59 research outputs found
Magnetic Field Stimulated Transitions of Excited States in Fast Muonic Helium Ions
It is shown that one can stimulate, by using the present-day laboratory
magnetic fields, transitions between the sub-levels of fast
ions formating in muon catalyzed fusion. Strong fields also cause the
self-ionization from highly excited states of such muonic ions. Both effects
are the consequence of the interaction of the bound muon with the oscillating
field of the Stark term coupling the center-of-mass and muon motions of the
ion due to the non-separability of the collective and internal
variables in this system. The performed calculations show a possibility to
drive the population of the sub-levels by applying a field of a few
, which affects the reactivation rate and is especially important to the
-ray production in muon catalyzed fusion. It is also shown that
the splitting in due to the vacuum polarization slightly
decreases the stimulated transition rates.Comment: 5 figure
Non-diffractive mechanisms in the meson photoproduction on nucleons
We examine the non-diffractive mechanisms in the meson photoproduction
from threshold up to a few GeV using an effective Lagrangian in a constituent
quark model. The new data from CLAS at large angles can be consistently
accounted for in terms of {\it s}- and {\it u}-channel processes. Isotopic
effects arising from the reactions and , are investigated by comparing the cross sections and polarized beam
asymmetries. Our result highlights an experimental means of studying
non-diffractive mechanisms in meson photoproduction.Comment: 4 eps figures, version accepted by Phys. Lett.
Population Monte Carlo algorithms
We give a cross-disciplinary survey on ``population'' Monte Carlo algorithms.
In these algorithms, a set of ``walkers'' or ``particles'' is used as a
representation of a high-dimensional vector. The computation is carried out by
a random walk and split/deletion of these objects. The algorithms are developed
in various fields in physics and statistical sciences and called by lots of
different terms -- ``quantum Monte Carlo'', ``transfer-matrix Monte Carlo'',
``Monte Carlo filter (particle filter)'',``sequential Monte Carlo'' and
``PERM'' etc. Here we discuss them in a coherent framework. We also touch on
related algorithms -- genetic algorithms and annealed importance sampling.Comment: Title is changed (Population-based Monte Carlo -> Population Monte
Carlo). A number of small but important corrections and additions. References
are also added. Original Version is read at 2000 Workshop on
Information-Based Induction Sciences (July 17-18, 2000, Syuzenji, Shizuoka,
Japan). No figure
Susceptibility and dilution effects of the kagome bi-layer geometrically frustrated network. A Ga-NMR study of SrCr_(9p)Ga_(12-9p)O_(19)
We present an extensive gallium NMR study of the geometrically frustrated
kagome bi-layer compound SrCr_(9p)Ga_(12-9p)O_(19) (Cr^3+, S=3/2) over a broad
Cr-concentration range (.72<p<.95). This allows us to probe locally the kagome
bi-layer susceptibility and separate the intrinsic properties due to the
geometric frustration from those related to the site dilution. Our major
findings are: 1) The intrinsic kagome bi-layer susceptibility exhibits a
maximum in temperature at 40-50 K and is robust to a dilution as high as ~20%.
The maximum reveals the development of short range antiferromagnetic
correlations; 2) At low-T, a highly dynamical state induces a strong wipe-out
of the NMR intensity, regardless of dilution; 3) The low-T upturn observed in
the macroscopic susceptibility is associated to paramagnetic defects which stem
from the dilution of the kagome bi-layer. The low-T analysis of the NMR
lineshape suggests that the defect can be associated with a staggered
spin-response to the vacancies on the kagome bi-layer. This, altogether with
the maximum in the kagome bi-layer susceptibility, is very similar to what is
observed in most low-dimensional antiferromagnetic correlated systems; 4) The
spin glass-like freezing observed at T_g=2-4 K is not driven by the
dilution-induced defects.Comment: 19 pages, 19 figures, revised version resubmitted to PRB Minor
modifications: Fig.11 and discussion in Sec.V on the NMR shif
Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362
Inhibitors of COP-mediated Transport and Cholera Toxin Action Inhibit Simian Virus 40 Infection
Simian virus 40 (SV40) is a nonenveloped virus that has been shown to pass from surface caveolae to the endoplasmic reticulum in an apparently novel infectious entry pathway. We now show that the initial entry step is blocked by brefeldin A and by incubation at 20degreesC. Subsequent to the entry step, the virus reaches a domain of the rough endoplasmic reticulum by an unknown pathway. This intracellular trafficking pathway is also brefeldin A sensitive. Infection is strongly inhibited by expression of GTP-restricted ADP-ribosylation factor 1 (Arf1) and Sar1 mutants and by microinjection of antibodies to betaCOP. In addition, we demonstrate a potent inhibition of SV40 infection by the dipeptide N-benzoyl-oxycarbonyl-Gly-Phe-amide, which also inhibits late events in cholera toxin action. Our results identify novel inhibitors of SV40 infection and show that SV40 requires COPI- and COPII-dependent transport steps for successful infection
The Galactic Environment of the Sun: Interstellar Material Inside and Outside of the Heliosphere
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