both theoretical and practical implications

    Digital subtraction radiographic analysis of the combination of bioabsorbable membrane and bovine morphogenetic protein pool in human periodontal infrabony defects

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    Objectives: This study assessed the bone density gain and its relationship with the periodontal clinical parameters in a case series of a regenerative therapy procedure. Material and Methods: Using a split-mouth study design, 10 pairs of infrabony defects from 15 patients were treated with a pool of bovine bone morphogenetic proteins associated with collagen membrane (test sites) or collagen membrane only (control sites). The periodontal healing was clinically and radiographically monitored for six months. Standardized presurgical and 6-month postoperative radiographs were digitized for digital subtraction analysis, which showed relative bone density gain in both groups of 0.034 ± 0.423 and 0.105 ± 0.423 in the test and control group, respectively (p>0.05). Results: As regards the area size of bone density change, the influence of the therapy was detected in 2.5 mm2 in the test group and 2 mm2 in the control group (p>0.05). Additionally, no correlation was observed between the favorable clinical results and the bone density gain measured by digital subtraction radiography (p>0.05). Conclusions: The findings of this study suggest that the clinical benefit of the regenerative therapy observed did not come with significant bone density gains. Long-term evaluation may lead to a different conclusions

    The weekend effect on the provision of Emergency Surgery before and during the COVID-19 pandemic: case–control analysis of a retrospective multicentre database

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    Introduction: The concept of “weekend effect”, that is, substandard healthcare during weekends, has never been fully demonstrated, and the different outcomes of emergency surgical patients admitted during weekends may be due to different conditions at admission and/or different therapeutic approaches. Aim of this international audit was to identify any change of pattern of emergency surgical admissions and treatments during weekends. Furthermore, we aimed at investigating the impact of the COVID-19 pandemic on the alleged “weekend effect”. Methods: The database of the CovidICE-International Study was interrogated, and 6263 patients were selected for analysis. Non-trauma, 18+ yo patients admitted to 45 emergency surgery units in Europe in the months of March–April 2019 and March–April 2020 were included. Demographic and clinical data were anonymised by the referring centre and centrally collected and analysed with a statistical package. This study was endorsed by the Association of Italian Hospital Surgeons (ACOI) and the World Society of Emergency Surgery (WSES). Results: Three-quarters of patients have been admitted during workdays and only 25.7% during weekends. There was no difference in the distribution of gender, age, ASA class and diagnosis during weekends with respect to workdays. The first wave of the COVID pandemic caused a one-third reduction of emergency surgical admission both during workdays and weekends but did not change the relation between workdays and weekends. The treatment was more often surgical for patients admitted during weekends, with no difference between 2019 and 2020, and procedures were more often performed by open surgery. However, patients admitted during weekends had a threefold increased risk of laparoscopy-to-laparotomy conversion (1% vs. 3.4%). Hospital stay was longer in patients admitted during weekends, but those patients had a lower risk of readmission. There was no difference of the rate of rescue surgery between weekends and workdays. Subgroup analysis revealed that interventional procedures for hot gallbladder were less frequently performed on patients admitted during weekends. Conclusions: Our analysis revealed that demographic and clinical profiles of patients admitted during weekends do not differ significantly from workdays, but the therapeutic strategy may be different probably due to lack of availability of services and skillsets during weekends. The first wave of the COVID-19 pandemic did not impact on this difference

    The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

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    AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease

    Modelling the effect of multi-year aphid infestation on fruit production in perennial trees

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    Aphids are commonly considered major agricultural pests because of their ability to alter host plant physiology and impair foliar growth. However, their effect on fruit production in perennial trees did not receive wide attention and few existing works have mainly focused on plant-aphid dynamics in a single growing season (i.e., few months). We modified an existing process based model for the peach tree Prunus persica - aphid Myzus persicae pathosystem, explicitly considering interactions between the two species under the influence of cultural practices (i.e., winter pruning and nitrogen fertilization), in order to consider multi-year dynamics. The new multi-year model suggests that consequences of aphid infestation, in terms of fruit production, become evident only when considering multi-year dynamics

    Corn as trap crop to control <em>Helicoverpa zea</em> in tomato fields: importance of phenological synchronization and choice of cultivar

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    International audienceTrap cropping is an environmentally friendly "alternative" pest management strategy. To maximize the efficiency of corn, Zea mays L. (Poaceae), as a trap crop for Helicoverpa zea (Boddie) (Lepidoptera: Noctuidae), we (i) tested the trap crop potential of corn varieties that are not a source of infestation, and (ii) determined the best corn planting time so as to concentrate H. zea in this trap crop and divert the pest from tomato, Solanum lycopersicum L. (Solanaceae). When corn silk emergence was synchronized with tomato flowering and fresh corn silk was present during the tomato flowering stage, H. zea infestation was lower in the tomato field with a corn border than in those without a corn border. Sugar Jean and Java corn varieties were good trap crops because few larvae persisted on the silks and their growth was low. These two varieties could reduce the risk of H. zea development and dispersion from corn borders
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