23 research outputs found
Survival and Flight Characteristics of Captive-Reared and Wild Northern Bobwhites in Texas
Introductions of captive-reared northern bobwhite (Colinus virginianus) to bolster native populations have been largely unsuccessful. We compared the survival and flight characteristics of game-farm (n 46), first-generation (F1) (n = 48), wild translocated (n = 45), and wild native (n = 50) northern bobwhites. In November 1993, all birds were radio-collared, leg banded, sexed, and aged. Birds were then released on a study area in Brooks County, Texas in groups of about 15, 1 bird at a time. Upon release, the direction of departure, speed, and time required to reach cover were recorded. The mean flight speed and distance flown for wild bobwhites was significantly greater (P \u3c 0.01) than captive-reared bobwhites. Wild native, wild translocated, and F1 groups were non-randomly distributed in direction of departure at release site (P \u3c 0.01). Survival of wild groups was significantly higher than captive-raised groups (P \u3c 0.05). The major cause of mortality in all groups was mammalian depredation. Fifteen F1 quail and 1 game-farm quail integrated into wild coveys. Our results re-confirm the inability of game-farm and first-generation northern bobwhites to survive in the wild, and we offer flight speed as one potential causal factor
Survival and Home Range Estimates of Pen-Raised Northern Bobwhites in Buffer Strip and Non-Buffer Strip Habitats
We investigated the effect of agricultural buffer strips on survival and home range estimates of pen-raised northern bobwhites (Colinus virginianus) at Tudor Farms on the Eastern Shore of Maryland. In September 2000 we released groups of bobwhites into 9 buffer strip (treatment) areas and 9 non-buffer strip (control) areas among 11 agricultural farms. Each group consisted of 4 radiomarked bobwhites and 26 non-radiomarked bobwhites. To maintain contact with the established coveys, additional radiomarked bobwhites (n = 177) were introduced into the coveys as radiomarked birds died. Survival for bobwhites released in buffer strip areas was lower (P \u3c 0.001) than survival in non-buffer strip areas. None of the radiomarked bobwhites released in the buffer strip areas survived past 27 weeks, whereas 11% of radiomarked bobwhites in non-buffer strip areas survived to 27 weeks and 1 bird survived to 41 weeks. Predation was the primary mortality factor (88%), followed by unknown causes (7%), stress (2%), hunting (2%), and road kill (1%). Mean fall and winter home range (95% minimum convex polygon) for 21 bobwhite coveys was 24.2 +- 3.5 ha, ranging from 1.7 to 65.8 ha. Home range areas of bobwhite coveys in buffer strips (n = 12, x¯ +- 15.0 2.7 ha) was significantly smaller (P = 0.002) than non-buffer strip coveys (n = 9, x¯ = 36.4 +- 4.9 ha). We conclude that the smaller home ranges in buffer strip areas seem to indicate better habitat quality; however, high mortality rates of pen-raised bobwhites limited our ability to confirm this
Examining sustainability in a hospital setting: Case of smoking cessation
<p>Abstract</p> <p>Background</p> <p>The Ottawa Model of Smoking Cessation (OMSC) is a hospital-based smoking cessation program that is expanding across Canada. While the short-term effectiveness of hospital cessation programs has been documented, less is known about long-term sustainability. The purpose of this exploratory study was to understand how hospitals using the OMSC were addressing sustainability and determine if there were critical factors or issues that should be addressed as the program expanded.</p> <p>Methods</p> <p>Six hospitals that differed on OMSC program activities (identify and document smokers, advise quitting, provide medication, and offer follow-up) were intentionally selected, and two key informants per hospital were interviewed using a semi-structured interview guide. Key informants were asked to reflect on the initial decision to implement the OMSC, the current implementation process, and perceived sustainability of the program. Qualitative analysis of the interview transcripts was conducted and themes related to problem definition, stakeholder influence, and program features emerged.</p> <p>Results</p> <p>Sustainability was operationalized as higher performance of OMSC activities than at baseline. Factors identified in the literature as important for sustainability, such as program design, differences in implementation, organizational characteristics, and the community environment did not explain differences in program sustainability. Instead, key informants identified factors that reflected the interaction between how the health problem was defined by stakeholders, how priorities and concerns were addressed, features of the program itself, and fit within the hospital context and resources as being influential to the sustainability of the program.</p> <p>Conclusions</p> <p>Applying a sustainability model to a hospital smoking cessation program allowed for an examination of how decisions made during implementation may impact sustainability. Examining these factors during implementation may provide insight into issues affecting program sustainability, and foster development of a sustainability plan. Based on this study, we suggest that sustainability plans should focus on enhancing interactions between the health problem, program features, and stakeholder influence.</p
Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people
The use of spoken and written language is a fundamental human capacity. Individual differences in reading- and language-related skills are influenced by genetic variation, with twin-based heritability estimates of 30 to 80% depending on the trait. The genetic architecture is complex, heterogeneous, and multifactorial, but investigations of contributions of single-nucleotide polymorphisms (SNPs) were thus far underpowered. We present a multicohort genome-wide association study (GWAS) of five traits assessed individually using psychometric measures (word reading, nonword reading, spelling, phoneme awareness, and nonword repetition) in samples of 13,633 to 33,959 participants aged 5 to 26 y. We identified genome-wide significant association with word reading (rs11208009, P = 1.098 x 10(-8)) at a locus that has not been associated with intelligence or educational attainment. All five reading-/language-related traits showed robust SNP heritability, accounting for 13 to 26% of trait variability. Genomic structural equation modeling revealed a shared genetic factor explaining most of the variation in word/nonword reading, spelling, and phoneme awareness, which only partially overlapped with genetic variation contributing to nonword repetition, intelligence, and educational attainment. A multivariate GWAS of word/nonword reading, spelling, and phoneme awareness maximized power for follow-up investigation. Genetic correlation analysis with neuroimaging traits identified an association with the surface area of the banks of the left superior temporal sulcus, a brain region linked to the processing of spoken and written language. Heritability was enriched for genomic elements regulating gene expression in the fetal brain and in chromosomal regions that are depleted of Neanderthal variants. Together, these results provide avenues for deciphering the biological underpinnings of uniquely human traits.Peer reviewe
Hypothesis-driven genome-wide association studies provide novel insights into genetics of reading disabilities
Peer reviewe
Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people
The use of spoken and written language is a fundamental human capacity. Individual differences in reading- and language-related skills are influenced by genetic variation, with twin-based heritability estimates of 30-80%, depending on the trait. The genetic architecture is complex, heterogeneous, and multifactorial, but investigations of contributions of single-nucleotide polymorphisms (SNPs) were thus far underpowered. We present a multicohort genome-wide association study (GWAS) of five traits assessed individually using psychometric measures: word reading, nonword reading, spelling, phoneme awareness, and nonword repetition, in samples of 13,633 to 33,959 participants aged 5-26 years. We identified genome-wide significant association with word reading (rs11208009, p=1.098 x 10-8) at a locus that has not been associated with intelligence or educational attainment. All five reading-/language-related traits showed robust SNP-heritability, accounting for 13-26% of trait variability. Genomic structural equation modelling revealed a shared genetic factor explaining most variation in word/nonword reading, spelling, and phoneme awareness, which only partially overlapped with genetic variation contributing to nonword repetition, intelligence and educational attainment. A multivariate GWAS of word/nonword reading, spelling, and phoneme awareness maximized power for follow-up investigation. Genetic correlation analysis of multivariate GWAS results with neuroimaging traits identified association with the surface area of the banks of the left superior temporal sulcus, a brain region linked to processing of spoken and written language. Heritability was enriched for genomic elements regulating gene expression in the fetal brain, and in chromosomal regions that are depleted of Neanderthal variants. Together, these results provide new avenues for deciphering the biological underpinnings of uniquely human traits