454 research outputs found

    Implementing 5D BIM on construction projects: Contractor perspectives from the UK construction sector

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    This is an accepted manuscript of an article published by Emerald in Journal of Engineering, Design and Technology on 09/05/2020: https://doi.org/10.1108/JEDT-01-2020-0007 The accepted version of the publication may differ from the final published version.Purpose The purpose of this paper is to report on primary research findings that sought to investigate and analyse salient issues on the implementation of 5D building information modelling (BIM) from the UK contractors’ perspective. Previous research and efforts have predominantly focussed on the use of technologies for cost estimation and quantity takeoff within a more traditional-led procurement, with a paucity of research focussing on how 5D BIM could facilitate costing within contractor-led procurement. This study fills this current knowledge gap and enhances the understanding of the specific costing challenges faced by contractors in contractor-led projects, leading to the development of 5D framework for use in future projects. Design/methodology/approach To develop a fully detailed understanding of the challenges and issues being faced in this regard, a phenomenological, qualitative-based study was undertaken through interviews involving 21 participants from UK-wide construction organisations. A thematic data analytical process was applied to the data to derive key issues, and this was then used to inform the development of a 5D-BIM costing framework. Findings Multi-disciplinary findings reveal a range of issues faced by contractors when implementing 5D BIM. These exist at strategic, operational and technological levels which require addressing successful implementation of 5D BIM on contractor-led projects adhering to Level 2 BIM standards. These findings cut across the range of stakeholders on contractor-led projects. Ultimately, the findings suggest strong commitment and leadership from organisational management are required to facilitate cost savings and generate accurate cost information. Practical implications This study highlights key issues for any party seeking to effectively deploy 5D BIM on a contractor-led construction project. A considerable cultural shift towards automating and digitising cost functions virtually, stronger collaborative working relationship relative to costing in design development, construction practice, maintenance and operation is required. Originality/value By analysing findings from primary research data, the work concludes with the development of a 5D BIM costing framework to support contractor-led projects which can be implemented to ensure that 5D BIM is successfully implemented

    Artificial neural network analysis of teachers��� performance against thermal comfort

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    This is an accepted manuscript of an article published by Emerald in International Journal of Building Pathology and Adaptation on 17/04/2020, available online at: https://doi.org/10.1108/IJBPA-11-2019-0098 The accepted manuscript may differ from the final published version.Purpose: The impact of thermal comfort in educational buildings continues to be of major importance in both the design and construction phases. Given this, it is also equally important to understand and appreciate the impact of design decisions on post-occupancy performance, particularly on staff and students. This study aims to present the effect of IEQ on teachers��� performance. This study would provide thermal environment requirements to BIM-led school refurbishment projects. Design: This paper presents a detailed investigation into the direct impact of thermal parameters (temperature, relative humidity and ventilation rates) on teacher performance. In doing so, the research methodological approach combines explicit mixed-methods using questionnaire surveys and physical measurements of thermal parameters to identify correlation and inference. It was conducted through a single case study using a technical college based in Saudi Arabia. Findings: Findings from this work were used to develop a model using an Artificial Neural Network to establish causal relationships. Research findings indicate an optimal temperature range between 23��C and 25��C, with a 65% relative humidity and 0.4m/s ventilation rate. This ratio delivered optimum results for both comfort and performance

    Purification and characterisation of an insulin-stimulated protein-serine kinase which phosphorylates acetyl-CoA carboxylase

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    AbstractAn insulin-stimulated protein kinase specific for acetyl-CoA carboxylase has been purified from rat epididymal adipose tissue using Mono-Q chromatography. The kinase binds to (and phosphorylates) the relatively inactive, dimeric form of acetyl-CoA carboxylase, but not to its active, polymeric form, and this property has been used to purify the kinase. Under the conditions used, phosphorylation by the purified kinase did not result in a detectable increase in acetyl-CoA carboxylase activity. These studies also led to the recognition of an `activator' protein which is capable of increasing the activity of acetyl-CoA carboxylase without changing its phosphorylation state. It is suggested that this `activator' protein, together with the insulin-activated acetyl-CoA carboxylase kinase, may play a role in the activation of acetyl-CoA carboxylase by insulin

    Identification of Epstein-Barr virus replication proteins in Burkitt’s lymphoma cells

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    The working model to describe the mechanisms used to replicate the cancer-associated virus Epstein-Barr virus (EBV) is partly derived from comparisons with other members of the Herpes virus family. Many genes within the EBV genome are homologous across the herpes virus family. Published transcriptome data for the EBV genome during its lytic replication cycle show extensive transcription, but the identification of the proteins is limited. We have taken a global proteomics approach to identify viral proteins that are expressed during the EBV lytic replication cycle. We combined an enrichment method to isolate cells undergoing EBV lytic replication with SILAC-labeling coupled to mass-spectrometry and identified viral and host proteins expressed during the OPEN ACCESS Pathogens 2015, 4 740 EBV lytic replication cycle. Amongst the most frequently identified viral proteins are two components of the DNA replication machinery, the single strand DNA binding protein BALF2, DNA polymerase accessory protein BMRF1 and both subunits of the viral ribonucleoside-diphosphate reductase enzyme (BORF2 and BaRF1). An additional 42 EBV lytic cycle proteins were also detected. This provides proteomic identification for many EBV lytic replication cycle proteins and also identifies post-translational modifications

    Building Information Management (BIM) Education in the Dominican Republic: An Empirical Study

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    Building Information Management (BIM) education is par excellence the best solution to overcome the lack of BIM knowledge and BIM skilled professionals that affect the implementation of BIM in the Architecture, Engineering, and Construction (AEC) industry. Moreover, BIM education is vital to drive the implementation and evolution of BIM in the AEC industry. However, its provision can be a difficult task, more for BIM infant countries such as the Dominican Republic (DR). By adopting a qualitative approach, using semi‐structured interviews with nine professionals involved in BIM education, this study aims to explore the presence of BIM education in the DR. The data gathered was analysed with the method of content analysis. The findings mainly indicated: a shortage of BIM experts; lack of BIM education, as there is currently provided only BIM training based on software; and the dissemination of BIM knowledge through educational activities and BIM communities. However, the provision of BIM education is likely to expand. Most of the current training providers are eager to continue with their work and get into further areas, and there is also evidence of the first plan of inserting BIM in a university curriculum. These results infer that, for an infant country, BIM education seems to be heading in the right direction in the DR. The implementation of BIM is likely to increase, along with the provision and demand of BIM education in the country. This research may be beneficial to professional and policy makers interested in BIM education in BIM infant countries
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