1,176 research outputs found
Time dependence studies on giant magnetoresistive Co/Cu multilayers
Time dependence studies consisting of applying current
steps at fixed applied fields have been carried out on bilinear and biquadratic giant magnetoresistive (GMR) Co/Cu multilayers in a temperature controlled environment. It has been shown that the voltage responses to current steps of these aged multilayers are greater in magnitude before field cycling compared to those made after field cycling. Normalized voltage measurements for
some samples suggest a magnetic viscosity effect due to a current step at zero-field is present and before field cycling. The effect is reduced after field cycling. This behavior suggests that the effect being seen is purely magnetic in origin, as only the field is being
varied. A ln( ) type function has been curve fitted to the zero field voltage response to a current step before field cycling. Voltage measurements made on the Co/Cu films at different field values show that as the applied fields are increased the voltage response has a reduced ln(t) character
Oxygen consumption in ammocoetes of the lamprey Ichthyomyzon hubbsi Raney
1. A continuous flow respirometer suitable for measuring oxygen consumption in some small burrowing aquatic animals is described.
2. Rates of oxygen consumption in ammocoetes of the lamprey Ichthyomyzon hubbsi are low, with mean values at 15.5 °C ranging from 38.8 to 97.1 µl/g/h for large (3.44 g) and small (0.14 g) animals respectively.
3. A Q10 of 3.6 was found for medium-size animals (1.18 g) between 3.5 and 22.5 °C.
4. The slope of the logarithmic linear regression relating weight and oxygen consumption was 0.718 at 15.5°C.
5. The rates of oxygen consumption are discussed with respect to the ecology of ammocoetes and compared with those obtained for other lower vertebrates
Biology of Hymenosoma orbiculare Desm in Lake Sibaya
Hymenosoma orbiculare, (Crustacea: Brachyura: Hymenosomatidae) a crab common in estuaries in south- and south east Africa occurs in freshwater in Lake Sibaya at depths down to 40 m. This is the only known freshwater record of this species. The population density in the lake is fairly uniform declining in shallow and very deep water with an a11erage- of 2,5 m-2 (134 Jm-2). The proportion of females in the population increases with depth. Females carry fewer eggs than estuarine populations and breeding appears to occur throughout the year. Both zoeae and adults differ morphologically from estuarine populations. These differences in breeding, biology and morphology raise the possibility that the Lake Sibaya population is specifically distinct from estuarine populations and this is discussed in relation to other instances of hymenosomatid invasion of freshwater habitats.Hymenosoma orbiculare, (Crustacea: Brachyura: Hymenosomatidae) 'n krap wat algemeen voorkom in riviermondings in suid en suidoos Afrika, word ook aangetref in die varswater van die Sibayameer tot op 'n diepte van 40 m. Dit is die enigste bekende geval van hierdie spesie se voorkoms in varswater. Die populasiedigtheid is redelik eenvormig en neem af vanaf vlak tot baie diep water met 'n gemiddeld van 2,5 m-2 (134 Jm -2). Die verhouding van wyfies tot mannetjies neem toe met toename in diepte. Wyfies dra minder eiers as die in riviermondings en voortplanting vind blykbaar dwarsdeur die jaar plaas. Seide die zoeae en volwassenes verskil morfologies van die in riviermondings. Hierdie verskille in teling, biologie en morfologie dui op 'n moontlike spesieverskil tussen die bevolking in die Sibayameer en die in riviermondings. Hierdie aspekte word bespreek in die lig van ander gevalle van toetreding tot varswaterhabitatte onder die Hymenosomatidae
5,6-dihydroxyindole-2-carboxylic acid (DHICA): a First Principles Density-Functional Study
We report first principles density functional calculations for
5,6-dihydroxyindole-2-carboxylic acid (DHICA) and several reduced forms. DHICA
and 5,6-dihydroxyindole (DHI) are believed to be the basic building blocks of
the eumelanins. Our results show that carboxylation has a significant effect on
the physical properties of the molecules. In particular, the relative
stabilities and the HOMO-LUMO gaps (calculated with the SCF method) of
the various redox forms are strongly affected. We predict that, in contrast to
DHI, the density of unpaired electrons, and hence the ESR signal, in DHICA is
negligibly small.Comment: 5 pages, 2 figure
Restricted three body problems at the nanoscale
In this paper, we investigate some of the classical restricted three body
problems at the nanoscale, such as the circular planar restricted problem for
three C60 fullerenes, and a carbon atom and two C60 fullerenes. We model the
van der Waals forces between the fullerenes by the Lennard-Jones potential. In
particular, the pairwise potential energies between the carbon atoms on the
fullerenes are approximated by the continuous approach, so that the total
molecular energy between two fullerenes can be determined analytically. Since
we assume that such interactions between the molecules occur at sufficiently
large distance, the classical three body problems analysis is legitimate to
determine the collective angular velocity of the two and three C60 fullerenes
at the nanoscale. We find that the maximum angular frequency of the two and
three fullerenes systems reach the terahertz range and we determine the
stationary points and the points which have maximum velocity for the carbon
atom for the carbon atom and the two fullerenes system
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Cannabidivarin is anticonvulsant in mouse and rat in vitro and in seizure models
Summary
Background and purpose: Phytocannabinoids in Cannabis sativa have diverse
pharmacological targets extending beyond cannabinoid receptors and several exert notable
anticonvulsant effects. For the first time, we investigated the anticonvulsant profile of the
phytocannabinoid cannabidivarin (CBDV) in vitro and in in vivo seizure models.
Experimental approach: The effect of CBDV (1-100μM) on epileptiform local field
potentials (LFPs) induced in rat hippocampal brain slices by 4-AP application or Mg2+-free
conditions was assessed by in vitro multi-electrode array recordings. Additionally, the
anticonvulsant profile of CBDV (50-200 mg kg-1) in vivo was investigated in four rodent
seizure models: maximal electroshock (mES) and audiogenic seizures in mice, and
pentylenetetrazole (PTZ) and pilocarpine-induced seizures in rat. CBDV effects in
combination with commonly-used antiepileptic drugs were investigated in rat seizures.
Finally, the motor side effect profile of CBDV was investigated using static beam and gripstrength
assays.
Key results: CDBV significantly attenuated status epilepticus-like epileptiform LFPs
induced by 4-AP and Mg2+-free conditions. CBDV had significant anticonvulsant effects in
mES (≥100 mg kg-1), audiogenic (≥50 mg kg-1) and PTZ-induced seizures (≥100 mg kg-1).
CBDV alone had no effect against pilocarpine-induced seizures, but significantly attenuated
these seizures when administered with valproate or phenobarbital at 200 mg kg-1 CBDV.
CBDV had no effect on motor function.
Conclusions and Implications: These results indicate that CBDV is an effective
anticonvulsant across a broad range of seizure models, does not significantly affect normal
motor function and therefore merits further investigation in chronic epilepsy models to justify
human trials
Constraints on diffuse neutrino background from primordial black holes
We calculated the energy spectra and the fluxes of electron neutrino emitted
in the process of evaporation of primordial black holes (PBHs) in the early
universe. It was assumed that PBHs are formed by a blue power-law spectrum of
primordial density fluctuations. We obtained the bounds on the spectral index
of density fluctuations assuming validity of the standard picture of
gravitational collapse and using the available data of several experiments with
atmospheric and solar neutrinos. The comparison of our results with the
previous constraints (which had been obtained using diffuse photon background
data) shows that such bounds are quite sensitive to an assumed form of the
initial PBH mass function.Comment: 18 pages,(with 7 figures
Western oceanus procellarum as seen by c1xs on chandrayaan-1
We present the analysis of an X-ray fluorescence (XRF) observation of the western part of Oceanus Procellarum on the Moon’s nearside made by the Chandrayaan-1 X-ray Spectrometer on 10th February 2009. Through forward modelling of the X-ray spectra, we provide estimates of the MgO/SiO2 and Al2O3/SiO2 ratios for seven regions along the flare’s ground track. These results are combined with FeO and TiO2 contents derived from Clementine multispectral reflectance data in order to investigate the compositional diversity of this region of the Moon. The ground track observed consists mainly of low-Ti basaltic units, and the XRF data are largely consistent with this expectation. However, we obtain higher Al2O3/SiO2 ratios for these units than for most basalts in the Apollo sample collection. The widest compositional variation between the different lava flows is in wt% FeO content. A footprint that occurs in a predominantly highland region, immediately to the north of Oceanus Procellarum, has a composition that is consistent with mixing between low-Ti mare basaltic and more feldspathic regoliths. In contrast to some previous studies, we find no evidence for systematic differences in surface composition, as determined through X-ray and gamma-ray spectroscopy techniques
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