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Transparent 2-Element 5G MIMO Antenna for Sub-6 GHz Applications
YesA dual-port transparent multiple-input multiple-output (MIMO) antenna resonating at sub-6 GHz 5G band is proposed by using patch/ground material as transparent conductive oxide (AgHT-8) and a transparent Plexiglas substrate. Two identical circular-shaped radiating elements fed by using a microstrip feedline are designed using the finite element method (FEM) based highfrequency structure simulator (HFSS) software. The effect of the isolation mechanism is discussed using two cases. In case 1, the two horizontally positioned elements are oriented in a similar direction with a separate ground plane, whereas in case 2, the elements are vertically placed facing opposite to each other with an allied ground. In both cases, the transparent antennas span over a −10 dB band of 4.65 to 4.97 GHz (300 MHz) with isolation greater than 15 dB among two elements. The diversity parameters are also analyzed for both the cases covering the correlation coefficient (ECC), mean effective gain (MEG), diversity gain (DG), and channel capacity loss (CCL). The average gain and efficiency above 1 dBi and 45%, respectively with satisfactory MIMO diversity performance, makes the transparent MIMO antenna an appropriate choice for smart IoT devices working in the sub-6 GHz 5G band by mitigating the co-site location and visual clutter issues.This work is supported by the Moore4Medical project, funded within ECSEL JU in collaboration with the EU H2020 Framework Programme (H2020/2014-2020) under grant agreement H2020-ECSEL-2019-IA-876190, and Fundação para a Ciência e Tecnologia (ECSEL/0006/2019)
Structure and photophysics of indigoids for singlet fission: Cibalackrot
We report an investigation of structure and photophysics of thin layers of cibalackrot, a sturdy dye derived from indigo by double annulation at the central double bond. Evaporated layers contain up to three phases, two crystalline and one amorphous. Relative amounts of all three have been determined by a combination of X-ray diffraction and FT-IR reflectance spectroscopy. Initially, excited singlet state rapidly produces a high yield of a transient intermediate whose spectral properties are compatible with charge-transfer nature. This intermediate more slowly converts to a significant yield of triplet, which, however, does not exceed 100% and may well be produced by intersystem crossing rather than singlet fission. The yields were determined by transient absorption spectroscopy and corrected for effects of partial sample alignment by a simple generally applicable procedure. Formation of excimers was also observed. In order to obtain guidance for improving molecular packing by a minor structural modification, calculations by a simplified frontier orbital method were used to find all local maxima of singlet fission rate as a function of geometry of a molecular pair. The method was tested at 48 maxima by comparison with the ab initio Frenkel-Davydov exciton model. Published under license by AIP Publishing
Long term hemodialysis aggravates lipolytic activity reduction and very low density, low density lipoproteins composition in chronic renal failure patients
<p>Abstract</p> <p>Background</p> <p>Dyslipidemia, particularly hypertriglyceridemia is common in uremia, and represents an independent risk factor for atherosclerosis.</p> <p>Methods</p> <p>To investigate the effects of hemodialysis (HD) duration on very low density lipoprotein (VLDL) and low density lipoprotein (LDL) compositions and lipopolytic activities, 20 patients on 5 to 7 years hemodialysis were followed-up during 9 years. Blood samples were drawn at T0 (beginning of the study), T1 (3 years after initiating study), T2 (6 years after initiating study) and T3 (9 years after initiating study). T0 was taken as reference.</p> <p>Results</p> <p>Triacylglycerols (TG) values were correlated with HD duration (r = 0.70, P < 0.05). An increase of total cholesterol was noted at T2 and T3. Lowered activity was observed for lipoprotein lipase (LPL) (-44%) at T3 and hepatic lipase (HL) (-29%) at T1, (-64%) at T2 and (-73%) at T3. Inverse relationships were found between HD duration and LPL activity (r = -0.63, P < 0.05), and HL activity (r = -0.71, P < 0.01). At T1, T2 and T3, high VLDL-amounts and VLDL-TG and decreased VLDL-phospholipids values were noted. Increased LDL-cholesteryl esters values were noted at T1 and T2 and in LDL-unesterified cholesterol at T2 and T3.</p> <p>Conclusion</p> <p>Despite hemodialysis duration, VLDL-LDL metabolism alterations are aggravated submitting patients to a greater risk of atherosclerosis.</p
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behcet's disease
Behcet's disease is a genetically complex disease of unknown etiology characterized by recurrent inflammatory attacks affecting the orogenital mucosa, eyes and skin. We performed a genome-wide association study with 311,459 SNPs in 1,215 individuals with Behcet's disease (cases) and 1,278 healthy controls from Turkey. We confirmed the known association of Behcet's disease with HLA-B*51 and identified a second, independent association within the MHC Class I region. We also identified an association at IL10 (rs1518111, P = 1.88 x 10(-8)). Using a meta-analysis with an additional five cohorts from Turkey, the Middle East, Europe and Asia, comprising a total of 2,430 cases and 2,660 controls, we identified associations at IL10 (rs1518111, P = 3.54 x 10(-18), odds ratio = 1.45, 95% CI 1.34-1.58) and the IL23R-IL12RB2 locus (rs924080, P = 6.69 x 10(-9), OR = 1.28, 95% CI 1.18-1.39). The disease-associated IL10 variant (the rs1518111 A allele) was associated with diminished mRNA expression and low protein production
Does the unification of health financing affect the distribution pattern of out‐of‐pocket health expenses in Turkey?
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149529/1/ijsw12389_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149529/2/ijsw12389.pd
Clinical Use and Therapeutic Potential of IVIG/SCIG, Plasma-Derived IgA or IgM, and Other Alternative Immunoglobulin Preparations
Intravenous and subcutaneous immunoglobulin preparations, consisting of IgG class antibodies, are increasingly used to treat a broad range of pathological conditions, including humoral immune deficiencies, as well as acute and chronic inflammatory or autoimmune disorders. A plethora of Fab- or Fc-mediated immune regulatory mechanisms has been described that might act separately or in concert, depending on pathogenesis or stage of clinical condition. Attempts have been undertaken to improve the efficacy of polyclonal IgG preparations, including the identification of relevant subfractions, mild chemical modification of molecules, or modification of carbohydrate side chains. Furthermore, plasma-derived IgA or IgM preparations may exhibit characteristics that might be exploited therapeutically. The need for improved treatment strategies without increase in plasma demand is a goal and might be achieved by more optimal use of plasma-derived proteins, including the IgA and the IgM fractions. This article provides an overview on the current knowledge and future strategies to improve the efficacy of regular IgG preparations and discusses the potential of human plasma-derived IgA, IgM, and preparations composed of mixtures of IgG, IgA, and IgM
Artificial neural network (ANN) approach for modelling of pile settlement of open-ended steel piles subjected to compression load
This study was devoted to examine pile bearing capacity and to provide a reliable model to simulate pile load-settlement behaviour using a new artificial neural network (ANN) method. To achieve the planned aim, experimental pile load test were carried out on model open-ended steel piles, with pile aspect ratios of 12, 17, and 25. An optimised second-order Levenberg-Marquardt (LM) training algorithm has been used in this process. The piles were driven in three sand densities; dense, medium, and loose. A statistical analysis test was conducted to explore the relative importance and the statistical contribution (Beta and Sig) values of the independent variables on the model output. Pile effective length, pile flexural rigidity, applied load, sand-pile friction angle and pile aspect ratio have been identified to be the most effective parameters on model output. To demonstrate the effectiveness of the proposed algorithm, a graphical comparison was performed between the implemented algorithm and the most conventional pile capacity design approaches. The proficiency metric indicators demonstrated an outstanding agreement between the measured and predicted pile-load settlement, thus yielding a correlation coefficient (R) and root mean square error (RMSE) of 0.99, 0.043 respectively, with a relatively insignificant mean square error level (MSE) of 0.0019. © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group
Clinically Significant Pharmacokinetic Interaction between Colchicine and Ritonavir in Healthy Volunteers
Retrospective analysis of live birth prevalence of children with Down syndrome in Denizli, Turkey.
Down syndrome (DS) is the most frequent chromosome abnormality among live births. Its prevalence increases with maternal age, and can be diagnosed by antenatal screening. We examined prevalence variations of DS in Denizli, Turkey, through a retrospective study. Sixteen years of survey data were retrieved from the two main state hospital registries from records between 1994 and 2010. We identified 113 DS live births in Denizli for 16 years. The prevalence of DS was 9.07 per 10,000 live births before the year 2000 and 9.90 after 2000. The prevalence did not change significantly. The population in Turkey is still young; the fertility rate is high in women under 35 years old and prenatal screening programs are extensively applied; for these reasons, the prevalence of DS has remained stable during these 16 years
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