128 research outputs found
Signature whistle productions, development, and perception in free-ranging bottlenose dolphins
Data from behavioral observations and acoustic recordings of free-ranging
bottlenose dolphins (Tursiops truncatus) were analyzed to determine whether signature
whistles occur in the wild, and to determine when whistle crystallization occurs in calves.
The study animals were part of a resident community of bottlenose dolphins in the waters
near Sarasota, Florida. Three mother-calf pairs and their associates were recorded for a
total of 141.25 hours between May and August of 1994 and 1995. Each whistle was
conservatively classified into one of four categories: signature, probable signature,
upsweep, or other. Overall whistle production varied significantly with both activity and
group size. Whistles occurred more frequently than expected during socializing and in
groups of over five dolphins, and occurred less frequently than expected during travelling
and in groups of two dolphins. Signature and probable signature whistles made up
approximately 52% of all whistles produced by these free-ranging bottlenose dolphins.
Each of the three calves studied developed its whistle prior to four months of age.
Each mother’s signature whistle comprised approximately 3% of the whistles recorded
during the first year of her calf’s life, regardless of social or auditory environment, which
varied greatly among the calves. One calf developed a signature whistle similar to that of
its mother.
To evaluate whether certain acoustic features of whistles are perceptually
important to dolphins, 44 playback experiments were conducted with temporarily
captured dolphins near Sarasota, Florida in June of 2000 and 2001. Response measures
included number of head turns toward or away from the speaker, echolocation bouts, and
whistles. In a modified habituation-dishabituation design, habituation to the first stimulus did not occur. Additionally, there were low overall response rates to most synthetic
stimuli. There were no significant differences in responses to whistles containing
differing numbers of loops or differing contours, with the exception that head turn rates
were higher in response to modified synthetic upsweeps than to several other synthetic
stimuli. In addition, whistle response rates were significantly higher to known, natural
whistle stimuli than to synthetic upsweeps. These results suggest that natural whistles and
modified upsweeps contain whistle features not adequately conveyed by other synthetic
stimuli
Connecting the study of wild influenza with the potential for pandemic disease
Continuing outbreaks of pathogenic (H5N1) and pandemic (SOIVH1N1) influenza have underscored the need to understand the origin, characteristics, and evolution of novel influenza A virus (IAV) variants that pose a threat to human health. In the last 4–5 years, focus has been placed on the organization of large-scale surveillance programs to examine the phylogenetics of avian influenza virus (AIV) and host–virus relationships in domestic and wild animals. Here we review the current gaps in wild animal and environmental surveillance and the current understanding of genetic signatures in potentially pandemic strains.National Institute of Allergy and Infectious Diseases (U.S.) (Contract HHSN266200700010C)Massachusetts Institute of Technolog
Sheep Updates 2006 - part 3
This session covers six papers from different authors:
GRAZING
1. Making better use of clover, Karen Venning and Andrew Thompson, Department of Primary Industries, Victoria
2. Grazing systems demonstration to optimise pasture utilisation and stocking rate, Mike Hyder, Sue-Ellen Shaw, Kelly Hill and Ron McTaggart, Department of Agriculture and Food Western Australia.
3. Know your audience to increase their rate of practice change - Lifetime Wool as an example, Gus Rose, Department of Agriculture and Food Western Australia, Carolyn Kabore, Kazresearch
REPRODUCTION
4. Lifetime Wool - Ewe Management Guidlines, Mandy Curnow, Department of Agriculture and Food Western Australia
5. Achieving the best reproductive performance from your hoggets, Kenyon PR, Morris ST, West DM, Perkins NR, Pinchbeck GL., Institute of Veterinary, Animal and Biomedical Sciences, Massey University, New Zealand.
6. Lifetime Wool: Twin futures, Dr Ralph Behrendt, Department of Primary Industries, Victori
Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients.
Naturally acquired blood-stage infections of the malaria parasite Plasmodium falciparum typically harbour multiple haploid clones. The apparent number of clones observed in any single infection depends on the diversity of the polymorphic markers used for the analysis, and the relative abundance of rare clones, which frequently fail to be detected among PCR products derived from numerically dominant clones. However, minority clones are of clinical interest as they may harbour genes conferring drug resistance, leading to enhanced survival after treatment and the possibility of subsequent therapeutic failure. We deployed new generation sequencing to derive genome data for five non-propagated parasite isolates taken directly from 4 different patients treated for clinical malaria in a UK hospital. Analysis of depth of coverage and length of sequence intervals between paired reads identified both previously described and novel gene deletions and amplifications. Full-length sequence data was extracted for 6 loci considered to be under selection by antimalarial drugs, and both known and previously unknown amino acid substitutions were identified. Full mitochondrial genomes were extracted from the sequencing data for each isolate, and these are compared against a panel of polymorphic sites derived from published or unpublished but publicly available data. Finally, genome-wide analysis of clone multiplicity was performed, and the number of infecting parasite clones estimated for each isolate. Each patient harboured at least 3 clones of P. falciparum by this analysis, consistent with results obtained with conventional PCR analysis of polymorphic merozoite antigen loci. We conclude that genome sequencing of peripheral blood P. falciparum taken directly from malaria patients provides high quality data useful for drug resistance studies, genomic structural analyses and population genetics, and also robustly represents clonal multiplicity
Recommended from our members
"Older Adults with ASD: The Consequences of Aging." Insights from a series of special interest group meetings held at the International Society for Autism Research 2016-2017
A special interest group (SIG) entitled "Older Adults with ASD: The Consequences of Aging" was held at the International Society for Autism Research (INSAR) annual meetings in 2016 and 2017. The SIG and subsequent meetings brought together, for the first time, international delegates who were members of the autistic community, researchers, practitioners and service providers. Based on aging autism research that is already underway in UK, Europe, Australia and North America, discussions focussed on conceptualising the parameters of aging when referring to autism, and the measures that are appropriate to use with older adults when considering diagnostic assessment, cognitive factors and quality of life in older age. Thus, the aim of this SIG was to progress the research agenda on current and future directions for autism research in the context of aging. A global issue on how to define 'aging' when referring to ASD was at the forefront of discussions. The ‘aging’ concept can in principle refer to all developmental transitions. However, in this paper we focus on the cognitive and physical changes that take place from mid-life onwards. Accordingly, it was agreed that aging and ASD research should focus on adults over the age of 50 years, given the high rates of co-occurring physical and mental health concerns and increased risk of premature death in some individuals. Moreover, very little is known about the cognitive change, care needs and outcomes of autistic adults beyond this age. Discussions on the topics of diagnostic and cognitive assessments, and of quality of life and well-being were explored through shared knowledge about which measures are currently being used and which background questions should be asked to obtain comprehensive and informative developmental and medical histories. Accordingly, a survey was completed by SIG delegates who were representatives of international research groups across four continents, and who are currently conducting studies with older autistic adults. Considerable overlap was identified across different research groups in measures of both autism and quality of life, which pointed to combining data and shared learnings as the logical next step. Regarding the background questions that were asked, the different research groups covered similar topics but the groups differed in the way these questions were formulated when working with autistic adults across a range of cognitive abilities. It became clear that continued input from individuals on the autism spectrum is important to ensure that questionnaires used in ongoing and future are accessible and understandable for people across the whole autistic spectrum, including those with limited verbal abilities
Gender equality, resilience to climate change, and the design of livestock projects for rural livelihoods
Currently, there is growing interest in how livestock projects can contribute to resilience
to the effects of climate change. In this article we recommend a shift away from gross
productivity to sustainability, via the use of thrifty local breeds, with an additional
emphasis on improving survival of young animals. These animals, due to their local
adaptations, are more likely to be resilient to climate change. There is a gender
dimension to these proposals, since smaller animals and local breeds are more likely to
be perceived by communities as suitable for husbandry by women. We recommend a
re-orientation towards an explicit gender-equality focus for these projects
Quantitative Measurements of Alternating Finger Tapping in Parkinson's Disease Correlate With UPDRS Motor Disability and Reveal the Improvement in Fine Motor Control From Medication and Deep Brain Stimulation
Abstract: The Unified Parkinson's Disease Rating Scale (UP-DRS) is the primary outcome measure in most clinical trials of Parkinson's disease (PD) therapeutics. Each subscore of the motor section (UPDRS III) compresses a wide range of motor performance into a coarse-grained scale from 0 to 4; the assessment of performance can also be subjective. Quantitative digitography (QDG) is an objective, quantitative assessment of digital motor control using a computer-interfaced musical keyboard. In this study, we show that the kinematics of a repetitive alternating finger-tapping (RAFT) task using QDG correlate with the UPDRS motor score, particularly with the bradykinesia subscore, in 33 patients with PD. We show that dopaminergic medication and an average of 9.5 months of bilateral subthalamic nucleus deep brain stimulation (B-STN DBS) significantly improve UPDRS and QDG scores but may have different effects on certain kinematic parameters. This study substantiates the use of QDG to measure motor outcome in trials of PD therapeutics and shows that medication and B-STN DBS both improve fine motor control
Hearing Loss in Stranded Odontocete Dolphins and Whales
The causes of dolphin and whale stranding can often be difficult to determine. Because toothed whales rely on echolocation for orientation and feeding, hearing deficits could lead to stranding. We report on the results of auditory evoked potential measurements from eight species of odontocete cetaceans that were found stranded or severely entangled in fishing gear during the period 2004 through 2009. Approximately 57% of the bottlenose dolphins and 36% of the rough-toothed dolphins had significant hearing deficits with a reduction in sensitivity equivalent to severe (70–90 dB) or profound (>90 dB) hearing loss in humans. The only stranded short-finned pilot whale examined had profound hearing loss. No impairments were detected in seven Risso's dolphins from three different stranding events, two pygmy killer whales, one Atlantic spotted dolphin, one spinner dolphin, or a juvenile Gervais' beaked whale. Hearing impairment could play a significant role in some cetacean stranding events, and the hearing of all cetaceans in rehabilitation should be tested
- …