Transient Analysis of Primary Feed Pump Trip for 700 MWe IPHWR

700 MWe Indian Pressurized Heavy Water Reactor (IPHWR) is a horizontal channel type reactor with two loops of Primary Heat Transport (PHTS) system. Three (two operating and one stand by) main boiler feed water pumps (BFP) supply feed water to Steam Generators (SGs). In the event of one of the running BFP trip, standby comes on line on auto. Transient analysis for this event is performed using in- house computer code ATMIKA.T .The transient has been initiated by tripping one of the pumps. Two cases are postulated: 1: BFP Trip and Standby BFP available on auto 2: BFP Trip and Standby pump not available. This paper provides timelines of following sequence of events which is important for operator’s action to maneuver the event, and the main findings of the study are: Following the tripping of one BFP, feed flow reduces and SGs level start falling. As SGs level fall, feed control valves open up in level control mode and system resistance in feed water circuit reduces. If the standby pump comes on auto, the SGs level recovers with a slight dip in level. The feed flow increases and settles down to normal value. Subsequently all the parameters converge to steady state value. Reactor continues to operate at 100% FP. In the event of main BFP trip without the availability of standby BFP, feed flow rate drops. SGs pressure rise slightly due to reduction in sub cooled feed flow and SGs level start to decrease. Reactor setback starts as SG level goes below set back limit. SG level continues to fall and reactor trips on SG Level very very low trip setting

Immune Responses to Defined Plasmodium Falciparum Antigens and Disease Susceptibility in Two Subpopulations of Northern India

The aim of this study was to investigate the prevalence of naturally acquired immune response to malaria in individuals of different age groups belonging to areas of northern India, Loni PHC (LN) and Dhaulana PHC (SD) of district Ghaziabad. Plasmodium falciparum-infected erythrocyte lysate and six synthetic peptides from different stages of P. falciparum (CSP, MSP1, AMA1, RAP1, EBA175 and PfG27) were used to determine both humoral and cellular immune responses. Plasma of individual subject was also analyzed for IL-4, IL-10, IFN-γ and TNF-α level. We observed an age-wise increasing trend of immunity in these two populations. There was a significant association between the number of antibody responders and recognition of stage-specific epitopes by antibodies. Peripheral blood mononuclear cells of more than 75% of individuals proliferated in response to stimulation by all the antigens in LN area. IL-4 and IL-10 responses were significantly higher in individuals of LN Area; whereas IFN-g and   TNF-a responses were higher in individuals of SD Area. It was also noticed that the frequency of responders to stage-specific antigens was higher in individuals from the LN area where the frequency of malaria was lower. The naturally acquired immune responses to P. falciparum antigens reflected the reduced risk of malaria in the study groups. The results demonstrated immunogenicity of the epitopes to P. falciparum in population of this endemic zone

A Decline in the X-ray through Radio Emission from GW170817 Continues to Support an Off-Axis Structured Jet

We present new observations of the binary neutron star merger GW170817 at $\Delta t\approx 220-290$ days post-merger, at radio (Karl G. Jansky Very Large Array; VLA), X-ray (Chandra X-ray Observatory) and optical (Hubble Space Telescope; HST) wavelengths. These observations provide the first evidence for a turnover in the X-ray light curve, mirroring a decline in the radio emission at $\gtrsim5\sigma$ significance. The radio-to-X-ray spectral energy distribution exhibits no evolution into the declining phase. Our full multi-wavelength dataset is consistent with the predicted behavior of our previously published models of a successful structured jet expanding into a low-density circumbinary medium, but pure cocoon models with a choked jet cannot be ruled out. If future observations continue to track our predictions, we expect that the radio and X-ray emission will remain detectable until $\sim 1000$ days post-merger.Comment: Accepted to ApJL. Updated version includes new VLA observations extending through 2018 June

The Binary Neutron Star event LIGO/VIRGO GW170817 a hundred and sixty days after merger: synchrotron emission across the electromagnetic spectrum

We report deep Chandra, HST and VLA observations of the binary neutron star event GW170817 at $t<160$ d after merger. These observations show that GW170817 has been steadily brightening with time and might have now reached its peak, and constrain the emission process as non-thermal synchrotron emission where the cooling frequency $\nu_c$ is above the X-ray band and the synchrotron frequency $\nu_m$ is below the radio band. The very simple power-law spectrum extending for eight orders of magnitude in frequency enables the most precise measurement of the index $p$ of the distribution of non-thermal relativistic electrons $N(\gamma)\propto \gamma^{-p}$ accelerated by a shock launched by a NS-NS merger to date. We find $p=2.17\pm0.01$, which indicates that radiation from ejecta with $\Gamma\sim3-10$ dominates the observed emission. While constraining the nature of the emission process, these observations do \emph{not} constrain the nature of the relativistic ejecta. We employ simulations of explosive outflows launched in NS ejecta clouds to show that the spectral and temporal evolution of the non-thermal emission from GW170817 is consistent with both emission from radially stratified quasi-spherical ejecta traveling at mildly relativistic speeds, \emph{and} emission from off-axis collimated ejecta characterized by a narrow cone of ultra-relativistic material with slower wings extending to larger angles. In the latter scenario, GW170817 harbored a normal SGRB directed away from our line of sight. Observations at $t\le 200$ days are unlikely to settle the debate as in both scenarios the observed emission is effectively dominated by radiation from mildly relativistic material.Comment: Updated with the latest VLA and Chandra dat

Neutral and Cationic Rare Earth Metal Alkyl and Benzyl Compounds with the 1,4,6-Trimethyl-6-pyrrolidin-1-yl-1,4-diazepane Ligand and Their Performance in the Catalytic Hydroamination/Cyclization of Aminoalkenes

A new neutral tridentate 1,4,6-trimethyl-6-pyrrolidin-1-yl-1,4-diazepane (L) was prepared. Reacting L with trialkyls M(CH2SiMe3)3(THF)2 (M = Sc, Y) and tribenzyls M(CH2Ph)3(THF)3 (M = Sc, La) yielded trialkyl complexes (L)M(CH2SiMe3)3 (M = Sc, 1; M = Y, 2) and tribenzyl complexes (L)M(CH2Ph)3 (M = Sc, 3; M = La, 4). Complexes 1 and 2 can be converted to their corresponding ionic compounds [(L)M(CH2SiMe3)2(THF)][B(C6H5)4] (M = Sc, Y) by reaction with [PhNMe2H][B(C6H5)4] in THF. Complexes 3 and 4 can be converted to cationic species [(L)M(CH2Ph)2]+ by reaction with [PhNMe2H][B(C6F5)4] in C6D5Br in the absence of THF. The neutral complexes 1-4 and their cationic derivatives were studied as catalysts for the hydroamination/cyclization of 2,2-diphenylpent-4-en-1-amine and N-methylpent-4-en-1-amine reference substrates and compared with ligand-free Sc, Y, and La neutral and cationic catalysts. The most effective catalysts in the series were the cationic L-yttrium catalyst (for 2,2-diphenylpent-4-en-1-amine) and the cationic lanthanum systems (for N-methylpent-4-en-1-amine). For the La catalysts, evidence was obtained for release of L from the metal during catalysis.

Sucrose helps regulate cold acclimation of Arabidopsis thaliana

A test was carried out to see if sucrose could regulate cold-acclimation-associated gene expression in Arabidopsis. In plants and excised leaves, sucrose caused an increase in GUS activity, as a reporter for the activity of the cold-responsive COR78 promoter. This increase was transient at 21 °C but lasted for at least 4 d at 4 °C in continuous darkness. However, at 4 °C with a 16 h photoperiod, GUS activity was similarly high with solutions lacking sucrose or with different concentrations of sucrose. In peeled lower epidermis in the cold dark environment, 40 mM sucrose increased COR78 transcript abundance to substantially above that in the controls, but sorbitol had no effect. Similarly to the cold and dark conditions, sucrose increased COR78 transcript abundance in the epidermis in the warm light and warm dark environments, but not in a cold light environment. Sucrose had much less effect on COR78 transcript abundance in leaves without the lower epidermis. Thus sucrose regulates expression of COR78, possibly mainly in the epidermis, at the level of transcription. Furthermore, 40 mM sucrose at 4 °C for 24 h in constant darkness was sufficient to give the same GUS activity as in fully acclimated plants of the same age in a 16 h photoperiod, although by 48 h, GUS activity had become intermediate between control and fully cold-acclimated plants. Thus sucrose has a regulatory role in the acclimation of whole plants to cold and this may be important during diurnal dark periods

Multi-Messenger Astronomy with Extremely Large Telescopes

The field of time-domain astrophysics has entered the era of Multi-messenger Astronomy (MMA). One key science goal for the next decade (and beyond) will be to characterize gravitational wave (GW) and neutrino sources using the next generation of Extremely Large Telescopes (ELTs). These studies will have a broad impact across astrophysics, informing our knowledge of the production and enrichment history of the heaviest chemical elements, constrain the dense matter equation of state, provide independent constraints on cosmology, increase our understanding of particle acceleration in shocks and jets, and study the lives of black holes in the universe. Future GW detectors will greatly improve their sensitivity during the coming decade, as will near-infrared telescopes capable of independently finding kilonovae from neutron star mergers. However, the electromagnetic counterparts to high-frequency (LIGO/Virgo band) GW sources will be distant and faint and thus demand ELT capabilities for characterization. ELTs will be important and necessary contributors to an advanced and complete multi-messenger network.Comment: White paper submitted to the Astro2020 Decadal Surve

The emergence of a new source of X-rays from the binary neutron star merger GW170817

The binary neutron-star (BNS) merger GW170817 is the first celestial object from which both gravitational waves (GWs) and light have been detected enabling critical insight on the pre-merger (GWs) and post-merger (light) physical properties of these phenomena. For the first $\sim 3$ years after the merger the detected radio and X-ray radiation has been dominated by emission from a structured relativistic jet initially pointing $\sim 15-25$ degrees away from our line of sight and propagating into a low-density medium. Here we report on observational evidence for the emergence of a new X-ray emission component at $\delta t>900$ days after the merger. The new component has luminosity $L_x \approx 5\times 10^{38}\rm{erg s^{-1}}$ at 1234 days, and represents a $\sim 3.5\sigma$ - $4.3\sigma$ excess compared to the expectations from the off-axis jet model that best fits the multi-wavelength afterglow of GW170817 at earlier times. A lack of detectable radio emission at 3 GHz around the same time suggests a harder broadband spectrum than the jet afterglow. These properties are consistent with synchrotron emission from a mildly relativistic shock generated by the expanding merger ejecta, i.e. a kilonova afterglow. In this context our simulations show that the X-ray excess supports the presence of a high-velocity tail in the merger ejecta, and argues against the prompt collapse of the merger remnant into a black hole. However, radiation from accretion processes on the compact-object remnant represents a viable alternative to the kilonova afterglow. Neither a kilonova afterglow nor accretion-powered emission have been observed before.Comment: 66 pages, 12 figures, Submitte