591 research outputs found

    Atomic position localization via dual measurement

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    We study localization of atomic position when a three-level atom interacts with a quantized standing-wave field in the Ramsey interferometer setup. Both the field quadrature amplitude and the atomic internal state are measured to obtain the atomic position information. It is found that this dual measurement scheme produces an interference pattern superimposed on a diffraction-like pattern in the atomic position distribution, where the former pattern originates from the state-selective measurement and the latter from the field measurement. The present scheme results in a better resolution in the position localization than the field-alone measurement schemes. We also discuss the measurement-correlated mechanical action of the standing-wave field on the atom in the light of Popper's test.Comment: 6.5 pages and 5 figure

    Functional SYNTAX Score for Risk Assessment in Multivessel Coronary Artery Disease

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    ObjectivesThis study was aimed at investigating whether a fractional flow reserve (FFR)-guided SYNTAX score (SS), termed “functional SYNTAX score” (FSS), would predict clinical outcome better than the classic SS in patients with multivessel coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI).BackgroundThe SS is a purely anatomic score based on the coronary angiogram and predicts outcome after PCI in patients with multivessel CAD. FFR-guided PCI improves outcomes by adding functional information to the anatomic information obtained from the angiogram.MethodsThe SS was prospectively collected in 497 patients enrolled in the FAME (Fractional Flow Reserve versus Angiography for Multivessel Evaluation) study. FSS was determined by only counting ischemia-producing lesions (FFR ≤0.80). The ability of each score to predict major adverse cardiac events (MACE) at 1 year was compared.ResultsThe 497 patients were divided into tertiles of risk based on the SS. After determining the FSS for each patient, 32% moved to a lower-risk group as follows. MACE occurred in 9.0%, 11.3%, and 26.7% of patients in the low-, medium-, and high-FSS groups, respectively (p < 0.001). Only FSS and procedure time were independent predictors of 1-year MACE. FSS demonstrated a better predictive accuracy for MACE compared with SS (Harrell's C of FSS, 0.677 vs. SS, 0.630, p = 0.02; integrated discrimination improvement of 1.94%, p < 0.001).ConclusionsRecalculating SS by only incorporating ischemia-producing lesions as determined by FFR decreases the number of higher-risk patients and better discriminates risk for adverse events in patients with multivessel CAD undergoing PCI. (Fractional Flow Reserve versus Angiography for Multivessel Evaluation [FAME]; NCT00267774

    Penetration depth anisotropy in two-band superconductors

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    The anisotropy of the London penetration depth is evaluated for two-band superconductors with arbitrary inter- and intra-band scattering times. If one of the bands is clean and the other is dirty in the absence of inter-band scattering, the anisotropy is dominated by the Fermi surface of the clean band and is weakly temperature dependent. The inter-band scattering also suppress the temperature dependence of the anisotropy

    First-principles study of nucleation, growth, and interface structure of Fe/GaAs

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    We use density-functional theory to describe the initial stages of Fe film growth on GaAs(001), focusing on the interplay between chemistry and magnetism at the interface. Four features appear to be generic: (1) At submonolayer coverages, a strong chemical interaction between Fe and substrate atoms leads to substitutional adsorption and intermixing. (2) For films of several monolayers and more, atomically abrupt interfaces are energetically favored. (3) For Fe films over a range of thicknesses, both Ga- and As-adlayers dramatically reduce the formation energies of the films, suggesting a surfactant-like action. (4) During the first few monolayers of growth, Ga or As atoms are likely to be liberated from the interface and diffuse to the Fe film surface. Magnetism plays an important auxiliary role for these processes, even in the dilute limit of atomic adsorption. Most of the films exhibit ferromagnetic order even at half-monolayer coverage, while certain adlayer-capped films show a slight preference for antiferromagnetic order.Comment: 11 two-column pages, 12 figures, to appear in Phys. Rev.

    Reversible magnetization of MgB2 single crystals with a two-gap nature

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    We present reversible magnetization measurements on MgB2 single crystals in magnetic fields up to 2.5 T applied parallel to the crystal's c-axis. This magnetization is analyzed in terms of the Hao-Clem model, and various superconducting parameters, such as the critical fields [Hc(0) and Hc2(0)], the characteristic lengths [xi(0) and lambda(0)], and the Ginzburg-Landau parameter, kappa, are derived. The temperature dependence of the magnetic penetration depth, lambda(T), obtained from the Hao-Clem analysis could not be explained by theories assuming a single gap. Our data are well described by using a two-gap model.Comment: 20 pages, 1 table, 4 figures, will be published in Phys. Rev.

    Nonlinear electrodynamics and CMB polarization

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    Recently WMAP and BOOMERanG experiments have set stringent constraints on the polarization angle of photons propagating in an expanding universe: Δα=(2.4±1.9)\Delta \alpha = (-2.4 \pm 1.9)^\circ. The polarization of the Cosmic Microwave Background radiation (CMB) is reviewed in the context of nonlinear electrodynamics (NLED). We compute the polarization angle of photons propagating in a cosmological background with planar symmetry. For this purpose, we use the Pagels-Tomboulis (PT) Lagrangian density describing NLED, which has the form L(X/Λ4)δ1  XL\sim (X/\Lambda^4)^{\delta - 1}\; X , where X=1/4FαβFαβX=1/4 F_{\alpha\beta} F^{\alpha \beta}, and δ\delta the parameter featuring the non-Maxwellian character of the PT nonlinear description of the electromagnetic interaction. After looking at the polarization components in the plane orthogonal to the (xx)-direction of propagation of the CMB photons, the polarization angle is defined in terms of the eccentricity of the universe, a geometrical property whose evolution on cosmic time (from the last scattering surface to the present) is constrained by the strength of magnetic fields over extragalactic distances.Comment: 17 pages, 2 figures, minor changes, references adde

    First Observation of Coherent π0\pi^0 Production in Neutrino Nucleus Interactions with Eν<E_{\nu}< 2 GeV

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    The MiniBooNE experiment at Fermilab has amassed the largest sample to date of π0\pi^0s produced in neutral current (NC) neutrino-nucleus interactions at low energy. This paper reports a measurement of the momentum distribution of π0\pi^0s produced in mineral oil (CH2_2) and the first observation of coherent π0\pi^0 production below 2 GeV. In the forward direction, the yield of events observed above the expectation for resonant production is attributed primarily to coherent production off carbon, but may also include a small contribution from diffractive production on hydrogen. Integrated over the MiniBooNE neutrino flux, the sum of the NC coherent and diffractive modes is found to be (19.5 ±\pm1.1 (stat) ±\pm2.5 (sys))% of all exclusive NC π0\pi^0 production at MiniBooNE. These measurements are of immediate utility because they quantify an important background to MiniBooNE's search for νμνe\nu_{\mu} \to \nu_e oscillations.Comment: Submitted to Phys. Lett.

    Comparing benefits from many possible computed tomography lung cancer screening programs: Extrapolating from the National Lung Screening Trial using comparative modeling

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    Background: The National Lung Screening Trial (NLST) demonstrated that in current and former smokers aged 55 to 74 years, with at least 30 pack-years of cigarette smoking history and who had quit smoking no more than 15 years ago, 3 annual computed tomography (CT) screens reduced lung cancer-specific mortality by 20% relative to 3 annual chest X-ray screens. We compared the benefits achievable with 576 lung cancer screening programs that varied CT screen number and frequency, ages of screening, and eligibility based on smoking. Methods and Findings: We used five independent microsimulation models with lung cancer natural history parameters previously calibrated to the NLST to simulate life histories of the US cohort born in 1950 under all 576 programs. 'Efficient' (within model) programs prevented the greatest number of lung cancer deaths, compared to no screening, for a given number of CT screens. Among 120 'consensus efficient' (identified as efficient across models) programs, the average starting age was 55 years, the stopping age was 80 or 85 years, the average minimum pack-years was 27, and the maximum years since quitting was 20. Among consensus efficient programs, 11% to 40% of the cohort was screened, and 153 to 846 lung cancer deaths were averted per 100,000 people. In all models, annual screening based on age and smoking eligibility in NLST was not efficient; continuing screening to age 80 or 85 years was more efficient. Conclusions: Consensus results from five models identified a set of efficient screening programs that include annual CT lung cancer screening using criteria like NLST eligibility but extended to older ages. Guidelines for screening should also consider harms of screening and individual patient characteristics

    Machine Learning Framework to Identify Individuals at Risk of Rapid Progression of Coronary Atherosclerosis : From the PARADIGM Registry

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    Background Rapid coronary plaque progression (RPP) is associated with incident cardiovascular events. To date, no method exists for the identification of individuals at risk of RPP at a single point in time. This study integrated coronary computed tomography angiography-determined qualitative and quantitative plaque features within a machine learning (ML) framework to determine its performance for predicting RPP. Methods and Results Qualitative and quantitative coronary computed tomography angiography plaque characterization was performed in 1083 patients who underwent serial coronary computed tomography angiography from the PARADIGM (Progression of Atherosclerotic Plaque Determined by Computed Tomographic Angiography Imaging) registry. RPP was defined as an annual progression of percentage atheroma volume 651.0%. We employed the following ML models: model 1, clinical variables; model 2, model 1 plus qualitative plaque features; model 3, model 2 plus quantitative plaque features. ML models were compared with the atherosclerotic cardiovascular disease risk score, Duke coronary artery disease score, and a logistic regression statistical model. 224 patients (21%) were identified as RPP. Feature selection in ML identifies that quantitative computed tomography variables were higher-ranking features, followed by qualitative computed tomography variables and clinical/laboratory variables. ML model 3 exhibited the highest discriminatory performance to identify individuals who would experience RPP when compared with atherosclerotic cardiovascular disease risk score, the other ML models, and the statistical model (area under the receiver operating characteristic curve in ML model 3, 0.83 [95% CI 0.78-0.89], versus atherosclerotic cardiovascular disease risk score, 0.60 [0.52-0.67]; Duke coronary artery disease score, 0.74 [0.68-0.79]; ML model 1, 0.62 [0.55-0.69]; ML model 2, 0.73 [0.67-0.80]; all P&lt;0.001; statistical model, 0.81 [0.75-0.87], P=0.128). Conclusions Based on a ML framework, quantitative atherosclerosis characterization has been shown to be the most important feature when compared with clinical, laboratory, and qualitative measures in identifying patients at risk of RPP
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