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Decision management for the Hanford Environmental Dose Reconstruction Project
The Hanford Environmental Dose Reconstruction (HEDR) Project is in the process of developing estimates for the radiation doses that individuals and population groups may have received as a result of past activities at the Hanford Reservation in Eastern Washington. A formal decision-aiding methodology has been developed to assist the HEDR Project in making significant and defensible decisions regarding how this study will be conducted. These decisions relate primarily to policy (e.g., the appropriate level of public participation in the study) and specific technical aspects (e.g., the appropriate domain and depth of the study), and may have significant consequences with respect to technical results, costs, and public acceptability
Design of beam optics for the Future Circular Collider e+e- -collider rings
A beam optics scheme has been designed for the Future Circular Collider-e+e-
(FCC-ee). The main characteristics of the design are: beam energy 45 to 175
GeV, 100 km circumference with two interaction points (IPs) per ring,
horizontal crossing angle of 30 mrad at the IP and the crab-waist scheme [1]
with local chromaticity correction. The crab-waist scheme is implemented within
the local chromaticity correction system without additional sextupoles, by
reducing the strength of one of the two sextupoles for vertical chromatic
correction at each side of the IP. So-called "tapering" of the magnets is
applied, which scales all fields of the magnets according to the local beam
energy to compensate for the effect of synchrotron radiation (SR) loss along
the ring. An asymmetric layout near the interaction region reduces the critical
energy of SR photons on the incoming side of the IP to values below 100 keV,
while matching the geometry to the beam line of the FCC proton collider
(FCC-hh) [2] as closely as possible. Sufficient transverse/longitudinal dynamic
aperture (DA) has been obtained, including major dynamical effects, to assure
an adequate beam lifetime in the presence of beamstrahlung and top-up
injection. In particular, a momentum acceptance larger than +/-2% has been
obtained, which is better than the momentum acceptance of typical collider
rings by about a factor of 2. The effects of the detector solenoids including
their compensation elements are taken into account as well as synchrotron
radiation in all magnets. The optics presented in this paper is a step toward a
full conceptual design for the collider. A number of issues have been
identified for further study
Esophageal sphincter device for gastroesophageal reflux disease
BACKGROUND Patients with gastroesophageal reflux disease who have a partial response to proton-pump inhibitors often seek alternative therapy. We evaluated the safety and effectiveness of a new magnetic device to augment the lower esophageal sphincter. METHODS We prospectively assessed 100 patients with gastroesophageal reflux disease before and after sphincter augmentation. The study did not include a concurrent control group. The primary outcome measure was normalization of esophageal acid exposure or a 50% or greater reduction in exposure at 1 year. Secondary outcomes were 50% or greater improvement in quality of life related to gastroesophageal reflux disease and a 50% or greater reduction in the use of proton-pump inhibitors at 1 year. For each outcome, the prespecified definition of successful treatment was achievement of the outcome in at least 60% of the patients. The 3-year results of a 5-year study are reported. RESULTS The primary outcome was achieved in 64% of patients (95% confidence interval [CI], 54 to 73). For the secondary outcomes, a reduction of 50% or more in the use of proton-pump inhibitors occurred in 93% of patients, and there was improvement of 50% or more in quality-of-life scores in 92%, as compared with scores for patients assessed at baseline while they were not taking proton-pump inhibitors. The most frequent adverse event was dysphagia (in 68% of patients postoperatively, in 11% at 1 year, and in 4% at 3 years). Serious adverse events occurred in six patients, and in six patients the device was removed. CONCLUSIONS In this single-group evaluation of 100 patients before and after sphincter augmentation with a magnetic device, exposure to esophageal acid decreased, reflux symptoms improved, and use of proton-pump inhibitors decreased. Follow-up studies are needed to assess long-term safety. (Funded by Torax Medical; ClinicalTrials.gov number, NCT00776997.
Constraints on the intergalactic magnetic field using Fermi-LAT and H.E.S.S. blazar observations
Magnetic fields in galaxies and galaxy clusters are believed to be the result
of the amplification of intergalactic seed fields during the formation of
large-scale structures in the universe. However, the origin, strength, and
morphology of this intergalactic magnetic field (IGMF) remain unknown. Lower
limits on (or indirect detection of) the IGMF can be obtained from observations
of high-energy gamma rays from distant blazars. Gamma rays interact with the
extragalactic background light to produce electron-positron pairs, which can
subsequently initiate electromagnetic cascades. The -ray signature of
the cascade depends on the IGMF since it deflects the pairs. Here we report on
a new search for this cascade emission using a combined data set from the Fermi
Large Area Telescope and the High Energy Stereoscopic System. Using
state-of-the-art Monte Carlo predictions for the cascade signal, our results
place a lower limit on the IGMF of G for a coherence
length of 1 Mpc even when blazar duty cycles as short as 10 yr are assumed.
This improves on previous lower limits by a factor of 2. For longer duty cycles
of () yr, IGMF strengths below G
( G) are excluded, which rules out specific models for IGMF
generation in the early universe.Comment: 20 pages, 7 figures, 4 tables. Accepted for publication in ApJ
Letters. Auxiliary data is provided in electronic format at
https://zenodo.org/record/801431
Detection of extended gamma-ray emission around the Geminga pulsar with H.E.S.S
Geminga is an enigmatic radio-quiet gamma-ray pulsar located at a mere 250 pc
distance from Earth. Extended very-high-energy gamma-ray emission around the
pulsar was discovered by Milagro and later confirmed by HAWC, which are both
water Cherenkov detector-based experiments. However, evidence for the Geminga
pulsar wind nebula in gamma rays has long evaded detection by imaging
atmospheric Cherenkov telescopes (IACTs) despite targeted observations. The
detection of gamma-ray emission on angular scales > 2 deg poses a considerable
challenge for the background estimation in IACT data analysis. With recent
developments in understanding the complementary background estimation
techniques of water Cherenkov and atmospheric Cherenkov instruments, the
H.E.S.S. IACT array can now confirm the detection of highly extended gamma-ray
emission around the Geminga pulsar with a radius of at least 3 deg in the
energy range 0.5-40 TeV. We find no indications for statistically significant
asymmetries or energy-dependent morphology. A flux normalisation of
cmsTeV at 1 TeV is obtained
within a 1 deg radius region around the pulsar. To investigate the particle
transport within the halo of energetic leptons around the pulsar, we fitted an
electron diffusion model to the data. The normalisation of the diffusion
coefficient obtained of
cms, at an electron energy of 100 TeV, is compatible with values
previously reported for the pulsar halo around Geminga, which is considerably
below the Galactic average.Comment: 16 pages, 15 figures, 7 tables. Accepted for publication in Astronomy
& Astrophysic
HESS J1809193: a halo of escaped electrons around a pulsar wind nebula?
Context. HESS J1809193 is an unassociated very-high-energy -ray
source located on the Galactic plane. While it has been connected to the nebula
of the energetic pulsar PSR J18091917, supernova remnants and molecular
clouds present in the vicinity also constitute possible associations. Recently,
the detection of -ray emission up to energies of 100 TeV with the
HAWC observatory has led to renewed interest in HESS J1809193.
Aims. We aim to understand the origin of the -ray emission of HESS
J1809193.
Methods. We analysed 93.2 h of data taken on HESS J1809193 above 0.27 TeV
with the High Energy Stereoscopic System (H.E.S.S.), using a multi-component,
three-dimensional likelihood analysis. In addition, we provide a new analysis
of 12.5 yr of Fermi-LAT data above 1 GeV within the region of HESS J1809193.
The obtained results are interpreted in a time-dependent modelling framework.
Results. For the first time, we were able to resolve the emission detected
with H.E.S.S. into two components: an extended component that exhibits a
spectral cut-off at 13 TeV, and a compact component that is located close
to PSR J18091917 and shows no clear spectral cut-off. The Fermi-LAT analysis
also revealed extended -ray emission, on scales similar to that of the
extended H.E.S.S. component.
Conclusions. Our modelling indicates that based on its spectrum and spatial
extent, the extended H.E.S.S. component is likely caused by inverse Compton
emission from old electrons that form a halo around the pulsar wind nebula. The
compact component could be connected to either the pulsar wind nebula or the
supernova remnant and molecular clouds. Due to its comparatively steep
spectrum, modelling the Fermi-LAT emission together with the H.E.S.S.
components is not straightforward. (abridged)Comment: 14 pages, 10 figures. Accepted for publication in A&A. Corresponding
authors: Vikas Joshi, Lars Mohrman
HE-LHC: The High-Energy Large Hadron Collider – Future Circular Collider Conceptual Design Report Volume 4
In response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC study covered an energy-frontier hadron collider (FCC-hh), a highest-luminosity high-energy lepton collider (FCC-ee), the corresponding 100 km tunnel infrastructure, as well as the physics opportunities of these two colliders, and a high-energy LHC, based on FCC-hh technology. This document constitutes the third volume of the FCC Conceptual Design Report, devoted to the hadron collider FCC-hh. It summarizes the FCC-hh physics discovery opportunities, presents the FCC-hh accelerator design, performance reach, and staged operation plan, discusses the underlying technologies, the civil engineering and technical infrastructure, and also sketches a possible implementation. Combining ingredients from the Large Hadron Collider (LHC), the high-luminosity LHC upgrade and adding novel technologies and approaches, the FCC-hh design aims at significantly extending the energy frontier to 100 TeV. Its unprecedented centre-of-mass collision energy will make the FCC-hh a unique instrument to explore physics beyond the Standard Model, offering great direct sensitivity to new physics and discoveries
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