La Biblia Palabra de Dios en palabra humana

La biblia es la palabra de Dios en palabra humana. Se formó no de proposiciones divinas dictadas desde los cielos, sino a partir de un proceso histórico que comenzó por la iniciativade Dios de revelarse al ser humano de manera concreta en nuestra historia. Dios expresó su voluntad en hechos y palabras que el pueblo de Israel vivenció en su propia historia, al igual que las comunidades del primer siglo con Jesús de Nazaret. Dichas vivencias fueron vistas desde la fe como la actuación de Dios en el mundo, luego guardadas como memorias orales que posteriormente fueron puestas por escrito en la cual podemos leer hoy como Dios ha actuado a nuestro favor

Calliphoridae (Diptera) coletados em cadáveres humanos no Rio Grande do Norte

This paper reports a study on Calliphoridae associated to human corpus in Rio Grande do Norte State, Brazil. Collections of Calliphoridae were made in cadavers in different stages of decomposition taken to the Instituto Técnico e Científico de Polícia/Natal, from different regions of the state. The following species were collected: Chrysomya megacephala (Fabr.), Chrysomya albiceps (Wied.), Cochliomyia macellaria (Fabr.), Lucilia eximia (Wied.), Lucilia cuprina (Wied.) and Lucilia sp

Estudo para reaproveitamento de resíduo gerado na construção civil para produção de peças em fibra de vidro / Study for reuse of waste generated in civil construction for the production of fiberglass parts

Na indústria da construção civil são gerados resíduos tais como: argamassas, cerâmica, madeira e gesso, sendo que atualmente, a maior parte são depositados em aterros sanitários. Os empresários estão cada vez mais conscientes de que a proteção do meio ambiente é importante não só para garantir a sobrevivência do ser humano, mas também como oportunidade de negócios. Neste trabalho, foi avaliado a possibilidade de reaproveitamento do resíduo de gesso gerado na construção civil, na produção de peças em fibra de vidro. O gesso é considerado resíduo da classe C, ou seja, não possui destinação apropriada. Foram produzidos corpos de prova a partir de uma formulação padrão do mercado em que o gesso foi misturado com resina de poliéster que é utilizada na produção de peças em fibra de vidro em substituição ao talco que é utilizado como carga. As propriedades avaliadas foram: resistência mecânica a compressão, densidade aparente e absorção de água. Os resultados mostraram que os corpos de prova contendo gesso apresentaram resultados semelhantes à formulação padrão, e que pode ser usado para reduzir custos de produção e diminuir o impacto ambiental

The neural correlates of dreaming.

Consciousness never fades during waking. However, when awakened from sleep, we sometimes recall dreams and sometimes recall no experiences. Traditionally, dreaming has been identified with rapid eye-movement (REM) sleep, characterized by wake-like, globally 'activated', high-frequency electroencephalographic activity. However, dreaming also occurs in non-REM (NREM) sleep, characterized by prominent low-frequency activity. This challenges our understanding of the neural correlates of conscious experiences in sleep. Using high-density electroencephalography, we contrasted the presence and absence of dreaming in NREM and REM sleep. In both NREM and REM sleep, reports of dream experience were associated with local decreases in low-frequency activity in posterior cortical regions. High-frequency activity in these regions correlated with specific dream contents. Monitoring this posterior 'hot zone' in real time predicted whether an individual reported dreaming or the absence of dream experiences during NREM sleep, suggesting that it may constitute a core correlate of conscious experiences in sleep

SID 18 / Limitaciones del diseño plástico

En este trabajo el autor indica que todas las limitaciones tienden a hacer que la carga bajo la cual ocurre la falla estructural real sea más alta o más baja que la carga de falla rígido plástica

c ○ Copyright American Association for Artificial Intelligence (AAAI), www.aaai.org On the Origin of Environments by Means of Natural Selection ∗

The field of adaptive robotics involves simulations and real-world implementations of robots which adapt to their environments. In this paper we introduce adaptive environmentics—the flip side of adaptive robotics—in which the environment adapts to the robot. To illustrate the approach we offer three simple experiments in which a genetic algorithm is used to shape an environment for a simulated Khepera robot. We then discuss at length the potential of adaptive environmentics, also delineating several possible avenues of future research

Antibodies Targeting Human Endothelin-1 Receptors Reveal Different Conformational States in Cancer Cells

International audienceThe endothelin axis (endothelins and their receptors) is strongly involved in physiological and pathological processes. ET-1 plays a crucial role in particular in tumor diseases. Endothelin-1 receptors (ETA and ETB) are deregulated and overexpressed in several tumors such as melanoma and glioma. We studied the binding of 24 monoclonal antibodies directed against human ETB receptors (hETB) to different melanoma cell lines. Few of these mAbs bound to all the melanoma cell lines. One of them, rendomab B49, bound to ETB receptors expressed at the surface of human glioma stem cells. More recently, we produced new antibodies directed against human ETA receptor (hETA). Several antibodies have been isolated and have been screened on different tumoral cells lines. As for the mAbs directed against the hETB receptor only some of new antibodies directed against ETA receptor are capable to bind the human tumoral cell lines. Rendomab A63 directed against hETA is one of them. We report the specificity and binding properties of these mAbs and consider their potential use in diagnosis by an in vivo imaging approach

Étude de la voie des rétinoïdes au sein des membranes fœtales humaines : mise en évidence de gènes cibles

International audienceRetinoids (active derivatives of vitamin A) were already demonstrated to be important morphogenes and their implication at the placental and fetal level was already established. A new field of research is now developed in order to show their role on fetal membranes constituted by amnion and chorion. To describe the role of retinoids on these membranes, our studies were focused on target gene research. Firstly, all metabolism enzymes needed to vitamin A pathways were demonstrated to be present and active in signal transduction. Secondly, a bioinformatic analysis was performed to assess a list of potential target genes that could be classified in different biological pathways (inflammation, retinoids, hormones, vascularization, extracellular matrix and water homeostasis). Then, it was demonstrated that the gene coding for PLAT, implied in the degradation of extracellular matrix during programmed or premature rupture of membranes, is regulated by retinoids in a two steps mechanism. Finally, preliminary data showed that some aquaporins, which control water transport across membranes, are expressed and regulated by retinoids in the fetal membranes. A disregulation in pathologies like oligo or poly-hydramnios can be anticipated. Improvement of our knowledge about the retinoid implications is a key point in order to obtain a precise and complete documented cartography of the vitamin A (regulating) in amniotic membranes (regulated) that will permit the development of new diagnostic and therapeutic strategies