The continuing misuse of guidance in response to the pandemic

The Government has blurred the distinction between law and guidance in the coronavirus regulations, creating confusion among the public and police. Tom Hickman (University College London) says this normative ambiguity is an abuse of authority, and undermines Parliament’s right to scrutinise and approve new law. Despite objections from MPs and peers, it has reinstated the ... Continue

Studies into cytauxzoon and helminth infections of bobcats (Lynx rufus) of Northwest Arkansas

The purpose of this study was to determine the prevalence of Cytauxzoon felis and gastrointestinal helminth infections in bobcats (Lynx rufus) of Northwest Arkansas, an area known to have numerous cases of cytaux in domestic cats. Sixty bobcat carcasses were collected from trappers located in Mulberry and Decatur, Arkansas. Blood samples from the hearts were used to isolate Cytauxzoon DNA. Next, a polymerase chain reaction ( PCR) procedure coupled with gel-electrophoresis assay for the 18s region of extracted DNA were used to determine the presence of the protozoan in the bobcats at the time of harvest. Out of the 60 bobcats, 54 (90%) were positive for the protozoan’s infection. These findings indicate a large reservoir of Cytauxzoon for possible infection of domestic cats. Along with the detection of Cytauxzoon felis, intestinal helminths of the bobcats were collected and identified. The isolated helminths included Alaria marcianae, Ancylostoma sp., Molineus barbatus, Taenia sp., Spirometra mansonoides, Mesocestoides lineatus, Aonchotheca putorii, Physaloptera praeputialis and Toxocara cati. All helminths found were previously shown to be common in omnivorous and carnivorous sylvatic as well as domestic mammals of the region. It is amazing that bobcats are able to withstand both parasitic infections concurrently, as they roam the forests of Northwest Arkansas

Professional Sports Teams: Going Beyond the Core

Purpose - The addition of products to the core of matches by Professional Sports Teams (PSTs) has received much coverage. However, there has been limited work as to how their stadiums are used to stage non-sporting events. This paper investigates how clubs in the English Football League (EFL) use their venues to diversify into other markets. Design/methodology - Secondary sources were used to categorise the teams who played in the EFL by: average division turnover, stadium capacity and stadium age. Semi-structured interviews were held with a member of the commercial teams of 21 clubs. Findings - Clubs use their stadiums to supply a range of products and working with partners is commonplace. These products are targeted at a range of stakeholders, such as supporters, the local community and regionally based organisations. In addition to their own efforts, increased geographical coverage for clubs usually develops in three ways: via internal marketing by local organisations who use the facilities, agents who market the stadium for the club, and the EFL who market the league/clubs holistically. Research limitations/implications - The use of a stadium allows PSTs to diversify by providing new products for new markets. In this instance it has led to the development of capabilities in areas such as conferencing, funerals and weddings. Originality - This is one of the first papers to examine the capabilities developed by PSTs that lie outside the staging of matches

Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes

Funded by •ERC. Grant Number: 284167 •NIH. Grant Number: 1RO1DK0921127-01 •NWO. Grant Numbers: 463-06-001, 451-04-034Peer reviewedPublisher PD

High-Potency Cannabis, Mental Health and Substance Use in Adolescence:Results from a UK General Population Sample

Importance Cannabis use is consistently linked to poorer mental health outcomes, and there is evidence that use of higher-potency cannabis increases these risks. To date, no studies have described the association between cannabis potency and concurrent mental health in a general population sample or addressed confounding using longitudinal data. Objective To explore the association between cannabis potency and substance use and mental health outcomes, accounting for preceding mental health and frequency of cannabis use. Design, Setting, and Participants This cohort study used data from the Avon Longitudinal Study of Parents and Children, a UK birth cohort of participants born between April 1, 1991, and December 31, 1992. Present data on outcomes and exposures were collected between June 2015 and October 2017 from 1087 participants at 24 years of age who reported recent cannabis use. Exposures Self-reported type of cannabis most commonly used in the past year, coded to a binary exposure of use of high-potency cannabis or lower-potency cannabis. Main Outcomes and Measures Outcomes were reported frequency of cannabis use, reported cannabis use problems, recent use of other illicit drugs, tobacco dependence, alcohol use disorder, depression, generalized anxiety disorder, and psychotic-like experiences. The study used secondary data; consequently, the hypotheses were formulated after data collection. Results Past-year cannabis use was reported by 1087 participants (580 women; mean [SD] age at onset of cannabis use, 16.7 [3.0] years). Of these, 141 participants (13.0%) reported the use of high-potency cannabis. Use of high-potency cannabis was associated with increased frequency of cannabis use (adjusted odds ratio [AOR], 4.38; 95% CI, 2.89-6.63), cannabis problems (AOR, 4.08; 95% CI, 1.41-11.81), and increased likelihood of anxiety disorder (AOR, 1.92; 95% CI, 1.11-3.32). Adjustment for frequency of cannabis use attenuated the association with psychotic experiences (AOR 1.29; 95% CI, 0.67-2.50), tobacco dependence (AOR, 1.42; 95% CI, 0.89-2.27), and other illicit drug use (AOR, 1.29; 95% CI, 0.77-2.17). There was no evidence of association between the use of high-potency cannabis and alcohol use disorder or depression. Conclusions and Relevance To our knowledge, this study provides the first general population evidence suggesting that the use of high-potency cannabis is associated with mental health and addiction. Limiting the availability of high-potency cannabis may be associated with a reduction in the number of individuals who develop cannabis use disorders, the prevention of cannabis use from escalating to a regular behavior, and a reduction in the risk of mental health disorders

Judicial Review, Irrationality, and the Limits of Intervention by the Courts

When exercising judicial review, the courts, on occasions, have intervened in circumstances where administrative decisions were not irrational. However, these low standards of judicial intervention are arguably constitutional, especially since the enactment of the Human Rights Act 1998 (HRA). To this end, this article seeks to establish a zone of executive decision-making, for reasons of democracy, where the courts are clearly excluded. But it is unable to do so. Does this mean, therefore, that judicial intervention on the grounds of irrationality exists without limit? Assuming this to be the case, it is suggested that the courts should show greater respect to the administrative branch of the state where it has genuinely sought to engage with the legal process in arriving at its decisions

Report of the Independent Commission on UK Public Health Emergency Powers

The Independent Commission on UK Public Health Emergency Powers was established in October 2022 and is chaired by the Rt. Hon. Sir Jack Beatson FBA, formerly a member of the Court of Appeal of England and Wales, who has worked alongside 12 Commissioners with backgrounds in law, public health and other areas of parliamentary governance and public policy. The Commission was supported by a research team from the Bingham Centre for the Rule of Law which served as its secretariat. It considered both written and oral evidence, and comments on its preliminary findings, from 82 individuals and organisations across the UK and in 10 other jurisdictionsThe report makes 44 recommendations to enable the four nations in the UK to better protect the rule of law and good governance in future public health emergencies, while acting quickly to secure timely and effective public health outcomes. The recommendations focus on the design of primary and secondary legislation (including the protection of human rights), the enhancement of parliamentary procedures, improvement of legal certainty, and the appropriateness of enforcement action. Findings have been shared with both the UK and Scottish public inquiries into Covid-19, and with senior health officials in each of the four nations

Independent Commission on UK Public Health Emergency Powers:Final Report

The Independent Commission on UK Public Health Emergency Powers reviewed emergency public health laws and parliamentary procedures in the four UK nations. We considered how far these laws and procedures could be enhanced so as to better protect the rule of law and promote accountability, transparency and parliamentary control of executive action. We also undertook comparative research; reviewing public health emergency powers in ten foreign jurisdictions chosen because of their similarities to the UK’s parliamentary system and the efficacy of their legal responses to Covid-19. Throughout our inquiry we kept foremost in our minds the need for governments to act quickly in an emergency to secure timely and effective public health outcomes

Fundamental challenges in designing a collaborative travel app

The growing capabilities of smartphones have opened up new opportunities for travel coordination and transport is a fertile area for app development. One stream of development is apps that enable collaborative travel, either in the form of lift sharing or collaborative shopping, but despite growing interest from governmental agencies, there is little evidence of the efficacy of such apps. Based on trials of purpose built travel collaboration apps, deployed in tourism, urban and rural residential communities, and logistics, this paper analyses the fundamental challenges facing users adopting such travel apps. The findings suggest that transport practitioners, policy makers and app developers need to better understand the challenges associated with attracting users, the use of incentives and the types of communities most appropriate to implement collaborative travel concepts using such approaches. Also, how the users’ sense of time pressure and the issues around reciprocal exchange can impact on their long-term success and wider adoption