25 research outputs found
Beyond the Pixel: a Photometrically Calibrated HDR Dataset for Luminance and Color Prediction
Light plays an important role in human well-being. However, most computer
vision tasks treat pixels without considering their relationship to physical
luminance. To address this shortcoming, we introduce the Laval Photometric
Indoor HDR Dataset, the first large-scale photometrically calibrated dataset of
high dynamic range 360{\deg} panoramas. Our key contribution is the calibration
of an existing, uncalibrated HDR Dataset. We do so by accurately capturing RAW
bracketed exposures simultaneously with a professional photometric measurement
device (chroma meter) for multiple scenes across a variety of lighting
conditions. Using the resulting measurements, we establish the calibration
coefficients to be applied to the HDR images. The resulting dataset is a rich
representation of indoor scenes which displays a wide range of illuminance and
color, and varied types of light sources. We exploit the dataset to introduce
three novel tasks, where: per-pixel luminance, per-pixel color and planar
illuminance can be predicted from a single input image. Finally, we also
capture another smaller photometric dataset with a commercial 360{\deg} camera,
to experiment on generalization across cameras. We are optimistic that the
release of our datasets and associated code will spark interest in physically
accurate light estimation within the community. Dataset and code are available
at https://lvsn.github.io/beyondthepixel/
The use of muscle strength assessed with handheld dynamometers as a non-invasive biological marker in myotonic dystrophy type 1 patients: a multicenter study
<p>Abstract</p> <p>Background</p> <p>Myotonic dystrophy type 1 (DM1) is a multisystem disorder that demonstrates variable symptoms and rates of progression. Muscle weakness is considered one of the main problems with a clinical picture that is characterized by distal weakness of the limbs progressing to proximal weakness. The main objective of this study was to characterize the maximal strength of ankle eversion and dorsiflexion in DM1 patients. Manual and handheld dynamometer (HHD) muscle testing were also compared.</p> <p>Methods</p> <p>The maximal strength of 22 patients from Quebec (mean age = 41,1 ± 13,8) and 24 from Lyon (mean age = 41,6 ± 10,2) were compared to 16 matched controls.</p> <p>Results</p> <p>With the use of HHD, an excellent reproducibility of the torque measurements was obtained for both centers in eversion (R<sup>2 </sup>= 0,94/Quebec; 0,89/Lyon) and dorsiflexion (R<sup>2 </sup>= 0,96/Quebec; 0,90/Lyon). The differences between 3 groups of DM1 (mild, moderate, severe) and between them and controls were all statistically significant (p < 0,001). No statistical differences between sites were observed (p > 0.05). The degree of muscle strength decline in dorsiflexion (eversion) were 60% (47%), 77% (71%), and 87% (83%) for DM1 with mild, moderate, and severe impairments, respectively. The smallest mean difference between all DM1 patients taking together was 2.3 Nm, a difference about twice than the standard error of measurement. There was a strong relationship between eversion and dorsiflexion strength profiles (R<sup>2 </sup>= 0,87;Quebec/0,80;Lyon). Using a 10-point scale, manual muscle testing could not discriminate between the 3 groups of DM1 patients.</p> <p>Conclusions</p> <p>The HHD protocol showed discriminative properties suitable for multicentre therapeutic trial. The present results confirmed the capacity of quantitative muscle testing to discriminate between healthy and DM1 patients with different levels of impairments. This study is a preliminary step for the implementation of a valid, reliable and responsive clinical outcome for the measurement of muscle impairments with this population.</p
Dossier. La relation philosophie-théologie hier et aujourd’hui
Avant-propos Le présent dossier réunit quelques-unes des contributions données lors de la séance académique organisée à l’Institut de France (Paris) le 9 décembre 2011, à l’occasion de la publication de l’Anthologie Philosophie et théologie (4 tomes) achevée en 2011 aux éditions du Cerf sous la direction de Philippe Capelle-Dumont, en collaboration avec Jean Greisch et Geneviève Hébert (Tome IV), Jean-Christophe Bardout (Tome III), Olivier Boulnois (Tome II), Jérôme Alexandre (Tome I) et de 9..
Comparison between fused silica of type II and III after surface heating with a CO2 laser
International audienc
Global Regulation of the Response to Sulfur Availability in the Cheese-Related Bacterium Brevibacterium aurantiacumâ–ż â€
In this study, we combined metabolic reconstruction, growth assays, and metabolome and transcriptome analyses to obtain a global view of the sulfur metabolic network and of the response to sulfur availability in Brevibacterium aurantiacum. In agreement with the growth of B. aurantiacum in the presence of sulfate and cystine, the metabolic reconstruction showed the presence of a sulfate assimilation pathway, thiolation pathways that produce cysteine (cysE and cysK) or homocysteine (metX and metY) from sulfide, at least one gene of the transsulfuration pathway (aecD), and genes encoding three MetE-type methionine synthases. We also compared the expression profiles of B. aurantiacum ATCC 9175 during sulfur starvation or in the presence of sulfate. Under sulfur starvation, 690 genes, including 21 genes involved in sulfur metabolism and 29 genes encoding amino acids and peptide transporters, were differentially expressed. We also investigated changes in pools of sulfur-containing metabolites and in expression profiles after growth in the presence of sulfate, cystine, or methionine plus cystine. The expression of genes involved in sulfate assimilation and cysteine synthesis was repressed in the presence of cystine, whereas the expression of metX, metY, metE1, metE2, and BL613, encoding a probable cystathionine-Îł-synthase, decreased in the presence of methionine. We identified three ABC transporters: two operons encoding transporters were transcribed more strongly during cysteine limitation, and one was transcribed more strongly during methionine depletion. Finally, the expression of genes encoding a methionine Îł-lyase (BL929) and a methionine transporter (metPS) was induced in the presence of methionine in conjunction with a significant increase in volatile sulfur compound production