A new class of plane symmetric solution

A new class of static plane symmetric solution of Einstein field equation generated by a perfect fluid source is put forward. A special family of this new solution is investigated in detail. The constraints on the parameters by different energy conditions are studied. The classical stability of this solution is discussed. The junction conditions matching to Minkowski metric and Taub metric are analyzed respectively.Comment: 10 pages, v2: a typo in equation (37) corrected, v3: equation (68) corrected, PLB V663, Pages 291-29

Does Unruh radiation accelerate the universe? A novel approach to the cosmic acceleration

We present a novel mechanism for the present acceleration of the universe. We find that the temperature of the Unruh radiation perceived by the brane is not equal to the inherent temperature (Hawking temperature at the apparent horizon) of the brane universe in the frame of Dvali-Gabadadze-Porrati (DGP) braneworld model. The Unruh radiation perceived by a dust dominated brane is always warmer than the brane measured by the geometric temperature, which naturally induces an energy flow between bulk and brane based on the most sound thermodynamics principles. Through a thorough investigation to the microscopic mechanism of interaction between bulk Unruh radiation and brane matter, we put forward that an energy influx from bulk Unruh radiation to the dust matter on the brane accelerates the universe.Comment: 28 pages, 4 figs, to appear in NPB; This is a joint paper of hep-th/0607166 and astro-ph/0607531, which will be withdraw

Application of the Khorana score for cancer-associated thrombosis prediction in patients of East Asian ethnicity undergoing ambulatory chemotherapy

Background The Khorana score (KS) has not been well studied in East Asian cancer patients, who have different genetic backgrounds for inherited thrombophilia, body metabolism, and cancer epidemiology. Methods By using the Common Data Model, we retrospectively collected deidentified data from 11,714 consecutive newly diagnosed cancer patients who underwent first-line chemotherapy from December 2015 to December 2021 at a single institution in Korea, and we applied the KS for cancer-associated thrombosis (CAT) prediction. Age at diagnosis, sex, and use of highly thrombogenic chemotherapeutics were additionally investigated as potential risk factors for CAT development. Results By 6 months after chemotherapy initiation, 207 patients (1.77%) experienced CAT. Only 0.4% had a body mass index (BMI) ≥ 35 kg/m2 and changing the cutoff to 25 kg/m2 improved the prediction of CAT. Age ≥ 65 years and the use of highly thrombogenic chemotherapeutics were independently associated with CAT development. KS values of 1 ~ 2 and ≥ 3 accounted for 52.3% and 7.6% of all patients, respectively, and the incidence of CAT in these groups was 2.16% and 4.16%, respectively, suggesting a lower incidence of CAT in the study population than in Westerners. The KS component regarding the site of cancer showed a good association with CAT development but needed some improvement. Conclusion The KS was partially validated to predict CAT in Korean cancer patients undergoing modern chemotherapy. Modifying the BMI cutoff, adding other risk variables, and refining the use of cancer-site data for CAT risk prediction may improve the performance of the KS for CAT prediction in East Asian patients.This work was supported by the Technology Innovation Program (or Industrial Strategic Technology Development Program) (20004927, Upgrade of CDM based Distributed Biohealth Data Platform and Development of Verification Technology), funded by the Ministry of Trade, Industry & Energy (MOTIE, Korea). The funder was not involved in any stage of the current study, including the design, data gathering, data analysis and interpretation, and decision to submit this work for publication

Probing the nature of cosmic acceleration

The cosmic acceleration is one of the most significant cosmological discoveries over the last century. The two categories of explanation are exotic component (dark energy) and modified gravity. We constrain the two types of model by a joint analysis with perturbation growth and direct $H(z)$ data. Though the minimal $\chi^2$ of the $\Lambda$CDM is almost the same as that of DGP, in the sense of consistency we find that the dark energy ($\Lambda$CDM) model is more favored through a detailed comparison with the corresponding parameters fitted by expansion data.Comment: 10 pages, 6 figures, typo correcte

Synthesis of heterocyclic-fused benzofurans via C–H functionalization of flavones and coumarins

An efficient method to effect C–O cyclization was developed via the C–H functionalization of chromones and coumarins, affording heterocyclic-fused benzofurans.124281sciescopu

TEM analysis of DR1 strains.

<p>Microscopic images were obtained by transmission electron microscopy (TEM). Cells were cut into 70-nm-thick sections and double stained with uranyl acetate and lead citrate for contrast staining. The cross-section of each specimen is displayed in a small box alongside the longitudinal section. Bar indicates 250 nm.</p

Expression profile of bacterial fimbriae-related genes.

<p>Expression profile of bacterial fimbriae-related genes.</p

Fitness cost of plasmid-mediated tetracycline resistance.

<p>(A) Fitness by long-term survival of wild-type DR1 and DR1 (pAST2) in mixed cultures under test conditions. Norfloxacin and hydrogen peroxide were supplemented with sub-inhibitory concentrations in nutrient media. (B) Fitness under TC-treated conditions. The relative fitness is expressed as the ratio of DR1 (pAST2) to wild-type (fitness value; 1.0). Quantitative data were obtained from two independent mixed cultures.</p

Gene expression (fold change) values of genes related to transcription, ATPase, ATP synthase, and hexadecane degradation.

<p>Gene expression (fold change) values of genes related to transcription, ATPase, ATP synthase, and hexadecane degradation.</p