915 research outputs found
An association between lifespan and variation in insulin-like growth factor I receptor in sheep
Longevity in livestock is a valuable trait. When productive animals live longer, fewer replacement animals need to be raised. However, selection for longevity is not commonly the focus of breeding programs as direct selection for long-lived breeding stock is virtually impossible until late in the reproductive life of the animal. Additionally the underlying genetic factors or genes associated with longevity are either not known,
or not well understood. In humans, there is evidence that IGF 1 receptor (IGF1R) is involved in longevity. Polymorphism in the IGF1R gene has been associated with longevity in a number of species. Recently, 3 alleles
of ovine IGF1R were identified, but no analysis of the effect of IGF1R variation on sheep longevity has been reported. In this study, associations between ovine IGF1R variation, longevity and fertility were investigated.
Polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) was used to type IGF1R variation in 1,716 New Zealand sheep belonging to 6 breeds and 36 flocks. Ovine IGF1R C was associated with age when adjusting for flock (present 5.5 ± 0.2 yr, absent
5.0 ± 0.1 yr, P = 0.02). A general linear mixed effects model suggested an association (P = 0.06) between age and genotype, when correcting for flock. Pairwise comparison (least significant difference) of specific
genotypes revealed the difference to be between AA (5.0± 0.1 yr) and AC (5.6 ± 0.2 yr, P = 0.02). A weak negative Pearson correlation between fertility and longevity traits was observed (r = -0.25, P < 0.01). The finding of an association between variation in IGF1R and lifespan in sheep may be useful in prolonging the lifespan of sheep
Large-Amplitude Ultraviolet Variations in the RR Lyrae Star ROTSE-I J143753.84+345924.8
The NASA Galaxy Evolution Explorer (GALEX) satellite has obtained
simultaneous near and far ultraviolet light curves of the ROTSE-I Catalog RR
Lyrae ab-type variable star J143753.84+345924.8. A series of 38 GALEX Deep
Imaging Survey observations well distributed in phase within the star's
0.56432d period shows an AB=4.9mag variation in the far UV (1350-1750A) band
and an AB=1.8mag variation in the near UV (1750-2750A) band, compared with only
a 0.8mag variation in the broad, unfiltered ROTSE-I (4500-10000A) band. These
GALEX UV observations are the first to reveal a large RR Lyrae amplitude
variation at wavelengths below 1800A. We compare the GALEX and ROTSE-I
observations to predictions made by recent Kurucz stellar atmosphere models. We
use published physical parameters for the comparable period (0.57433d),
well-observed RR Lyrae star WY Antliae to compute predicted FUV, NUV, and
ROTSE-I light curves for J143753.84+345924.8. The observed light curves agree
with the Kurucz predictions for [Fe/H]=-1.25 to within AB=0.2mag in the GALEX
NUV and ROTSE-I bands, and within 0.5mag in the FUV. At all metallicities
between solar and one hundredth solar, the Kurucz models predict 6-8mag of
variation at wavelengths between 1000-1700A. Other variable stars with similar
temperature variations, such as Cepheids, should also have large-amplitude FUV
light curves, observable during the ongoing GALEX imaging surveys.Comment: This paper will be published as part of the Galaxy Evolution Explorer
(GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of
papers will be available at http:/www.galex.caltech.edu/PUBLICATIONS after
November 22, 200
GALEX UV Spectroscopy and Deep Imaging of LIRGs in the ELAIS S1 field
The ELAIS S1 field was observed by GALEX in both its Wide Spectroscopic and
Deep Imaging Survey modes. This field was previously observed by the Infrared
Space Observatory and we made use of the catalogue of multi-wavelength data
published by the ELAIS consortium to select galaxies common to the two samples.
Among the 959 objects with GALEX spectroscopy, 88 are present in the ELAIS
catalog and 19 are galaxies with an optical spectroscopic redshift. The
distribution of redshifts covers the range . The selected galaxies
have bolometric IR luminosities (deduced from the flux using ISOCAM) which means that we cover a wide range of galaxies from
normal to Ultra Luminous IR Galaxies. The mean () UV luminosity (not
corrected for extinction) amounts to
L_\sun for the low-z () sample. The UV slope (assuming
) correlates with the GALEX FUV-NUV color if
the sample is restricted to galaxies below . Taking advantage of the
UV and IR data, we estimate the dust attenuation from the IR/UV ratio and
compare it to the UV slope . We find that it is not possible to uniquely
estimate the dust attenuation from for our sample of galaxies. These
galaxies are highly extinguished with a median value .
Once the dust correction applied, the UV- and IR-based SFRs correlate. For the
closest galaxy with the best quality spectrum, we see a feature consistent with
being produced by a bump near 220nm in the attenuation curve.Comment: This paper has been published as part of the GALEX ApJL Special Issue
(ApJ 619, L63
The GALEX-VVDS Measurement of the Evolution of the 1500A Luminosity Function
We present the first measurement of the galaxy luminosity function at 1500A
between 0.2<z<1.2 based on GALEX-VVDS observations (1000 spectroscopic
redshifts for galaxies with NUV<24.5) and at higher z using existing datasets.
Our main results are summarized as follows :
(i) luminosity evolution is observed with Delta(Mstar)=-2.0 mag between z=0
and z=1 and Delta(Mstar)=-1.0mag between z=1 and z=3. This confirms that the
star formation activity was significantly higher in the past.
(ii) the LF slopes vary between -1.2< alpha <-1.65, with a marginally
significant hint of increase at higher z.
(iii) we split the sample in three restframe (B-I) intervals providing an
approximate spectral type classification: Sb-Sd, Sd-Irr and unobscured
starbursts. We find that the bluest class evolves less strongly in luminosity
than the two other classes. On the other hand their number density increases
sharply with z (15% in the local universe to 55% at z=1) while that of the
reddest classes decreases.Comment: 4 pages, 4 figures. This paper will be published as part of the
Galaxy Evolution Explorer (GALEX) Astrophysical Journal Letters Special
Issue.Links to the full set of papers will be available at :
http://www.galex.caltech.edu/PUBLICATIONS/ after November 22, 200
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Predicting DNA methylation level across human tissues
Differences in methylation across tissues are critical to cell differentiation and are key to understanding the role of epigenetics in complex diseases. In this investigation, we found that locus-specific methylation differences between tissues are highly consistent across individuals. We developed a novel statistical model to predict locus-specific methylation in target tissue based on methylation in surrogate tissue. The method was evaluated in publicly available data and in two studies using the latest IlluminaBeadChips: a childhood asthma study with methylation measured in both peripheral blood leukocytes (PBL) and lymphoblastoid cell lines; and a study of postoperative atrial fibrillation with methylation in PBL, atrium and artery. We found that our method can greatly improve accuracy of cross-tissue prediction at CpG sites that are variable in the target tissue [R2 increases from 0.38 (original R2 between tissues) to 0.89 for PBL-to-artery prediction; from 0.39 to 0.95 for PBL-to-atrium; and from 0.81 to 0.98 for lymphoblastoid cell line-to-PBL based on cross-validation, and confirmed using cross-study prediction]. An extended model with multiple CpGs further improved performance. Our results suggest that large-scale epidemiology studies using easy-to-access surrogate tissues (e.g. blood) could be recalibrated to improve understanding of epigenetics in hard-to-access tissues (e.g. atrium) and might enable non-invasive disease screening using epigenetic profiles
GALEX UV Color-Magnitude Relations and Evidence for Recent Star Formation in Early-type Galaxies
We have used the GALEX UV photometric data to construct a first
near-ultraviolet (NUV) color-magnitude relation (CMR) for the galaxies
pre-classified as early-type by SDSS studies. The NUV CMR is a powerful tool
for tracking the recent star formation history in early-type galaxies, owing to
its high sensitivity to the presence of young stellar populations. Our NUV CMR
for UV-weak galaxies shows a well-defined slope and thus will be useful for
interpreting the restframe NUV data of distant galaxies and studying their star
formation history. Compared to optical CMRs, the NUV CMR shows a substantially
larger scatter, which we interpret as evidence of recent star formation
activities. Roughly 15% of the recent epoch (z < 0.13) bright (M[r] < -22)
early-type galaxies show a sign of recent (< 1Gyr) star formation at the 1-2%
level (lower limit) in mass compared to the total stellar mass. This implies
that low level residual star formation was common during the last few billion
years even in bright early-type galaxies.Comment: This paper will be published as part of the Galaxy Evolution Explorer
(GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of
papers will be available at http://www.galex.caltech.edu/PUBLICATIONS/ after
November 22, 200
Preparation, structural characterisation and antibacterial properties of Ga-doped sol-gel phosphate-based glass
A sol-gel preparation of Ga-doped phosphate-based glass with potential application in antimicrobial devices has been developed. Samples of composition (CaO)(0.30)(Na2O)(0.20-x) (Ga2O3) (x) (P2O5)(0.50) where x = 0 and 0.03 were prepared, and the structure and properties of the gallium-doped sample compared with those of the sample containing no gallium. Analysis of the P-31 MAS NMR data demonstrated that addition of gallium to the sol-gel reaction increases the connectivity of the phosphate network at the expense of hydroxyl groups. This premise is supported by the results of the elemental analysis, which showed that the gallium-free sample contains significantly more hydrogen and by FTIR spectroscopy, which revealed a higher concentration of -OH groups in that sample. Ga K-edge extended X-ray absorption fine structure and X-ray absorption near-edge structure data revealed that the gallium ions are coordinated by six oxygen atoms. In agreement with the X-ray absorption data, the high-energy XRD results also suggest that the Ga3+ ions are octahedrally coordinated with respect to oxygen. Antimicrobial studies demonstrated that the sample containing Ga3+ ions had significant activity against Staphylococcus aureus compared to the control
Star formation in the nearby universe: the ultraviolet and infrared points of view
This work presents the main ultraviolet (UV) and far-infrared (FIR)
properties of two samples of nearby galaxies selected from the GALEX (\AA, hereafter NUV) and IRAS (m) surveys respectively.
They are built in order to get detection at both wavelengths for most of the
galaxies. Star formation rate (SFR) estimators based on the UV and FIR
emissions are compared. Systematic differences are found between the SFR
estimators for individual galaxies based on the NUV fluxes corrected for dust
attenuation and on the total IR luminosity. A combined estimator based on NUV
and IR luminosities seems to be the best proxy over the whole range of values
of SFR. Although both samples present similar average values of the birthrate
parameter b, their star-formation-related properties are substantially
different: NUV-selected galaxies tend to show larger values of for lower
masses, SFRs and dust attenuations, supporting previous scenarios for the star
formation history (SFH). Conversely, about 20% of the FIR-selected galaxies
show high values of , SFR and NUV attenuation. These galaxies, most of them
being LIRGs and ULIRGs, break down the downsizing picture for the SFH, however
their relative contribution per unit volume is small in the local Universe.
Finally, the cosmic SFR density of the local Universe is estimated in a
consistent way from the NUV and IR luminosities.Comment: 43 pages, 13 figures, accepted for publication in Astrophysical
Journal Supplement Serie
A Multi-Inventory Ensemble Analysis of the Effects of Atmospheric Rivers on Precipitation and Streamflow in the Namgang-Dam Basin in Korea
Atmospheric rivers (ARs) are an important concern in regional water management; however, little is known about the AR impacts on hydrology in East Asia (EA). This study analyzes the characteristics of storms, precipitation (P), streamflow (Q), and runoff coefficient (R) in the Namgang-dam basin in Korea related to ARs for 2000â2013, as well as the sensitivity of the analysis results to AR detection methods, using observed P, Q, and three different AR inventories. The basin experiences 37.3 storms annually, of which 54% are AR storms that provide over 60% of the annual P and Q. The AR (non-AR) storms are dominant in storm frequency and the storm-total P and Q for JanuaryâJuly (AugustâDecember) with peaks in July (August). The monthly AR frequency varies closely with the seasonal variations in the EA monsoon and the North Pacific storm track which modulate the number of extratropical cyclones. The AR storms produce most of the extreme events; they also generate larger storm-mean P and Q than the non-AR storms for all months. The seasonal variations in R are related to the total (AR- and non-AR storms combined) P through the seasonal soil water variations, making the AR effects on R unclear. Considering 95% confidence intervals, the AR storms are distinguished well from the non-AR storms in storm frequency and the storm-total and storm-mean P and Q. The sensitivity to AR inventories is not critical in quantifying the AR-storm characteristics and their impacts on hydrologic variables except for R
The Ultraviolet Galaxy Luminosity Function from GALEX data: Color Dependent Evolution at Low Redshift
We present measurements of the FUV (1530A) and NUV (2310A) galaxy luminosity
functions (LF) at low redshift (z<0.2) from GALEX observations matched to the
2dF Galaxy Redshift Survey. We split our FUV and NUV samples into two UV-bj
color bins and two redshift bins. As observed at optical wavelengths, the local
LF of the bluest galaxies tend to have steeper faint end slopes and fainter
characteristic magnitudes M* than the reddest subsamples. We find evidence for
color dependent evolution at very low redshift in both bands, with bright blue
galaxies becoming dominant in the highest redshift bin. The evolution of the
total LF is consistent with an 0.3 magnitude brightening between z=0 and 0.13,
in agreement with the first analysis of deeper GALEX fields probing adjacent
and higher redshifts.Comment: This paper will be published as part of the Galaxy Evolution Explorer
(GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of
papers will be available at : http://www.galex.caltech.edu/PUBLICATIONS/
after November 22, 200
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