201 research outputs found
Unusual Charged Higgs Signals at LEP-2
We have made a detailed study of the signals produced at LEP-2 from charged
scalar bosons whose dominant decay channels are into four fermions. The event
rates as well as kinematics of the final states are discussed when such scalars
are either pair-produced or are generated through a tree-level interaction
involving a charged scalar, the W and the Z. The backgrounds in both cases are
discussed. We also suggest the possibility of reconstructing the mass of such a
scalar at LEP-2.Comment: 12 pages, LateX, 9 Postscript figures, uses eps
Simultaneous expression of regulatory genes associated with specific drought‐adaptive traits improves drought adaptation in peanut
Adaptation of crops to drought-prone rain-fed conditions can be achieved by improving plant traits such as efficient water mining (by superior root characters) and cellular-level tolerance mechanisms. Pyramiding these drought-adaptive traits by simultaneous expression of genes regulating drought-adaptive mechanisms has phenomenal relevance in improving stress tolerance. In this study, we provide evidence that peanut transgenic plants expressing Alfalfa zinc finger 1 (Alfin1), a root growth-associated transcription factor gene, Pennisetum glaucum heat-shock factor (PgHSF4) and Pea DNA helicase (PDH45) involved in protein turnover and protection showed improved tolerance, higher growth and productivity under drought stress conditions. Stable integration of all the transgenes was noticed in transgenic lines. The transgenic lines showed higher root growth, cooler crop canopy air temperature difference (less CCATD) and higher relative water content (RWC) under drought stress. Low proline levels in transgenic lines substantiate the maintenance of higher water status. The survival and recovery of transgenic lines was significantly higher under gradual moisture stress conditions with higher biomass. Transgenic lines also showed significant tolerance to ethrel-induced senescence and methyl viologen-induced oxidative stress. Several stress-responsive genes such as heat-shock proteins (HSPs), RING box protein-1 (RBX1), Aldose reductase, late embryogenesis abundant-5 (LEA5) and proline-rich protein-2 (PRP2), a gene involved in root growth, showed enhanced expression under stress in transgenic lines. Thus, the simultaneous expression of regulatory genes contributing for drought-adaptive traits can improve crop adaptation and productivity under water-limited conditions
Higgs and SUSY searches at future colliders
In this talk, I discuss some aspects of Higgs searches at future colliders,
particularly comparing and contrasting the capabilities of LHC and Next Linear
Collider (NLC), including the aspects of Higgs searches in supersymmetric
theories. After this, I will discuss how the search and study of sparticles
other than the Higgs can give information about the parameters of the Minimal
Supersymmetric Standard Model (MSSM).Comment: 20 pages, 12 figures, laTeX, requires pramana.sty,ias.sty added. In
the Proceedings of XII DAE symposium, Chandigarh, December 199
On measurement of top polarization as a probe of production mechanisms at the LHC
In this note we demonstrate the use of top polarization in the study of resonances at the LHC, in the possible case where the dynamics implies
a non-zero top polarization. As a probe of top polarization we construct an
asymmetry in the decay-lepton azimuthal angle distribution (corresponding to
the sign of ) in the laboratory. The asymmetry is non-vanishing
even for a symmetric collider like the LHC, where a positive axis is not
uniquely defined. The angular distribution of the leptons has the advantage of
being a faithful top-spin analyzer, unaffected by possible anomalous
couplings, to linear order. We study, for purposes of demonstration, the case
of a as might exist in the little Higgs models. We identify kinematic cuts
which ensure that our asymmetry reflects the polarization in sign and
magnitude. We investigate possibilities at the LHC with two energy options:
TeV and TeV, as well as at the Tevatron. At the
LHC the model predicts net top quark polarization of the order of a few per
cent for GeV, being as high as for a smaller mass
of the of GeV and for the largest allowed coupling in the model, the
values being higher for the TeV option. These polarizations translate to a
deviation from the standard-model value of azimuthal asymmetry of up to about
() for () TeV LHC, whereas for the Tevatron, values as high as
are attained. For the TeV LHC with an integrated luminosity of 10
fb, these numbers translate into a sensitivity over a large
part of the range GeV.Comment: 28 page, LaTeX, requires JHEP style file, 12 figures. Typos corrected
and references adde
A Large Hadron Electron Collider at CERN
This document provides a brief overview of the recently published report on
the design of the Large Hadron Electron Collider (LHeC), which comprises its
physics programme, accelerator physics, technology and main detector concepts.
The LHeC exploits and develops challenging, though principally existing,
accelerator and detector technologies. This summary is complemented by brief
illustrations of some of the highlights of the physics programme, which relies
on a vastly extended kinematic range, luminosity and unprecedented precision in
deep inelastic scattering. Illustrations are provided regarding high precision
QCD, new physics (Higgs, SUSY) and electron-ion physics. The LHeC is designed
to run synchronously with the LHC in the twenties and to achieve an integrated
luminosity of O(100) fb. It will become the cleanest high resolution
microscope of mankind and will substantially extend as well as complement the
investigation of the physics of the TeV energy scale, which has been enabled by
the LHC
Hidden magnetic states emergent under electric field, in a room temperature composite magnetoelectric multiferroic
The ability to control a magnetic phase with an electric field is of great current interest for a variety of low power electronics in which the magnetic state is used either for information storage or logic operations. Over the past several years, there has been a considerable amount of research on pathways to control the direction of magnetization with an electric field. More recently, an alternative pathway involving the change of the magnetic state (ferromagnet to antiferromagnet) has been proposed. In this paper, we demonstrate electric field control of the Anomalous Hall Transport in a metamagnetic FeRh thin film, accompanying an antiferromagnet (AFM) to ferromagnet (FM) phase transition. This approach provides us with a pathway to "hide" or "reveal" a given ferromagnetic region at zero magnetic field. By converting the AFM phase into the FM phase, the stray field, and hence sensitivity to external fields, is decreased or eliminated. Using detailed structural analyses of FeRh films of varying crystalline quality and chemical order, we relate the direct nanoscale origins of this memory effect to site disorder as well as variations of the net magnetic anisotropy of FM nuclei. Our work opens pathways toward a new generation of antiferromagnetic - ferromagnetic interactions for spintronics
Summary of the Activities of the Working Group I on High Energy and Collider Physics
This is a summary of the projects undertaken by the Working Group I on High
Energy Collider Physics at the Eighth Workshop on High Energy Physics
Phenomenology (WHEPP8) held at the Indian Institute of Technology, Mumbai,
January 5-16, 2004. The topics covered are (i) Higgs searches (ii)
supersymmetry searches (iii) extra dimensions and (iv) linear collider.Comment: summary of Working Group I at the Eighth Workshop on High Energy
Physics Phenomenology (WHEPP8), I.I.T., Mumbai, January 5-16, 200
Theoretical expectations for total cross-sections at the large hadron collider
In this note, we summarize and compare various model predictions for
total cross-section , giving an estimate of the range of
predictions for the total cross-section, expected at
the LHC. We concentrate on the results for \sigma_{\tot}^{pp} obtained in a
particular QCD based model of the energy dependence of the total cross-section,
including the effect of soft gluon radiation. We obtain the range of
predictions in this model by exploring the allowed range of model parameters.
We further give a handy parametrisation of these results which incidentally
spans the range of various other available predictions at the LHC as well.Comment: 12 pages, 6 figures, laTeX, requires ias.cls, ias.sty include
Sustained platelet-sparing effect of weekly low dose paclitaxel allows effective, tolerable delivery of extended dose dense weekly carboplatin in platinum resistant/refractory epithelial ovarian cancer
Background: Platinum agents have shown demonstrable activity in the treatment of patients with platinum resistant, recurrent ovarian cancer when delivered in a "dose-dense" fashion. However, the development of thrombocytopenia limits the weekly administration of carboplatin to no greater than AUC 2. Paclitaxel has a well-described platelet sparing effect however its use to explicitly provide thromboprotection in the context of dose dense carboplatin has not been explored. Methods: We treated seven patients with platinum resistant ovarian cancer who had previously received paclitaxel or who had developed significant peripheral neuropathy precluding the use of further full dose weekly paclitaxel. Results: We were able to deliver carboplatin AUC 3 and paclitaxel 20 mg/m(2) with no thrombocytopenia or worsening of neuropathic side-effects, and with good activity. Conclusions: We conclude that this regimen may be feasible and active, and could be formally developed as a "platinum-focussed dose-dense scaffold" into which targeted therapies that reverse platinum resistance can be incorporated, and merits further evaluation
A cost effectiveness analysis of the preferred antidotes for acute paracetamol poisoning patients in Sri Lanka
Background: Acute paracetamol poisoning is a rapidly increasing problem in Sri Lanka. The antidotes are expensive and yet no health economic evaluation has been done on the therapy for acute paracetamol poisoning in the developing world. The aim of this study is to determine the cost effectiveness of using N-acetylcysteine over methionine in the management of acute paracetamol poisoning in Sri Lanka. Methods:Economic analysis was applied using public healthcare system payer perspective. Costs were obtained from a series of patients admitted to the National Hospital of Sri Lanka with a history of acute paracetamol overdose. Evidence on effectiveness was obtained from a systematic review of the literature. Death due to hepatotoxicity was used as the primary outcome of interest. Analysis and development of decision tree models was done using Tree Age Pro 2008. Results: An affordable treatment threshold of Sri Lankan rupees 1,537,120/death prevented was set from the expected years of productive life gained and the average contribution to GDP. A cost-minimisation analysis was appropriate for patients presenting within 10 hours and methionine was the least costly antidote. For patients presenting 10-24 hours after poisoning, n-acetylcysteine was more effective and the incremental cost effectiveness ratio of Sri Lankan rupees 316,182/life saved was well under the threshold. One-way and multi-way sensitivity analysis also supported methionine for patients treated within 10 hours and n-acetylcysteine for patients treated within 10-24 hours as preferred antidotes.Conclusions: Post ingestion time is an important determinant of preferred antidotal therapy for acute paracetamol poisoning patients in Sri Lanka. Using n-acetylcysteine in all patients is not cost effective. On economic grounds, methionine should become the preferred antidote for Sri Lankan patients treated within 10 hours of the acute ingestion and n-acetylcysteine should continue to be given to patients treated within 10-24 hours
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