Microstrip Coupled Band Pass Filter using Parallel Coupled Lines used for EMI Reduction

The use of BPF is in telecommunications wireless systems. The signal to be transmitted and which they are received are filtered at a center frequency having some significant bandwidth. This paper comprises a brief knowledge related to designing of a band pass filter (BPF) using microstrip parallel coupled line structure for reduction of noise and EMI. The band pass filter has a center frequency of 2.45GHz having less insertion loss and more than 20dB return loss in its pass band having more than 5% moderate bandwidth is successfully designed.The center frequency is selected such that it is mainly used in WLAN network or high speed wireless broadband is configured to transmit data voice and video IP because system requires more bandwidth. The layout is designed such that centre frequency is 2.45GHz with a fractional bandwidth of 200MHz and impedance resonator length of each coupled line is seperated such that impedance is adjusted to 50Ω exactly.Two sections are mainly given in design: two coupled lines distinguished by a non-uniform line resonator.The impedance resonators gives a separate resonance to obtain the passband region or response.The simulation is perform out on a HFSS software

Resolvins suppress tumor growth and enhance cancer therapy

National Cancer Institute grants RO1 01CA170549-02 (to D. Panigrahy and C.N. Serhan), ROCA148633-01A4 (to D. Panigrahy), and GM095467 (to C.N. Serhan); the Stop and Shop Pediatric Brain Tumor Fund (to M.W. Kieran); the CJ Buckley Pediatric Brain Tumor Fund (to M.W. Kieran); Alex Lemonade Stand (to M.W. Kieran); Molly’s Magic Wand for Pediatric Brain Tumors (to M.W. Kieran); the Markoff Foundation Art-In-Giving Foundation (to M.W. Kieran); the Kamen Foundation (to M.W. Kieran); Jared Branfman Sunflowers for Life (to M.W.K.); and The Wellcome Trust program 086867/Z/08 (to M. Perretti)

To Enhance the Properties of Gepolymer Concrete for Different Molarities of NaOH and Varying Ratio of Na2SiO3/ NaOH

The development of fly ash based geopolymer concrete,  need of a ‘green' concrete in order to reduce the carbon dioxide emission from the cement production. Portland cement is one of the most energy intensive construction materials. Every ton of Portland cement releases a ton of carbon dioxide into the atmosphere. On the other side fly ash is waste material available from thermal power plant.  Fly ash is possible up to certain extent to reduce the cementing material due to pozzolanic activity of fly ash. Therefore it is necessary to activate the fly ash by using alkaline activators. In present study investigations sodium based activators are used. Sodium hydroxide solution having different molarities  concentration are used and Sodium silicate solution with Na2O  and SiO2  were maintained constant throughout the experimentation. Alkaline solutions might be sodium based or potassium based. Generally sodium based solution is used from economy and availability point of view.The experimental paper presents the cube test results of geopolymer concrete with different molarities of sodium hydroxide with various ratio of sodium silicate solution. The adopted mix design  of M30 grade  of geopolymer concrete procedure is relevant to previously adopted experimental study adopted by S.V.Patankar et.al(2013) carried the research of binder ratio in the production of fly ash based geopolymer concrete. This existing cement concrete Mix Design was applied to Geopolymer Concrete as experimental study to identify the  higher compressive strength of concrete cubes with different molarities of sodium hydroxide

A Comprehensive Review Of Drug-Device Combination

<p>The trend of combining drugs and devices has brought about advancements in medical product development, regulatory approval, and business involvement. These combination products are designed with modern links between key technologies and complementary elements, while still maintaining their fundamental purpose. To better understand the benefits and drawbacks of these combination medications, we will look at case studies of drug-device stents and transdermal patches. It seems that this generation of combination products has created a new, high-value area, as evidenced by advancements in product control and the realization that the competitive advantage lies in the sophistication of the mix. Recent studies show that combining technology, medicine, and biologics creates a developing opportunity. According to our analysis, a new type of combination product's first product includes both the regulator and the sponsor. If this first product is granted a license, it can greatly reduce uncertainty around the entire class of combination medications, establishing a leading regulatory center. The sponsor of a new type of combination product is crucial in reducing uncertainty by helping decision-makers understand the fundamental objective of the combination product.</p&gt

Plastic CD34 and CD38 expression in adult B-cell precursor acute lymphoblastic leukemia explains ambiguity of leukemia-initiating stem cell populations

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is an aggressive hematologic malignancy of bone-marrow (BM)-derived lymphoid precursor cells at various stages of differentiation. Although first-line therapy with chemotherapy and—in the case of BCR-ABL1 positive ALL—tyrosine kinase inhibitors is initially highly effective with remission rates of >90%, the overall survival rate in adult patients is 40–50% across all risk groups. Relapse originates from putative leukemia-initiating cells (LICs) that are intrinsically resistant to chemotherapeutic regimens, which may explain the poor long-term prognosis of patients with disease recurrence. Eradication of LICs thus is a principal aim of novel therapeutic approaches. A prerequisite for developing effective LIC-targeted treatments is the ability to identify and clinically monitor LICs in ALL, a goal that has to date been elusive. The existence, phenotype, biological properties and the hierarchical organization of LICs in BCP-ALL remain highly controversial. ..