Ablation sensor

Sensor device with switches for measuring surface recession of charring and noncharring ablator

Reply To "comment On 'photoionization Of Helium Atoms Irradiated With Intense Vacuum Ultraviolet Free-electron Laser Light. Part I. Experimental Study Of Multiphoton And Single-photon Processes'"

We do not agree with the conclusion of the Comment by Charalambidis questioning our observation of two-photon ionization of helium by intense radiation with 13 eV photons from a vuv free-electron laser. Two-photon ionization is clearly established by the detection of low-energy photoelectrons at ∼1.7 eV, which agrees very well with the expected energy for a two-photon ionization process. © 2006 The American Physical Society.743Laarmann, T., De Castro, A.R.B., Schulz, J., Wabnitz, H., Möller, T., (2005) Phys. Rev. A, 72, p. 023409. , PLRAAN. 1050-2947. 10.1103/PhysRevA.72.023409Ayvazyan, V., Baboi, N., Bohnet, I., Brinkmann, R., Castellano, M., Castro, P., Catani, L., Zapfe, K., (2002) Phys. Rev. Lett., 88, p. 104802. , PRLTAO. 0031-9007. 10.1103/PhysRevLett.88.104802Ayvazyan, V., Baboi, N., Bähr, J., Balandin, V., Beutner, B., Brandt, A., Bohnet, I., Schreiber H, -J., (2006) Eur. Phys. J. D, 37, p. 297. , EPJDF6. 1434-6060. 10.1140/epjd/e2005-00308-1Wabnitz, H., Bittner, L., De Castro, A.R.B., Döhrmann, R., Gürtler, P., Laarmann, T., Laasch, W., Yurkov, M., (2002) Nature (London), 420, p. 482. , NATUAS. 0028-0836. 10.1038/nature01197Laarmann, T., De Castro, A.R.B., Gürtler, P., Laasch, W., Schulz, J., Wabnitz, H., Möller, T., (2004) Phys. Rev. Lett., 92, p. 143401. , PRLTAO. 0031-9007. 10.1103/PhysRevLett.92.143401Laarmann, T., Rusek, M., Wabnitz, H., Schulz, J., De Castro, A.R.B., Gürtler, P., Laasch, W., Möller, T., (2005) Phys. Rev. Lett., 95, p. 063402. , PRLTAO. 0031-9007. 10.1103/PhysRevLett.95.063402Wabnitz, H., De Castro, A.R.B., Gürtler, P., Laarmann, T., Laasch, W., Schulz, J., Möller, T., (2005) Phys. Rev. Lett., 94, p. 023001. , PRLTAO. 0031-9007. 10.1103/PhysRevLett.94.023001Santra, R., Greene, C.H., (2004) Phys. Rev. A, 70, p. 053401. , PLRAAN 1050-2947 10.1103/PhysRevA.70.053401Tzallas, P., Charalambidis, D., Papadogiannis, N.A., Witte, K., Tsakiris, G.D., (2003) Nature (London), 426, p. 267. , NATUAS 0028-0836 10.1038/nature02091Papadogiannis, N.A., Nikolopoulos, L.A.A., Charalambidis, D., Tsakiris, G.D., Tzallas, P., Witte, K., (2003) Appl. Phys. B, 76, p. 721. , APDOEM 0946-2171Papadogiannis, N.A., Nikolopoulos, L.A.A., Charalambidis, D., Tsakiris, G.D., Tzallas, P., Witte, K., (2003) Phys. Rev. Lett., 90, p. 133902. , PRLTAO 0031-9007 10.1103/PhysRevLett.90.133902De Castro, A.R.B., Laarmann, T., Schulz, J., Wabnitz, H., Möller, T., (2005) Phys. Rev. A, 72, p. 023410. , PLRAAN. 1050-2947. 10.1103/PhysRevA.72.02341

Radiation spectra of laser-driven quantum relativistic electrons

A procedure to calculate the radiation spectrum emitted by an arbitrarily prepared Dirac wave packet is developed. It is based on the Dirac charge current and classical electrodynamic theory. Apart from giving absolute intensity values, it is exact in terms of relativistic retardation effects and angular dependence. We employ a laser driven free electron to demonstrate the advantages of our method as compared to traditional ones that merely rely on the Fourier transform of the dipole operator's expectation value. Classical reference calculations confirm the results obtained for the low-frequency part of the spectrum, especially in terms of the observed red-shifts, which clearly deviate from non-relativistic calculations. In the high-frequency part of the spectrum, we note appreciable deviations to the purely classical calculations which may be linked to quantum averaging effects.Comment: 30 pages, 7 figure

Vector meson electromagnetic form factors

The charge, magnetic and quadrupole form factors of vector mesons and the charge form factor of pseudo-scalar mesons are calculated in quenched lattice QCD. The charge radii and magnetic moments are derived. The quark sector contributions to the form factors are calculated separately and we highlight the environmental sensitivity of the light-quark contribution to charge radii.QCDSF Collaboration: M. Gürtler, D. Brömmel, M. Göckeler, Ph. Hägler, R. Horsley, Y. Nakamura, D. Pleiter, P.E.L. Rakow, A. Schäfer, G. Schierholz, H. Stüben and J.M. Zanott

The costs of preventing and treating chagas disease in Colombia

Background: The objective of this study is to report the costs of Chagas disease in Colombia, in terms of vector disease control programmes and the costs of providing care to chronic Chagas disease patients with cardiomyopathy. Methods: Data were collected from Colombia in 2004. A retrospective review of costs for vector control programmes carried out in rural areas included 3,084 houses surveyed for infestation with triatomine bugs and 3,305 houses sprayed with insecticide. A total of 63 patient records from 3 different hospitals were selected for a retrospective review of resource use. Consensus methodology with local experts was used to estimate care seeking behaviour and to complement observed data on utilisation. Findings: The mean cost per house per entomological survey was $4.4 (in US$ of 2004), whereas the mean cost of spraying a house with insecticide was $27. The main cost driver of spraying was the price of the insecticide, which varied greatly. Treatment of a chronic Chagas disease patient costs between$46.4 and $7,981 per year in Colombia, depending on severity and the level of care used. Combining cost and utilisation estimates the expected cost of treatment per patient-year is$1,028, whereas lifetime costs averaged $11,619 per patient. Chronic Chagas disease patients have limited access to healthcare, with an estimated 22% of patients never seeking care. Conclusion: Chagas disease is a preventable condition that affects mostly poor populations living in rural areas. The mean costs of surveying houses for infestation and spraying infested houses were low in comparison to other studies and in line with treatment costs. Care seeking behaviour and the type of insurance affiliation seem to play a role in the facilities and type of care that patients use, thus raising concerns about equitable access to care. Preventing Chagas disease in Colombia would be cost-effective and could contribute to prevent inequalities in health and healthcare.Wellcome Trus

Diffraction-limited ultrabroadband terahertz spectroscopy

Diffraction is the ultimate limit at which details of objects can be resolved in conventional optical spectroscopy and imaging systems. In the THz spectral range, spectroscopy systems increasingly rely on ultra-broadband radiation (extending over more 5 octaves) making a great challenge to reach resolution limited by diffraction. Here, we propose an original easy-to-implement wavefront manipulation concept to achieve ultrabroadband THz spectroscopy system with diffraction-limited resolution. Applying this concept to a large-area photoconductive emitter, we demonstrate diffraction-limited ultra-broadband spectroscopy system up to 14.5 THz with a dynamic range of 103. The strong focusing of ultrabroadband THz radiation provided by our approach is essential for investigating single micrometer-scale objects such as graphene flakes or living cells, and besides for achieving intense ultra-broadband THz electric fields

Baryogenesis from Primordial Blackholes after Electroweak Phase Transition

Incorporating a realistic model for accretion of ultra-relativistic particles by primordial blackholes (PBHs), we study the evolution of an Einstein-de Sitter universe consisting of PBHs embedded in a thermal bath from the epoch $\sim 10^{-33}$ sec to $\sim 5\times 10^{-9}$ sec. In this paper we use Barrow et al's ansatz to model blackhole evaporation in which the modified Hawking temperature goes to zero in the limit of the blackhole attaining a relic state with mass $\sim m_{pl}$. Both single mass PBH case as well as the case in which blackhole masses are distributed in the range $8\times 10^2 - 3\times 10^5$ gm have been considered in our analysis. Blackholes with mass larger than $\sim 10^5$ gm appear to survive beyond the electroweak phase transition and, therefore, successfully manage to create baryon excess via $X-\bar X$ emissions, averting the baryon number wash-out due to sphalerons. In this scenario, we find that the contribution to the baryon-to-entropy ratio by PBHs of initial mass $m$ is given by $\sim \epsilon \zeta (m/1 {gm})^{-1}$, where $\epsilon$ and $\zeta$ are the CP-violating parameter and the initial mass fraction of the PBHs, respectively. For $\epsilon$ larger than $\sim 10^{-4}$, the observed matter-antimatter asymmetry in the universe can be attributed to the evaporation of PBHs.Comment: Latex2e file with seven figures included as postscript file

A novel WFS1 mutation in a family with dominant low frequency sensorineural hearing loss with normal VEMP and EcochG findings

Background: Low frequency sensorineural hearing loss (LFSNHL) is an uncommon clinical finding. Mutations within three different identified genes (DIAPH1, MYO7A, and WFS1) are known to cause LFSNHL. The majority of hereditary LFSNHL is associated with heterozygous mutations in the WFS1 gene (wolframin protein). The goal of this study was to use genetic analysis to determine if a small American family's hereditary LFSNHL is linked to a mutation in the WFS1 gene and to use VEMP and EcochG testing to further characterize the family's audiovestibular phenotype. Methods: The clinical phenotype of the American family was characterized by audiologic testing, vestibular evoked myogenic potentials (VEMP), and electrocochleography (EcochG) evaluation. Genetic characterization was performed by microsatellite analysis and direct sequencing of WFS1 for mutation detection. Results: Sequence analysis of the WFS1 gene revealed a novel heterozygous mutation at c.2054G>C predicting a p.R685P amino acid substitution in wolframin. The c.2054G>C mutation segregates faithfully with hearing loss in the family and is absent in 230 control chromosomes. The p.R685 residue is located within the hydrophilic C-terminus of wolframin and is conserved across species. The VEMP and EcochG findings were normal in individuals segregating the WFS1 c.2054G>C mutation. Conclusion: We discovered a novel heterozygous missense mutation in exon 8 of WFS1 predicting a p.R685P amino acid substitution that is likely to underlie the LFSNHL phenotype in the American family. For the first time, we describe VEMP and EcochG findings for individuals segregating a heterozygous WFS1 mutation.NIH grants DC04945 (V.A.S), DC006901 (V.A.S.) and P30 DC04661 (V.M. Bloedel Core)

A Field Trial of Alternative Targeted Screening Strategies for Chagas Disease in Arequipa, Peru

In the wake of emerging T. cruzi infection in children of periurban Arequipa, Peru, we conducted a prospective field trial to evaluate alternative targeted screening strategies for Chagas disease across the city. Using insect vector data that is routinely collected during Ministry of Health insecticide application campaigns in 3 periurban districts of Arequipa, we separated into 4 categories those households with 1) infected vectors; 2) high vector densities; 3) low vector densities; and 4) no vectors. Residents of all infected-vector households and a random sample of those in the other 3 categories were invited for serological screening for T. cruzi infection. Subsequently, all residents of households within a 15-meter radius of detected seropositive individuals were invited to be screened in a ring case-detection scheme. Of 923 participants, 21 (2.28%) were seropositive. There were no significant differences in prevalence across the 4 screening strategies, indicating that household entomologic factors alone could not predict the risk of infection. Indeed, the most predictive variable of infection was the number of years a person lived in a location with triatomine insects. Therefore, a simple residence history questionnaire may be a useful screening tool in large, diverse urban environments with emerging Chagas disease