9 research outputs found

    In trans early mosaic mutational escape and novel phenotypic features of germline SAMD9 mutation

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    Beach safety: Can drones provide a platform for sighting sharks?

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    CSIRO 2019 Open Access. Context: A series of unprovoked shark attacks on New South Wales (Australia) beaches between 2013 and 2015 triggered an investigation of new and emerging technologies for protecting bathers. Traditionally, bather protection has included several methods for shark capture, detection and/or deterrence but has often relied on environmentally damaging techniques. Heightened environmental awareness, including the important role of sharks in the marine ecosystem, demands new techniques for protection from shark attack. Recent advances in drone-related technologies have enabled the possibility of real-time shark detection and alerting. Aim: To determine the reliability of drones to detect shark analogues in the water across a range of environmental conditions experienced on New South Wales beaches. Methods: A standard multirotor drone (DJI Inspire 1) was used to detect shark analogues as a proxy during flights at 0900, 1200 and 1500 hours over a 3-week period. The 27 flights encompassed a range of environmental conditions, including wind speed (2-30.0 km h-1), turbidity (0.4-6.4 m), cloud cover (0-100%), glare (0-100%), seas (0.4-1.4 m), swells (1.4-2.5 m) and sea state (Beaufort Scale 1-5 Bf). Key results: Detection rates of the shark analogues over the 27 flights were significantly higher for the independent observer conducting post-flight video analysis (50%) than for the drone pilot (38%) (Wald P = 0.04). Water depth and turbidity significantly impaired detection of analogues (Wald P = 0.04). Specifically, at a set depth of 2 m below the water surface, very few analogues were seen by the observer or pilot when water turbidity reduced visibility to less than 1.5 m. Similarly, when water visibility was greater than 1.5 m, the detection rate was negatively related to water depth. Conclusions: The present study demonstrates that drones can fly under most environmental conditions and would be a cost-effective bather protection tool for a range of user groups. Implications: The most effective use of drones would occur during light winds and in shallow clear water. Although poor water visibility may restrict detection, sharks spend large amounts of time near the surface, therefore providing a practical tool for detection in most conditions

    PHENIX muon arms

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    PHENIX detector overview

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    Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study

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    Background Stratifying risk of postoperative pulmonary complications after major abdominal surgery allows clinicians to modify risk through targeted interventions and enhanced monitoring. In this study, we aimed to identify and validate prognostic models against a new consensus definition of postoperative pulmonary complications. Methods We did a systematic review and international external validation cohort study. The systematic review was done in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched MEDLINE and Embase on March 1, 2020, for articles published in English that reported on risk prediction models for postoperative pulmonary complications following abdominal surgery. External validation of existing models was done within a prospective international cohort study of adult patients (≥18 years) undergoing major abdominal surgery. Data were collected between Jan 1, 2019, and April 30, 2019, in the UK, Ireland, and Australia. Discriminative ability and prognostic accuracy summary statistics were compared between models for the 30-day postoperative pulmonary complication rate as defined by the Standardised Endpoints in Perioperative Medicine Core Outcome Measures in Perioperative and Anaesthetic Care (StEP-COMPAC). Model performance was compared using the area under the receiver operating characteristic curve (AUROCC). Findings In total, we identified 2903 records from our literature search; of which, 2514 (86·6%) unique records were screened, 121 (4·8%) of 2514 full texts were assessed for eligibility, and 29 unique prognostic models were identified. Nine (31·0%) of 29 models had score development reported only, 19 (65·5%) had undergone internal validation, and only four (13·8%) had been externally validated. Data to validate six eligible models were collected in the international external validation cohort study. Data from 11 591 patients were available, with an overall postoperative pulmonary complication rate of 7·8% (n=903). None of the six models showed good discrimination (defined as AUROCC ≥0·70) for identifying postoperative pulmonary complications, with the Assess Respiratory Risk in Surgical Patients in Catalonia score showing the best discrimination (AUROCC 0·700 [95% CI 0·683–0·717]). Interpretation In the pre-COVID-19 pandemic data, variability in the risk of pulmonary complications (StEP-COMPAC definition) following major abdominal surgery was poorly described by existing prognostication tools. To improve surgical safety during the COVID-19 pandemic recovery and beyond, novel risk stratification tools are required. Funding British Journal of Surgery Society

    PHENIX detector overview

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    The PHENIX detector is designed to perform a broad study of A-A, p-A, and p-p collisions to investigate nuclear matter under extreme conditions. A wide variety of probes, sensitive to all timescales, are used to study systematic variations with species and energy as well as to measure the spin structure of the nucleon. Designing for the needs of the heavy-ion and polarized-proton programs has produced a detector with unparalleled capabilities. PHENIX measures electron and muon pairs, photons, and hadrons with excellent energy and momentum resolution. The detector consists of a large number of subsystems that are discussed in other papers in this volume. The overall design parameters of the detector are presented. (C) 2002 Elsevier Science B.V. All rights reserved

    PHENIX detector overview

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