30 research outputs found
Reconciling the stratigraphy and depositional history of the Lycian orogen-top basins, SW Anatolia
Terrestrial fossil records from the SWAnatolian basins are crucial both for regional correlations and palaeoenvironmental reconstructions.
By reassessing biostratigraphic constraints and incorporating new fossil data, we calibrated and reconstructed the late Neogene
andQuaternary palaeoenvironments within a regional palaeogeographical framework. The culmination of the Taurides inSWAnatolia
was followed by a regional crustal extension from the late Tortonian onwards that created a broad array of NE-trending orogen-top
basins with synchronic associations of alluvial fan, fluvial and lacustrine deposits. The terrestrial basins are superimposed on the upper
Burdigalian marine units with a c. 7 myr of hiatus that corresponds to a shift from regional shortening to extension. The initial infill of
these basins is documented by a transition from marginal alluvial fans and axial fluvial systems into central shallow-perennial lakes
coinciding with a climatic shift from warm/humid to arid conditions. The basal alluvial fan deposits abound in fossil macro-mammals
of an early Turolian (MN11–12; late Tortonian) age. The Pliocene epoch in the region was punctuated by subhumid/humid conditions
resulting in a rise of local base levels and expansion of lakes as evidenced by marsh-swamp deposits containing diverse fossilmammal
assemblages indicating late Ruscinian (lateMN15; late Zanclean) ageWe are grateful for the support of the international
bilateral project between The Scientific and Technological Research
Council of Turkey (TUBITAK) and The Russian Scientific Foundation
(RFBR) with grant a number of 111Y192. M.C.A. is grateful to the
Turkish Academy of Sciences (TUBA) for a GEBIP (Young Scientist
Award) grant. T.K. and S.M. are grateful to the Ege University
Scientific Research Center for the TTM/002/2016 and TTM/001/2016
projects. M.C.A., H.A., S.M. and M.B. have obtained Martin and
Temmick Fellowships at Naturalis Biodiversity Center (Leiden). F.A.D.
is supported by a Mehmet Akif Ersoy University Scientific Research
Grant. T.A.N. is supported by an Alexander-von-Humboldt
Scholarship. L.H.O. received support from TUBITAK under the 2221
program for visiting scientists
Prediction of unfavorable outcomes in cryptococcal meningitis: results of the multicenter infectious Diseases International Research Initiative (ID-IRI) cryptococcal meningitis study (vol 37, pg 1231, 2018)
WOS: 000435950400005PubMed: 29855841In the original version of this article, Mustafa Sunbul was not included in the list of authors for this article. The name has been added accordingly
Evaluation of patients with Crimean-Congo hemorrhagic fever in Bolu, Turkey
Background: Crimean-Congo hemorrhagic fever (CCHF), which is associated
with a high mortality rate in the Black Sea region of Turkey, has
received increasing attention. Objective: In this study, the
epidemiological features, clinical and laboratory findings, treatments,
and outcomes of patients diagnosed with CCHF between 2006 and 2012
based on data obtained from the Bolu Provincial Directorate of Health
(BPDH) were evaluated. Methods: BPDH data were reviewed for the period
between 1 January 2006 and 31 July 2012. The locations where the tick
had attached to the patient, the site of the tick bite on the
patient’s body, the dates of tick bite and removal, and the
demographic characteristics of each patient were recorded. BPDH data on
the total number of tick bites, patients with confirmed CCHF, and
deaths due to CCHF in Bolu Province during the study period were also
evaluated. Results: A total of 46 patients with CCHF and 38 patients
without CCHF but who had been bitten by ticks were admitted to the
BPDH. Of the patients with CCHF, 54.3% were female. The mean age of the
patients was 46.88 ± 2.05 years (range,1–79 years). The
mortality rate was 8.82%. Patients were predominantly observed in June
and July. When the patients were distributed according to their
occupations, the majority was houswife (48.6%), followed by animal
husbandry worker (27.0%), farmer (10.8%), health worker (5.4%), and
other (8.1%). The symptoms of the patients with CCHF included fatigue
(60.9%), fever (60.9%), and myalgia (60.9%). Of those patients with
CCHF, 41.3% were determined to have a high fever. Conclusions: The
probability of developing CCHF decreased as the duration of tick
attachment increased. Moreover, although the clinical presentation is
important, it is not diagnostic. Physical examination and laboratory
findings become more specific in later stages
The Büyük Menderes River: Origin of Meandering Phenomenon
The Büyük Menderes River is the longest river that discharges into the Aegean Sea, with a length of 615 km. It is one of the main rivers dominating in the geomorphology of western Turkey, with its drainage basin that reaches to 24,000 km2. The river is also very important because of its meandering channel patterns. The term ‘meandering’ in geomorphology, architecture and art originates from the ancient name of this river: Maiandros. Its catchment area mainly consists of three courses located in the main grabens of the region. The upper course of the Büyük Menderes River is located in the Baklan-Dinar Graben, while the middle and lower courses are in the Denizli and Büyük Menderes grabens, respectively. The aim of this study is to describe the meandering channel features of this river in its current course from its source to its mouth, and related landforms and landscapes. © 2019, Springer Nature Switzerland AG
Correction to: Prediction of unfavorable outcomes in cryptococcal meningitis: results of the multicenter infectious Diseases International Research Initiative (ID-IRI) cryptococcal meningitis study.
In the original version of this article, Mustafa Sunbul was not included in the list of authors for this article. The name has been added accordingly
Prediction of unfavorable outcomes in cryptococcal meningitis: results of the multicenter Infectious Diseases International Research Initiative (ID-IRI) cryptococcal meningitis study.
Cryptococcal meningitis (CM) is mostly seen in immunocompromised patients, particularly human immunodeficiency virus (HIV)-positive patients, but CM may also occur in apparently immunocompetent individuals. Outcome analyses have been performed in such patients but, due to the high prevalence of HIV infection worldwide, CM patients today may be admitted to hospitals with unknown HIV status, particularly in underdeveloped countries. The objective of this multicenter study was to analyze all types of CM cases in an aggregate cohort to disclose unfavorable outcomes. We retrospectively reviewed the hospitalized CM patients from 2000 to 2015 in 26 medical centers from 11 countries. Demographics, clinical, microbiological, radiological, therapeutic data, and outcomes were included. Death, neurological sequelae, or relapse were unfavorable outcomes. Seventy (43.8%) out of 160 study cases were identified as unfavorable and 104 (65%) were HIV infected. On multivariate analysis, the higher Glasgow Coma Scale (GCS) scores (p = 0.021), cerebrospinal fluid (CSF) leukocyte counts > 20 (p = 0.038), and higher CSF glucose levels (p = 0.048) were associated with favorable outcomes. On the other hand, malignancy (p = 0.026) was associated with poor outcomes. Although all CM patients require prompt and rational fungal management, those with significant risks for poor outcomes need to be closely monitored