32 research outputs found
Seizure and cognitive outcomes after resection of glioneuronal tumors in children
- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/01/2018
- Field of study
Objective: Glioneuronal tumors (GNTs) are wellârecognized causes of chronic drugâresistant focal epilepsy in children. Our practice involves an initial period of radiological surveillance and antiepileptic medications, with surgery being reserved for those with radiological progression or refractory seizures. We planned to analyze the group of patients with lowâgrade GNTs, aiming to identify factors affecting seizure and cognitive outcomes. / Methods: We retrospectively reviewed the medical records of 150 children presenting to Great Ormond Street Hospital with seizures secondary to GNTs. Analysis of clinical, neuroimaging, neuropsychological, and surgical factors was performed to determine predictors of outcome. Seizure outcome at final followâup was classified as either seizureâfree (group A) or not seizureâfree (group B) for patients with at least 12âmonths followâup postsurgery. Fullâscale intelligence quotient (FSIQ) was used as a measure of cognitive outcome. / Results: Eightyâsix males and 64 females were identified. Median presurgical FSIQ was 81. One hundred twentyâone patients (80.5%) underwent surgery. Median followâup after surgery was 2 years, with 92 patients (76%) having at least 12 months of followâup after surgery. Seventyâfour patients (80%) were seizureâfree, and 18 (20%) continued to have seizures. Radiologically demonstrated complete tumor resection was associated with higher rates of seizure freedom (P = .026). Higher presurgical FSIQ was related to shorter epilepsy duration until surgery (P = .012) and to older age at seizure onset (P = .043). / Significance: A high proportion of children who present with epilepsy and GNTs go on to have surgical tumor resection with excellent postoperative seizure control. Complete resection is associated with a higher chance of seizure freedom. Higher presurgical cognitive functioning is associated with shorter duration of epilepsy prior to surgery and with older age at seizure onset. Given the high rate of eventual surgery, early surgical intervention should be considered in children with continuing seizures associated with GNTs
Search for continuous gravitational wave emission from the Milky Way center in O3 LIGO--Virgo data
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- Publication venue
- Publication date
- 01/01/2022
- Field of study
We present a directed search for continuous gravitational wave (CW) signals
emitted by spinning neutron stars located in the inner parsecs of the Galactic
Center (GC). Compelling evidence for the presence of a numerous population of
neutron stars has been reported in the literature, turning this region into a
very interesting place to look for CWs. In this search, data from the full O3
LIGO--Virgo run in the detector frequency band [10,2000]Â Hz have been
used. No significant detection was found and 95% confidence level upper
limits on the signal strain amplitude were computed, over the full search band,
with the deepest limit of about 7.6Ă10â26 at â142Â Hz.
These results are significantly more constraining than those reported in
previous searches. We use these limits to put constraints on the fiducial
neutron star ellipticity and r-mode amplitude. These limits can be also
translated into constraints in the black hole mass -- boson mass plane for a
hypothetical population of boson clouds around spinning black holes located in
the GC.Comment: 25 pages, 5 figure
Search for subsolar-mass binaries in the first half of Advanced LIGOâs and Advanced Virgoâs third observing run
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- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2022
- Field of study
We report on a search for compact binary coalescences where at least one
binary component has a mass between 0.2 M_\odot and 1.0 M_\odot in Advanced LIGO and
Advanced Virgo data collected between 1 April 2019 1500 UTC and 1 October 2019 1500 UTC.
We extend previous analyses in two main ways: we include data from the Virgo detector and we allow for more unequal mass systems, with mass ratio q \geq 0.1.
We do not report any gravitational-wave candidates. The most significant trigger has a false alarm rate of 0.14 \mathrm{yr}^-1. This implies an upper limit on the merger rate of subsolar binaries in the range [220â24200] \mathrm{Gpc}^{-3} \, \mathrm{yr}^{-1}, depending on the chirp mass of the binary. We use this upper limit to derive astrophysical constraints on two phenomenological models that could produce subsolar-mass compact objects. One is an isotropic distribution of equal-mass primordial black holes. Using this model, we find that the fraction of dark matter in primordial black holes is f_\mathrm{PBH}\equiv \Omega_\mathrm{PBH}/\Omega_\mathrm{DM}\lesssim 6\%. The other is a dissipative dark matter model, in which fermionic dark matter can collapse and form black holes. The upper limit on the fraction of dark matter black holes depends on the minimum mass of the black holes that can be formed: the most constraining result is obtained at M_\mathrm{min}=1 M_\odot, where f_\mathrm{DBH}\equiv \Omega_\mathrm{PBH}/\Omega_\mathrm{DM}\lesssim 0.003\%. These are the tightest limits on spinning subsolar-mass binaries to date
All-sky search for gravitational wave emission from scalar boson clouds around spinning black holes in LIGO O3 data
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- Weller C. M.
- Weller R. A.
- Wellmann F.
- Wen L.
- Wessels P.
- Wette K.
- Whelan J. T.
- White D. D.
- Whiting B. F.
- Whittle C.
- Wilken D.
- Williams D.
- Williams M. J.
- Williamson A. R.
- Willis J. L.
- Willke B.
- Wilson D. J.
- Wipf C. C.
- Wlodarczyk T.
- Woan G.
- Woehler J.
- Wofford J. K.
- Wong D.
- Wong I. C. F.
- Wright M.
- Wu C.
- Wu D. S.
- Wu H.
- Wysocki D. M.
- Xiao L.
- Yamada T.
- Yamamoto H.
- Yamamoto K.
- Yamamoto T.
- Yamashita K.
- Yamazaki R.
- Yang F. W.
- Yang K. Z.
- Yang L.
- Yang Y-C
- Yang Y.
- Yang Yang
- Yap M. J.
- Yeeles D. W.
- Yeh S-W
- Yelikar A. B.
- Ying M.
- Yokoyama J.
- Yokozawa T.
- Yoo J.
- Yoshioka T.
- Yu Hang
- Yu Haocun
- Yuzurihara H.
- Zanolin M.
- Zeidler S.
- Zelenova T.
- Zendri J-P
- Zevin M.
- Zhan M.
- Zhang H.
- Zhang J.
- Zhang L.
- Zhang R.
- Zhang T.
- Zhang Y.
- Zhao C.
- Zhao G.
- Zhao Y.
- Zhao Yue
- Zhou R.
- Zhou Z.
- Zhu X. J.
- Zhu Z-H
- Zimmerman A. B.
- Zucker M. E.
- Zweizig J.
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2022
- Field of study
This paper describes the first all-sky search for long-duration, quasimonochromatic gravitational-wave signals emitted by ultralight scalar boson clouds around spinning black holes using data from the third observing run of Advanced LIGO. We analyze the frequency range from 20 to 610 Hz, over a small frequency derivative range around zero, and use multiple frequency resolutions to be robust towards possible signal frequency wanderings. Outliers from this search are followed up using two different methods, one more suitable for nearly monochromatic signals, and the other more robust towards frequency fluctuations. We do not find any evidence for such signals and set upper limits on the signal strain amplitude, the most stringent being â10â25 at around 130 Hz. We interpret these upper limits as both an âexclusion regionâ in the boson mass/black hole mass plane and the maximum detectable distance for a given boson mass, based on an assumption of the age of the black hole/boson cloud system
Real earnings management and the relevance of operating cash flows: A study of french listed firms
- Author
- A Andreas
- A Charitou
- A Habib
- A Habib
- A Zalata
- Ahmad Alqatan
- AM Zalata
- AM Zalata
- AM Zalata
- AT AltintaĆ
- AY Zang
- BA Badertscher
- BA Der
- BK Billings
- CA Finger
- CM Cupertino
- D Burgstahler
- DA Cohen
- DS Sharma
- GA Feltham
- H Byström
- H Murtini
- Hela Khemakhem-Feki
- HY Pham
- I Subekti
- JA Ohlson
- JR Graham
- KA Gunny
- KA Gunny
- LL Eng
- M Habbash
- M Spence
- MC Jensen
- ME Barth
- MF Shubita
- N Tabassum
- NA Amran
- NV Khuong
- R Fattahi
- RC Klann
- RL Watts
- S Jones
- S Mouselli
- S Roychowdhury
- SA Ross
- Saoussen Boujelben
- SC Anagnostopoulou
- SF Orpurt
- SM El-Gazzar
- SR Masoumi
- U Lel
- W Thorbecke
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10
- Author
- A Garces
- A Lemassu
- A Nobre
- A Ortalo-Magné
- AC Collins
- AD van der Woude
- AH Kolk
- AH Meijer
- AM Abdallah
- AM Abdallah
- AM Abdallah
- AM van der Sar
- Aniek D. van der Woude
- B McLaughlin
- B Zuber
- BJ Appelmelk
- C Deb
- C Hoffmann
- CA Collins
- CM Sassetti
- Coenraad P. Kuijl
- D Houben
- Daisy I. Picavet
- EJM Stoop
- EM Weerdenburg
- EM Weerdenburg
- ENG Houben
- F Carlsson
- G Delogu
- G Lamichhane
- G Prodâhom
- GB CHAPMAN
- GM Kennedy
- GR Stewart
- GS Besra
- Gunny van Stempvoort
- J De Leon
- J Geurtsen
- J Smith
- JJ GarcĂa-Vallejo
- JJ GarcĂa-Vallejo
- Jovanka Bestebroer
- Juan J. Garcia-Vallejo
- L-Y Gao
- Louis S. Ates
- LS Ates
- M Daffé
- M Di Luca
- M Harboe
- M Rosenberg
- M Sani
- M Strong
- Marcel A. Behr
- Massimiliano Maletta
- MC Lerena
- MH Daleke
- MH Daleke
- MI de Jonge
- N Korotkova
- N van der Wel
- NA Kruh
- NC Gey van Pittius
- Nicole N. van der Wel
- NN Driessen
- PJ Brennan
- PJ Brennan
- PW Hermans
- R Prados-Rosales
- R Simeone
- R Simeone
- R Wassermann
- RD Finn
- René J. P. Musters
- RO Watson
- RO Watson
- Robert van de Weerd
- S CarrĂšre-Kremer
- S Soldini
- ST Cole
- T Sambou
- TBH Geijtenbeek
- W Bitter
- Wilbert Bitter
- Y Ma
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Reconstructing the molecular life history of gliomas
- Author
- A Bagchi
- A Bagchi
- A Ernst
- A Korshunov
- A Korshunov
- A Lujambio
- A Malhotra
- A Olar
- A Perry
- A Sottoriva
- A Vestin
- AD Goldberg
- AG Knudson Jr
- AH Shain
- AK Chan
- AK Meeker
- AL Vescovi
- AM Fontebasso
- AM Olovnikov
- AP Patel
- AS Venteicher
- B Kinnersley
- B McClintock
- B McClintock
- B Vogelstein
- B Vogelstein
- B Wiestler
- BE Johnson
- BS Melin
- C Bardella
- C Bettegowda
- C Burkhard
- C Horbinski
- C Koelsche
- C Lu
- C Michaloglou
- C Telomeres Mendelian Randomization
- C Tomasetti
- CA Lovejoy
- CE Napier
- CM Counter
- CM Heaphy
- CM Heaphy
- CO Nordling
- CP Morales
- CW Greider
- D Castel
- D Clynes
- D Coppola
- D Cox
- D Gisselsson
- D Hanahan
- D Hanahan
- D Sanoudou
- D Sturm
- D Sturm
- DE Reuss
- DH Gutmann
- DJ Ashley
- DN Louis
- DN Louis
- DN Louis
- DT Jones
- DT Jones
- DW Bell
- E Huillard
- E Lazzerini-Denchi
- E Pennisi
- EC Holland
- EH Raabe
- ER Cantwell-Dorris
- Floris P. Barthel
- FP Barthel
- FW Huang
- G Cairncross
- G Ciriello
- G Schindler
- G Wu
- G Wu
- GA Rouleau
- GN Parkinson
- H Bai
- H Davies
- H Kim
- H Noushmehr
- H Ohgaki
- H Ohgaki
- H Suzuki
- H Tanaka
- H Yan
- HA Luchman
- HF van Thuijl
- I Tirosh
- J Campisi
- J Lee
- J Li
- J Maciejowski
- J Maciejowski
- J Mangerel
- J Noorbakhsh
- J Schwartzentruber
- J Vinagre
- J Wang
- J Zhang
- JD Schiffman
- JE Bromberg
- JE Eckel-Passow
- JG Cairncross
- JI Park
- JJ Kepes
- JK Lee
- JM Birch
- JM Birch
- JM Connelly
- JP Coppe
- JP Coppe
- JP Coppe
- JP Robinson
- JR Prensner
- JT Huse
- JV Forment
- JW Jeuken
- JW Shay
- JW Shay
- JZ Sanborn
- K Aihara
- K Aldape
- K Aldape
- K Chiba
- K Chiba
- K Cichowski
- K Ichimura
- K Kannan
- K Lenting
- KA McBride
- KM Turner
- KM Walsh
- KM Walsh
- KM Walsh
- KR Taylor
- L Dang
- L Hayflick
- L Maryoung
- L Uhrbom
- L Uhrbom
- LA Langford
- LR Yates
- M Ceccarelli
- M Collado
- M Collado
- M Fiscella
- M Greaves
- M Hisada
- M Kimura
- M Martini
- M Pekmezci
- M Ramamoorthy
- M Sasaki
- M Wrensch
- MA Blasco
- MA Dunham
- ME Figueroa
- MJ Law
- MJ van den Bent
- MJ Williams
- MJ Williams
- ML Suva
- N McCarthy
- N McGranahan
- N Raj
- NE Kohl
- NE Sharpless
- NL Solimini
- NW Kim
- P Buczkowicz
- P Koivunen
- P Martinez
- P Rajaraman
- P Wesseling
- P Wilcox
- PA Perez-Mancera
- PA Steck
- PC Nowell
- Pieter Wesseling
- PJ Killela
- PS Ward
- PW Lewis
- Q Wang
- R Kumar
- R Ouchi
- RA Cairns
- RB Jenkins
- RB Jenkins
- RC Stone
- RG Verhaak
- RJ Bell
- RJ OâSullivan
- RM Cawthon
- Roel G. W. Verhaak
- RS Gunny
- RS Maser
- S Azar
- S Bender
- S Courtois-Cox
- S He
- S Horn
- S Nikolaev
- S Shete
- S Turcan
- S Turcan
- S Zheng
- SE Artandi
- SH Bigner
- SL Harris
- SR Romanov
- SW Coons
- T Buder
- T de Lange
- T Forshew
- T Kanda
- T Kuilman
- T Mazor
- T Ozawa
- T Watanabe
- TA Johannessen
- TD Halazonetis
- TM Bryan
- TM Bryan
- V Codd
- VC Gray-Schopfer
- VP Collins
- W Xu
- WA Flavahan
- WA Flavahan
- WC Hahn
- WE Wright
- WE Wright
- WH Liggett Jr
- WM Rozen
- X Hu
- X Lan
- Y Jiao
- YC Tang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Searches for Gravitational Waves from Known Pulsars at Two Harmonics in the Second and Third LIGO-Virgo Observing Runs
- Author
- Abbott R
- Abe H
- Acernese F
- Ackley K
- Adhikari N
- Adhikari RX
- Adkins VK
- Adya VB
- Affeldt C
- Agarwal D
- Agathos M
- Agatsuma K
- Aggarwal N
- Aguiar OD
- Aiello L
- Ain A
- Ajith P
- Akutsu T
- Albanesi S
- Alfaidi RA
- Allocca A
- Altin PA
- Amato A
- Anand C
- Anand S
- Ananyeva A
- Anderson SB
- Anderson WG
- Ando M
- Andrade T
- Andres N
- Andres-Carcasona M
- Andric T
- Angelova SV
- Ansoldi S
- Antelis JM
- Antier S
- Antonopoulou D
- Apostolatos T
- Appavuravther EZ
- Appert S
- Apple SK
- Arai K
- Araya A
- Araya MC
- Areeda JS
- Arellano FEP
- Arene M
- Aritomi N
- Arnaud N
- Arogeti M
- Aronson SM
- Arun KG
- Arzoumanian Z
- Asada H
- Asali Y
- Ashton G
- Aso Y
- Assiduo M
- Aston SM
- Astone P
- Aubin F
- AultONeal K
- Austin C
- Babak S
- Badaracco F
- Bader MKM
- Badger C
- Bae S
- Bae Y
- Baer AM
- Bagnasco S
- Bai Y
- Bailes M
- Baird J
- Bajpai R
- Baka T
- Ball M
- Ballardin G
- Ballmer SW
- Balsamo A
- Baltus G
- Banagiri S
- Banerjee B
- Bankar D
- Barayoga JC
- Barbieri C
- Barish BC
- Barker D
- Barneo P
- Barone F
- Barr B
- Barsotti L
- Barsuglia M
- Barta D
- Bartlett J
- Barton MA
- Bartos I
- Basak S
- Bassiri R
- Basti A
- Basu A
- Bawaj M
- Bayley JC
- Bazzan M
- Becher BR
- Becsy B
- Bedakihale VM
- Beirnaert F
- Bejger M
- Belahcene I
- Benedetto V
- Beniwal D
- Benjamin MG
- Bennett TF
- Bentley JD
- BenYaala M
- Bera S
- Berbel M
- Bergamin F
- Berger BK
- Bernuzzi S
- Bersanetti D
- Bertolini A
- Betzwieser J
- Beveridge D
- Bhandare R
- Bhandari AV
- Bhardwaj U
- Bhatt R
- Bhattacharjee D
- Bhaumik S
- Bianchi A
- Bilenko IA
- Billingsley G
- Bini S
- Birney R
- Birnholtz O
- Biscans S
- Bischi M
- Biscoveanu S
- Bisht A
- Biswas B
- Bitossi M
- Bizouard MA
- Blackburn JK
- Blair CD
- Blair DG
- Blair RM
- Bobba F
- Bode N
- Boer M
- Bogaert G
- Bogdanov S
- Boldrini M
- Bolingbroke GN
- Bonavena LD
- Bondu F
- Bonilla E
- Bonnand R
- Booker P
- Boom BA
- Bork R
- Boschi V
- Bose N
- Bose S
- Bossilkov V
- Boudart V
- Bouffanais Y
- Bozzi A
- Bradaschia C
- Brady PR
- Bramley A
- Branch A
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- Brau JE
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- Briggs JH
- Brillet A
- Brinkmann M
- Brockill P
- Brooks AF
- Brooks J
- Brown DD
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- Bruno G
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- Bulten HJ
- Buonanno A
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- Callaghan JD
- Callister TA
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- Cameron J
- Camp JB
- Canepa M
- Canevarolo S
- Cannavacciuolo M
- Cannon KC
- Cao H
- Cao Z
- Capocasa E
- Capote E
- Carapella G
- Carbognani F
- Carlassara M
- Carlin JB
- Carney MF
- Carpinelli M
- Carrillo G
- Carullo G
- Carver TL
- Casentini C
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- Caudill S
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- Cesarini E
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- Chiang CY
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- Wysocki DM
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- Yamamoto K
- Yamamoto T
- Yamashita K
- Yamazaki R
- Yang FW
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- Yang Y
- Yang Y
- Yang YC
- Yap MJ
- Yeeles DW
- Yeh SW
- Yelikar AB
- Ying M
- Yokoyama J
- Yokozawa T
- Yoo J
- Yoshioka T
- Yu H
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- Zanolin M
- Zeidler S
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- Zendri JP
- Zevin M
- Zhan M
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- Zhao Y
- Zhou R
- Zhou Z
- Zhu XJ
- Zhu ZH
- Zucker ME
- Zweizig J
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2022
- Field of study
We present a targeted search for continuous gravitational waves (GWs) from 236 pulsars using data from the third observing run of LIGO and Virgo (O3) combined with data from the second observing run (O2). Searches were for emission from the l = m = 2 mass quadrupole mode with a frequency at only twice the pulsar rotation frequency (single harmonic) and the l = 2, m = 1, 2 modes with a frequency of both once and twice the rotation frequency (dual harmonic). No evidence of GWs was found, so we present 95% credible upper limits on the strain amplitudes h (0) for the single-harmonic search along with limits on the pulsars' mass quadrupole moments Q (22) and ellipticities epsilon. Of the pulsars studied, 23 have strain amplitudes that are lower than the limits calculated from their electromagnetically measured spin-down rates. These pulsars include the millisecond pulsars J0437-4715 and J0711-6830, which have spin-down ratios of 0.87 and 0.57, respectively. For nine pulsars, their spin-down limits have been surpassed for the first time. For the Crab and Vela pulsars, our limits are factors of similar to 100 and similar to 20 more constraining than their spin-down limits, respectively. For the dual-harmonic searches, new limits are placed on the strain amplitudes C (21) and C (22). For 23 pulsars, we also present limits on the emission amplitude assuming dipole radiation as predicted by Brans-Dicke theory
Recommended from our members
Observation of Gravitational Waves from the Coalescence of a 2.5â4.5 M <sub>â</sub> Compact Object and a Neutron Star
- Author
- Abac AG
- Abbott R
- Abchouyeh M Aghaei
- Abouelfettouh I
- Acernese F
- Ackley K
- Adhicary S
- Adhikari N
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- Adkins VK
- Agarwal D
- Agathos M
- Aguiar OD
- Aguilar I
- Aiello L
- Ain A
- Ajith P
- Akutsu T
- Akçay S
- Al-Jodah A
- Al-Shammari S
- Albanesi S
- Alfaidi RA
- Allocca A
- Alléné C
- Altin PA
- Alvarez-Lopez S
- Amato A
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- Andrés-Carcasona M
- Anglin J
- Ansoldi S
- Antelis JM
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- Yamamoto TS
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- Yamazaki R
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- Yan T
- Yang F
- Yang FW
- Yang KZ
- Yang Y
- Yarbrough Z
- Yasui H
- Yeh S-W
- Yelikar AB
- Yin X
- Yokoyama J
- Yokozawa T
- Yoo J
- Yu H
- Yuan S
- Yuzurihara H
- ZadroĆŒny A
- Zanolin M
- Zeeshan M
- Zelenova T
- Zendri J-P
- Zeoli M
- Zerrad M
- Zevin M
- Zhang AC
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- Zhao Yuhang
- Zheng Y
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- Zhu Z-H
- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- The Astrophysical Journal Letters
- Publication date
- 26/07/2024
- Field of study
Abstract
We report the observation of a coalescing compact binary with component masses 2.5â4.5 M
â and 1.2â2.0 M
â (all measurements quoted at the 90% credible level). The gravitational-wave signal GW230529_181500 was observed during the fourth observing run of the LIGOâVirgoâKAGRA detector network on 2023 May 29 by the LIGO Livingston observatory. The primary component of the source has a mass less than 5 M
â at 99% credibility. We cannot definitively determine from gravitational-wave data alone whether either component of the source is a neutron star or a black hole. However, given existing estimates of the maximum neutron star mass, we find the most probable interpretation of the source to be the coalescence of a neutron star with a black hole that has a mass between the most massive neutron stars and the least massive black holes observed in the Galaxy. We provisionally estimate a merger rate density of
55
â
47
+
127
Gpc
â
3
yr
â
1
for compact binary coalescences with properties similar to the source of GW230529_181500; assuming that the source is a neutron starâblack hole merger, GW230529_181500-like sources may make up the majority of neutron starâblack hole coalescences. The discovery of this system implies an increase in the expected rate of neutron starâblack hole mergers with electromagnetic counterparts and provides further evidence for compact objects existing within the purported lower mass gap.</jats:p
Searches for gravitational waves from known pulsars at two harmonics in the second and third LIGO-Virgo observing runs
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- Zhu XJ
- Zhu Z-H
- Zucker ME
- Zweizig J
- Publication venue
- 'American Astronomical Society'
- Publication date
- 25/05/2022
- Field of study
We present a targeted search for continuous gravitational waves (GWs) from 236 pulsars using data from the third observing run of LIGO and Virgo (O3) combined with data from the second observing run (O2). Searches were for emission from the l = m = 2 mass quadrupole mode with a frequency at only twice the pulsar rotation frequency (single harmonic) and the l = 2, m = 1, 2 modes with a frequency of both once and twice the rotation frequency (dual harmonic). No evidence of GWs was found, so we present 95% credible upper limits on the strain amplitudes h0 for the single-harmonic search along with limits on the pulsars' mass quadrupole moments Q22 and ellipticities Δ. Of the pulsars studied, 23 have strain amplitudes that are lower than the limits calculated from their electromagnetically measured spin-down rates. These pulsars include the millisecond pulsars J0437â4715 and J0711â6830, which have spin-down ratios of 0.87 and 0.57, respectively. For nine pulsars, their spin-down limits have been surpassed for the first time. For the Crab and Vela pulsars, our limits are factors of âŒ100 and âŒ20 more constraining than their spin-down limits, respectively. For the dual-harmonic searches, new limits are placed on the strain amplitudes C21 and C22. For 23 pulsars, we also present limits on the emission amplitude assuming dipole radiation as predicted by Brans-Dicke theory