1,765 research outputs found
A comprehensive evaluation of colonic mucosal isolates of Sutterella wadsworthensis from inflammatory bowel disease
Peer reviewedPublisher PD
Intercomparison of the northern hemisphere winter mid-latitude atmospheric variability of the IPCC models
We compare, for the overlapping time frame 1962-2000, the estimate of the
northern hemisphere (NH) mid-latitude winter atmospheric variability within the
XX century simulations of 17 global climate models (GCMs) included in the
IPCC-4AR with the NCEP and ECMWF reanalyses. We compute the Hayashi spectra of
the 500hPa geopotential height fields and introduce an integral measure of the
variability observed in the NH on different spectral sub-domains. Only two
high-resolution GCMs have a good agreement with reanalyses. Large biases, in
most cases larger than 20%, are found between the wave climatologies of most
GCMs and the reanalyses, with a relative span of around 50%. The travelling
baroclinic waves are usually overestimated, while the planetary waves are
usually underestimated, in agreement with previous studies performed on global
weather forecasting models. When comparing the results of various versions of
similar GCMs, it is clear that in some cases the vertical resolution of the
atmosphere and, somewhat unexpectedly, of the adopted ocean model seem to be
critical in determining the agreement with the reanalyses. The GCMs ensemble is
biased with respect to the reanalyses but is comparable to the best 5 GCMs.
This study suggests serious caveats with respect to the ability of most of the
presently available GCMs in representing the statistics of the global scale
atmospheric dynamics of the present climate and, a fortiori, in the perspective
of modelling climate change.Comment: 39 pages, 8 figures, 2 table
Climate Dynamics: A Network-Based Approach for the Analysis of Global Precipitation
Precipitation is one of the most important meteorological variables for defining the climate dynamics, but the spatial patterns of precipitation have not been fully investigated yet. The complex network theory, which provides a robust tool to investigate the statistical interdependence of many interacting elements, is used here to analyze the spatial dynamics of annual precipitation over seventy years (1941-2010). The precipitation network is built associating a node to a geographical region, which has a temporal distribution of precipitation, and identifying possible links among nodes through the correlation function. The precipitation network reveals significant spatial variability with barely connected regions, as Eastern China and Japan, and highly connected regions, such as the African Sahel, Eastern Australia and, to a lesser extent, Northern Europe. Sahel and Eastern Australia are remarkably dry regions, where low amounts of rainfall are uniformly distributed on continental scales and small-scale extreme events are rare. As a consequence, the precipitation gradient is low, making these regions well connected on a large spatial scale. On the contrary, the Asiatic South-East is often reached by extreme events such as monsoons, tropical cyclones and heat waves, which can all contribute to reduce the correlation to the short-range scale only. Some patterns emerging between mid-latitude and tropical regions suggest a possible impact of the propagation of planetary waves on precipitation at a global scale. Other links can be qualitatively associated to the atmospheric and oceanic circulation. To analyze the sensitivity of the network to the physical closeness of the nodes, short-term connections are broken. The African Sahel, Eastern Australia and Northern Europe regions again appear as the supernodes of the network, confirming furthermore their long-range connection structure. Almost all North-American and Asian nodes vanish, revealing that extreme events can enhance high precipitation gradients, leading to a systematic absence of long-range patterns
PainDroid: An android-based virtual reality application for pain assessment
Earlier studies in the field of pain research suggest that little efficient intervention currently exists in response to the exponential increase in the prevalence of pain. In this paper, we present an Android application (PainDroid) with multimodal functionality that could be enhanced with Virtual Reality (VR) technology, which has been designed for the purpose of improving the assessment of this notoriously difficult medical concern. Pain- Droid has been evaluated for its usability and acceptability with a pilot group of potential users and clinicians, with initial results suggesting that it can be an effective and usable tool for improving the assessment of pain. Participant experiences indicated that the application was easy to use and the potential of the application was similarly appreciated by the clinicians involved in the evaluation. Our findings may be of considerable interest to healthcare providers, policy makers, and other parties that might be actively involved in the area of pain and VR research
ARPES: A probe of electronic correlations
Angle-resolved photoemission spectroscopy (ARPES) is one of the most direct
methods of studying the electronic structure of solids. By measuring the
kinetic energy and angular distribution of the electrons photoemitted from a
sample illuminated with sufficiently high-energy radiation, one can gain
information on both the energy and momentum of the electrons propagating inside
a material. This is of vital importance in elucidating the connection between
electronic, magnetic, and chemical structure of solids, in particular for those
complex systems which cannot be appropriately described within the
independent-particle picture. Among the various classes of complex systems, of
great interest are the transition metal oxides, which have been at the center
stage in condensed matter physics for the last four decades. Following a
general introduction to the topic, we will lay the theoretical basis needed to
understand the pivotal role of ARPES in the study of such systems. After a
brief overview on the state-of-the-art capabilities of the technique, we will
review some of the most interesting and relevant case studies of the novel
physics revealed by ARPES in 3d-, 4d- and 5d-based oxides.Comment: Chapter to appear in "Strongly Correlated Systems: Experimental
Techniques", edited by A. Avella and F. Mancini, Springer Series in
Solid-State Sciences (2013). A high-resolution version can be found at:
http://www.phas.ubc.ca/~quantmat/ARPES/PUBLICATIONS/Reviews/ARPES_Springer.pdf.
arXiv admin note: text overlap with arXiv:cond-mat/0307085,
arXiv:cond-mat/020850
Collective Excitations of Holographic Quantum Liquids in a Magnetic Field
We use holography to study N=4 supersymmetric SU(Nc) Yang-Mills theory in the
large-Nc and large-coupling limits coupled to a number Nf << Nc of
(n+1)-dimensional massless supersymmetric hypermultiplets in the Nc
representation of SU(Nc), with n=2,3. We introduce a temperature T, a baryon
number chemical potential mu, and a baryon number magnetic field B, and work in
a regime with mu >> T,\sqrt{B}. We study the collective excitations of these
holographic quantum liquids by computing the poles in the retarded Green's
function of the baryon number charge density operator and the associated peaks
in the spectral function. We focus on the evolution of the collective
excitations as we increase the frequency relative to T, i.e. the
hydrodynamic/collisionless crossover. We find that for all B, at low
frequencies the tallest peak in the spectral function is associated with
hydrodynamic charge diffusion. At high frequencies the tallest peak is
associated with a sound mode similar to the zero sound mode in the
collisionless regime of a Landau Fermi liquid. The sound mode has a gap
proportional to B, and as a result for intermediate frequencies and for B
sufficiently large compared to T the spectral function is strongly suppressed.
We find that the hydrodynamic/collisionless crossover occurs at a frequency
that is approximately B-independent.Comment: 45 pages, 8 png and 47 pdf images in 22 figure
Streaming fragment assignment for real-time analysis of sequencing experiments
We present eXpress, a software package for efficient probabilistic assignment of ambiguously mapping sequenced fragments. eXpress uses a streaming algorithm with linear run time and constant memory use. It can determine abundances of sequenced molecules in real time and can be applied to ChIP-seq, metagenomics and other large-scale sequencing data. We demonstrate its use on RNA-seq data and show that eXpress achieves greater efficiency than other quantification methods
Intestinal parasitic infections in schoolchildren in different settings of Côte d'Ivoire : effect of diagnostic approach and implications for control
BACKGROUND: Social-ecological systems govern parasitic infections in humans. Within the frame of assessing the accuracy of a rapid diagnostic test for Schistosoma mansoni in Cote d'Ivoire, three different endemicity settings had to be identified and schoolchildren's intestinal parasitic infection profiles were characterized.
METHODS: In September 2010, a rapid screening was conducted in 11 schools in the Azaguie district, south Cote d'Ivoire. In each school, 25 children were examined for S. mansoni and S. haematobium. Based on predefined schistosome endemicity levels, three settings were selected, where schoolchildren aged 8-12 years were asked to provide three stool and three urine samples for an in-depth appraisal of parasitic infections. Triplicate Kato-Katz thick smears were prepared from each stool sample for S. mansoni and soil-transmitted helminth diagnosis, whereas urine samples were subjected to a filtration method for S. haematobium diagnosis. Additionally, a formol-ether concentration method was employed on one stool sample for the diagnosis of helminths and intestinal protozoa. Multivariable logistic regression models were employed to analyse associations between schoolchildren's parasitic infections, age, sex and study setting.
RESULTS: The prevalences of S. mansoni and S. haematobium infections in the initial screening ranged from nil to 88% and from nil to 56%, respectively. The rapid screening in the three selected areas revealed prevalences of S. mansoni of 16%, 33% and 78%. Based on a more rigorous diagnostic approach, the respective prevalences increased to 92%, 53% and 33%. S. haematobium prevalences were 0.8%, 4% and 65%. Prevalence and intensity of Schistosoma spp., soil-transmitted helminths and intestinal protozoan infections showed setting-specific patterns. Infections with two or more species concurrently were most common in the rural setting (84%), followed by the peri-urban (28.3%) and urban setting (18.2%).
CONCLUSIONS: More sensitive diagnostic tools or rigorous sampling approaches are needed to select endemicity settings with high fidelity. The observed small-scale heterogeneity of helminths and intestinal protozoan infections has important implications for contro
Combustion in thermonuclear supernova explosions
Type Ia supernovae are associated with thermonuclear explosions of white
dwarf stars. Combustion processes convert material in nuclear reactions and
release the energy required to explode the stars. At the same time, they
produce the radioactive species that power radiation and give rise to the
formation of the observables. Therefore, the physical mechanism of the
combustion processes, as reviewed here, is the key to understand these
astrophysical events. Theory establishes two distinct modes of propagation for
combustion fronts: subsonic deflagrations and supersonic detonations. Both are
assumed to play an important role in thermonuclear supernovae. The physical
nature and theoretical models of deflagrations and detonations are discussed
together with numerical implementations. A particular challenge arises due to
the wide range of spatial scales involved in these phenomena. Neither the
combustion waves nor their interaction with fluid flow and instabilities can be
directly resolved in simulations. Substantial modeling effort is required to
consistently capture such effects and the corresponding techniques are
discussed in detail. They form the basis of modern multidimensional
hydrodynamical simulations of thermonuclear supernova explosions. The problem
of deflagration-to-detonation transitions in thermonuclear supernova explosions
is briefly mentioned.Comment: Author version of chapter for 'Handbook of Supernovae,' edited by A.
Alsabti and P. Murdin, Springer. 24 pages, 4 figure
Transport phenomena in electrolyte solutions: Non-equilibrium thermodynamics and statistical mechanics
The theory of transport phenomena in multicomponent electrolyte solutions is
presented here through the integration of continuum mechanics,
electromagnetism, and non-equilibrium thermodynamics. The governing equations
of irreversible thermodynamics, including balance laws, Maxwell's equations,
internal entropy production, and linear laws relating the thermodynamic forces
and fluxes, are derived. Green-Kubo relations for the transport coefficients
connecting electrochemical potential gradients and diffusive fluxes are
obtained in terms of the flux-flux time correlations. The relationship between
the derived transport coefficients and those of the Stefan-Maxwell and
infinitely dilute frameworks are presented, and the connection between the
transport matrix and experimentally measurable quantities is described. To
exemplify application of the derived Green-Kubo relations in molecular
simulations, the matrix of transport coefficients for lithium and chloride ions
in dimethyl sulfoxide is computed using classical molecular dynamics and
compared with experimental measurements.Comment: fixed typos, added references, addressed comment
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