Undoing the Factory Model: A Practical Field Test in Blended Learning

Merely, introducing new technologies into the classroom does little to address the needs of students–while it might create a welcome instructional environment for them, it does not address the compelling “elephant in the room.” Being able to orchestrate a student-centered, technology-rich lesson requires much expertise on the part of the teacher and a system-wide universally acknowledged educational technology plan. This study examines the paradigm shift required of teachers and the practical reality of adopting a blended learning environment to meet the needs of a diverse school district

Preparing Digital Natives to Teach: Time to Redesign Teacher Education Programs

Since the emergence of Marc Prensky\u27s concept of Digital Natives being taught by Digital Immigrants, education\u27s challenge has been to find a way to effectively teach those who have grown up in a net generation. Now that the first of these millenniel students are preparing to become teachers themselves, we have the opportunity, perhaps for the first time, to witness true digital natives teaching their own. This article will examine the paradigm shift required of teacher education programs if they are to prepare this digital teaching generation effectively for the educational challenge that lies ahead of them

Tools for educational innovation

How does an instructor keep abreast of educational technology changes and developments? What tools, apps and add-ins are available and how can they be used innovatively? This session will cover a variety of resources and tools that answer these two questions plus address how to pick the best tools for your instructional environment

Understanding the relationship between alcohol outlet density and life expectancy in Baltimore City: The role of community violence and community disadvantage

This research investigated the relationship between alcohol outlet density (AOD) and life expectancy, as mediated by community violence and community disadvantage. We used linear regression models to assess bivariate and multivariate relationships. There was a negative bivariate association between liquor store density and average life expectancy (β = â 7.3370, p < 0.001). This relationship was partially attenuated when controlling for community disadvantage and fully attenuated when controlling for community violence. Bars/taverns (i.e., onâ premise) were not associated with average life expectancy (β = â 0.589, p = 0.220). Liquor store density is associated with higher levels of community disadvantage and higher rates of violence, both of which are associated with lower life expectancies. Future research, potential intervention, and current related policies are discussed.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146620/1/jcop22099_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146620/2/jcop22099.pd

The XMM Cluster Survey: Forecasting cosmological and cluster scaling-relation parameter constraints

We forecast the constraints on the values of sigma_8, Omega_m, and cluster scaling relation parameters which we expect to obtain from the XMM Cluster Survey (XCS). We assume a flat Lambda-CDM Universe and perform a Monte Carlo Markov Chain analysis of the evolution of the number density of galaxy clusters that takes into account a detailed simulated selection function. Comparing our current observed number of clusters shows good agreement with predictions. We determine the expected degradation of the constraints as a result of self-calibrating the luminosity-temperature relation (with scatter), including temperature measurement errors, and relying on photometric methods for the estimation of galaxy cluster redshifts. We examine the effects of systematic errors in scaling relation and measurement error assumptions. Using only (T,z) self-calibration, we expect to measure Omega_m to +-0.03 (and Omega_Lambda to the same accuracy assuming flatness), and sigma_8 to +-0.05, also constraining the normalization and slope of the luminosity-temperature relation to +-6 and +-13 per cent (at 1sigma) respectively in the process. Self-calibration fails to jointly constrain the scatter and redshift evolution of the luminosity-temperature relation significantly. Additional archival and/or follow-up data will improve on this. We do not expect measurement errors or imperfect knowledge of their distribution to degrade constraints significantly. Scaling-relation systematics can easily lead to cosmological constraints 2sigma or more away from the fiducial model. Our treatment is the first exact treatment to this level of detail, and introduces a new `smoothed ML' estimate of expected constraints.Comment: 28 pages, 17 figures. Revised version, as accepted for publication in MNRAS. High-resolution figures available at http://xcs-home.org (under "Publications"

Early-type galaxies at z = 1.3. I. The Lynx supercluster: cluster and groups at z=1.3. Morphology and color-magnitude relation

We confirm the detection of 3 groups in the Lynx supercluster, at z~1.3, and give their redshifts and masses. We study the properties of the group galaxies as compared to the central clusters, RXJ0849+4452 and RXJ0848+4453, selecting 89 galaxies in the clusters and 74 galaxies in the groups. We morphologically classify galaxies by visual inspection, noting that our early-type galaxy (ETG) sample would have been contaminated at the 30% -40% level by simple automated classification methods (e.g. based on Sersic index). In luminosity selected samples, both clusters and groups show high fractions of Sa galaxies. The ETG fractions never rise above ~50% in the clusters, which is low compared to the fractions observed in clusters at z~1. However, ETG plus Sa fractions are similar to those observed for ETGs in clusters at z~1. Bulge-dominated galaxies visually classified as Sas might also be ETGs with tidal features or merger remnants. They are mainly red and passive, and span a large range in luminosity. Their star formation seems to have been quenched before experiencing a morphological transformation. Because their fraction is smaller at lower redshifts, they might be the spiral population that evolves into ETGs. For mass-selected samples, the ETG fraction show no significant evolution with respect to local clusters, suggesting that morphological transformations occur at lower masses and densities. The ETG mass-size relation shows evolution towards smaller sizes at higher redshift in both clusters and groups, while the late-type mass-size relation matches that observed locally. The group ETG red sequence shows lower zero points and larger scatters than in clusters, both expected to be an indication of a younger galaxy population. The estimated age difference is small when compared to the difference in age at different galaxy masses.Comment: ApJ, submitted - referee report answered - iterating with the refere

The 2022 monkeypox outbreak: A UK military perspective.

With the emergence of SARS-CoV-2 and now monkeypox, the UK Defence Medical Services have been required to provide rapid advice in the management of patients with airborne high consequence infectious diseases (A-HCID). The Defence Public Health Network (DPHN) cadre, consisting of closely aligned uniformed and civilian public health specialists have worked at pace to provide evidence-based recommendations on the clinical management, public health response and policy for monkeypox, with military medicine and pathology clinicians (primarily infectious disease physicians and medical microbiologists). Military environments can be complicated and nuanced requiring specialist input and advice to non-specialists as well as unit commanders both in the UK and overseas. DPHN and military infection clinicians have close links with the UK National Health Service (NHS) and the UK Health Security Agency (UKHSA), allowing for a dynamic two-way relationship that encompasses patient management, public health response, research and development of both UK military and national guidelines. This is further demonstrated with the Royal Air Force (RAF) Air Transport Isolator (ATI) capability, provided by Defence to support the UK Government and UKHSA. Military infectious disease clinicians are also embedded within NHS A-HCID units. In this manuscript we provide examples of the close interdisciplinary working of the DPHN and Defence clinicians in managing military monkeypox patients, co-ordinating the public health response, advising the Command and developing monkeypox policy for Defence through cross-government partnership. We also highlight the co-operation between civilian and military medical authorities in managing the current outbreak

The Dark Side of the Salad: Salmonella typhimurium Overcomes the Innate Immune Response of Arabidopsis thaliana and Shows an Endopathogenic Lifestyle

Salmonella enterica serovar typhimurium contaminated vegetables and fruits are considerable sources of human infections. Bacteria present in raw plant-derived nutrients cause salmonellosis, the world wide most spread food poisoning. This facultative endopathogen enters and replicates in host cells and actively suppresses host immune responses. Although Salmonella survives on plants, the underlying bacterial infection mechanisms are only poorly understood. In this report we investigated the possibility to use Arabidopsis thaliana as a genetically tractable host system to study Salmonella-plant interactions. Using green fluorescent protein (GFP) marked bacteria, we show here that Salmonella can infect various Arabidopsis tissues and proliferate in intracelullar cellular compartments. Salmonella infection of Arabidopsis cells can occur via intact shoot or root tissues resulting in wilting, chlorosis and eventually death of the infected organs. Arabidopsis reacts to Salmonella by inducing the activation of mitogen-activated protein kinase (MAPK) cascades and enhanced expression of pathogenesis related (PR) genes. The induction of defense responses fails in plants that are compromised in ethylene or jasmonic acid signaling or in the MKK3-MPK6 MAPK pathway. These findings demonstrate that Arabidopsis represents a true host system for Salmonella, offering unique possibilities to study the interaction of this human pathogen with plants at the molecular level for developing novel drug targets and addressing current safety issues in human nutrition

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

TESS Hunt for Young and Maturing Exoplanets (THYME) VII : Membership, rotation, and lithium in the young cluster Group-X and a new young exoplanet

The public, all-sky surveys Gaia and TESS provide the ability to identify new young associations and determine their ages. These associations enable study of planetary evolution by providing new opportunities to discover young exoplanets. A young association was recently identified by Tang et al. and F{\"u}rnkranz et al. using astrometry from Gaia (called "Group-X" by the former). In this work, we investigate the age and membership of this association; and we validate the exoplanet TOI 2048 b, which was identified to transit a young, late G dwarf in Group-X using photometry from TESS. We first identified new candidate members of Group-X using Gaia EDR3 data. To infer the age of the association, we measured rotation periods for candidate members using TESS data. The clear color--period sequence indicates that the association is the same age as the $300\pm50$ Myr-old NGC 3532. We obtained optical spectra for candidate members that show lithium absorption consistent with this young age. Further, we serendipitously identify a new, small association nearby Group-X, which we call MELANGE-2. Lastly, we statistically validate TOI 2048 b, which is $2.6\pm0.2$ \rearth\ radius planet on a 13.8-day orbit around its 300 Myr-old host star.Comment: Revised to correct error in reported planet radius (original: 2.1 Earth radii, corrected: 2.6 Earth radii) and units for planetary radius ratio entries in Table 8. All data tables available open-access with the AJ articl