Negative affect, perceived health, and endocrine and immunological levels in caregivers of offspring with schizophrenia.

Negative affect (NA) and chronic stress are separately associated with health imbalances, and the interaction between the two aspects remains unclear. Care of relatives with long-term pathologies could be a likely model in the study of this issue, as caregivers frequently report chronic stress and health complaints. The aim of this study is examine the role of NA on psychophysiological stress-induced response and health in schizophrenia caregivers. Method: Forty-one caregivers were distributed into two groups accordingly to their scores in NA. Thirteen non-caregivers were included as a control group. Participants were exposed to a repeated acute psychosocial stress while salivary cortisol, immunoglobulin A (IgA), and skin conductance level (SCL) were measured before, during, and after stress. Mood, state-anxiety, care conditions and perceived general health were also assessed. Results: Caregivers with higher NA reported negative perceptions, worse health, and greater decreases in cortisol and IgA response than caregivers with low NA and than non-caregivers. Conclusions: NA could reduce the capability to develop adaptive psychophysiological stress responses. From a preventive view, the evaluation of NA could be useful to detect and assist high-risk individuals in potentially chronically stressed population

FeAl and NbAl3 intermetallic- HVOF coatings: structure and properties

Transition metal aluminides in their coating form are currently being explored in terms of resistance to oxidation and mechanical behavior. This interest in transition metal aluminides is mainly due to the fact that their high Al content makes them attractive for high-temperature applications. This is also a reason to study their resistance to wear; they may be suitable for use in applications that produce a lot of wear in aggressive environments, thus replacing established coating materials. In this study, the microstructure, microhardness, and wear and oxidation performance of FeAl and NbAl3 coatings produced by highvelocity oxy-fuel spraying are evaluated with two main aims: (i) to compare these two coating systems¿a commonly studied aluminide (FeAl) and, NbAl3, an aluminide whose deposition by thermal spraying has not been attempted to date¿and (ii) to analyze the relationship between their microstructure, composition and properties, and so clarify their wear and oxidation mechanisms. In the present study, the higher hardness of niobium aluminide coatings did not correlate with a higher wear resistance and, finally, although pesting phenomena (disintegration in oxidizing environments) were already known of in bulk niobium aluminides, here their behavior in the coating form is examined. It was shown that such accelerated oxidation was inevitable with respect to the better resistance of FeAl, but further improvements are foreseen by addition of alloying elements in that alloy

The Effect of Atmospheric Pollution on the Thymus

Air pollution is a high-risk factor in megacities’ dwellers because of its effects on health. One of the most important components of the pollution is particulate matter (PM) on which metals are adhered. One element adhered to its surfaces is vanadium (V), and through this route, PM reaches the respiratory system, then the systemic circulation and the rest of the organs. Vanadium is released in the atmosphere as a consequence of the combustion of fossil fuels. Vanadium pentoxide is the compound liberated after the combustion and adhered into PM. Previous studies from our group have reported effects on diverse systems in a mouse model. Besides the morphological changes in the spleen and the decreased function of the immune humoral response, the thymus was also affected. Vanadium inhalation diminished thymic dendritic cells (DCs) and the biomarkers: CD11c and MHCII; in addition, thymic cytoarchitecture changed, demonstrated by cytokeratin-5, and also, modification in the expression of 3-nitrotyrosine was observed. Our findings suggest that autoreactive T cells could be released into the systemic circulation and favor the increase in autoimmune diseases in cities with high concentrations of PM

Epidemiology and spatio‐temporal analysis of West Nile virus in horses in Spain between 2010 and 2016

During the last decade, West Nile virus (WNV) outbreaks have increased sharply in both horses and human in Europe. The aims of this study were to evaluate characteristics and spatio‐temporal distribution of WNV outbreaks in horses in Spain between 2010 and 2016 in order to identify the environmental variables most associated with WNV occurrence and to generate high‐resolution WNV suitability maps to inform risk‐based surveillance strategies in this country. Between August 2010 and November 2016, a total of 403 WNV suspected cases were investigated, of which, 177 (43.9%) were laboratory confirmed. Mean values of morbidity, mortality and case fatality rates were 7.5%, 1.6% and 21.2%, respectively. The most common clinical symptoms were as follows: tiredness/apathy, recumbency, muscular tremor, ataxia, incoordination and hyperaesthesia. The outbreaks confirmed during the last 7 years, with detection of WNV RNA lineage 1 in 2010, 2012, 2013, 2015 and 2016, suggest an endemic circulation of the virus in Spain. The spatio‐temporal distribution of WNV outbreaks in Spain was not homogeneous, as most of them (92.7%) were concentrated in western part of Andalusia (southern Spain) and significant clusters were detected in this region in two non‐consecutive years. These findings were supported by the results of the space–time scan statistics permutation model. A presence‐only MaxEnt ecological niche model was used to generate a suitability map for WNV occurrence in Andalusia. The most important predictors selected by the Ecological Niche Modeling were as follows: mean annual temperature (49.5% contribution), presence of Culex pipiens (19.5% contribution), mean annual precipitation (16.1% contribution) and distance to Ramsar wetlands (14.9% contribution). Our results constitute an important step for understanding WNV emergence and spread in Spain and will provide valuable information for the development of more cost‐effective surveillance and control programmes and improve the protection of horse and human populations in WNV‐endemic areas.info:eu-repo/semantics/acceptedVersio

The effect of hot treatment on composition and microstructure of HVOF iron aluminide coatings in Na2SO4 molten salts

The paper deals with the hot corrosion performance of FeAl base intermetallic HVOF coatings in molten Na2SO4 at 850 C in an isothermal process over the span of 45 h under static conditions. The test was validated with electron microscopy and compositional analyses in the cross-section area, as well as x-ray diffraction techniques. All the coatings were characterized by Al-depleted regions, intersplat oxidation and different stoichiometric ratios of iron aluminides. The results were discussed in relation to the formation of oxide scales on the surface after exposition to corrosive media, as well as heterogeneity and defects of the sprayed coatings. The Fe40Al (at.%) powder showed quite uniform phase distribution after spraying and preserved its integrity after corrosion test; the FeCr25% ? FeAl-TiAl-Al2O3 (wt.%) and Fe46Al-6.55Si (at.%) powders exhibited interface oxidation, with localized corrosion attacks proceeding through particle boundaries and microcrack networks with no evidence of Na and S penetration. FexAly alloys are susceptible to accelerated damage and decohesion of the coating, whereas the formation of sulfides is observed at certain points

Collaborative Learning in Web 2.0: The educational challenge in high school

[EN] The change in higher education caused of ICT have a clear reflection on the methodologies in the university classroom. The technological opportunities and of the easy access to the Internet and information allows both teachers and students to share spaces of the university as ubiquitous environments, facilitating e-learning and blended learning. Social networks such as Facebook, Youtube and other social networks have arrival to the university classroom, both individually and in groups. We present in this paper the results of study whose aim has sought to identify collaborative methodologies in Web 2.0 from the universities of Cadiz, Huelva and Seville. We use a quantitative and qualitative mixed method based on a survey which was responded by 537 students from universities under study. Moreover, it was developed a Focus Group at each university under study, which involved 20 teachers. The results show that collaborative methodologies in university are highly regarded among team members and between them and teachers. However, these collaborative methodologies in Web 2.0 are not used and are hardly used through Web 2.0 tools. In the same direction it is shown that both teachers and university students consider social networks as excellent for collaboration among students and between students and teachers themselves.[ES] El cambio en la Educación Superior provocada por las TIC tiene un reflejo evidente en las metodologías en el aula universitaria. Las posibilidades tecnológicas y de fácil acceso a Internet y a la información permiten que tanto docentes como alumnos compartan espacios de la propia universidad en entornos ubicuos, facilitando el e-learning y blended learning. Las redes sociales como Facebook, Youtube y otras redes sociales han entrado en el aula universitaria, tanto de forma individual como grupal. Este artículo recoge los resultados de la investigación cuyo objetivo ha pretendido identificar metodologías colaborativas en la Web 2.0 de las universidades de Cádiz, Huelva y Sevilla, para ello se utilizó un método mixto cuantitativocualitativo basado en una encuesta a la que respondieron 537 alumnos de las universidades objeto de estudio, por otro lado, se desarrollaron focus group en cada una de las universidades objeto de estudio, en la que participaron 20 docentes. Los resultados obtenidos muestran que las metodologías colaborativas en la universidad están muy bien consideradas entre el alumnado, y los alumnos las utilizan para realizar trabajos en equipo, de la misma forma consideran que las redes sociales mejoran la coordinación entre los miembros del equipo y entre estos y los docentes. Sin embargo, estas metodologías colaborativas en la Web 2.0 no se utilizan y apenas se utilizan a través de las herramientas de la Web 2.0. En la misma dirección se muestran que tanto docentes como alumnos universitarios consideran las redes sociales como excelentes para la colaboración entre los alumnos y entre estos y los propios docentes.Rodrigo-Cano, D.; Aguaded Gómez, I.; García Moro, F. (2019). Metodologías colaborativas en la Web 2.0. El reto educativo de la Universidad. REDU. Revista de Docencia Universitaria. 17(1):229-244. https://doi.org/10.4995/redu.2019.10829SWORD22924417

Influence of Cold Gas Spray process conditions on the microstructure of Fe-based amorphous coatings

Fe-based amorphous metallic coatings were prepared by Cold Gas Spray process. Through this study, the effects of the process conditions such as spraying distance, gas pressure and temperature on the microstructure of as-sprayed coatings are evaluated. Microstructural studies show that the coatings can present a densely layered structure with porosity below 0.5% and thickness around 800 μm depending on the process conditions. Precipitation of nanocrystals in as-sprayed coatings is observed and present results show its dependence on the thermal and kinetic energy implicated in the process. In general, when gas temperature and pressure decreased, in the studied range, coatings displayed a dense and amorphous structure