Study of KIC 8561221 observed by Kepler: an early red giant showing depressed dipolar modes

The continuous high-precision photometric observations provided by the CoRoT and Kepler space missions have allowed us to better understand the structure and dynamics of red giants using asteroseismic techniques. A small fraction of these stars shows dipole modes with unexpectedly low amplitudes. The reduction in amplitude is more pronounced for stars with higher frequency of maximum power. In this work we want to characterize KIC 8561221 in order to confirm that it is currently the least evolved star among this peculiar subset and to discuss several hypotheses that could help explain the reduction of the dipole mode amplitudes. We used Kepler short- and long-cadence data combined with spectroscopic observations to infer the stellar structure and dynamics of KIC 8561221. We then discussed different scenarios that could contribute to the reduction of the dipole amplitudes such as a fast rotating interior or the effect of a magnetic field on the properties of the modes. We also performed a detailed study of the inertia and damping of the modes. We have been able to characterize 37 oscillations modes, in particular, a few dipole modes above nu_max that exhibit nearly normal amplitudes. We have inferred a surface rotation period of around 91 days and uncovered the existence of a variation in the surface magnetic activity during the last 4 years. As expected, the internal regions of the star probed by the l = 2 and 3 modes spin 4 to 8 times faster than the surface. With our grid of standard models we are able to properly fit the observed frequencies. Our model calculation of mode inertia and damping give no explanation for the depressed dipole modes. A fast rotating core is also ruled out as a possible explanation. Finally, we do not have any observational evidence of the presence of a strong deep magnetic field inside the star.Comment: Accepted in A&A. 17 pages, 16 figure

Comparative actions of progesterone, medroxyprogesterone acetate, drospirenone and nestorone on breast cancer cell migration and invasion

<p>Abstract</p> <p>Background</p> <p>Limited information is available on the effects of progestins on breast cancer progression and metastasis. Cell migration and invasion are central for these processes, and require dynamic cytoskeletal and cell membrane rearrangements for cell motility to be enacted.</p> <p>Methods</p> <p>We investigated the effects of progesterone (P), medroxyprogesterone acetate (MPA), drospirenone (DRSP) and nestorone (NES) alone or with 17β-estradiol (E2) on T47-D breast cancer cell migration and invasion and we linked some of these actions to the regulation of the actin-regulatory protein, moesin and to cytoskeletal remodeling.</p> <p>Results</p> <p>Breast cancer cell horizontal migration and invasion of three-dimensional matrices are enhanced by all the progestins, but differences are found in terms of potency, with MPA being the most effective and DRSP being the least. This is related to the differential ability of the progestins to activate the actin-binding protein moesin, leading to distinct effects on actin cytoskeleton remodeling and on the formation of cell membrane structures that mediate cell movement. E2 also induces actin remodeling through moesin activation. However, the addition of some progestins partially offsets the action of estradiol on cell migration and invasion of breast cancer cells.</p> <p>Conclusion</p> <p>These results imply that P, MPA, DRSP and NES alone or in combination with E2 enhance the ability of breast cancer cells to move in the surrounding environment. However, these progestins show different potencies and to some extent use distinct intracellular intermediates to drive moesin activation and actin remodeling. These findings support the concept that each progestin acts differently on breast cancer cells, which may have relevant clinical implications.</p

CoRoT Measures Solar-Like Oscillations and Granulation in Stars Hotter Than the Sun

Oscillations of the Sun have been used to understand its interior structure. The extension of similar studies to more distant stars has raised many difficulties despite the strong efforts of the international community over the past decades. The CoRoT (Convection Rotation and Planetary Transits) satellite, launched in December 2006, has now measured oscillations and the stellar granulation signature in three main sequence stars that are noticeably hotter than the sun. The oscillation amplitudes are about 1.5 times as large as those in the Sun; the stellar granulation is up to three times as high. The stellar amplitudes are about 25% below the theoretic values, providing a measurement of the nonadiabaticity of the process ruling the oscillations in the outer layers of the stars