8 research outputs found
Carbon-doped flower-like Bi2WO6 decorated carbon nanosphere nanocomposites with enhanced visible light photocatalytic degradation of tetracycline
In search of a recyclable catalyst with synergistic adsorption and photocatalysis, unique composite photocatalysts of flower-like bismuth tungstate (Bi2WO6) and carbon nanospheres (CSs) were composited using a hydrothermal synthesis method (named CSs-Bi2WO6). Notably, based on the high visible light utilization and a reasonable band gap (2.53 eV), CSs-Bi2WO6 have good photocatalytic properties. For example, the composite with an optimized ratio (2% CSs-Bi2WO6) showed good adsorption and photocatalytic performance. Under simulated natural light conditions, the degradation rate of tetracycline (TC) by 2% CSs-Bi2WO6 was 84.6% in 60 min, which is nearly 25% higher than pure Bi2WO6. After five cycles, the observed barely decreased TC degradation rate of 2% CSs-Bi2WO6 confirmed the high cyclability and reproducibility of the photocatalyst. The total organic carbon estimation of the post-degradation reaction medium corresponded to 68.2% mineralization. Furthermore, we determined the photocatalytic reaction path by LC–MS, which confirmed that the composite catalyst could effectively degrade TC molecules into small molecules. It can be concluded that the catalyst has a broad application prospect in the field of wastewater treatment
Oxygenic Hybrid Semiconducting Nanoparticles for Enhanced Photodynamic Therapy
Photodynamic nanotheranostics
has shown great promise for cancer
therapy; however, its therapeutic efficacy is limited due to the hypoxia
of tumor microenvironment and the unfavorable bioavailability of existing
photodynamic agents. We herein develop hybrid core–shell semiconducting
nanoparticles (SPN-Ms) that can undergo O<sub>2</sub> evolution in
hypoxic solid tumor to promote photodynamic process. Such oxygenic
nanoparticles are synthesized through a one-pot surface growth reaction
and have a unique multilayer structure cored and coated with semiconducting
polymer nanoparticles (SPNs) and manganese dioxide (MnO<sub>2</sub>) nanosheets, respectively. The SPN core serves as both NIR fluorescence
imaging and photodynamic agent, while the MnO<sub>2</sub> nanosheets
act as a sacrificing component to convert H<sub>2</sub>O<sub>2</sub> to O<sub>2</sub> under hypoxic and acidic tumor microenvironment.
As compared with the uncoated SPN (SPN-0), the oxygenic nanoparticles
(SPN-M1) generate 2.68-fold more <sup>1</sup>O<sub>2</sub> at hypoxic
and acidic conditions under NIR laser irradiation at 808 nm. Because
of such an oxygen-evolution property, SPN-M1 can effectively eradicate
cancer cells both in vitro and in vivo. Our study thus not only reports
an in situ synthetic method to coat organic nanoparticles but also
develops a tumor-microenvironment-sensitive theranostic nanoagent
to overcome hypoxia for amplified therapy
Unexpected selective alkaline periodate oxidation of chitin for the isolation of chitin nanocrystals
Periodate oxidation reaction occurring directly on chitin has been
neglected in polysaccharide chemistry so far. Herein, we present
the first direct alkaline periodate oxidation of chitin, which demonstrates at the same time a novel approach for the preparation of
chitin nanocrystals (ChNCs). This oxidation is based on an unprecedented selective reaction of non-ordered domains of chitin by
the dimeric orthoperiodate ions (H₂I₂O₁₀⁴⁻) as the major species in
alkaline surroundings. Nearly 50 wt% of non-ordered regions are
dissolved after sequential accelerated partial deacetylation, periodate oxidation and β-alkoxy fragmentation, which allows the isolation of up to 50 wt% of uniform anisotropic zwitterionic ChNCs