A Statistical Description of AGN Jet Evolution from the VLBA Imaging and Polarimetry Survey (VIPS)

A detailed analysis of the evolution of the properties of core-jet systems within the VLBA Imaging and Polarimetry Survey (VIPS) is presented. We find a power-law relationship between jet intensity and width that suggests for the typical jet, little if any energy is lost as it moves away from its core. Using VLA images at 1.5 GHz, we have found evidence that parsec-scale jets tend to be aligned with the the direction of emission on kiloparsec scales. We also found that this alignment improves as the jets move farther from their cores on projected scales as small as ~50-100 pc. This suggests that realignment of jets on these projected scales is relatively common. We typically find a modest amount of bending (a change in jet position angle of ~5 deg.) on these scales, suggesting that this realignment may typically occur relatively gradually.Comment: Accepted to ApJ, 20 pages, 8 figure

Nonverbal Behavior During Face-to-face Social Interaction in Schizophrenia

Patients with a diagnosis of schizophrenia display social cognitive deficits. However, little is known about patients’ nonverbal communication during their social encounters with others. This review identified 17 studies investigating nonverbal communication in patients’ unscripted face-to-face interactions, addressing a) nonverbal differences between patients and others, b) nonverbal behavior of the patients’ partners, c) the association between nonverbal behavior and symptoms, and d) the association between nonverbal behavior and social outcomes. Patients displayed fewer nonverbal behaviors inviting interaction, with negative symptoms exacerbating this pattern. Positive symptoms were associated with heightened nonverbal behavior. Patients’ partners changed their own nonverbal behavior in response to the patient. Reduced prosocial behaviors, inviting interaction, were associated with poorer social outcomes. The evidence suggests that patients’ nonverbal behavior, during face-to-face interaction, is influenced by patients symptoms and impacts the success of their social interactions

Characteristics of Gamma-Ray Loud Blazars in the VLBA Imaging and Polarimetry Survey

The radio properties of blazars detected by the Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope have been observed as part of the VLBA Imaging and Polarimetry Survey (VIPS). This large, flux-limited sample of active galactic nuclei (AGN) provides insights into the mechanism that produces strong gamma-ray emission. At lower flux levels, radio flux density does not directly correlate with gamma-ray flux. We find that the LAT-detected BL Lacs tend to be similar to the non-LAT BL Lacs, but that the LAT-detected FSRQs are often significantly different from the non-LAT FSRQs. The differences between the gamma-ray loud and quiet FSRQs can be explained by Doppler boosting; these objects appear to require larger Doppler factors than those of the BL Lacs. It is possible that the gamma-ray loud FSRQs are fundamentally different from the gamma-ray quiet FSRQs. Strong polarization at the base of the jet appears to be a signature for gamma-ray loud AGN.Comment: 32 pages, 9 figures, accepted by Ap

The Impact of Shape on the Perception of Euler Diagrams

Euler diagrams are often used for visualizing data collected into sets. However, there is a significant lack of guidance regarding graphical choices for Euler diagram layout. To address this deficiency, this paper asks the question `does the shape of a closed curve affect a user's comprehension of an Euler diagram?' By empirical study, we establish that curve shape does indeed impact on understandability. Our analysis of performance data indicates that circles perform best, followed by squares, with ellipses and rectangles jointly performing worst. We conclude that, where possible, circles should be used to draw effective Euler diagrams. Further, the ability to discriminate curves from zones and the symmetry of the curve shapes is argued to be important. We utilize perceptual theory to explain these results. As a consequence of this research, improved diagram layout decisions can be made for Euler diagrams whether they are manually or automatically drawn

J16021+3326: New Multi-Frequency Observations of a Complex Source

We present multifrequency Very Long Baseline Array (VLBA) observations of J16021+3326. These observations, along with variability data obtained from the Owens Valley Radio Observatory (OVRO) candidate gamma-ray blazar monitoring program, clearly indicate this source is a blazar. The peculiar characteristic of this blazar, which daunted previous classification attempts, is that we appear to be observing down a precessing jet, the mean orientation of which is aligned with us almost exactly.Comment: 16 pages, 7 Figures, 2 Tables, accepted to Ap

Place matters: but does local leadership?

The arrival of New Labour into Government witnessed the prominent re-emergence of place onto the policy agenda. This heralded a range of area-based-initiatives designed to both tackle neighbourhood forms of deprivation and to re-establish a sense of identity and connection between individuals and their local community. In terms of place-making, effective and inclusive participation, representation and leadership were all identified as prerequisites for the creation of sustainable communities . But how important is local leadership and strategic vision within local public service organisations in achieving the desired place-making outcomes? This paper examines the extent to which local leadership and strategic vision represents a significant factor in promoting higher levels of satisfaction, belonging, cohesion and participation across single tier councils in England. The ensuing empirical evidence raises significant questions not only about the importance of local leadership in place-making, but also the environmental and organizational factors that shape local places

Detection of new point-sources in WMAP Cosmic Microwave Background (CMB) maps at high Galactic latitude. A new technique to extract point sources from CMB maps

In experimental microwave maps, point-sources can strongly affect the estimation of the power-spectrum and/or the test of Gaussianity of the Cosmic Microwave Background (CMB) component. As a consequence, their removal from the sky maps represents a critical step in the analysis of the CMB data. Before removing a source, however, it is necessary to detect it and source extraction consists of a delicate preliminary operation. In the literature, various techniques have been presented to detect point-sources in the sky maps. The most sophisticated ones exploit the multi-frequency nature of the observations that is typical of the CMB experiments. These techniques have "optimal" theoretical properties and, at least in principle, are capable of remarkable performances. Actually, they are rather difficult to use and this deteriorates the quality of the obtainable results. In this paper, we present a new technique, the "weighted matched filter" (WMF), that is quite simple to use and hence more robust in practical applications. Such technique shows particular efficiency in the detection of sources whose spectra have a slope different from zero. We apply this method to three Southern Hemisphere sky regions - each with an area of 400 square degrees - of the seven years Wilkinson Microwave Anisotropy Probe (WMAP) maps and compare the resulting sources with those of the two seven-year WMAP point-sources catalogues. In these selected regions we find seven additional sources not previously listed in WMAP catalogues and discuss their most likely identification and spectral properties.Comment: Astronomy and Astrophysics, 2011, in pres

The role of upstream sequences in selecting the reading frame on tmRNA

<p>Abstract</p> <p>Background</p> <p>tmRNA acts first as a tRNA and then as an mRNA to rescue stalled ribosomes in eubacteria. Two unanswered questions about tmRNA function remain: how does tmRNA, lacking an anticodon, bypass the decoding machinery and enter the ribosome? Secondly, how does the ribosome choose the proper codon to resume translation on tmRNA? According to the -1 triplet hypothesis, the answer to both questions lies in the unique properties of the three nucleotides upstream of the first tmRNA codon. These nucleotides assume an A-form conformation that mimics the codon-anticodon interaction, leading to recognition by the decoding center and choice of the reading frame. The -1 triplet hypothesis is important because it is the most credible model in which direct binding and recognition by the ribosome sets the reading frame on tmRNA.</p> <p>Results</p> <p>Conformational analysis predicts that 18 triplets cannot form the correct structure to function as the -1 triplet of tmRNA. We tested the tmRNA activity of all possible -1 triplet mutants using a genetic assay in <it>Escherichia coli</it>. While many mutants displayed reduced activity, our findings do not match the predictions of this model. Additional mutagenesis identified sequences further upstream that are required for tmRNA function. An immunoblot assay for translation of the tmRNA tag revealed that certain mutations in U85, A86, and the -1 triplet sequence result in improper selection of the first codon and translation in the wrong frame (-1 or +1) <it>in vivo</it>.</p> <p>Conclusion</p> <p>Our findings disprove the -1 triplet hypothesis. The -1 triplet is not required for accommodation of tmRNA into the ribosome, although it plays a minor role in frame selection. Our results strongly disfavor direct ribosomal recognition of the upstream sequence, instead supporting a model in which the binding of a separate ligand to A86 is primarily responsible for frame selection.</p

Shared understanding in psychiatrist–patient communication: Association with treatment adherence in schizophrenia

Objective Effective doctor–patient communication, including a shared understanding, is associated with treatment adherence across medicine. However, communication is affected by a diagnosis of schizophrenia and reaching a shared understanding can be challenging. During conversation, people detect and deal with possible misunderstanding using a conversational process called repair. This study tested the hypothesis that more frequent repair in psychiatrist–patient communication is associated with better treatment adherence in schizophrenia. Methods Routine psychiatric consultations involving patients with (DSM-IV) schizophrenia or schizoaffective disorder were audio-visually recorded. Consultations were coded for repair and patients’ symptoms and insight assessed. Adherence was assessed six months later. A principal components analysis reduced the repair data for further analysis. Random effects models examined the association between repair and adherence, adjusting for symptoms, consultation length and the amount patients spoke. Results 138 consultations were recorded, 118 were followed up. Patients requesting clarification of the psychiatrist's talk and the clarification provided by the psychiatrist was associated with adherence six months later (OR 5.82, 95% CI 1.31–25.82, p = 0.02). Conclusion The quality of doctor–patient communication also appears to influence adherence in schizophrenia. Practice implications Future research should investigate how patient clarification can be encouraged among patients and facilitated by psychiatrists’ communication