Structural Efficiency of Steel Stiffening Deck Systems in Suspension Bridges Due to Gravity Loads

In this paper, suspended stiffened decks in suspension bridges are considered. Three steel deck-stiffening systems are compared structurally; the plate girder, the box girder and the stiffening truss. A three-span continuous suspension bridge model is considered. Analysis is made by the second order non-linear deflection theory in its linearized form. Developed software is used for the analysis to determine the induced tension in the cable, moments, shears and deflections of the girders for any general live load case. AASHTO criteria for steel girders are adopted. AASHTO highway live loads -HL 93- are applied to Khartoum-Tuti Suspension Bridge in Khartoum, Sudan for each type of the stiffening systems. Ten load cases are considered and discussed. Results have shown that the most efficient type to resist gravity loads is the stiffening truss, followed by the box girder and last is the plate girde

Cress Seed (Lepidium sativum) Role in the healthy Processed Spread Cheese and Its Anti-Diabetic Activity

The present study dealt with utilization of cress seeds (Lepidium sativum) in the manufacture of processed spread cheese, instead of emulsifying salt. Cress seed have also health promoting properties especially lowering glucose ratios. Cress seeds powder were prepared and added with the ingredients during manufacture of processed spread cheese at levels of six ratios (0.05, 1.5, 2.5, 3.5, 4.5 and 5.5%) compared with control (3% commercial emulsifying salt). The chemical, physical, microbiology and organoleptic properties of resultant samples were evaluated. Data revealed that processed spread cheese sample fortified with 3.5% cress seeds was the best either when fresh or during storage (8±2ºC for 3 months) and they had acceptable properties. Microstructure of processed cheese spread samples were also conducted. From nutritional view, processed cheese spread samples fortified with 3.5% cress seeds were used for feeding Adult male albino rats to study their effect on plasma glucose level. Obtained data indicated that the glucose level in plasma was significantly decreased (

Cyclic Self-Organizing Map for Object Recognition

Object recognition is an important machine learning (ML) application. To have a robust ML application, we need three major steps: (1) preprocessing (i.e. preparing the data for the ML algorithms); (2) using appropriate segmentation and feature extraction algorithms to abstract the core features data and (3) applying feature classification or feature recognition algorithms. The quality of the ML algorithm depends on a good representation of the data. Data representation requires the extraction of features with an appropriate learning rate. Learning rate influences how the algorithm will learn about the data or how the data will be processed and treated. Generally, this parameter is found on a trial-and-error basis and scholars sometimes set it to be constant. This paper presents a new optimization technique for object recognition problems called Cyclic-SOM by accelerating the learning process of the self-organizing map (SOM) using a non-constant learning rate. SOM uses the Euclidean distance to measure the similarity between the inputs and the features maps. Our algorithm considers image correlation using mean absolute difference instead of traditional Euclidean distance. It uses cyclical learning rates to get high performance with a better recognition rate. Cyclic-SOM possesses the following merits: (1) it accelerates the learning process and eliminates the need to experimentally find the best values and schedule for the learning rates; (2) it offers one form of improvement in both results and training; (3) it requires no manual tuning of the learning rate and appears robust to noisy gradient information, different model architecture choices, various data modalities and selection of hyper-parameters and (4) it shows promising results compared to other methods on different datasets. Three wide benchmark databases illustrate the efficiency of the proposed technique: AHD Base for Arabic digits, MNIST for English digits, and CMU-PIE for faces

Approach for Diagnosis of Complicated Traumatic Reticuloperitonitis in Cattle using Ultrasonography

The current study indicated that the complicated sequellae of traumatic reticuloperitonitis (TRP) in cattle could be efficiently diagnosed by using of ultrasonography and some other diagnostic tools. The affections in these cases included reticulum and spleen with extension to one or more of the other organs such as rumen and abomasum. This study included two groups of animals; one of them kept as a control one (n.=16) and the other was a diseased group (n.= 12). All animals were subjected to clinical examination, whole blood profiling, blood serum biochemical assay, radiography and ultrasonographic examination. Rumenotomy was carried out in some cases. The reticulum was mostly displaced in cases of complicated TRP by a distance of 3-6 cm. Sometimes, the reticulum was not displaced such as in case of diaphragmatic hernia. The reticular contractions in the complicated traumatic cows were either reduced to 2 or 1/3mins, or completely reduced to 0/3mins. Reticular abscess and peritoneal effusions were imaged in all these diseased cases. Here, Vagus indigestion syndrome and diaphragmatic hernia were successfully diagnosed by using of ultrasonography with the aid of radiography and rumenotomy. Ultrasonography was useful in imaging non metal objects (Ropes and plastic tubes) within the rumen especially in cases of severe ruminal distension

Efficacy of oral celecoxib and hyoscine butyl-bromide versus placebo during copper intrauterine device placement in women delivered only by elective cesarean section: a randomized controlled study

Objective: To compare the efficacy and tolerability of celecoxib to hyoscine butyl bromide (HBB) and placebo in reducing pain scores during placement of copper intrauterine devices (IUD) in parous women who have undergone elective cesarean section and who have had no previous vaginal deliveries. Methods: We conducted a randomized, double-blind, placebo-controlled trial at a tertiary University hospital from April 2018 to September 2018. The study included women who had never delivered vaginally and who desired copper IUD insertion. We randomized the study participants in a 1:1:1 ratio to celecoxib, HBB or placebo groups. They took the tablets orally two hours before IUD insertion. The study outcomes were the self-reported pain measurements, using a 10-cm Visual Analogue Scale (VAS), taken during tenaculum placement, sound insertion, IUD insertion and five minutes post-insertion, as well as an ease of insertion score. Results: The study included 105 women (n=35 in each group). The baseline characteristics were similar among all groups. The mean pain score in the celecoxib group was lower during IUD insertion than placebo (1.97 vs 4.34, p<0.001). Moreover, the ease of insertion score was significantly better with celecoxib [1.56 vs. 3.03, p< 0.001] than with placebo. Similarly, Women in the HBB group were more likely to report lower pain scores during IUD insertion (2.91 vs 4.34, p<0.001) and lower ease of insertion score [1.43 vs. 3.03, p< 0.001]. Conclusions: The use of celecoxib and HBB may both reduce the pain associated with copper IUD insertion among women with no previous vaginal delivery. However, celecoxib is better tolerated with fewer side effect

Cathepsin b: a potential prognostic marker for inflammatory breast cancer

<p>Abstract</p> <p>Background</p> <p>Inflammatory breast cancer (IBC) is the most aggressive form of breast cancer. In non-IBC, the cysteine protease cathepsin B (CTSB) is known to be involved in cancer progression and invasion; however, very little is known about its role in IBC.</p> <p>Methods</p> <p>In this study, we enrolled 23 IBC and 27 non-IBC patients. All patient tissues used for analysis were from untreated patients. Using immunohistochemistry and immunoblotting, we assessed the levels of expression of CTSB in IBC versus non-IBC patient tissues. Previously, we found that CTSB is localized to caveolar membrane microdomains in cancer cell lines including IBC, and therefore, we also examined the expression of caveolin-1 (cav-1), a structural protein of caveolae in IBC versus non-IBC tissues. In addition, we tested the correlation between the expression of CTSB and cav-1 and the number of positive metastatic lymph nodes in both patient groups.</p> <p>Results</p> <p>Our results revealed that CTSB and cav-1 were overexpressed in IBC as compared to non-IBC tissues. Moreover, there was a significant positive correlation between the expression of CTSB and the number of positive metastatic lymph nodes in IBC.</p> <p>Conclusions</p> <p>CTSB may initiate proteolytic pathways crucial for IBC invasion. Thus, our data demonstrate that CTSB may be a potential prognostic marker for lymph node metastasis in IBC.</p

Detection of HER-2/neu, c-myc amplification and p53 inactivation by FISH in Egyptian patients with breast cancer

Breast cancer is a leading cause of cancer-related deaths in women worldwide. The clinical course of this disease is highly variable and clinicians continuously search for prognostic parameters that can accurately predict prognosis, and indicate a suitable adjuvant therapy for each patient. Amplification of the two oncogenes HER-2/neu and c-myc and inactivation of the tumor suppressor gene p53 are frequently encountered in breast carcinomas. The purpose of this study was to use the fluorescence in situ hybridization (FISH) for the assessment of HER-2/neu and c-myc amplification and p53 inactivation and to relate these molecular markers with the commonly used clinical and pathological factors. The study was conducted on 34 tissue samples obtained from 33 females and 1 male with breast carcinomas and 17 samples obtained from 16 females and 1 male with benign breast lesions. Results revealed that the level of HER-2/neu, c-myc and p53 in the malignant group was significantly increased as compared to the benign group. On relating the level of the molecular markers to clinicopathological factors, p53 was significantly associated with increased patient’s age. The sensitivity of the investigated markers significantly increased with larger tumor size. Concerning tumor grade, HER-2/neu and p53 showed a significant increase in low-grade tumors whereas c-myc showed a highly significant increase in high-grade tumors. With regard to disease staging, HER-2/neu and c-myc were the only markers that showed significant increase at late stages of disease. p53 and HER-2/neu were significantly associated with positive lymph nodal status. A significant correlation was obtained between the levels of the three biomarkers to each other. Conclusively, the combination of HER-2/neu, c-myc and p53 can stratify patients into different risk groups

User friendly system for the visually impaired in learning Al-Quran

This study presents a method to enable the visually impaired Muslim to learn and read the Al-Quran using Braille Display with software help. The system reads the database which contains all verses of Al-Quran and user will need to select the verse and ayah to read. Besides that, this system can be used in a class to teach visually impaired students to learn Al-Quran. Every word or character typed by the instructor in the main Braille Panel will be transmitted to the sub Braille Panel that is connected to the main Braille Panel. The selected verse of Al-Quran and ayah will also generate an index before being transmitted to the Braille Panel. The index will be transmitted to the Braille Display for people to touch and read the display. A user friendly Graphical User Interface (GUI) will be used to fulfill the ergonomics for the visually impaired user's physical capabilities. Several approaches are used to design and implement the interface for the visually impaired like speech or sound output and Braille display. The Braille codes can be displayed using the Braille panel. The design interface and structure of the system for the visually impaired users in learning Al-Quran is presented