Development of High Performance Concrete for Use on Tennessee Bridge Decks and Overlays

The purpose of this study was to develop a High Performance Concrete mix design to be used on bridge decks and overlays in Tennessee. A total of eight mix designs were tested in this study. Both gap-graded and dense-graded aggregate combinations were used in the study. Each mix was tested for fresh and hardened concrete properties. Fresh properties include slump, air content, unit weight, and temperature. Hardened properties include 7 and 28-day compressive strength, freeze-thaw durability, drying shrinkage, and chloride ion permeability. Although further research is recommended, one promising mix was found as a result of this study. Mix 2F1 (dense-graded with 25% fly ash replacement) was found to meet all performance characteristics and was chosen because it has possible economic savings

Teaching Faulkner

Teaching Faulkner I: The Bear / Robert W. Hamblin and James B. Carothers. Yerby AuditoriumTeaching Faulkner II: Faulkner\u27s Dirt / Charles A. Pee

Teaching Faulkner

Teaching Faulkner I / Robert W. Hamblin and Arlie Herron. Ole Miss Union 404 A&BTeaching Faulkner II / James B. Carothers and Charles A. Peek. Ole Miss Union 405 A&

Teaching Faulkner

Teaching Faulkner I / James B. Carothers and Robert W. Hamblin. Yerby AuditoriumTeaching Faulkner II / Arlie Herron and Charles A. Peek. Barnard Observator

Teaching Faulkner

Teaching Faulkner I: Faulkner\u27s Use of Landscape / Arlie E. Herron. Barnard ObservatoryTeaching Faulkner II: Open Topic / Robert W. Hamblin, James B. Carothers, and Charles A. Peek. Yerby Auditoriu

Teaching Faulkner

Teaching Faulkner I / James B. Carothers and Robert W. Hamblin. Yerby AuditoriumTeaching Faulkner II / Arlie E. Herron and Charles A. Peek. Barnard Observator

The Informal Logic of Mathematical Proof

Informal logic is a method of argument analysis which is complementary to that of formal logic, providing for the pragmatic treatment of features of argumentation which cannot be reduced to logical form. The central claim of this paper is that a more nuanced understanding of mathematical proof and discovery may be achieved by paying attention to the aspects of mathematical argumentation which can be captured by informal, rather than formal, logic. Two accounts of argumentation are considered: the pioneering work of Stephen Toulmin [The uses of argument, Cambridge University Press, 1958] and the more recent studies of Douglas Walton, [e.g. The new dialectic: Conversational contexts of argument, University of Toronto Press, 1998]. The focus of both of these approaches has largely been restricted to natural language argumentation. However, Walton's method in particular provides a fruitful analysis of mathematical proof. He offers a contextual account of argumentational strategies, distinguishing a variety of different types of dialogue in which arguments may occur. This analysis represents many different fallacious or otherwise illicit arguments as the deployment of strategies which are sometimes admissible in contexts in which they are inadmissible. I argue that mathematical proofs are deployed in a greater variety of types of dialogue than has commonly been assumed. I proceed to show that many of the important philosophical and pedagogical problems of mathematical proof arise from a failure to make explicit the type of dialogue in which the proof is introduced.Comment: 14 pages, 1 figure, 3 tables. Forthcoming in Perspectives on Mathematical Practices: Proceedings of the Brussels PMP2002 Conference (Logic, Epistemology and the Unity of the Sciences Series), J. P. Van Bendegem & B. Van Kerkhove, edd. (Dordrecht: Kluwer, 2004

Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope

The heavy chain IGHV1-69 germline gene exhibits a high level of polymorphism and shows biased use in protective antibody (Ab) responses to infections and vaccines. It is also highly expressed in several B cell malignancies and autoimmune diseases. G6 is an anti-idiotypic monoclonal Ab that selectively binds to IGHV1-69 heavy chain germline gene 51p1 alleles that have been implicated in these Ab responses and disease processes. Here, we determine the co-crystal structure of humanized G6 (hG6.3) in complex with anti-influenza hemagglutinin stem-directed broadly neutralizing Ab D80. The core of the hG6.3 idiotope is a continuous string of CDR-H2 residues starting with M53 and ending with N58. G6 binding studies demonstrate the remarkable breadth of binding to 51p1 IGHV1-69 Abs with diverse CDR-H3, light chain, and antigen binding specificities. These studies detail the broad expression of the G6 cross-reactive idiotype (CRI) that further define its potential role in precision medicine