Got Caries? Breast milk and Early Childhood Caries?

Objective: To provide an analysis of the association between the longevity of breastfeeding and development of ECC. Determine the optimal time frame in which mothers should cease breastfeeding to reduce ECC development. Methods: Dr. Brickhouse, PubMed, Google Scholar and other scholarly databases were utilized to find current scientific evidence on the effects of breast milk on ECC. Relevant articles were summarized to write a review of literature. 16 articles published from 2015 to the present date were reviewed and cited. Results: From the studies, there is strong evidence to support breastfeeding beyond 12 months of age increases the prevalence of ECC. Furthermore, increased frequency and duration of breastfeeding leads to higher incidence of ECC. Conclusion: Findings indicate dental health care providers should recommend either ceasing breastfeeding at 12 months of age or provide ECC prevention education to caregivers. Further research is required to minimize data discrepancies between US and international countries.https://scholarscompass.vcu.edu/denh_student/1002/thumbnail.jp

“So what about the stories?” An exploratory study of the definition, use, and function of narrative child sexual exploitation material (N-CSEM)

The legal and psychological research surrounding online Child Sexual Exploitation Material (CSEM) is focused on visual depictions of children, either as still images or movies. Narrative CSEM (N-CSEM) describes an under-researched area, resulting from difficulties surrounding its conceptualisation, both legally as well as concerning the function for its users. The current study describes an initial attempt in defining N-CSEM in comparison to visual material, based on interviews with users of CSEM and N-CSEM and professionals working with this user group. Thematic Analysis resulted in three super-ordinate themes. All themes were analysed and enriched from the perspectives of user- and service-representatives. The study provides insight into N-CSEM as a separate entity from visual CSEM, challenging and informing legal decision-making and assessment and treatment providers for users of CSEM

Water Quality Trading and Offset Initiatives in the U.S.: A Comprehensive Survey

This document summarizes water quality trading and offset initiatives in the United States, including state-wide policies and recent proposals. The following format was used to present information on each program. We attempted to have each program summary reviewed by at least one contact person for program accuracy. In the cases where this review occurred, we added the statement "Reviewed by.." at the end of the case summary

How and why do social entrepreneurs experience goal conflict differently?

It is well-known that the need for both social and financial missions creates tension within social enterprises. Less well-known are the specifics around how and why social entrepreneurs themselves construct and experience their situation. Given people vary in their psychological representations of their goals from concrete (i.e., tasks) to more abstract (i.e., values), we anticipated that goal conflict with engaging in financial activities could vary along these lines, leading to potentially different solutions for support. Through collecting interviews and focus group data using goal hierarchies from 37 social entrepreneurs, we find six constructed realities with different salient goals at different levels of cognitive abstraction which either dictate, conflict with, or are dissociated from financial activities. These can explain why social entrepreneurs perceive their financial activities differently – financial activities as out of sight out of mind, aversive, a ball to juggle, a necessary evil, part and parcel, and as king - which are associated with four experiences of goal conflict (i.e., goal conflict as continual questioning, inevitable, manageable, and irrelevant).Publisher PDFPeer reviewe

Developing AFM Techniques for Testing PEG Hydrogels

Many instruments are used to find elastic properties of biological samples using methods such as tensile and bending tests, but using the atomic force microscope (AFM) is considered a non-destructive method because it can provide repeated local stiffness information without damaging the sample. It additionally allows the sample to be tested in an aqueous environment, which is optimal for soft materials such as hydrogels. The nanoindentation is performed via cantilever, measuring the deflection of the cantilever during the contact of the sample using a laser. Compared to hard samples, testing soft materials can present more challenges when working with the AFM, creating the need for a refined technique.[1] This study will explore ways to improve the accuracy and feasibility of testing hydrogels, which are significant in biomaterials research as they offer the ability to be altered mechanically and chemically to fit the needs of cells.[2] The technique for testing the hydrogels will be refined through a process moving from dry to wet samples, attempting to repeatedly and successfully obtain topography and elastic properties through high resolution topography scans and force curves. References: Radmacher, M., Tillamnn, R.W., Fritz, M., and Gaub, H.E. (1992), From molecules to cells: imaging soft samples with the atomic force microscope. Science. 257: 1900-1905 Flake, M. M., Nguyen, P. K., Scott, R. A., Vandiver, L. R., Willits, R. K., and Elbert, D. L. Poly(ethylene glycol) microparticles produced by precipitation polymerization in aqueous solution. Biomacromolecules 12 (844-850). 2011

Diversifying Knowledge: Presenting and Applying a Framework for Inclusive Graduate Program Websites

This paper reports our experience improving the inclusivity of Utah State University’s (USU) Technical Communication and Rhetoric (TCR) graduate program’s online materials. We report outcomes and implications of a 20-hour project in which Stevens applies aspects of an analytical framework developed by Alexander. In addition to the nine-tactic framework introduced in this report, readers may find value in four takeaways we share, based on our experience applying the framework

What is the most useful approach for forecasting hydrological extremes during El Niño?

In the past, efforts to prepare for the impacts of El Niño-driven flood and drought hazards have often relied on seasonal precipitation forecasts as a proxy for hydrological extremes, due to a lack of hydrologically relevant information. However, precipitation forecasts are not the best indicator of hydrological extremes. Now, two different global scale hydro-meteorological approaches for predicting river flow extremes are available to support flood and drought preparedness. These approaches are statistical forecasts based on large-scale climate variability and teleconnections, and resource-intensive dynamical forecasts using coupled ocean-atmosphere general circulation models. Both have the potential to provide early warning information, and both are used to prepare for El Niño impacts, but which approach provides the most useful forecasts? This study uses river flow observations to assess and compare the ability of two recently-developed forecasts to predict high and low river flow during El Niño: statistical historical probabilities of ENSO-driven hydrological extremes, and the dynamical seasonal river flow outlook of the Global Flood Awareness System (GloFAS-Seasonal). Our findings highlight regions of the globe where each forecast is (or is not) skilful compared to a forecast of climatology, and the advantages and disadvantages of each forecasting approach. We conclude that in regions where extreme river flow is predominantly driven by El Niño, or in regions where GloFAS-Seasonal currently lacks skill, the historical probabilities generally provide a more useful forecast. In areas where other teleconnections also impact river flow, with the effect of strengthening, mitigating or even reversing the influence of El Niño, GloFAS-Seasonal forecasts are typically more useful

Interactions of the Gasotransmitters Contribute to Microvascular Tone (Dys)regulation in the Preterm Neonate

Background & Aims Hydrogen sulphide (H2S), nitric oxide (NO), and carbon monoxide (CO) are involved in transitional microvascular tone dysregulation in the preterm infant; however there is conflicting evidence on the interaction of these gasotransmitters, and their overall contribution to the microcirculation in newborns is not known. The aim of this study was to measure the levels of all 3 gasotransmitters, characterise their interrelationships and elucidate their combined effects on microvascular blood flow. Methods 90 preterm neonates were studied at 24h postnatal age. Microvascular studies were performed by laser Doppler. Arterial COHb levels (a measure of CO) were determined through co-oximetry. NO was measured as nitrate and nitrite in urine. H2S was measured as thiosulphate by liquid chromatography. Relationships between levels of the gasotransmitters and microvascular blood flow were assessed through partial correlation controlling for the influence of gestational age. Structural equation modelling was used to examine the combination of these effects on microvascular blood flow and derive a theoretical model of their interactions. Results No relationship was observed between NO and CO (p = 0.18, r = 0.18). A positive relationship between NO and H2S (p = 0.008, r = 0.28) and an inverse relationship between CO and H2S (p = 0.01, r = -0.33) exists. Structural equation modelling was used to examine the combination of these effects on microvascular blood flow. The model with the best fit is presented. Conclusions The relationships between NO and H2S, and CO and H2S may be of importance in the preterm newborn, particularly as NO levels in males are associated with higher H2S levels and higher microvascular blood flow and CO in females appears to convey protection against vascular dysregulation. Here we present a theoretical model of these interactions and their overall effects on microvascular flow in the preterm newborn, upon which future mechanistic studies may be based.The authors would like to acknowledge the parents of the neonates enrolled in the 2CANS study for their participation, the staff of the Kaleidoscope Neonatal Intensive Care Unit at the John Hunter Children’s Hospital, and Kimberly-Clark Australia for providing the diapers used in this stud

The potential impact of recent UK immigration policy announcements in Scotland

In this perspective paper, we summarise recent changes to immigration policy and analyse their potential impact on Scotland. We highlight the contributions of immigrants to the Scottish economy and demographics, and discuss the effects the new immigration policies may have on sectors such as health and social care and higher education. We also call for more transparent government research on and consideration of the regional impacts of immigration policy

Feasibility of a self-completed history questionnaire in women requesting repeat combined hormonal contraception.

OBJECTIVE: To measure agreement between the client's and the clinician's responses to questions regarding client history as answered on a questionnaire based on the UK Medical Eligibility Criteria for Contraceptive Use (UKMEC) for combined hormonal contraception (CHC). METHODS: Clients aged 18 years and over, attending a central London community contraceptive clinic requesting a repeat supply of CHC, completed a history questionnaire and an evaluation form. Clinicians then completed their copy of the same questionnaire during the consultation. Percentage agreement and the Kappa statistic were used to assess the level of client-clinician agreement. RESULTS: Data from 328 client-clinician pairs were analysed. Agreement was above 93% for all identified risk factors. There was complete agreement for thrombosis, diabetes, stroke, cancer and liver problems. Least agreement was noted in the recording of migraine and abnormal bleeding. For all risk factors except smoking, the proportion of clients reporting a risk factor was more than the proportion of clinicians reporting a risk factor. No clinically important information relevant to a particular client's use of CHC was missed and none of them would have been wrongly prescribed the CHC based just on their self-completed questionnaires. Most women (97%) were happy with this method of history taking. CONCLUSIONS: A self-completed history questionnaire is acceptable to women and can potentially replace traditional routine medical history taking for continuing CHC. Women completed the questionnaire with a high degree of reliability. There was complete client-clinician agreement on UKMEC Category 4 criteria. Overall, clients reported more risk factors than clinicians, which increases the safety of the questionnaire