Antegrade common femoral artery closure device use is associated with decreased complications.

ObjectiveAntegrade femoral artery access is often used for ipsilateral infrainguinal peripheral vascular intervention. However, the use of closure devices (CD) for antegrade access (AA) is still considered outside the instructions for use for most devices. We hypothesized that CD use for antegrade femoral access would not be associated with an increased odds of access site complications.MethodsThe Vascular Quality Initiative was queried from 2010 to 2019 for infrainguinal peripheral vascular interventions performed via femoral AA. Patients who had a cutdown or multiple access sites were excluded. Cases were then stratified into whether a CD was used or not. Hierarchical multivariable logistic regressions controlling for hospital-level variation were used to examine the independent association between CD use and access site complications. A sensitivity analysis using coarsened exact matching was performed using factors different between treatment groups to reduce imbalance between the groups.ResultsOverall, 11,562 cases were identified and 5693 (49.2%) used a CD. Patients treated with a CD were less likely to be white (74.1% vs 75.2%), have coronary artery disease (29.7% vs 33.4%), use aspirin (68.7% vs 72.4%), and have heparin reversal with protamine (15.5% vs 25.6%; all P < .05). CD patients were more likely to be obese (31.6% vs 27.0%), have an elective operation (82.6% vs 80.1%), ultrasound-guided access (75.5% vs 60.6%), and a larger access sheath (6.0 ± 1.0 F vs 5.5 ± 1.0 F; P < .05 for all). CD cases were less likely to develop any access site hematoma (2.55% vs 3.53%; P < .01) or a hematoma requiring reintervention (0.63% vs 1.26%; P < .01) and had no difference in access site stenosis or occlusion (0.30% vs 0.22%; P = .47) compared with no CD. On multivariable analysis, CD cases had significantly decreased odds of developing any access site hematoma (odds ratio, 0.75; 95% confidence interval, 0.59-0.95) and a hematoma requiring intervention (odds ratio, 0.56; 95% confidence interval, 0.38-0.81). A sensitivity analysis after coarsened exact matching confirmed these findings.ConclusionsIn this nationally representative sample, CD use for AA was associated with a lower odds of hematoma in selected patients. Extending the instructions for use indications for CDs to include femoral AA may decrease the incidence of access site complications, patient exposure to reintervention, and costs to the health care system

Circumnuclear Gas in Seyfert 1 Galaxies: Morphology, Kinematics, and Direct Measurement of Black Hole Masses

(Abridged) The two-dimensional distribution and kinematics of the molecular, ionized, and highly ionized gas in the nuclear regions of Seyfert 1 galaxies have been measured using high spatial resolution (~0''.09) near-infrared spectroscopy from NIRSPEC with adaptive optics on the Keck telescope. Molecular hydrogen, H2, is detected in all nine Seyfert 1 galaxies and, in the majority of galaxies, has a spatially resolved flux distribution. In contrast, the narrow component of the BrG emission has a distribution consistent with that of the K-band continuum. In general, the kinematics of H2 are consistent with thin disk rotation, with a velocity gradient of over 100 km/s measured across the central 0''.5 in three galaxies, and across the central 1''.5 in two galaxies. The kinematics of BrG are in agreement with the H2 rotation, except in all four cases the central 0''.5 is either blue- or redshifted by more than 75 km/s. The highly ionized gas, measured with the [Ca VIII] and [Si VII] coronal lines, is spatially and kinematically consistent with BrG in the central 0''.5. Dynamical models have been fitted to the two-dimensional H2 kinematics, taking into account the stellar mass distribution, the emission line flux distribution, and the point spread function. For NGC 3227 the modeling indicates a black hole mass of Mbh = 2.0{+1.0/-0.4} x 10^7 Msun, and for NGC 4151 Mbh = 3.0{+0.75/-2.2} x 10^7 Msun. In NGC 7469 the best fit model gives Mbh < 5.0 x 10^7 Msun. In all three galaxies, modeling suggests a near face-on disk inclination angle, which is consistent with the unification theory of active galaxies. The direct black hole mass estimates verify that masses determined from the technique of reverberation mapping are accurate to within a factor of three with no additional systematic errors.Comment: 43 pages, including 47 figures; Accepted for publication in ApJ. All 2-D maps (in high resolution) are available at http://www.astro.ucla.edu/~ehicks . Minor changes to the text and updated reverberation mapped black hole mass estimates; the conclusions are unchange

Multiwavelength Mass Comparisons of the z~0.3 CNOC Cluster Sample

Results are presented from a detailed analysis of optical and X-ray observations of moderate-redshift galaxy clusters from the Canadian Network for Observational Cosmology (CNOC) subsample of the EMSS. The combination of extensive optical and deep X-ray observations of these clusters make them ideal candidates for multiwavelength mass comparison studies. X-ray surface brightness profiles of 14 clusters with 0.17<z<0.55 are constructed from Chandra observations and fit to single and double beta-models. Spatially resolved temperature analysis is performed, indicating that five of the clusters in this sample exhibit temperature gradients within their inner 60-200 kpc. Integrated spectra extracted within R_2500 provide temperature, abundance, and luminosity information. Under assumptions of hydrostatic equilibrium and spherical symmetry, we derive gas and total masses within R_2500 and R_200. We find an average gas mass fraction within R_200 of 0.136 +/- 0.004, resulting in Omega_m=0.28 +/- 0.01 (formal error). We also derive dynamical masses for these clusters to R_200. We find no systematic bias between X-ray and dynamical methods across the sample, with an average M(dyn)/M(X-ray) = 0.97 +/- 0.05. We also compare X-ray masses to weak lensing mass estimates of a subset of our sample, resulting in a weighted average of M(lens)/M(X-ray) of 0.99 +/- 0.07. We investigate X-ray scaling relationships and find powerlaw slopes which are slightly steeper than the predictions of self-similar models, with an E(z)^(-1) Lx-Tx slope of 2.4 +/- 0.2 and an E(z) M_2500-Tx slope of 1.7 +/- 0.1. Relationships between red-sequence optical richness (B_gc,red) and global cluster X-ray properties (Tx, Lx and M_2500) are also examined and fitted.Comment: Astrophysical Journal, 48 pages, 11 figures, LaTeX. Added correction to surface brightness normalization of MS1512.4+3647, corrections to sample gas mass fractions and calculated value of Omega_m. Figure resolution has been reduced to comply with astro-ph upload requirement

Recent Flight Test Results of the Joint CIAM-NASA Mach 6.5 Scramjet Flight Program

Under a contract with NASA, a joint Central Institute of Aviation Motors (CIAM) and NASA team recently conducted the fourth flight test of a dual-mode scramjet aboard the CIAM Hypersonic Flying Laboratory, 'Kholod'. With an aim test Mach 6.5 objective, the successful launch was conducted at the Sary Shagan test range in central Kazakstan on February 12, 1998. Ground-launch, rocket boosted by a modified Russian SA5 missile, the redesigned scramjet was accelerated to a new maximum velocity greater than Mach 6.4. This launch allowed for the measurement of the fully supersonic combustion mode under actual flight conditions. The primary program objective was the flight-to-ground correlation of measured data with preflight analysis and wind-tunnel tests in Russia and potentially in the United States. This paper describes the development and objectives of the program as well as the technical details of the scramjet and SA5 redesign to achieve the Mach 6.5 aim test condition. An overview of the launch operation is also given. Finally, preliminary flight test results are presented and discussed

The LWA1 Radio Telescope

LWA1 is a new radio telescope operating in the frequency range 10-88 MHz, located in central New Mexico. The telescope consists of 258 pairs of dipole-type antennas whose outputs are individually digitized and formed into beams. Simultaneously, signals from all dipoles can be recorded using one of the instrument's "all dipoles" modes, facilitating all-sky imaging. Notable features of the instrument include high intrinsic sensitivity (about 6 kJy zenith system equivalent flux density), large instantaneous bandwidth (up to 78 MHz), and 4 independently-steerable beams utilizing digital "true time delay" beamforming. This paper summarizes the design of LWA1 and its performance as determined in commissioning experiments. We describe the method currently in use for array calibration, and report on measurements of sensitivity and beamwidth.Comment: 9 pages, 14 figures, accepted by IEEE Trans. Antennas & Propagation. Various minor changes from previous versio

Heat-capacity measurements under uniaxial pressure using a piezo-driven device

Y.S.L. acknowledges the support of a St Leonards scholarship from the University of St Andrews, the Engineering and Physical Sciences Research Council via the Scottish Condensed Matter Centre for Doctoral Training under Grant No. EP/G03673X/1, and the Max Planck Society.We report the development of a technique to measure heat capacity at large uniaxial pressure using a piezoelectric-driven device generating compressive and tensile strain in the sample. Our setup is optimized for temperatures ranging from 8 K down to millikelvin. Using an AC heat-capacity technique, we are able to achieve an extremely high resolution and to probe a homogeneously strained part of the sample. We demonstrate the capabilities of our setup on the unconventional superconductor Sr2RuO4. By replacing thermometer and adjusting the remaining setup accordingly, the temperature regime of the experiment can be adapted to other temperature ranges of interest.Publisher PDFPeer reviewe

Global assessment of nitrogen deposition effects on terrestrial plant diversity : a synthesis

Atmospheric nitrogen (N) deposition is it recognized threat to plant diversity ill temperate and northern parts of Europe and North America. This paper assesses evidence from field experiments for N deposition effects and thresholds for terrestrial plant diversity protection across a latitudinal range of main categories of ecosystems. from arctic and boreal systems to tropical forests. Current thinking on the mechanisms of N deposition effects on plant diversity, the global distribution of G200 ecoregions, and current and future (2030) estimates of atmospheric N-deposition rates are then used to identify the risks to plant diversity in all major ecosystem types now and in the future. This synthesis paper clearly shows that N accumulation is the main driver of changes to species composition across the whole range of different ecosystem types by driving the competitive interactions that lead to composition change and/or making conditions unfavorable for some species. Other effects such its direct toxicity of nitrogen gases and aerosols long-term negative effects of increased ammonium and ammonia availability, soil-mediated effects of acidification, and secondary stress and disturbance are more ecosystem, and site-specific and often play a supporting role. N deposition effects in mediterranean ecosystems have now been identified, leading to a first estimate of an effect threshold. Importantly, ecosystems thought of as not N limited, such as tropical and subtropical systems, may be more vulnerable in the regeneration phase. in situations where heterogeneity in N availability is reduced by atmospheric N deposition, on sandy soils, or in montane areas. Critical loads are effect thresholds for N deposition. and the critical load concept has helped European governments make progress toward reducing N loads on sensitive ecosystems. More needs to be done in Europe and North America. especially for the more sensitive ecosystem types. including several ecosystems of high conservation importance. The results of this assessment Show that the Vulnerable regions outside Europe and North America which have not received enough attention are ecoregions in eastern and Southern Asia (China, India), an important part of the mediterranean ecoregion (California, southern Europe). and in the coming decades several subtropical and tropical parts of Latin America and Africa. Reductions in plant diversity by increased atmospheric N deposition may be more widespread than first thought, and more targeted Studies are required in low background areas, especially in the G200 ecoregions