2,193 research outputs found

    Approaches Necessary for Reflection about a Community Ethics in Mathematical Education

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    La relación entre ética y educación no es un tema nuevo, hay un interés permanente por responder a la pregunta: ¿qué presencia tiene la ética en cada sociedad? En el campo de la educación también se mantiene la pregunta ¿qué educación es necesaria para cada sociedad? Ética y educación se vinculan en los procesos transformadores de las sociedades. La pregunta que orienta la escritura de este artículo es ¿qué caracterización de ética es necesaria en el campo de la educación matemática? Se presenta inicialmente una caracterización de origen filosófica con aportes de la teoría de la argumentación, a continuación se profundiza en la relación ética-educación matemática, estableciendo un vínculo inmediato con la teoría de la objetivación, y finalmente se presentan voces de profesores y estudiantes señalando la necesidad del componente ético en el campo de la educación matemática.The relationship between ethics and education is not a new issue; there is a permanent interest in answering the question: what is the presence of ethics in each society? In the field of education, the question remains: what education is necessary for each society? Ethics and education are linked in the transforming processes of societies. The question that guides the writing of this article is what characterization of ethics is necessary in the field of mathematics education? It is presented initially a characterization of philosophical origin with contributions of the theory of the argumentation, then deepens in the relation ethics-mathematical education, establishing an immediate link with the theory of the objectification, and finally presents the voices of professors and students pointing out the need for the ethical component in the field of mathematical education.Uniersidad de Granada. Grupo de Investigación Didáctica de la Matemática: Pensamiento Numérico (FQM-193)Las autoras agradecen a la Comisión Europea por su apoyo y financiación parcial y a los socios de los proyectos: ERASMUS+: Higher Education – International Capacity Building - ACACIA – (561754-EPP-1-2015-1-CO-EPKA2-CBHE-JP). Este trabajo está también parcialmente apoyado por AIDETC del Programa Nacional Colciencias código 1419-6614-44765

    Collective behavior and virulence arsenal of the fish pathogen Piscirickettsia salmonis in the biofilm realm

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    Piscirickettsiosis is a fish disease caused by the Gram-negative bacterium Piscirickettsia salmonis. This disease has a high socio-economic impact on the Chilean salmonid aquaculture industry. The bacterium has a cryptic character in the environment and their main reservoirs are yet unknown. Bacterial biofilms represent a ubiquitous mechanism of cell persistence in diverse natural environments and a risk factor for the pathogenesis of several infectious diseases, but their microbiological significance for waterborne veterinary diseases, including piscirickettsiosis, have seldom been evaluated. This study analyzed the in vitro biofilm behavior of P. salmonis LF-89T (genogroup LF-89) and CA5 (genogroup EM-90) using a multi-method approach and elucidated the potential arsenal of virulence of the P. salmonis LF-89T type strain in its biofilm state. P. salmonis exhibited a quick kinetics of biofilm formation that followed a multi-step and highly strain-dependent process. There were no major differences in enzymatic profiles or significant differences in cytotoxicity (as tested on the Chinook salmon embryo cell line) between biofilm-derived bacteria and planktonic equivalents. The potential arsenal of virulence of P. salmonis LF-89T in biofilms, as determined by whole-transcriptome sequencing and differential gene expression analysis, consisted of genes involved in cell adhesion, polysaccharide biosynthesis, transcriptional regulation, and gene mobility, among others. Importantly, the global gene expression profiles of P. salmonis LF-89T were not enriched with virulence-related genes upregulated in biofilm development stages at 24 and 48 h. An enrichment in virulence-related genes exclusively expressed in biofilms was also undetected. These results indicate that early and mature biofilm development stages of P. salmonis LF-89T were transcriptionally no more virulent than their planktonic counterparts, which was supported by cytotoxic trials, which, in turn, revealed that both modes of growth induced important and very similar levels of cytotoxicity on the salmon cell line. Our results suggest that the aforementioned biofilm development stages do not represent hot spots of virulence compared with planktonic counterparts. This study provides the first transcriptomic catalogue to select specific genes that could be useful to prevent or control the (in vitro and/or in vivo) adherence and/or biofilm formation by P. salmonis and gain further insights into piscirickettsiosis pathogenesis

    Incidencia de eventos adversos asociados a dispositivosmédicos en una institución de salud en Colombia

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    Este artículo presenta los resultados de un estudio retrospectivo de eventos adversos asociados a dispositivos médicos (EADMS), presentados en el período de enero a junio de 2010 en el servicio de Cirugía de una institución prestadora de saludo (IPS) en Colombia.This paper presents the results of a retrospective study of adverse events associated with medical devices (AEAMDS), presented during the period of January through June of 2010 in the Surgery Department of a healthcare institution in Colombia

    Measurement Invariance of the Short UCLA Loneliness Scale in Spanish and Peruvian Old People: Latent Mean Differences and Evidence for Differential Effects on Perceived Health

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    The objectives of this study are to evaluate the measurement invariance of the University of California Los Angeles Loneliness Scale (UCLA-LS) three-item version (UCLA-LS-3) in older adults in Peru and Spain, to compare the latent means of loneliness, and to evaluate the psychometric properties of the scale with Item Response Theory (IRT) models, and evaluate the possible moderating effects of the country on loneliness-health relationships. Peruvian sample was composed of 235 old adults from the city of Lima. The Spanish sample was composed of 443 old adults. The three-factor structure of RUCLA-3 anchored to the health measure fitted the data reasonably well in Spain and Peru. The R-UCLA-3 may be considered invariant for these two samples. The latent means of loneliness are different, the Peruvian average of loneliness being greater than that of Spain. The R-UCLA-3 is an invariant measure in older adults in Peru and Spain, with adequate psychometric properties through IRT models

    Expression of USP18 and IL2RA is increased in individuals receiving latent tuberculosis treatment with isoniazid

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    Background. The treatment of latent tuberculosis infection (LTBI) in individuals at risk of reactivation is essential for tuberculosis control. However, blood biomarkers associated with LTBI treatment have not been identified. Methods. Blood samples from tuberculin skin test (TST) reactive individuals were collected before and after one and six months of isoniazid (INH) therapy. Peripheral mononuclear cells (PBMC) were isolated, and an in-house interferon-γ release assay (IGRA) was performed. Expression of chemokine ligand 4 (CCL4), chemokine ligand 10 (CXCL10), chemokine ligand 11 (CXCL11), interferon alpha (IFNA), radical S-adenosyl methionine domain-containing 2 (RSAD2), ubiquitin-specific peptidase 18 (USP18), interferon-induced protein 44 (IFI44), interferon-induced protein 44 like (IFI44L), interferon-induced protein tetratricopeptide repeats 1(IFIT1), and interleukin 2 receptor subunit alpha (IL2RA) mRNA levels were assessed by qPCR before, during, and after INH treatment. Results. We observed significantly lower relative abundances of USP18, IFI44L, IFNA, and IL2RA transcripts in PBMC from IGRA-positive individuals compared to levels in IGRA-negative individuals before INH therapy. Also, relative abundance of CXCL11 was significantly lower in IGRA-positive than in IGRA-negative individuals before and after one month of INH therapy. However, the relative abundance of CCL4, CXCL10, and CXCL11 mRNA was significantly decreased and that of IL2RA and USP18 significantly increased after INH therapy, regardless of the IGRA result. Our results show that USP18, IFI44L, IFIT1, and IL2RA relative abundances increased significantly, meanwhile the relative abundance of CCL4, CXCL11, and IFNA decreased significantly after six months of INH therapy in TST-positive individuals. Conclusions. Changes in the profiles of USP18, IL2RA, IFNA, CCL4, and CXCL11 expressions during INH treatment in TST-positive individuals, regardless of IGRA status, are potential tools for monitoring latent tuberculosis treatment

    ACORDE a Cosmic Ray Detector for ALICE

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    ACORDE is one of the ALICE detectors, presently under construction at CERN. It consists of an array of plastic scintillator counters placed on the three upper faces of the ALICE magnet. It will act as a cosmic ray trigger, and, together with other ALICE sub-detectors, will provide precise information on cosmic rays with primary energies around 1015÷101710^{15} \div 10^{-17} eV. Here we describe the design review of ACORDE along with the present status and integration into ALICE.Comment: 2 pages, 2 figures. Conference Proceeding of the X Pisa Meeting on Advanced Detectors, to be published in a special issue of Nuclear Instruments and Method

    Evaluación sanitaria en toros de fomento del departamento de Cundinamarca, 1. Estudios bacteriológicos

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    Se examinaron 46 toros de diferentes razas pertenecientes a 18 granjas de fomento, situadas en igual número de municipios del departamento de Cundinamarca. Estos animales fueron examinados 3 veces con intervalos de un mes para brucelosis, leptospirosis y salmonelosis mediante exámenes serológicos y para campilobacteriosis, brucelosis, trichomoniasis y otro tipo de gérmenes corrientes en lavados prepuciales. 11 toros (23.9 por ciento) fueron positivos a trichomoniasis, 8 (17.3 por ciento) a campilobacteriosis, 20 (43.4 por ciento) reactores a salmonelosis, 13 (28.2 por ciento) reactores a brucelosis, 24 (52.17 por ciento) reactores a leptospirosis. De todos los animales examinados, 35 (76.0 por ciento) positivos a una o varias entidades fueron mencionadas anteriormente. Estos toros en el transcurso de un año han servido un total de 812 vacas de los municipios donde están localizadas las fincas de Fomento y alrededor de las cuales hay una población de 511312 bovinos. Se discute las posibilidades de diseminación de las enfermedades y sus posibilidades de contro

    Winegrowers’ decision-making: A pan-European perspective on pesticide use and inter-row management

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    European viticultural landscapes not only support a significant share of rural livelihoods and cultural traditions, but also conserve biodiversity and sustain various ecosystem services. Winegrowers' practices of inter-row management (including whether to have vegetation in the inter-rows, type of vegetation, duration of vegetation cover, and soil tillage) and pesticide use (including herbicides in the inter-rows, fungicides, insecticides, and pheromone dispensers as an alternative) can affect these services. This study aims to understand winegrowers' decision-making driven by their personal characteristics, attitudes and beliefs towards viticultural practices, physical properties of vineyards, and farm management characteristics in five European winegrowing regions. These include Palatinate in Germany, Leithaberg in Austria, Tarnave in Romania, Bordeaux in France, and Montilla-Moriles in Spain. Based on a questionnaire survey, we constructed decision trees for each behaviour per case study as well as in a generic European model. We found factors that best explain how winegrowers manage their inter-rows and use pesticides. Results showed that not only do behaviours of winegrowers vary drastically across the case studies, but also the factors that explain most behaviours: farmers' attitudes and beliefs and farm management characteristics. This implies the importance of attitudes and beliefs – which are under-researched as compared to other factors – in understanding farmers’ behaviour. With the driving factors found to vary per case study, our results also imply the need for locally-adapted policies. Furthermore, our results suggest that the effects of climate change on European viticultural landscapes concern not only shifting production regions and changes in yields, but also changing pressure of pests and diseases. Any long-term behavioural change requires efforts from many stakeholders.This research was funded by the research project SECBIVIT which was funded through the 2017–2018 Belmont Forum and BiodivERsA joint call for research proposals, under the BiodivScen ERA-Net COFUND programme, with the funding organisations: Agencia Estatal de Investigación (Ministerio de ciencia e innovación/Spain), Austrian Science Fund (FWF) (grant number I 4025-B32), Federal Ministry of Education and Research (BMBF/Germany) through VDI/VDE Innovation + Technik GmbH, DLR Projektträger, French National Research Agency (ANR), Netherlands Organisation for Scientific Research (NWO), National Science Foundation (Grant #1850943) and Romanian Executive Agency for Higher Education, Research, Development and Innovation Funding (UEFISCDI). We would like to thank all winegrowers who participated in the focus groups, online questionnaires and personal interviews and the extension services who distributed our online questionnaire through their e-mail distribution list (DLR-Rheinpfalz)

    Ayotzinapa y la crisis del estado neoliberal mexicano

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    ¿Qué pasó en Ayotzinapa? Es la pregunta que surgió el 26 de septiembre de 2014, que no encuentra una respuesta satisfactoria pese a la intervención de actores de distintas instancias, niveles y nacionalidades, y al esbozo de múltiples hipótesis sobre los enfrentamientos registrados en Iguala, Guerrero, que derivaron en la muerte de varias personas y la desaparición de 43 estudiantes de la Normal Rural “Isidro Burgos”, en una tragedia que evidenció la crisis que atraviesa el estado mexicano y que afecta a todo el país. A partir de lo acontecido en Ayotzinapa y con base en la teoría general de los campos de Pierre Bourdieu y su propuesta de análisis teórico metodológico sobre el estado, en esta obra se realiza un análisis de la práctica sistemática y generalizada de las desapariciones forzadas en México, con el fin de ofrecer otra manera de comprender el entretejido político–económico–social que hace posible este grave fenómeno, que desgarra tanto a familias como a la comunidad. La herida abierta por Ayotzinapa sangra y el objetivo último de este libro es contribuir a evitar que se cierre en tanto no se responda la interrogante de qué pasó ahí y que crímenes de lesa humanidad como este sigan aconteciendo en México.ITESO, A.C
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