Selecciones de los poemas de don José María Heredia

Primer libro de poesías de Jose María Heredia Y Heredia, que se le publicara en Cuba, cuyo editor fue el inglés James Kennedy, edición bilingüe en inglés y español. Una copia del ejemplar está depositado en la “Biblioteca del Congreso” de Estados Unidos

Colección Histórica Cubana y Americana, dirigida por Emilio Roig de Leuchsenring, Historiador de la Ciudad de la Habana.

Se trata de la Publicación más completa hasta ahora de las poesías de José María Heredia y Heredia con semblanzas y anotaciones a pie de página hechas por los principales heredianos cubanos de principios del siglo XX: Emilio Roig de Leuchsenring, Francisco González del Valle. Una copia del documento se encuentra en la Biblioteca Virtual “Miguel de Cervantes”, www.cervantesvirtual.co

Homenaje de la Ciudad de la Habana en el centenario de la Muerte de Heredia (1839-1939) Vol. I

Se trata de la Publicación más completa hasta ahora de las poesías de José María Heredia y Heredia con semblanzas y anotaciones a pie de página hechas por los principales heredianos cubanos de principios del siglo XX: Emilio Roig de Leuchsenring, Francisco González del Valle. Una copia del documento se encuentra en la Biblioteca Virtual “Miguel de Cervantes”, www.cervantesvirtual.co

Comparação de três sistemas de medição diferentes para avaliar a altura do salto vertical

Introduction: The numerous instruments used to measure jump height use different technologies and calculations that can provide variable results. Objective: This study compared the countermovement jump (CMJ) height assessed with a wearable 3D inertial measurement unit (IMU), using flight time and the numerical integration method with a force platform and photocells. Methods: Forty CMJs were analysed, starting from an upright standing position with the hands placed on the waist. Twenty healthy volunteers completed 2 CMJs, which were simultaneously assessed using an IMU placed on the subject’s sacrum, a force platform (considered the gold standard method) and photocells. The maximum height of each CMJ was measured. Results: The results showed a significant overestimation (p<0.001) in jump height for the IMU using the numerical integration method when compared to the force platform (+7 cm). Excellent intraclass correlation coefficients (ICCs) were obtained with the flight time equations for the different types of measurement equipment. Fair to good ICCs were obtained with the IMU using the numerical integration method and force platform. Conclusion: In conclusion, the jump height obtained with the IMU using the numerical integration method showed the poorest agreement compared to the force platform.Introducción: Los numerosos instrumentos usados para medir la altura del salto emplean diferentes tecnologías y cálculos que pueden suministrar resultados variables. Objetivo: Este estudio comparó la altura del salto contramovimiento (SCM) con una un sistema inercial 3D (IMU) portátil, usando el tiempo de vuelo y el método de integración numérica, con plataforma de fuerza y fotocélulas. Métodos: Cuarenta SCMs fueron analizados a partir de la posición ortostática con las manos en la cintura. Veinte voluntarios saludables concluyeron dos SCMs que fueron evaluados simultáneamente con un IMU colocada en el sacro del individuo, una plataforma de fuerza (considerado el método de referencia) y fotocélulas. Fue medida la altura máxima de cada SCM. Resultados: Los resultados mostraron una sobreestimación significativa (p <0,001) de la altura del salto para la IMU con el método de integración numérica, en comparación con la plataforma de fuerza (+7 cm). Fueron obtenidos excelentes coeficientes de correlación intraclase (ICCs) con las ecuaciones de tiempo de vuelo entre los equipamientos de medición. Fueron obtenidos resultados de regulares a buenos de ICC con la IMU por el método de integración numérica y la plataforma de fuerza. Conclusión: La altura de salto obtenida con la IMU con el método de integración numérica mostró la peor concordancia en comparación con la plataforma de fuerza.Introdução: Os numerosos instrumentos usados para medir a altura de salto empregam diferentes tecnologias e cálculos que podem fornecer resultados variáveis. Objetivo: Este estudo comparou a altura de salto contramovimento (SCM) com uma unidade de medida inercial 3D (UMI) portátil, usando o tempo de voo e o método de integração numérica, com plataforma de força e fotocélulas. Métodos: Quarenta SCMs foram analisados a partir da posição ortostática com as mãos na cintura. Vinte voluntários saudáveis concluíram 2 SCMs que foram avaliados simultaneamente com uma UMI colocada no sacro do indivíduo, uma plataforma de força (considerado o método de referência) e fotocélulas. A altura máxima de cada SCM foi medida. Resultados: Os resultados mostraram uma superestimação significativa (p < 0,001) da altura do salto para a UMI com o método de integração numérica, em comparação com a plataforma de força (+7 cm). Foram obtidos excelentes coeficientes de correlação intraclasse (ICCs) com as equações de tempo de voo entre os equipamentos de medição. Foram obtidos resultados de regulares a bons de ICC com a UMI pelo método de integração numérica e a plataforma de força. Conclusão: A altura de salto obtida com a UMI com o método de integração numérica mostrou a pior concordância em comparação com a plataforma de força.This work was funded by the Ministry of Education, Culture and Sports of Spain by grants (ref. FPU13/00162)

Polyester films obtained by noncatalyzed melt-condensation polymerization of aleuritic (9,10,16-Trihydroxyhexadecanoic) acid in air

To mimic nontoxic and fully biodegradable biopolymers like the plant cutin, polyester films from a natural occurring fatty polyhydroxyacid like aleuritic (9,10,16-trihydroxyhexadecanoic) acid have been prepared by noncatalyzed melt-polycondensation at moderate temperature (150°C) directly in air. The course of the reaction has been followed by infrared spectroscopy, 13C magic angle spinning nuclear magnetic resonance spectroscopy, differential scanning calorimetry and X-ray diffraction and well differentiated stages are observed. First, a high conversion esterification reaction leads to an amorphous rubbery, infusible, and insoluble material whose structure is made out of ester linkages mostly involving primary hydroxyls and partially branched by minor esterification with secondary ones. Following the esterification stage, the cleavage of vicinal secondary hydroxyls and further oxidation to carboxylic acid is observed at the near surface region of films. New carboxylic groups created also undergo esterification and generate cross-linking points within the polymer structure. Additionally, and despite the harsh preparation conditions used, very little additional side reaction like peroxidation and dehydration are observed. Results demonstrate the feasibility of polyester films fabrication from a reference fatty polyhydroxyacid like aleuritic acid by noncatalyzed melt-polycondensation directly in air. The methodology can potentially be extended to similar natural occurring hydroxyacids to obtain films and coatings to be used, for instance, as nontoxic and biodegradable food packaging materialPeer reviewe

Los últimos romanos. Tragedia en tres actos.

Obra de teatro adaptada por José María Heredia y Heredia cuyo texto base es un drama francés. El archivo es una copia del ejemplar resguardado en los fondos de la Biblioteca Nacional de Cuba "José Martí"

The cargo protein MAP17 (PDZK1IP1) regulates the cancer stem cell pool activating the Notch pathway by abducting NUMB

Purpose: Cancer stem cells (CSC) are self-renewing tumor cells, with the ability to generate diverse differentiated tumor cell subpopulations. They differ from normal stem cells in the deregulation of the mechanisms that normally control stem cell physiology. CSCs are the origin of metastasis and highly resistant to therapy. Therefore, the understanding of the CSC origin and deregulated pathways is important for tumor control. Experimental Design: We have included experiments in vitro, in cell lines and tumors of different origins. We have used patient-derived xenografts (PDX) and public transcriptomic databases of human tumors. Results: MAP17 (PDZKIP1), a small cargo protein overexpressed in tumors, interacts with NUMB through the PDZ-binding domain activating the Notch pathway, leading to an increase in stem cell factors and cancer-initiating–like cells. Identical behavior was mimicked by inhibiting NUMB. Conversely, MAP17 downregulation in a tumor cell line constitutively expressing this gene led to Notch pathway inactivation and a marked reduction of stemness. In PDX models, MAP17 levels directly correlated with tumorsphere formation capability. Finally, in human colon, breast, or lung there is a strong correlation of MAP17 expression with a signature of Notch and stem cell genes. Conclusions: MAP17 overexpression activates Notch pathway by sequestering NUMB. High levels of MAP17 correlated with tumorsphere formation and Notch and Stem gene transcription. Its direct modification causes direct alteration of tumorsphere number and Notch and Stem pathway transcription. This defines a new mechanism of Notch pathway activation and Stem cell pool increase that may be active in a large percentage of tumors.Ministerio de Economía y Competitividad PI15/00045, CTS-1848Junta de Andalucía PI-00-96-2014, PI-0306-201

Development of an Emergency Radio Beacon for Small Unmanned Aerial Vehicles

Emergency locator transmitters (ELTs) used to locate manned aircrafts are not well suited to find and recover small crashed unmanned aerial vehicles (UAVs). ELTs utilize an international satellite system for search and rescue (Cospas-Sarsat System), which should leverage its expensive resources to save lives as a priority. Besides, ELTs are too big and heavy to be used within small UAVs. Some of the existing solutions for this problem are based on receivers that detect signal strength, which may be a long and tedious process not suitable for user needs. Others do not have enough range or require radio license and expensive amateur radio receivers. This paper presents an emergency radio beacon specifically designed to locate small UAVs. It is triggered automatically in the event of a crash and allows finding and recovering a crashed UAV in a fast and simple way. It meets not only the required specifications of user-friendliness, size and weight of this kind of application, but also it is a high precision and low cost device. Besides, it has enough range and endurance. The experiments carried out show the operation of the proposed system