Something Old, Something New — Applying a Pre-trained Parsing Model to Clinical Swedish

Proceedings of the 18th Nordic Conference of Computational Linguistics NODALIDA 2011. Editors: Bolette Sandford Pedersen, Gunta Nešpore and Inguna Skadiņa. NEALT Proceedings Series, Vol. 11 (2011), 287-290. © 2011 The editors and contributors. Published by Northern European Association for Language Technology (NEALT) http://omilia.uio.no/nealt . Electronically published at Tartu University Library (Estonia) http://hdl.handle.net/10062/1695

Simulation of Networked Control Systems Using TrueTime

This paper gives a brief introduction to the TrueTime simulator and then gives several examples on how TrueTime can be used to simulate networked control systems. Among the examples are time-triggered and event-based networked control and AODV routing in wireless ad-hoc networks

Severity as a Priority Setting Criterion: Setting a Challenging Research Agenda

Priority setting in health care is ubiquitous and health authorities are increasingly recognising the need for priority setting guidelines to ensure efficient, fair, and equitable resource allocation. While cost-effectiveness concerns seem to dominate many policies, the tension between utilitarian and deontological concerns is salient to many, and various severity criteria appear to fill this gap. Severity, then, must be subjected to rigorous ethical and philosophical analysis. Here we first give a brief history of the path to today’s severity criteria in Norway and Sweden. The Scandinavian perspective on severity might be conducive to the international discussion, given its long-standing use as a priority setting criterion, despite having reached rather different conclusions so far. We then argue that severity can be viewed as a multidimensional concept, drawing on accounts of need, urgency, fairness, duty to save lives, and human dignity. Such concerns will often be relative to local mores, and the weighting placed on the various dimensions cannot be expected to be fixed. Thirdly, we present what we think are the most pertinent questions to answer about severity in order to facilitate decision making in the coming years of increased scarcity, and to further the understanding of underlying assumptions and values that go into these decisions. We conclude that severity is poorly understood, and that the topic needs substantial further inquiry; thus we hope this article may set a challenging and important research agenda

Simulation of Wireless Networked Control Systems

Embedded systems are becoming increasingly networked and are deployed in application areas that require close interaction with their physical environment. Examples include distributed mobile agents and wireless sensor/actuator networks. The complexity of these applications make co-simulation a necessary tool during system development. This paper presents a simulation environment that facilitates simulation of computer nodes and communication networks interacting with the continuous-time dynamics of the real world. Features of the simulator include interrupt handling, task scheduling, wired and wireless communication, local clocks, dynamic voltage scaling, and battery-driven operation. Two simulation case studies are presented: a simple communication scenario and a mobile robot soccer game

Gradients of anthropogenic stress in Indonesian coral reefs Implications for bacterial community composition and aggregate formation

The Indonesian Spermonde Archipelago, like other coral reefs located in close vicinity to urban areas, is confronted with a multitude of local anthropogenic stressors. A combination of experimental and observational studies was conducted at several fringing reefs and in the water column of the Archipelago during two sampling campaigns. Water quality parameters were not gradually decreasing with increasing distance from Makassar. Instead, there were two contrasting regions, one eutrophic inshore zone and the remaining, oligotrophic shelf. Bacterial community compositions were very distinct between those two described zones. Additionally, significantly higher total aggregated volume and sedimentation rates were observed in the eutrophic zone compared sampling within the oligotrophic outer shelf zone. Data presented in this thesis conclusively showed that dense human populations on the mainland and on the individual islands exerted a clear and measurable influence on the investigated water quality parameters, but that influence was restricted to a narrow zone close to the coast

Holistic Simulation of Mobile Robot and Sensor Network Applications Using TrueTime

The RUNES project defines a complex road tunnel scenario involving multiple mobile robots navigating in sensor network environment. In this paper, a TrueTime simulation model of the tunnel scenario is developed. The TrueTime simulator allows concurrent simulation of the physical robots and their environment, the software in the nodes, the radio communication, the network routing, and the ultra-sound navigation system. The various models are described in detail, and some simulation results obtained from the complete model are presented

High risk of in-breast tumor recurrence after BRCA1/2-associated breast cancer

The purpose of the study was to compare breast-conserving therapy (BCT) and mastectomy (M) in BRCA1/2 mutation carriers. Women with invasive breast cancer and a pathogenic mutation in BRCA1 or BRCA2 were included in the study (n = 162). Patients treated with BCT (n = 45) were compared with patients treated with M (n = 118). Endpoints were local recurrence as first recurrence (LR), overall survival (OS), breast cancer death, and distant recurrence. Cumulative incidence was calculated in the presence of competing risks. For calculation of hazard ratios and for multivariable analysis, cause-specific Cox proportional hazards regression was used. Compared to M, BCT was associated with an increased risk of LR in univariable analysis (HR 4.0; 95 % CI 1.6-9.8) and in multivariable analysis adjusting for tumor stage, age, and use of adjuvant chemotherapy (HR 2.9; CI 1.1-7.8). Following M, all local recurrences were seen in the first 5 years after breast cancer diagnosis. Following BCT, the rate of LR continued to be high also after the first 5 years. The cumulative incidence of LR in the BCT group was 15, 25, and 32 % after 5, 10, and 15 years, respectively. There were no significant differences between BCT and M for OS, breast cancer death, or distant recurrence. BRCA1/2 mutation carriers treated with BCT have a high risk of LR, many of which are new primary breast cancers. This must be thoroughly discussed with the patient and is an example of how rapid treatment-focused genetic testing could influence choice of treatment

High risk of in-breast tumor recurrence after BRCA1/2-associated breast cancer.

To access publisher's full text version of this article click on the hyperlink at the bottom of the pageThe purpose of the study was to compare breast-conserving therapy (BCT) and mastectomy (M) in BRCA1/2 mutation carriers. Women with invasive breast cancer and a pathogenic mutation in BRCA1 or BRCA2 were included in the study (n = 162). Patients treated with BCT (n = 45) were compared with patients treated with M (n = 118). Endpoints were local recurrence as first recurrence (LR), overall survival (OS), breast cancer death, and distant recurrence. Cumulative incidence was calculated in the presence of competing risks. For calculation of hazard ratios and for multivariable analysis, cause-specific Cox proportional hazards regression was used. Compared to M, BCT was associated with an increased risk of LR in univariable analysis (HR 4.0; 95 % CI 1.6-9.8) and in multivariable analysis adjusting for tumor stage, age, and use of adjuvant chemotherapy (HR 2.9; CI 1.1-7.8). Following M, all local recurrences were seen in the first 5 years after breast cancer diagnosis. Following BCT, the rate of LR continued to be high also after the first 5 years. The cumulative incidence of LR in the BCT group was 15, 25, and 32 % after 5, 10, and 15 years, respectively. There were no significant differences between BCT and M for OS, breast cancer death, or distant recurrence. BRCA1/2 mutation carriers treated with BCT have a high risk of LR, many of which are new primary breast cancers. This must be thoroughly discussed with the patient and is an example of how rapid treatment-focused genetic testing could influence choice of treatment.Regional Ethical Review Board in Lund Skane County Counsil's Research and Development Foundation Swedish Breast Cancer Association (BRO) Swedish Cancer Society BioCAR