Pharmacological Therapy of Ascites

Ascites refer to accumulation of fluids in the peritoneal cavity. Ascites is caused by multiple causes, among which liver cirrhosis is the commonest. Confirming the etiology is the first and most important step toward proper management. Assuming that ascites is always caused by cirrhosis can lead to unnecessarily sending patients with different etiologies for liver transplantation, particularly patients with non-cirrhotic portal hypertension. Calculating serum albumin ascitic gradient is important in differentiating ascites due to portal hypertension from other etiologies. The first-line therapy for ascites in cirrhosis is low salt diet and diuretics. It is important to avoid nonsteroidal anti-inflammatory drugs (NSAIDs) and nephrotoxic medications in these patients

Throughput, Spectral, and Energy Efficiency of 5G Massive MIMO Applications Using Different Linear Precoding Schemes

— A promising massive multiple input multiple output (M-MIMO) system is required to meet the growing need for highly traffic data, highly-resolution of streaming video, and intelligent communication on the fifth-generation wireless networks (5G). M-MIMO systems are essential for the optimization of the trade between energy efficiency (EE), throughput (R), and spectral _efficiency (SE) in wireless 5G networks. M-MIMO system architecture is proposed in this paper to enhance the trade-off between energy efficiency and uplink and downlink throughput at the optimum EE. Furthermore, using linear precoding techniques such as M MMSE, RZF, ZF, and MR, the EE-SE trade-off is optimized for uplink and downlink (M-MIMO) systems. The analysis of simulation results proved that throughput (R) is enhanced by increasing the number of antennas at optimum EE. After that, the proposed trading scheme is optimized and improved using M_MMSE compared to RZF, ZF. Finally, the results prove that M_MMSE gives the optimum trade-off between EE and R at the proved optimum ratio between the number of active antennas and the number of active users UE

The problems faced by teachers in institutes of teaching Arabic to non-native speakers from their point of view ((Study in institutes of teaching Arabic for non-native speakers in Damascus))

The study aimed to identify the problems faced by teachers of Arabic language in the institutes of teaching Arabic language to non-native speakers during their work, and to investigate the impact of both gender variables and years of experience in the degree of appreciation of these problems by applying a questionnaire consisting of (24) The results of the study showed that the estimates of the teachers of the Arabic language (Arabic, Arabic, English, Arabic, English, Arabic, and Arabic) (2.58), and their assessment of the linguistic problems they face while performing their work came to a medium degree with a mean average of 1.54, and their assessment of the problems encountered during the course of their work was high and with an average of (2.06). The results of the study did not show the effect of sex variables and years of experience in the estimates of Arabic language teachers on the problems they face while doing their work

Noise Effects on a Proposed Algorithm for Signal Reconstruction and Bandwidth Optimization

The development of wireless technology in recent years has increased the demand for channel resources within a limited spectrum. The system\u27s performance can be improved through bandwidth optimization, as the spectrum is a scarce resource. To reconstruct the signal, given incomplete knowledge about the original signal, signal reconstruction algorithms are needed. In this paper, we propose a new scheme for reducing the effect of adding additive white Gaussian noise (AWGN) using a noise reject filter (NRF) on a previously discussed algorithm for baseband signal transmission and reconstruction that can reconstruct most of the signal’s energy without any need to send most of the signal’s concentrated power like the conventional methods, thus achieving bandwidth optimization. The proposed scheme for noise reduction was tested for a pulse signal and stream of pulses with different rates (2, 4, 6, and 8 Mbps) and showed good reconstruction performance in terms of the normalized mean squared error (NMSE) and achieved an average enhancement of around 48%. The proposed schemes for signal reconstruction and noise reduction can be applied to different applications, such as ultra-wideband (UWB) communications, radio frequency identification (RFID) systems, mobile communication networks, and radar systems

Antibacterial, antioxidant, wound healing activities and stop-bleeding effect of methanolic extract of Tridax procumbens L. leaves

Tridax procumbens is a leafy herb commonly used in different traditional treatments in many countries including Yemen. The main aim of the present study is evaluating some specific biological activities (antibacterial, antiradical, wound healing potential and stop- bleeding effect) of methanolic (MeOH) extract of T. procumbens leaves collected from Yemen. Antibacterial effect was examined by paper disc diffusion method against different bacterial species, antioxidant was evaluated in vitro against 1,1-diphenyl-2-picryhydrazyl (DPPH) radicals, wound healing and stop-bleeding were evaluated in experimental animals. Phytochemicals were screened by qualitative standard methods. Results showed that, MeOH extract of T. procumbens exhibited a strong anti-DPPH radical effect with IC50 value 151.23 µg/mL. Antibacterial activity was only observed against Klebsiella pneumoniae with the highest inhibition zone 16 mm by 100 mg/mL of extract. Completely healing for wounds treated with 50 mg/mL, 25mg/mL and 12.5mg/mL of extract was observed on the 11th day of treatment and the treatment applications with plant extract (50 mg/mL, 25mg/mL and 12.5mg/mL) significantly (P<0.05) reduced the time of bleeding by 50% compare to control. Major bioactive phytochemicals were detected in MeOH extract of T. procumbens. The obtained results in this study indicated that, T. procumbens could be used as natural source for many forms of pharmacological preparations. Further clinical and toxicological studies are recommended

SAPONINS, GLYCOSIDES AND FLAVONOIDS IN CELLS AND TISSUES OF BALANITES AEGYPTIACA CULTURED ON SOLID AND LIQUID CULTURE MEDIA

Objectives: The main objective of the present study is to obtain callus and cell suspension culture from Balanitesa egyptiaca sterile plantlets grown in vitro and to compare growth and the biosynthetic potential of saponins, flavonoids and glycosides by callus and cell suspension culture Balanitisa egyptiaca. Methods: Callus was induced from the mother plants on MS culture media supplemented with  2.0 mg/l  BA + 2.0 mg/l  2,4-D with and without agar gelling. Total saponins, glycosides and flavonoids were estimated in both types of cultures over a period extending from 1 to 5 weeks to compare the productivity of such secondary metabolites in callus and cell suspension cultures. Results: The results obtained indicated that both calli and cell suspension cultures were able to synthesize the target active ingredients and that cell suspension culture was superior to the callus culture in the biosynthesis and accumulation processes. By the end of the incubation period, the amount of total saponins in cell suspension culture reached up 51.97±0.26 dry biomass compared to 35.02 ±0.06 mg/g in callus culture. The amount of total flavonoids in cell suspension culture reached up 10.88±0.24 dry biomass compared to 6.40±0.02 mg/g in callus culture and of total glycosides reached up 6.11±0.25 dry biomass compared to 5.06 ±0.05 mg/g in callus culture. Conclusions: The results obtained in this study may indicate the promising role that plant cell culture will play in the future in phytopharmaceutical industry.                          Peer Review History: Received 16 July 2020; Revised 12 August; Accepted 26 August, Available online 15 September 2020 Academic Editor: Dr. Iman Muhammad Higazy, National Research Center, Egypt, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.  Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Dr. Gehan Fawzy Abdel Raoof Kandeel, Researcher at pharmacognosy Department, National Research Centre, Egypt, [email protected] Ahmad Najib, Department of Pharmacognosy-Phytochemystry Universitas Muslim Indonesia-Indonesia, [email protected] Similar Articles: PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF COLOCASIA ESCULENTA (TARO) MEDICINAL PLANT LEAVES USED IN FOLK MEDICINE FOR TREATMENT OF WOUNDS AND BURNS IN HUFASH DISTRICT AL MAHWEET GOVERNORATE–YEMEN PHYTOCHEMICAL SCREENING AND THIN LAYER CHROMATOGRAPHIC OF PRUNUS DULCIS (ALMOND) MEDICINAL PLANT LEAVES USED IN FOLK MEDICINE FOR TREATMENT OF WOUNDS AND BURNS IN HUFASH DISTRICT AL MAHWEET GOVERNORATE–YEME

Hiding data in images using steganography techniques with compression algorithms

Steganography is the science and art of secret communication between two sides that attempt to hide the content of the message. It is the science of embedding information into the cover image without causing a loss in the cover image after embedding.Steganography is the art and technology of writing hidden messages in such a manner that no person, apart from the sender and supposed recipient, suspects the lifestyles of the message. It is gaining huge attention these days as it does now not attract attention to its information's existence. In this paper, a comparison of two different techniques is given. The first technique used Least Significant Bit (LSB) with no encryption and no compression. In the second technique, the secret message is encrypted first then LSB technique is applied. Moreover, Discrete Cosine Transform (DCT) is used to transform the image into the frequency domain. The LSB algorithm is implemented in spatial domain in which the payload bits are inserted into the least significant bits of cover image to develop the stego-image while DCT algorithm is implemented in frequency domain in which the stego-image is transformed from spatial domain to the frequency domain and the payload bits are inserted into the frequency components of the cover image.The performance of these two techniques is evaluated on the basis of the parameters MSE and PSNR

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

INTRODUCTION Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic. RATIONALE We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs). RESULTS Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants. CONCLUSION Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century

An in-vitro study of human dentine using ac-impedence spectroscopy : a grounded theory study of client and provider perspectives

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