The contributions of interpersonal attachment and friendship group identification to depressive symptoms in a non-clinical sample:Attachment, group identification, and depression

Drawing on previous literature from the separate areas of adult attachment and group processes, we explored attachment and group identification as predictors for depressive symptoms in a nonclinical sample.We found that attachment anxiety and friendship group identification predicted scores on the Beck Depression Inventory, such that higher attachment anxiety resulted in higher depressive symptoms, and greater friendship group identification resulted in lower depressive symptoms. Mediational analysis suggested that group identification partially mediated the effect of attachment avoidance on depressive symptoms, but did not mediate the effect of attachment anxiety on depressive symptoms

Threat, prejudice and stereotyping in the context of Japanese, North Korean, and South Korean intergroup relations

ABSTRACT Integrate

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

CD25 is expressed at high levels on regulatory T (Treg) cells and was initially proposed as a target for cancer immunotherapy. However, anti-CD25 antibodies have displayed limited activity against established tumors. We demonstrated that CD25 expression is largely restricted to tumor-infiltrating Treg cells in mice and humans. While existing anti-CD25 antibodies were observed to deplete Treg cells in the periphery, upregulation of the inhibitory Fc gamma receptor (FcγR) IIb at the tumor site prevented intra-tumoral Treg cell depletion, which may underlie the lack of anti-tumor activity previously observed in pre-clinical models. Use of an anti-CD25 antibody with enhanced binding to activating FcγRs led to effective depletion of tumor-infiltrating Treg cells, increased effector to Treg cell ratios, and improved control of established tumors. Combination with anti-programmed cell death protein-1 antibodies promoted complete tumor rejection, demonstrating the relevance of CD25 as a therapeutic target and promising substrate for future combination approaches in immune-oncology

Threat, prejudice and stereotyping in the context of Japanese, North Korean, and South Korean intergroup relations.

Integrated threat theory, realistic conflict theory, and group justification (based on social identity theory) were evaluated in the international context of Japanese prejudice toward North Korea and South Korea. Military threat emerged as an important addition to the four threats outlined by integrated threat theory. Three perceived North Korean threats (realistic [domestic] threat; intergroup anxiety; military threat) predicted prejudice toward North Korea. North Korean prejudice predicted negative stereotypes, supporting group-justification theory. Perceived North Korean realistic [domestic] threat predicted prejudice toward South Korea. Prejudice toward South Korea predicted negative stereotypes of North Korea, suggesting a mechanism by which prejudice generalizes

The Valence of Self-Generated (Status Updates) and Other-Generated (Wall-Posts) Information Determines Impression Formation on Facebook

We examined whether self-generated (status updates) or other-generated (wall-posts) information on Facebook influenced the impression formed of the target individual. Along with examining reliance on particular types of information, we explored the valence (positive/ neutral/ negative) of the information, as reliance on self-generated or other-generated information may depend on whether self-presentation is perceived (i.e., presenting oneself positively / not negatively). Self-presentation may be perceived if the targets have positive/ neutral statuses, while negative statuses would indicate a lack of self-presentation. In line with previous research, participants should rely on other-generated information (wall-posts) to form an impression when participants are viewed to have self-presented (positive / neutral status updates), as this information could be viewed as unreliable. Forty participants rated nine Facebook profiles where statuses and wall-posts portrayed personality traits varying in valence. Each profile consisted of a neutral profile photo, three status updates (all positive, negative, or neutral) and three wall-posts (all positive, negative, or neutral). Materials were established in two pilots. Impression formation was measured as perceived social, task, and physical attractiveness of the target individual. Participants also ranked the profiles for likeability. Supporting our expectations, other-generated information (wall-posts) dominated impression formation for social attractiveness when self-generated information (status updates) was positive/ neutral. Task attractiveness was affected by information valence, regardless of source (self or other). Despite the inclusion of neutral photos, physical attractiveness was affected by self-generated information, with negative statuses lowering physical attractiveness. We suggest that these findings have implications for impression formation beyond the Facebook setting. The 557 traits analyzed in Pilot 1 are available as supporting information (S1 Dataset) and may be useful for other impression formation researchers

Interpersonal Attraction.

<p>Profiles ordered by mean social attractiveness, mean physical attractiveness, and mean task attractiveness.</p><p>Interpersonal Attraction.</p

Ranked Likeability.

<p>Means and SD for the ranked likability of each profile (1 = most likeable; 9 = least likeable), including the median rank, and minimum to maximum rank.</p><p>Ranked Likeability.</p

Statuses and wall posts (trait in bold).

<p>Statuses and wall posts (trait in bold).</p