Trigger efficiencies of a proposed beam monitoring detector (BeBe) for p+p collisions at NICA energies

The Multipurpose Detector (MPD) consists of a typical array of sub-detectors to study the nuclear matter originating from the collisions of beams provided by the Nuclotron-based Ion Collider fAcility (NICA). A beam monitoring detector~(BeBe) is proposed for stage 2 of MPD to increase the trigger capabilities. BeBe is constituted of two plastic scintillator disks segmented in 80 cells $\pm~2~m$ away from the interaction point of MPD. Laboratory measurements to obtain the energy resolution of an individual BeBe cell prototype are presented. It is shown that an energy resolution of $22\pm6\%$ can be obtained. Based on Monte Carlo simulations, the trigger efficiencies of the BeBe are presented for p+p collisions at 11~GeV considering a threshold in the energy loss of the charged particles reaching the detector

Characteristics of the ALICE Silicon Drift Detector

A Silicon Drift Detector (SDD) with an active area of 7.0 x 7.5 cm2 has been designed, produced and tested for the ALICE Inner Tracking System. The development of the SDD has been focussed on the capability of the detector to work without an external support to the integrated high voltage divider. Severalfeatures have been implemented in the design in order to increase the robustness and the long-term electrical stability of the detector. One of the prototypes has been tested in a pion beam at the CERN SPS. Preliminary results on the position resolution are given

Ampliación y generación de espacios adecuados a la Caja Popular Colonias Unidas

En este reporte se mostrará el trabajo de todo un semestre del equipo que se encargó de diseñar los planos ejecutivos de la caja popular “Colonias Unidas” resolviendo sus necesidades y problemas. se aborda la problemática general de la zona, hasta llegar a las necesidades más específicas de esta, se plantean los objetivos generales y particulares que se quieren lograr y se propone un taller decaptación de agua que pueda utilizar la caja popular y lo puedan implementar sussocios

Ampliación y generación de espacios adecuados a la Caja Popular Colonias Unidas

ITESO, A.C

Correction of Dopant Concentration Fluctuation Effects in Silicon Drift Detectors

Dopant fluctuations in silicon wafers are responsible for systematic errors in the determination of the particle crossing point in silicon drift detectors. In this paper, we report on the first large scale measurement of this effect by means of a particle beam. A significant improvement of the anodic resolution has been obtained by correcting for these systematic deviations

Integrated Genomic Analysis of Chromosomal Alterations and Mutations in B-Cell Acute Lymphoblastic Leukemia Reveals Distinct Genetic Profiles at Relapse

The clonal basis of relapse in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is complex and not fully understood. Next-generation sequencing (NGS), array comparative genomic hybridization (aCGH), and multiplex ligation-dependent probe amplification (MLPA) were carried out in matched diagnosis-relapse samples from 13 BCP-ALL patients to identify patterns of genetic evolution that could account for the phenotypic changes associated with disease relapse. The integrative genomic analysis of aCGH, MLPA and NGS revealed that 100% of the BCP-ALL patients showed at least one genetic alteration at diagnosis and relapse. In addition, there was a significant increase in the frequency of chromosomal lesions at the time of relapse (p = 0.019). MLPA and aCGH techniques showed that IKZF1 was the most frequently deleted gene. TP53 was the most frequently mutated gene at relapse. Two TP53 mutations were detected only at relapse, whereas the three others showed an increase in their mutational burden at relapse. Clonal evolution patterns were heterogeneous, involving the acquisition, loss and maintenance of lesions at relapse. Therefore, this study provides additional evidence that BCP-ALL is a genetically dynamic disease with distinct genetic profiles at diagnosis and relapse. Integrative NGS, aCGH and MLPA analysis enables better molecular characterization of the genetic profile in BCP-ALL patients during the evolution from diagnosis to relapse

Recent Developments on the Silicon Drift Detector readout scheme for the ALICE Inner Tracking System

Proposal of abstract for LEB99, Snowmass, Colorado, 20-24 September 1999Recent developments of the Silicon Drift Detector (SDD) readout system for the ALICE Experiment are presented. The foreseen readout system is based on 2 main units. The first unit consists of a low noise preamplifier, an analog memory which continuously samples the amplifier output, an A/D converter and a digital memory. When the trigger signal validates the analog data, the ADCs convert the samples into a digital form and store them into the digital memory. The second unit performs the zero suppression/data compression operations. In this paper the status of the design is presented, together with the test results of the A/D converter, the multi-event buffer and the compression unit prototype.Summary:In the Inner Tracker System (ITS) of the ALICE experiment the third and the fourth layer of the detectors are SDDs. These detectors provide the measurement of both the energy deposition and the bi-dimensional position of the track. In terms of readout an SDD can be viewed as a matrix, where the rows are the detector anodes and the columns are the samples to be read during the drift time; therefore, a very large amount of data has to be amplified, converted in digital form and preprocessed in order to avoid the storage of non-significatn data.Since the electron mobility is a strong temperature function, detector temperature has to be kept constant; on the other hand, it is not possible to use very efficient cooling systems because the amount of material in this area is very limited, so the power budget for the electronic readout is very low (less than 6 mW/anode).The simplest solution would be to send the analog signals outside the sensitive area immediately after a preamplification; unfortunately, the ratio between the number of channels (around 200 000) and the space available is so high that the simple solution of sending all the SDD anodes output outside teh detector zone after a low-noise amplification is not practically manageable.Abstract:The adopted solution is based on three main units:(i) A front-end chip that performs low noise amplification, fast analog storage and A/D conversion(ii) A multi-event digital buffer for data derandomization(iii) A data compression/zero suppression and system control boardThe first two units are distributed on the ladders near the detectors and have stringent power and space requirements, while the third unit is placed at both ends of the ladders and in boxes placed on both ends of the TPC detector.The first unit is the most critical part of the system. It works as follows: the detector signals are continuously amplified, sampled and stored in the analog memory with a frequency of 40 MSamples/s The L0d trigger signal stops the write operation, while the L1 trigger signal starts the conversion phase. This phase will continue until the event data are stored in the event buffer if the L2y confirm trigger signal is received, or rejected if the L2n abort signal will be issued by the trigger system.Prototypes of the three parts have been designed and tested while the full chip is currently under design. Tests of the A/D converter will be presented.The multi-event buffer purpose is to de-randomize the even data in order to reduce the transmission speed. Preliminary tests of the first prototype will be presented.The board placed at the end of the ladders performs various functions. It reduces the amount of data through various cascaded algorithms with variable parameters and transmits the data to the SIU board. It also controls the test and slow control system for the ladder circuitry. Tests of the FPGA-based prototypes will be presented.Special care has been taken for the test problem. The ASICs designed are provided of a test control port based on teh IEEE 1149.1 JTAG standard. The same protocol is used for downloading configuration information

The Silicon Drift Detector readout scheme for the Inner Tracking System of the ALICE Experiment

Presentation at Quark Matter '99, Torino, Italy, 10-15 May 1999The Silicon Drift Detectors (SDDs) provide, through the measurement of the drift time of the charge deposited by the particle which crosses the detector, information on the impact point and on the energy deposition. The foreseen readout scheme is based on a single chip implementation of an integrated circuit that includes low-noise amplification, fast analog strorage and analog to digital conversion, thus avoiding the problems related to the analog signal transmission. A multi-event buffer that reduces the transmission bandwidth and a data compression/zero suppression unit complete the architecture.Abstract:In this paper, the system components design is described, together with the results of the first prototypes

Alternative Eco-Friendly Methods in the Control of Post-Harvest Decay of Tropical and Subtropical Fruits

The effectiveness on several fruits by the application of alternative methods against fungi is summarized in the present chapter. Several investigations have reported the efficacy of these technologies for controlling fungal infections. Currently, high post-harvest loses have been reported due to several factors such as inefficient management, lack of training for farmers, and problems with appropriate conditions for storage of fruits and vegetables. Even now, in many countries, post-harvest disease control is led by the application of chemical fungicides. However, in this time, awareness about fungi resistance, environmental, and health issues has led to the research of eco-friendly and effective alternatives for disease management. The pathogen establishment on fruits can be affected by the application of GRAS compounds like chitosan, essential oils, salts, among others; besides, their efficacy can be enhanced by their combination with other technologies like ultrasound. Thus, the applications of these alternatives are suitable approaches for post-harvest management of fruits