98 research outputs found
Genetic engineering of E-coli SE5000 and its potential for Ni2+ bioremediation
A genetically engineered Escherichia coli SE5000 strain simultaneously expressing nickel transport system and metallothionein was constructed to accumulate Ni2+ from aqueous solution. Bioaccumulation was fast and followed linearized Langmuir isotherm. Compared with 1.62 mg/g of Ni2+ uptake capacity by original host E. coli cells, genetically engineered E. coli could bind 7.14 mg/g Ni2+, and it accumulated Ni2+ effectively over a broad range of pH (4-10) and the optimal pH was 8.6. The presence of 1000mg/l Na+ and Ca2+ or 50 mg/l Cd2+ and Pb2+ did not decrease Ni2+ bioaccumulation significantly, but Mg2+, Hg2+, Cr3+ and Cu2+ posed severe deleterious influences on Ni2+ uptake by genetically engineered E. coli. Furthermore, the presence of EDTA inhibited nickel bioaccumulation. (C) 2004 Elsevier Ltd. All rights reserved
Measurement of Trace I-129 Concentrations in CsI Powder and Organic Liquid Scintillator with Accelerator Mass Spectrometry
Levels of trace radiopurity in active detector materials is a subject of
major concern in low-background experiments. Procedures were devised to measure
trace concentrations of I-129 in the inorganic salt CsI as well as in organic
liquid scintillator with Accelerator Mass Spectrometry (AMS) which leads to
improvement in sensitivities by several orders of magnitude over other methods.
No evidence of their existence in these materials were observed. Limits of < 6
X 10^{-13} g/g and < 2.6 X 10^{-17} g/g on the contaminations of I-129 in CsI
and liquid scintillator, respectively, were derived.These are the first results
in a research program whose goals are to develop techniques to measure trace
radioactivity in detector materials by AMS.Comment: Proceedings of 10th International Conference on Accelerator Mass
Spectrometr
RQM description of the charge form factor of the pion and its asymptotic behavior
The pion charge and scalar form factors, and , are first
calculated in different forms of relativistic quantum mechanics. This is done
using the solution of a mass operator that contains both confinement and
one-gluon-exchange interactions. Results of calculations, based on a one-body
current, are compared to experiment for the first one. As it could be expected,
those point-form, and instant and front-form ones in a parallel momentum
configuration fail to reproduce experiment. The other results corresponding to
a perpendicular momentum configuration (instant form in the Breit frame and
front form with ) do much better. The comparison of charge and scalar
form factors shows that the spin-1/2 nature of the constituents plays an
important role. Taking into account that only the last set of results
represents a reasonable basis for improving the description of the charge form
factor, this one is then discussed with regard to the asymptotic QCD-power-law
behavior . The contribution of two-body currents in achieving the right
power law is considered while the scalar form factor, , is shown to
have the right power-law behavior in any case. The low- behavior of the
charge form factor and the pion-decay constant are also discussed.}Comment: 30 pages, 10 figure
Study of five quark system with three kinds of quark-quark hyperfine interaction
The low-lying energy spectra of five quark systems (I=1/2, S=0)
and (I=0, S=-1) are investigated with three kinds of schematic
interactions: the chromomagnetic interaction, the flavor-spin dependent
interaction and the instanton-induced interaction. In all the three models, the
lowest five quark state ( or ) has an orbital angular
momentum L=0 and the spin-parity ; the mass of the lowest
state is heavier than the lowest state
High Altitude test of RPCs for the ARGO-YBJ experiment
A 50 m**2 RPC carpet was operated at the YangBaJing Cosmic Ray Laboratory
(Tibet) located 4300 m a.s.l. The performance of RPCs in detecting Extensive
Air Showers was studied. Efficiency and time resolution measurements at the
pressure and temperature conditions typical of high mountain laboratories, are
reported.Comment: 16 pages, 10 figures, submitted to Nucl. Instr. Met
The ARGO-YBJ Experiment Progresses and Future Extension
Gamma ray source detection above 30TeV is an encouraging approach for finding
galactic cosmic ray origins. All sky survey for gamma ray sources using wide
field of view detector is essential for population accumulation for various
types of sources above 100GeV. To target the goals, the ARGO-YBJ experiment has
been established. Significant progresses have been made in the experiment. A
large air shower detector array in an area of 1km2 is proposed to boost the
sensitivity. Hybrid detection with multi-techniques will allow a good
discrimination between different types of primary particles, including photons
and protons, thus enable an energy spectrum measurement for individual specie.
Fluorescence light detector array will extend the spectrum measurement above
100PeV where the second knee is located. An energy scale determined by balloon
experiments at 10TeV will be propagated to ultra high energy cosmic ray
experiments
ARGO-YBJ constraints on very high energy emission from GRBs
The ARGO-YBJ (Astrophysical Radiation Ground-based Observatory at YangBaJing)
experiment is designed for very high energy -astronomy and cosmic ray
researches. Due to the full coverage of a large area () with
resistive plate chambers at a very high altitude (4300 m a.s.l.), the ARGO-YBJ
detector is used to search for transient phenomena, such as Gamma-ray bursts
(GRBs). Because the ARGO-YBJ detector has a large field of view (2 sr)
and is operated with a high duty cycle (90%), it is well suited for GRB
surveying and can be operated in searches for high energy GRBs following alarms
set by satellite-borne observations at lower energies. In this paper, the
sensitivity of the ARGO-YBJ detector for GRB detection is estimated. Upper
limits to fluence with 99% confidence level for 26 GRBs inside the field of
view from June 2006 to January 2009 are set in the two energy ranges 10100
GeV and 10 GeV1 TeV.Comment: accepted for publication in Astroparticle Physic
The trans-ancestral genomic architecture of glycemic traits
Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date, most genetic studies of glycemic traits have focused on individuals of European ancestry. Here we aggregated genome-wide association studies comprising up to 281,416 individuals without diabetes (30% non-European ancestry) for whom fasting glucose, 2-h glucose after an oral glucose challenge, glycated hemoglobin and fasting insulin data were available. Trans-ancestry and single-ancestry meta-analyses identified 242 loci (99 novel; P < 5 x 10(-8)), 80% of which had no significant evidence of between-ancestry heterogeneity. Analyses restricted to individuals of European ancestry with equivalent sample size would have led to 24 fewer new loci. Compared with single-ancestry analyses, equivalent-sized trans-ancestry fine-mapping reduced the number of estimated variants in 99% credible sets by a median of 37.5%. Genomic-feature, gene-expression and gene-set analyses revealed distinct biological signatures for each trait, highlighting different underlying biological pathways. Our results increase our understanding of diabetes pathophysiology by using trans-ancestry studies for improved power and resolution.A trans-ancestry meta-analysis of GWAS of glycemic traits in up to 281,416 individuals identifies 99 novel loci, of which one quarter was found due to the multi-ancestry approach, which also improves fine-mapping of credible variant sets.Diabetes mellitus: pathophysiological changes and therap
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