619 research outputs found
Business Activity in South Dakota, 1915 - 1938
The index of business activity shown in the accompanying charts and table represents a preliminary study of the fluctuations and growth of industry and trade in South Dakota. It is anticipated that the study will be continued and expanded until it includes as adequate a statistical presentation of the cyclical changes in the economic situation in the State as is now available for the United States as a whole
Before the West Was West
Before the West Was West examines the extent to which scholars have engaged in-depth with pre-1800 “western” texts and asks what we mean by “western” American literature in the first place and when that designation originated.
Calling into question the implicit temporal boundaries of the “American West” in literature, a literature often viewed as having commenced only at the beginning of the 1800s, Before the West Was West explores the concrete, meaningful connections between different texts as well as the development of national ideologies and mythologies. Examining pre-nineteenth-century writings that do not fit conceptions of the Wild West or of cowboys, cattle ranching, and the Pony Express, these thirteen essays demonstrate that no single, unified idea or geography defines the American West.
Contributors investigate texts ranging from the Norse Vinland Sagas and Mary Rowlandson’s famous captivity narrative to early Spanish and French exploration narratives, an eighteenth-century English novel, and a play by Aphra Behn. Through its examination of the disparate and multifaceted body of literature that arises from a broad array of cultural backgrounds and influences,Before the West Was West apprehends the literary West in temporal as well as spatial and cultural terms and poses new questions about “westernness” and its literary representation
National BSUG audit of stress urinary incontinence surgery in England
Introduction and hypothesis
The aim of the British Society of Urogynaecology (BSUG) 2013 audit for stress urinary incontinence (SUI) surgery was to conduct a national clinical audit looking at the intra- and postoperative complications and provide outcomes for these procedures. This audit was supported by the Healthcare Quality Improvement Partnership (HQIP) and National Health Service (NHS) England.
Methods
Data were collected for all continence procedures performed in 2013 through the BSUG database. All clinicians in England performing SUI surgery were invited to submit data to a central database. Outcomes data for the different continence procedures were collected and included intraoperative and postoperative complications and the change in continence scores at postoperative follow-up Changing trends in stress incontinence surgery were also assessed.
Results
We recorded 4993 urinary incontinence procedures from 177 consultants at 110 centres in England: 94.6% were midurethral slings; 86.7% (4331) were submitted by BSUG members with the remaining 13.3% submitted by non-BSUG members. Postoperative follow-up data were available for 3983 (80%) patients: 92.3% (3676) were very much better/much better postoperatively, and 4806 (96.3%) proceeded with no reported complications. There were 187 cases (3.7%) in which a perioperative complication was recorded. Pain persisting >30 days was reported in 1.9% of all patients.
Conclusions
Surgery for SUI has good outcomes in the short term. Midurethral synthetic slings have been shown to be safe and effective as a treatment option, with >90% being very much/much better at their postoperative follow-up
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Abnormal rib count in scoliosis surgery: impact on the reporting of spinal fusion levels
Purpose Variation in rib numbering has been noted in adolescent idiopathic scoliosis (AIS), but its effect on the reporting of fusion levels has not been studied. We hypothesized that vertebral numbering variations can lead to differing documentation of fusion levels. Methods: We examined the radiographs of 161 surgical AIS patients and 179 control patients without scoliosis. For AIS patients, the operative report of fusion levels was compared to conventional vertebral labeling from the first thoracic level and proceeding caudal. We defined normal counts as 12 thoracic (rib-bearing) and five lumbar (non-rib-bearing) vertebrae. We compared our counts with data from 181 anatomic specimens. Results: Among AIS patients, 22 (14 %) had an abnormal number of ribs and 29 (18 %) had either abnormal rib or lumbar count. In 12/29 (41 %) patients, the operative report differed from conventional labeling by one level, versus 3/132 (2 %) patients with normal numbering (p < 0.001). However, there were no cases seen of wrong fusion levels based on curve pattern. Among controls, 11 % had abnormal rib count (p = 0.41) compared to the rate in AIS. Anatomic specimen data did not differ in abnormal rib count (p = 1.0) or thoracolumbar pattern (p = 0.59). Conclusions: The rate of numerical variations in the thoracolumbar vertebrae of AIS patients is equivalent to that in the general population. When variations in rib count are present, differences in numbering levels can occur. In the treatment of scoliosis, no wrong fusion levels were noted. However, for both scoliosis patients and the general population, we suggest adherence to conventional labeling to enhance clarity
Experimental Charging Behavior of Orion UltraFlex Array Designs
The present ground based investigations give the first definitive look describing the charging behavior of Orion UltraFlex arrays in both the Low Earth Orbital (LEO) and geosynchronous (GEO) environments. Note the LEO charging environment also applies to the International Space Station (ISS). The GEO charging environment includes the bounding case for all lunar mission environments. The UltraFlex photovoltaic array technology is targeted to become the sole power system for life support and on-orbit power for the manned Orion Crew Exploration Vehicle (CEV). The purpose of the experimental tests is to gain an understanding of the complex charging behavior to answer some of the basic performance and survivability issues to ascertain if a single UltraFlex array design will be able to cope with the projected worst case LEO and GEO charging environments. Stage 1 LEO plasma testing revealed that all four arrays successfully passed arc threshold bias tests down to -240 V. Stage 2 GEO electron gun charging tests revealed that only the front side area of indium tin oxide coated array designs successfully passed the arc frequency test
Experimental Tests of UltraFlex Array Designs in Low Earth Orbital and Geosynchronous Charging Environments
The present ground based investigations give the first definitive look describing the expected on-orbit charging behavior of Orion UltraFlex array coupons in the Low Earth Orbital and Geosynchronous Environments. Furthermore, it is important to note that the LEO charging environment also applies to the International Space Station as well as to the lunar mission charging environments. The GEO charging environment includes the bounding case for all lunar orbital and lunar surface mission environments. The UltraFlex thin film photovoltaic array technology has been targeted to become the sole power system for life support and on-orbit power for the manned Aires Crew Exploration Vehicle. It is therefore, crucial to gain an understanding of the complex charging behavior to answer some of the basic performance and survivability issues in an attempt to ascertain that a single UltraFlex array design will be able to cope with the projected worst case LEO and GEO charging environments. Testing was limited to four array coupons, two coupons each from two different array manufactures, Emcore and Spectrolab. The layout of each array design is identical and varies only in the actual cell technology used. The individual array cells from each manufacturer have an antireflection layered coating and come in two different varieties either uncoated (only AR coating) or coated with a thin conducting ITO layer. The LEO Plasma tests revealed that all four coupons passed the arc threshold -120 V bias tests. GEO electron gun charging tests revealed that only front side area of ITO coated coupons passed tests. Only the Emcore AR array passed backside Stage 2 GEO Tests
Thruster Plume Plasma Diagnostics: A Ground Chamber Experiment for a 2-Kilowatt Arcjet
Although detailed near field (0 to 3 cm) information regarding the exhaust plume of a two kilowatt arc jet is available (refs. 1 to 6), there is virtually little or no information (outside of theoretical extrapolations) available concerning the far field (2.6 to 6.1 m). Furthermore real information about the plasma at distances between (3 to 6 m) is of critical importance to high technology satellite companies in understanding the effect of arc jet plume exhausts on space based power systems. It is therefore of utmost importance that one understands the exact nature of the interaction between the arc jet plume, the spacecraft power system and the surrounding electrical plasma environment. A good first step in understanding the nature of the interactions lies in making the needed plume parameter measurements in the far field. All diagnostic measurements are performed inside a large vacuum system (12 m diameter by 18 m high) with a full scale arc jet and solar array panel in the required flight configuration geometry. Thus, necessary information regarding the plume plasma parameters in the far field is obtained. Measurements of the floating potential, the plasma potential, the electron temperature, number density, density distribution, debye length, and plasma frequency are obtained at various locations about the array (at vertical distances from the arc jet nozzle: 2.6, 2.7, 2.8, 3.2, 3.6, 4.0, 4.9, 5.0, 5.4, 5.75, and 6.14 m). Plasma diagnostic parameters are measured for both the floating and grounded configurations of the arc jet anode and array. Spectroscopic optical measurements are then acquired in close proximity to the nozzle, and contamination measurements are made in the vicinity of the array utilizing a mass spectrometer and two Quartz Crystal Microbalances (QCM's)
17β-Estradiol Potentiates the Reinstatement of Cocaine Seeking in Female Rats: Role of the Prelimbic Prefrontal Cortex and Cannabinoid Type-1 Receptors
Clinical observations imply that female cocaine addicts experience enhanced relapse vulnerability compared with males, an effect tied to elevated estrogen phases of the ovarian hormone cycle. Although estrogens can enhance drug-seeking behavior, they do not directly induce reinstatement on their own. To model this phenomenon, we tested whether an estrogen could augment drug-seeking behavior in response to an ordinarily subthreshold reinstatement trigger. Following cocaine self-administration and extinction, female rats were ovariectomized to isolate estrogen effects on reinstatement. Although neither peak proestrus levels of the primary estrogen 17β-estradiol (E2; 10 μg/kg, i.p., 1-h pretreatment) nor a subthreshold cocaine dose (1.25 mg/kg, i.p.) alone were sufficient to reinstate drug-seeking behavior, pretreatment with E2 potentiated reinstatement to the ordinarily subthreshold cocaine dose. Furthermore, E2 microinfusions revealed that E2 (5 μg/0.3 μl, 15-min pretreatment) acts directly within the prelimbic prefrontal cortex (PrL-PFC) to potentiate reinstatement. As E2 has been implicated in endocannabinoid mobilization, which can disinhibit PrL-PFC projection neurons, we investigated whether cannabinoid type-1 receptor (CB1R) activation is necessary for E2 to potentiate reinstatement. The CB1R antagonist AM251 (1 or 3 mg/kg, i.p., 30-min pretreatment) administered prior to E2 and cocaine suppressed reinstatement in a dose-dependent manner. Finally, PrL-PFC AM251 microinfusions (300 ng/side, 15-min pretreatment) also suppressed E2-potentiated reinstatement. Together, these results suggest that E2 can augment reactivity to an ordinarily subthreshold relapse trigger in a PrL-PFC CB1R activation-dependent manner
Information Transmission and the Oral Tradition: Evidence of a Late-Life Service Niche for Tsimane Amerindians
Storytelling can affect wellbeing and fitness by transmitting information and reinforcing cultural codes of conduct. Despite their potential importance, the development and timing of storytelling skills, and the transmission of story knowledge have received minimal attention in studies of subsistence societies that more often focus on food production skills. Here we examine how storytelling and patterns of information transmission among Tsimane forager-horticulturalists are predicted by the changing age profiles of storytellers’ abilities and accumulated experience. We find that storytelling skills are most developed among older adults who demonstrate superior knowledge of traditional stories and who report telling stories most. We find that the important information transmitted via storytelling typically flows from older to younger generations, and stories are primarily learned from older same-sex relatives, especially grandparents. Our findings suggest that the oral tradition provides a specialized late-life service niche for Tsimane adults who have accumulated important experience and knowledge relevant to foraging and sociality, but have lost comparative advantage in other productive domains. These findings may help extend our understanding of the evolved human life history by illustrating how changes in embodied capital predict the development of information transmission services in a forager-horticulturalist economy
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