Morganella morganii in sinonasal region: A rare case report

Morganella morganii is a gram negative pathogen andmay cause potentially lethal disease especially in patientswith underlying or immunosuppressive disease. It is commonlyfound in long-term urinary catheter used and immunesystem deficiency patients as nosocomial disease.Involving other systems such as skin, skeletal systemand central nervous system can be seen too. Sporadicoccurrence is rare and can be seen in any system by variouscauses like AIDS, snake bites and poisoning. In thiscase we present sporadic Morganella morganii infectionon sinonasal region with the presence of sinusitis, sinocutaneousfistula, preseptal cellulitis and hard palate defecton 58 year old male diabetic patient. Microbiologicalassessment from open wound and sinuses were reportedas Morganella morganii. To our knowledge, this is the firstcase of sino-nasal Morganella morganii infection with sino-cutaneous fistula, preseptal cellulitis and maxillofacialbone destruction. J Clin Exp Invest 2013; 4 (3): 383-386Key words: Morganella Morganii, sino-nasal fistula, preseptalcellulitis, bone destructio

Auricular cartilage repair using cryogel scaffolds loaded with BMP-7-expressing primary chondrocytes

The loss of cartilage tissue due to trauma, tumour surgery or congenital defects, such as microtia and anotia, is one of the major concerns in head and neck surgery. Recently tissue-engineering approaches, including gene delivery, have been proposed for the regeneration of cartilage tissue. In this study, primary chondrocytes were genetically modified with plasmid-encoding bone morphogenetic protein-7 (BMP-7) via the commercially available non-viral Turbofect vector, with the aim of bringing ex vivo transfected chondrocytes to resynthesize BMP-7 in vitro as they would in vivo. Genetically modified cells were implanted into gelatin–oxidized dextran scaffolds and cartilage tissue formation was investigated in 15 × 15 mm auricular cartilage defects in vivo in 48 New Zealand (NZ) white rabbits for 4 months. The results were evaluated via histology and early gene expression. Early gene expression results indicated a strong effect of exogenous BMP-7 on matrix synthesis and chondrocyte growth. In addition, histological analysis results exhibited significantly better cartilage healing with BMP-7-modified (transfected) cells than in the non-modified (non-transfected) group and as well as the control

Septoplasty: Under general or sedation anesthesia. Which is more efficacious?

WOS: 000339973800014PubMed ID: 24384631The objective of the study was to assess the more efficacious anesthesia method in septal surgery. The prospective study was conducted at an academic secondary referral center. A prospective chart review of 60 patients, between the ages of 16 and 65, who underwent septal surgery under general (GA) or sedation (SDA) anesthesia during 1-year period was done. Mean age of the patients was 44.30 +/- A 13.29. Patients were divided into two groups according to the anesthesia method: general (group 1) or sedation (group 2). Intraoperative hemodynamic variables, surgery time, intraoperative blood loss volume, length of hospital stay, postoperative vomiting and nausea, postoperative pain score according to the visual analog scale (VAS) and cost analysis of each method were compared. Thirty-six males and 24 females with a mean age 44.30 +/- A 13.29 were included to the study. Total operation time, operation time, intraoperative and postoperative bleeding volume, postoperative nausea and vomiting, duration of hospital stay after surgery, were better in group 2. Postoperative pain scores and patient satisfaction about surgery were not statistically different. Cost of anesthesia in group 1 per patient was $44.35 +/- A 10.81 and in group 2,$16.29 +/- A 11.88 (p < 0.01). Hospital stay after surgery was much longer in group 1 than group 2 (p < 0.01). Using SDA is better in many ways including cost-effectiveness than using GA for septoplasty operation

Ganglioneuroma of the neck: A case report

Objectives: An unusual left parapharyngeal ganglioneuroma case was discussed in the context of diagnostic difficulties, surgical tricks and Horner syndrome as a main surgical complication.Methods: The patient presented with a painless neck mass. Fine needle aspiration did not give any clue regarding diagnosis. The mass was removed totally by a challenging surgery.&nbsp;Results: Histopathology revealed ganglioneuroma. Horner syndrome occurred after surgery.Conclusion: Due to the scarcity of ganglioneuromas and the lack of specific signs and symptoms, it is often difficult to reach a definitive diagnosis prior to pathological examination. Ganglioneuromas should be considered in differential diagnosis of cervical neck masses located medial to main neurovascular structures. The patients should be warned of the possible complication of Horner syndrome.</p

Perception of male otolaryngologists on gender discrimination: a comparative study

Purpose: To gather information on perception of male otolaryngologists (MORLs) about gender discrimination towards female otolaryngologists (FORLs). Methods: MORLs were invited to participate to an online survey. Minimum participation requirement was completion of at least their first year of residency. The responses were analyzed and compared vis-a-vis with the previously conducted similar survey among FORLs. Results: Statistically significant responses on the Likert scale are classified in four main groups. MORLs and FORLs share the same views about financial factors, benefits and opportunities, housework as burden, establishing work–life balance and physical strength requirements. They have opposing views about FORLs being meticulous, exposed to more negative attitude of the opposite gender and men’s dominance in decision-making. FORLs don’t have consensus, but MORLs disagree about MORLs being favored in pursuing academic careers. On the other hand, MORLs don’t have consensus, but FORLs agree about patients having more confidence in MORLs. Conclusion: MORLs don’t usually have any confrontation with FORLs in regards to the roles of women in the society such as their motherhood role. On the other hand, MORLs show rather a contradiction on their perception towards the gender discrimination mainly in achieving career goals by FORLs such as growing in the profession and holding managing roles. When the views of the both gender group are compared, MORLs don’t seem to fully acknowledge FORLs’ gender discrimination experience. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature

Kafa travması sonrası karşı kulakta sensörinöral işitme kaybı

Sensorineural hearing loss following the head traumais one of the most common complications that mightoccur. Although radiological evidence that presents thelabyrinth damage as sensorineural hearing loss in somepatients complaining of these symptoms after thetrauma; cannot be determined. The underlyingmechanism is commonly assumed to be the concussionof the labyrinth that is frequently seen in headtraumas. In this paper, we would like to presentdouble‐sided tinnitus and hearing loss that developedafter the head trauma due to the concussion of thelabyrinth in the opposite ear without temporal bonefractures.Kafa travması sonrası işitme kaybı sık karşılaşılan komplikasyonlardan biridir.Travma sonrasında bu şikayetlerle gelen bazı hastalarda sensörinöral işitme kaybı için labirent hasarını gösteren radyolojik bir bulgu saptanamamakla beraber altta yatan mekanizmanın kafa travmalarında sıklıkla rastlanan labirentin konküzyonu olduğu varsayılmaktadır.Bu yazıda kafa travması sonrası temporal kemik fraktürü olmadan karşı kulakta labirentin konküzyon nedeniyle işitme kaybı ve çift taraflı tinnitus gelişmiş bir olguyu sunduk

Flexible CO2 laser treatment for subglottic stenosis

WOS: 000402750600071PubMed ID: 28277485Objectives: To assess the efficacy and safety of flexible fiber CO2 laser surgery for subglottic stenosis and to present retrospective experience of 14 patients treated with flexible fiber CO2 laser system. To determine the characteristics, management protocols, prognostic factors, and postoperative outcomes of the sample. Methods: Retrospective review of patients with subglottic stenosis undergoing flexible fiber CO2 laser surgery at the tertiary medical center. All demographic and clinical data were collected, radiologic and endoscopic evaluations were performed to assess the characteristics of stenosis. Myer-Cotton grading scale was used for classification of stenotic area. Results: All patients have subglottic stenosis due to intubation-related causes and inappropriate tracheostomy procedure. The duration of intubation period ranged from 15 days to 4 years; 11 patients have grade III stenosis according to Myer-Cotton system and there was cricoid involvement in 2 patients. The mean follow-up period was 5.2 months and postoperative decannulation was achieved in 10 patients (71.4%). Conclusions: Subglottic stenosis is the difficult situation to manage minimal invasively. Flexible fiber CO2 laser surgery is safe and effective in the management of properly selected patients and can be used as a first option for patients