13 research outputs found
Highly cross-linked polymeric capillary monoliths for the separation of low, medium, and high molecular weight analytes
Individual olfactory sensory neurons project into more than one glomerulus inXenopus laevis tadpole olfactory bulb
Quantitative assessment of the effect of basis set superposition error on the electron density of molecular complexes by means of quantum molecular similarity measures
Evolution of amino acids and biogenic amines in natural ciders as a function of the year and the manufacture steps
Biogenic Amine Content of Shalgam (Ĺžalgam): A Traditional Lactic Acid Fermented Turkish Beverage
Response profiles to amino acid odorants of olfactory glomeruli in larval Xenopus laevis
Glomeruli in the vertebrate olfactory bulb (OB) appear as anatomically discrete modules receiving direct input from the olfactory epithelium (OE) via axons of olfactory receptor neurons (ORNs). The response profiles with respect to amino acids (AAs) of a large number of ORNs in larval Xenopus laevis have been recently determined and analysed. Here we report on Ca2+ imaging experiments in a nose–brain preparation of the same species at the same developmental stages. We recorded responses to AAs of glomeruli in the OB and determined the response profiles to AAs of individual glomeruli. We describe the general features of AA-responsive glomeruli and compare their response profiles to AAs with those of ORNs obtained in our previous study. A large number of past studies have focused either on odorant responses in the OE or on odorant-induced responses in the OB. However, a thorough comparison of odorant-induced responses of both stages, ORNs and glomeruli of the same species is as yet lacking. The glomerular response profiles reported herein markedly differ from the previously obtained response profiles of ORNs in that glomeruli clearly have narrower selectivity profiles than ORNs. We discuss possible explanations for the different selectivity profiles of glomeruli and ORNs in the context of the development of the olfactory map