Process map for technology commercialization at Missouri Innovation Center

This presentation provided Expo attendees with a road map for commercializing new technology

Nota preliminar sobre quebra de dormência em sementes de leguminosas arbóreas

Seeds of 33 leguminous tree species were tested for germination following mechanical or chemical scarification. The treatments gave germination of over 50% for 28 of the species. Mechanical or chemical scarification of about three times the number of seeds needed for an experiment with leguminous tree species is recommended as a rule of thumb when the germination rate of the seeds is in doubt.  A germinação das sementes de 33 leguminosas arbóreas foi testada após escarificação mecânica ou química. As sementes de 28 espécies, após escarificação, apresentaram mais de 50% de germinação. Quando não se conhece a taxa de germinação, como regra geral, recomenda-se fazer escarificação química ou mecânica de, aproximadamente, três vezes a quantidade de sementes de leguminosas arbóreas a serem usadas

Introduction: historical geographies of internationalism, 1900-1950

This introduction to a special issue on historical geographies of internationalism begins by situating the essays that follow in relation to the on-going refugee crisis in Europe and beyond. This crisis has revealed, once again, both the challenges and the potential of internationalism as a form political consciousness and the international as a scale of political action. Recent work has sought to re-conceptualise internationalism as the most urgent scale at which governance, political activity and resistance must operate when confronting the larger environmental, economic, and strategic challenges of the twenty-first century. Although geographers have only made a modest contribution to this work, we argue that they have a significant role to play. The essays in this special issue suggest several ways in which a geographical perspective can contribute to rethinking the international: by examining spaces and sites not previously considered in internationalist histories; by considering the relationship between internationalism in the abstract and the geographical and historical specifics of its creation; and by analysing the interlocking of internationalism with other political projects. We identify, towards the end of this essay, seven ways that internationalism might be reconsidered geographically in future research: through its spatialities and temporalities, the role of newly independent states, science and research, identity politics, and with reference to its performative and visual dimensions

Conferencing the international at the World Pacifist Meeting in India, 1949

This paper considers how the act of conferencing was central to imagining, negotiating and contesting post-war pacifism as an internationalist project. The paper contends that internationalism and the international conference are inexorably entwined. Through studying the conference geographers can explore the situated historical and political geographies of internationalism which belies its otherwise transcendent or universalist claims. A reading of the 1949 World Pacifist Meeting in India is used to make two key arguments. Firstly, it shows how conferences operate as stage-managed events through which to script and perform an alternative vision of internationalism. Half conference, half pilgrimage, the global composition of delegates was arranged to suggest a space ‘singularly free from any sense of geographical limitation’. Yet total immersion in the rich cultural and historical context of India marked an uneven internationalist arena, where the ‘Land of Gandhi’ was held with unparalleled revere. Secondly, whilst geographers and others have turned to conferencing in recent years, this has largely been contained to ‘summitry’ and high-end diplomacy. This paper calls for geographers to consider a wider range of conferencing spaces and practices, and argues that studying ‘other conferences’ by necessity opens up consideration of other forms of internationalism. The paper concludes that the World Pacifist Meeting’s delegates imagined an alternative form of internationalism, exemplified by an alternative form of international conference, which sought to challenge state-centric readings of global power relations

Next Generation Short-Term Forecasting of Wind Power – Overview of the ANEMOS Project.

International audienceThe aim of the European Project ANEMOS is to develop accurate and robust models that substantially outperform current state-of-the-art methods, for onshore and offshore wind power forecasting. Advanced statistical, physical and combined modelling approaches were developed for this purpose. Priority was given to methods for on-line uncertainty and prediction risk assessment. An integrated software platform, 'ANEMOS', was developed to host the various models. This system is installed by several end-users for on-line operation and evaluation at a local, regional and national scale. Finally, the project demonstrates the value of wind forecasts for the power system management and market integration of wind power. Keywords: Wind power, short-term forecasting, numerical weather predictions, on-line software, tools for wind integration

NAD deficiency, congenital malformations, and niacin supplementation

BACKGROUND: Congenital malformations can be manifested as combinations of phenotypes that co-occur more often than expected by chance. In many such cases, it has proved difficult to identify a genetic cause. We sought the genetic cause of cardiac, vertebral, and renal defects, among others, in unrelated patients. METHODS: We used genomic sequencing to identify potentially pathogenic gene variants in families in which a person had multiple congenital malformations. We tested the function of the variant by using assays of in vitro enzyme activity and by quantifying metabolites in patient plasma. We engineered mouse models with similar variants using the CRISPR (clustered regularly interspaced short palindromic repeats)–Cas9 system. RESULTS: Variants were identified in two genes that encode enzymes of the kynurenine pathway, 3-hydroxyanthranilic acid 3,4-dioxygenase (HAAO) and kynureninase (KYNU). Three patients carried homozygous variants predicting loss-of-function changes in the HAAO or KYNU proteins (HAAO p.D162*, HAAO p.W186*, or KYNU p.V57Efs*21). Another patient carried heterozygous KYNU variants (p.Y156* and p.F349Kfs*4). The mutant enzymes had greatly reduced activity in vitro. Nicotinamide adenine dinucleotide (NAD) is synthesized de novo from tryptophan through the kynurenine pathway. The patients had reduced levels of circulating NAD. Defects similar to those in the patients developed in the embryos of Haao-null or Kynu-null mice owing to NAD deficiency. In null mice, the prevention of NAD deficiency during gestation averted defects. CONCLUSIONS: Disruption of NAD synthesis caused a deficiency of NAD and congenital malformations in humans and mice. Niacin supplementation during gestation prevented the malformations in mice

From conception to corporation : getting off square one

The slides for the panelists' presentations can be found by going to Presentations collection for the Missouri Technology Expo 2010: https://mospace.umsystem.edu/xmlui/handle/10355/9623This panel discussed how to grow a business once founded. Concepts addressed include tax liability, commercialization pathways, client relationships and capitalization strategy