Multi-wavelength characterisation of z~2 clustered, dusty star forming galaxies discovered by Planck

(abridged) We report the discovery of PHz G95.5-61.6, a complex structure detected in emission in the Planck all-sky survey that corresponds to two over-densities of high-redshift galaxies. This is the first source from the Planck catalogue of high-z candidates that has been completely characterised with follow-up observations from the optical to the sub-millimetre domain. Herschel/SPIRE observations at 250, 350 and 500 microns reveal the existence of five sources producing a 500 microns emission excess that spatially corresponds to the candidate proto-clusters discovered by Planck. Further observations at CFHT in the optical bands (g and i) and in the near infrared (J, H and K_s), plus mid infrared observations with IRAC/Spitzer (at 3.6 and 4.5 microns) confirm that the sub-mm red excess is associated with an over-density of colour-selected galaxies. Follow-up spectroscopy of 13 galaxies with VLT/X-Shooter establishes the existence of two high-z structures: one at z~1.7 (three confirmed member galaxies), the other at z~2.0 (six confirmed members). This double structure is also seen in the photometric redshift analysis of a sample of 127 galaxies located inside a circular region of 1'-radius containing the five Herschel/SPIRE sources, where we found a double-peaked excess of galaxies at z~1.7 and z~2.0 with respect to the surrounding region. These results suggest that PHz G95.5-61.6 corresponds to two accreting nodes, not physically linked to one another, embedded in the large scale structure of the Universe at z~2 and along the same line-of-sight. In conclusion, the data, methods and results illustrated in this pilot project confirm that Planck data can be used to detect the emission from clustered, dusty star forming galaxies at high-z, and, thus, to pierce through the early growth of cluster-scale structures.Comment: 15 pages, 13 figures. Accepted for publication in Astronomy and Astrophysic

Finite-temperature simulations of the scissors mode in Bose-Einstein condensed gases

The dynamics of a trapped Bose-condensed gas at finite temperatures is described by a generalized Gross-Pitaevskii equation for the condensate order parameter and a semi-classical kinetic equation for the thermal cloud, solved using $N$-body simulations. The two components are coupled by mean fields as well as collisional processes that transfer atoms between the two. We use this scheme to investigate scissors modes in anisotropic traps as a function of temperature. Frequency shifts and damping rates of the condensate mode are extracted, and are found to be in good agreement with recent experiments.Comment: 4 pages, 3 figure

Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice.

Gut dysbiosis due to the adverse effects of antibiotics affects outcomes of lung infection. Previous murine models relied on significant depletion of both gut and lung microbiota, rendering the analysis of immune gut-lung cross-talk difficult. Here, we study the effects of antibiotic-induced gut dysbiosis without lung dysbiosis on lung immunity and the consequences on acute P. aeruginosa lung infection. C57BL6 mice received 7 days oral vancomycin-colistin, followed by normal regimen or fecal microbial transplant or Fms-related tyrosine kinase 3 ligand (Flt3-Ligand) over 2 days, and then intra-nasal P. aeruginosa strain PAO1. Gut and lung microbiota were studied by next-generation sequencing, and lung infection outcomes were studied at 24 h. Effects of vancomycin-colistin on underlying immunity and bone marrow progenitors were studied in uninfected mice by flow cytometry in the lung, spleen, and bone marrow. Vancomycin-colistin administration induces widespread cellular immunosuppression in both the lung and spleen, decreases circulating hematopoietic cytokine Flt3-Ligand, and depresses dendritic cell bone marrow progenitors leading to worsening of P. aeruginosa lung infection outcomes (bacterial loads, lung injury, and survival). Reversal of these effects by fecal microbial transplant shows that these alterations are related to gut dysbiosis. Recombinant Flt3-Ligand reverses the effects of antibiotics on subsequent lung infection. These results show that gut dysbiosis strongly impairs monocyte/dendritic progenitors and lung immunity, worsening outcomes of P. aeruginosa lung infection. Treatment with a fecal microbial transplant or immune stimulation by Flt3-Ligand both restore lung cellular responses to and outcomes of P. aeruginosa following antibiotic-induced gut dysbiosis

Dissipative dynamics of vortex arrays in trapped Bose-condensed gases: neutron stars physics on μ\muK scale

We develop a theory of dissipative dynamics of large vortex arrays in trapped Bose-condensed gases. We show that in a static trap the interaction of the vortex array with thermal excitations leads to a non-exponential decay of the vortex structure, and the characteristic lifetime depends on the initial density of vortices. Drawing an analogy with physics of pulsar glitches, we propose an experiment which employs the heating of the thermal cloud in the course of the decay of the vortex array as a tool for a non-destructive study of the vortex dynamics.Comment: 4 pages, revtex; revised versio

Quorum-sensing activity and related virulence factor expression in clinically pathogenic isolates of Pseudomonas aeruginosa

AbstractRespiratory isolates of Pseudomonas aeruginosa were collected from 58 critically-ill patients with ventilator-associated pneumonia. Expression of elastase and pyocyanin was assessed semi-quantitatively, while quorum-sensing activity was assessed by quantifying the levels of the autoinducers N-3-oxododecanoyl-L-homoserine lactone (C12-HSL) and N-butanoyl-L-homoserine lactone (C4-HSL). Correlations were sought between quorum-sensing activity and the expression of these two virulence factors, and all results were compared to those obtained with the laboratory reference strains PA103, a strain defective in quorum-sensing, and PAO1, a functional quorum-sensing strain. More than two-thirds of clinically pathogenic isolates had increased levels of elastase and/or pyocyanin, and high quorum-sensing activity, as assessed by autoinducer levels. However, a strong correlation between quorum-sensing activity and virulence factor production was revealed only for elastase and not for pyocyanin (C12-HSL/elastase, r = 0.7, p 2 × 10−9; C4-HSL/elastase, r = 0.7, p 2 × 10−9). These data suggest that the pathogenicity of P. aeruginosa isolates from critically-ill patients with ventilator-associated pneumonia is caused, at least in part, by an increase in elastase production regulated by quorum-sensing, while increased pyocyanin production in these isolates may be regulated predominantly by mechanisms other than quorum-sensing

Oscillations of rotating trapped Bose-Einstein condensates

The tensor-virial method is applied for a study of oscillation modes of uniformly rotating Bose-Einstein condensed gases, whose rigid body rotation is supported by an vortex array. The second order virial equations are derived in the hydrodynamic regime for an arbitrary external harmonic trapping potential assuming that the condensate is a superfluid at zero temperature. The axisymmetric equilibrium shape of the condensate is determined as a function of the deformation of the trap; its domain of stability is bounded by the constraint $\Omega<1$ on the rotation rate (measured in units of the trap frequency $\omega_0$.) The oscillations of the axisymmetric condensate are stable with respect to the transverse-shear, toroidal and quasi-radial modes of oscillations, corresponding to the $l= 2$, $| m| = 0,1,2$ surface deformations. In non-axisymmetric traps, the equilibrium constrains the (dimensionless) deformation in the plane orthogonal to the rotation to the domain $A_2 > \Omega^2$ with $\Omega< 1$. The second harmonic oscillation modes in non-axisymmetric traps separate into two classes which have even or odd parity with respect to the direction of the rotation axis. Numerical solutions show that these modes are stable in the parameter domain where equilibrium figures exist.Comment: 16 pages, including 4 figures, uses Revtex; v2 includes a treatment of modes in unisotropic traps; PRA in pres

Planck's Dusty GEMS: Gravitationally lensed high-redshift galaxies discovered with the Planck survey

We present an analysis of 11 bright far-IR/submm sources discovered through a combination of the Planck survey and follow-up Herschel-SPIRE imaging. Each source has a redshift z=2.2-3.6 obtained through a blind redshift search with EMIR at the IRAM 30-m telescope. Interferometry obtained at IRAM and the SMA, and optical/near-infrared imaging obtained at the CFHT and the VLT reveal morphologies consistent with strongly gravitationally lensed sources. Additional photometry was obtained with JCMT/SCUBA-2 and IRAM/GISMO at 850 um and 2 mm, respectively. All objects are bright, isolated point sources in the 18 arcsec beam of SPIRE at 250 um, with spectral energy distributions peaking either near the 350 um or the 500 um bands of SPIRE, and with apparent far-infrared luminosities of up to 3x10^14 L_sun. Their morphologies and sizes, CO line widths and luminosities, dust temperatures, and far-infrared luminosities provide additional empirical evidence that these are strongly gravitationally lensed high-redshift galaxies. We discuss their dust masses and temperatures, and use additional WISE 22-um photometry and template fitting to rule out a significant contribution of AGN heating to the total infrared luminosity. Six sources are detected in FIRST at 1.4 GHz. Four have flux densities brighter than expected from the local far-infrared-radio correlation, but in the range previously found for high-z submm galaxies, one has a deficit of FIR emission, and 6 are consistent with the local correlation. The global dust-to-gas ratios and star-formation efficiencies of our sources are predominantly in the range expected from massive, metal-rich, intense, high-redshift starbursts. An extensive multi-wavelength follow-up programme is being carried out to further characterize these sources and the intense star-formation within them.Comment: A&A accepte

Pinning of quantized vortices in helium drop by dopant atoms and molecules

Using a density functional method, we investigate the properties of liquid 4He droplets doped with atoms (Ne and Xe) and molecules (SF_6 and HCN). We consider the case of droplets having a quantized vortex pinned to the dopant. A liquid drop formula is proposed that accurately describes the total energy of the complex and allows one to extrapolate the density functional results to large N. For a given impurity, we find that the formation of a dopant+vortex+4He_N complex is energetically favored below a critical size N_cr. Our result support the possibility to observe quantized vortices in helium droplets by means of spectroscopic techniques.Comment: Typeset using Revtex, 3 pages and 5 figures (4 Postscript, 1 jpeg

Long-Term Consequences of COVID-19: A 1-Year Analysis.

Long-lasting symptoms after SARS-CoV-2 infection have been described many times in the literature and are referred to as Long COVID. In this prospective, longitudinal, monocentric, observational study, we collected the health complaints of 474 patients (252 ambulatory and 222 hospitalized) at Lausanne University Hospital 1 year after COVID-19 diagnosis. Using a self-reported health survey, we explored cardiopulmonary, vascular, neurological, and psychological complaints. Our results show that age, Charlson comorbidity index, and smoking habits were associated with hospital admission. Regarding the vascular system, we found that having had thromboembolism before SARS-CoV-2 infection was significantly associated with a higher risk of recurrence of thromboembolism at 1 year. In the neurologic evaluation, the most frequent symptom was fatigue, which was observed in 87.5% of patients, followed by "feeling slowed down", headache, and smell disturbance in 71.5%, 68.5%, and 60.7% of cases, respectively. Finally, our cohort subjects scored higher overall in the STAI, CESD, Maastricht, and PSQI scores (which measure anxiety, depression, fatigue, and sleep, respectively) than the healthy population. Using cluster analysis, we identified two phenotypes of patients prone to developing Long COVID. At baseline, CCS score, prior chronic disease, stroke, and atrial fibrillation were associated with Long COVID. During COVID infection, mechanical ventilation and five neurological complaints were also associated with Long COVID. In conclusion, this study confirms the wide range of symptoms developed after COVID with the involvement of all the major systems. Early identification of risk factors associated with the development of Long COVID could improve patient follow-up; nevertheless, the low specificity of these factors remains a challenge to building a systematic approach

Precision Feshbach spectroscopy of ultracold Cs-2

We have observed and located more than 60 magnetic field-induced Feshbach resonances in ultracold collisions of ground-state Cs-133 atoms. Multiple extremely weak Feshbach resonances associated with g-wave molecular states are detected through variations in the radiative collision cross sections. The Feshbach spectroscopy allows us to determine the interactions between ultracold cesium atoms and the molecular energy structure near the dissociation continuum with unprecedented precision. Our work not only represents a very successful collaboration of experimental and theoretical efforts, but also provides essential information for cesium Bose-Einstein condensation, Cs-2 molecules, and atomic clock experiments