6,302 research outputs found
The effect of on/off indicator design on state confusion, preference, and response time performance, executive summary
Investigated are five designs of software-based ON/OFF indicators in a hypothetical Space Station Power System monitoring task. The hardware equivalent of the indicators used in the present study is the traditional indicator light that illuminates an ON label or an OFF label. Coding methods used to represent the active state were reverse video, color, frame, check, or reverse video with check. Display background color was also varied. Subjects made judgments concerning the state of indicators that resulted in very low error rates and high percentages of agreement across indicator designs. Response time measures for each of the five indicator designs did not differ significantly, although subjects reported that color was the best communicator. The impact of these results on indicator design is discussed
Enhancing assertive community treatment with cognitive behavioral social skills training for schizophrenia: study protocol for a randomized controlled trial.
BackgroundSchizophrenia leads to profound disability in everyday functioning (e.g., difficulty finding and maintaining employment, housing, and personal relationships). Medications can effectively reduce positive symptoms (e.g., hallucinations and delusions), but they do not meaningfully improve daily life functioning. Psychosocial evidence-based practices (EBPs) improve functioning, but these EBPs are not available to most people with schizophrenia. The field must close the research and service delivery gap by adapting EBPs for schizophrenia to facilitate widespread implementation in community settings. Our hybrid effectiveness and implementation study represents an initiative to bridge this divide. In this study we will test whether an existing EBP (i.e., Cognitive Behavioral Social Skills Training (CBSST)) modified to work in practice settings (i.e., Assertive Community Treatment (ACT) teams) commonly available to persons with schizophrenia results in better consumer outcomes. We will also identify key factors relevant to developing future CBSST implementation strategies.Methods/designFor the effectiveness study component, persons with schizophrenia will be recruited from existing publicly funded ACT teams operating in community settings. Participants will be randomized to one of the 2 treatments (ACT alone or ACT + Adapted CBSST) and followed longitudinally for 18 months with assessments every 18 weeks after baseline (5 in total). The primary outcome domain is psychosocial functioning (e.g., everyday living skills and activities related to employment, education, and housing) as measured by self-report, testing, and observation. Additional outcome domains of interest include mediators of change in functioning, symptoms, and quality of services. Primary analyses will be conducted using linear mixed-effects models for continuous data. The implementation study component consists of a structured, mixed qualitative-quantitative methodology (i.e., Concept Mapping) to characterize and assess the implementation experience from multiple stakeholder perspectives in order to inform future implementation initiatives.DiscussionAdapting CBSST to fit into the ACT service delivery context found throughout the United States creates an opportunity to substantially increase the number of persons with schizophrenia who could have access to and benefit from EBPs. As part of the implementation learning process training materials and treatment workbooks have been revised to promote easier use of CBSST in the context of brief community-based ACT visits.Trial registrationClinicalTrials.gov NCT02254733 . Date of registration: 25 April 2014
The CFH Optical PDCS survey (COP) I: The Data
This paper presents and gives the COP (COP: CFHT Optical PDCS; CFHT:
Canada-France-Hawaii Telescope; PDCS: Palomar Distant Cluster Survey) survey
data. We describe our photometric and spectroscopic observations with the MOS
multi-slit spectrograph at the CFH telescope. A comparison of the photometry
from the PDCS (Postman et al. 1996) catalogs and from the new images we have
obtained at the CFH telescope shows that the different magnitude systems can be
cross-calibrated. After identification between the PDCS catalogues and our new
images, we built catalogues with redshift, coordinates and V, I and
Rmagnitudes. We have classified the galaxies along the lines of sight into
field and structure galaxies using a gap technique (Katgert et al. 1996). In
total we have observed 18 significant structures along the 10 lines of sight.Comment: 40 pages, 13 figures, accepted in A
Enhanced nasopharyngeal infection and shedding associated with an epidemic lineage of emm3 group A Streptococcus
Background:
A group A Streptococcus (GAS) lineage of genotype emm3, sequence type 15 (ST15) was
associated with a six month upsurge in invasive GAS disease in the UK. The epidemic lineage
(Lineage C) had lost two typical emm3 prophages, Ί315.1 and Ί315.2 associated with the
superantigen ssa, but gained a different prophage (ΊUK-M3.1) associated with a different
superantigen, speC and a DNAse spd1.
Methods and Results:
The presence of speC and spd1 in Lineage C ST15 strains enhanced both in vitro mitogenic
and DNAse activities over non-Lineage C ST15 strains. Invasive disease models in Galleria
mellonella and SPEC-sensitive transgenic mice, revealed no difference in overall invasiveness
of Lineage C ST15 strains compared to non-Lineage C ST15 strains, consistent with clinical
and epidemiological analysis. Lineage C strains did however markedly prolong murine nasal
infection with enhanced nasal and airborne shedding compared to non-Lineage C strains.
Deletion of speC or spd1 in two Lineage C strains identified a possible role for spd1 in airborne
shedding from the murine nasopharynx.
Conclusions:
Nasopharyngeal infection and shedding of Lineage C strains was enhanced compared to nonLineage
C strains and this was, in part, mediated by the gain of the DNase spd1 through prophage acquisition
On the equivalence of Eulerian and Lagrangian variables for the two-component Camassa-Holm system
The Camassa-Holm equation and its two-component Camassa-Holm system
generalization both experience wave breaking in finite time. To analyze this,
and to obtain solutions past wave breaking, it is common to reformulate the
original equation given in Eulerian coordinates, into a system of ordinary
differential equations in Lagrangian coordinates. It is of considerable
interest to study the stability of solutions and how this is manifested in
Eulerian and Lagrangian variables. We identify criteria of convergence, such
that convergence in Eulerian coordinates is equivalent to convergence in
Lagrangian coordinates. In addition, we show how one can approximate global
conservative solutions of the scalar Camassa-Holm equation by smooth solutions
of the two-component Camassa-Holm system that do not experience wave breaking
Anomalous oxygen isotope effect on the in-plane FIR conductivity of detwinned YBa2Cu3O
We observe an anomalous oxygen isotope effect on the a-axis component of the
far-infrared electronic response of detwinned YBa2Cu3O. For
O a pronounced low-energy electronic mode (LEM) appears around 240
cm. This a-axis LEM exhibits a clear aging effect, after one year it is
shifted to 190 cm. For O we cannot resolve a corresponding a-axis
LEM above 120 cm. We interpret the LEM in terms of a collective
electronic mode that is pinned by `isotopic defects', i.e. by the residual
O in the matrix of O.Comment: 10 pages, 2 figure
Solving One Dimensional Scalar Conservation Laws by Particle Management
We present a meshfree numerical solver for scalar conservation laws in one
space dimension. Points representing the solution are moved according to their
characteristic velocities. Particle interaction is resolved by purely local
particle management. Since no global remeshing is required, shocks stay sharp
and propagate at the correct speed, while rarefaction waves are created where
appropriate. The method is TVD, entropy decreasing, exactly conservative, and
has no numerical dissipation. Difficulties involving transonic points do not
occur, however inflection points of the flux function pose a slight challenge,
which can be overcome by a special treatment. Away from shocks the method is
second order accurate, while shocks are resolved with first order accuracy. A
postprocessing step can recover the second order accuracy. The method is
compared to CLAWPACK in test cases and is found to yield an increase in
accuracy for comparable resolutions.Comment: 15 pages, 6 figures. Submitted to proceedings of the Fourth
International Workshop Meshfree Methods for Partial Differential Equation
Usability and feasibility of consumer-facing technology to reduce unsafe medication use by older adults
Background
Mobile health technology can improve medication safety for older adults, for instance, by educating patients about the risks associated with anticholinergic medication use.
Objective
This study's objective was to test the usability and feasibility of Brain Buddy, a consumer-facing mobile health technology designed to inform and empower older adults to consider the risks and benefits of anticholinergics.
Methods
Twenty-three primary care patients aged â„60 years and using anticholinergic medications participated in summative, task-based usability testing of Brain Buddy. Self-report usability was assessed by the System Usability Scale and performance-based usability data were collected for each task through observation. A subset of 17 participants contributed data on feasibility, assessed by self-reported attitudes (feeling informed) and behaviors (speaking to a physician), with confirmation following a physician visit.
Results
Overall usability was acceptable or better, with 100% of participants completing each Brain Buddy task and a mean System Usability Scale score of 78.8, corresponding to âGoodâ to âExcellentâ usability. Observed usability issues included higher rates of errors, hesitations, and need for assistance on three tasks, particularly those requiring data entry. Among participants contributing to feasibility data, 100% felt better informed after using Brain Buddy and 94% planned to speak to their physician about their anticholinergic related risk. On follow-up, 82% reported having spoken to their physician, a rate independently confirmed by physicians.
Conclusion
Consumer-facing technology can be a low-cost, scalable intervention to improve older adultsâ medication safety, by informing and empowering patients. User-centered design and evaluation with demographically heterogeneous clinical samples uncovers correctable usability issues and confirms the value of interventions targeting consumers as agents in shared decision making and behavior change
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