135 research outputs found
A Rapid Gamma-Ray Glow Flux Reduction Observed From 20 km Altitude
Two gamma-ray glows were observed by a high-altitude NASA ER-2 aircraft flying at 20 km altitude over a thunderstorm in Colorado, USA. The flux of the first glow rapidly intensified and then abruptly decreased within a few tens of milliseconds. On a timescale of seconds, the flux decrease occurred simultaneously with a hybrid intra-cloud/cloud-to-ground lightning discharge beneath the aircraft. However, a more detailed analysis of the discharge dynamics indicated that the discharge activity was unusually calm during the actual period of the flux decrease. The lightning was observed with on-board antennas, optical sensor, and ground-based lightning mapping and location networks. Its closest activity was 12 km away from the aircraft, below and slightly ahead the course. The gamma-ray flux reduction happened roughly in the middle of the lightning development process. The glow spectral analysis for the periods of a weak and strong flux enhancement has been done. The spectra were found to be background-like and similar to each other.publishedVersio
States and transitions in black-hole binaries
With the availability of the large database of black-hole transients from the
Rossi X-Ray Timing Explorer, the observed phenomenology has become very
complex. The original classification of the properties of these systems in a
series of static states sorted by mass accretion rate proved not to be able to
encompass the new picture. I outline here a summary of the current situation
and show that a coherent picture emerges when simple properties such as X-ray
spectral hardness and fractional variability are considered. In particular,
fast transition in the properties of the fast time variability appear to be
crucial to describe the evolution of black-hole transients. Based on this
picture, I present a state-classification which takes into account the observed
transitions. I show that, in addition to transients systems, other black-hole
binaries and Active Galactic Nuclei can be interpreted within this framework.
The association between these states and the physics of the accretion flow
around black holes will be possible only through modeling of the full time
evolution of galactic transient systems.Comment: 30 pages, 11 figures, To appear in Belloni, T. (ed.): The Jet
Paradigm - From Microquasars to Quasars, Lect. Notes Phys. 794 (2009
Fast variability from black-hole binaries
Currently available information on fast variability of the X-ray emission
from accreting collapsed objects constitutes a complex phenomenology which is
difficult to interpret. We review the current observational standpoint for
black-hole binaries and survey models that have been proposed to interpret it.
Despite the complex structure of the accretion flow, key observational
diagnostics have been identified which can provide direct access to the
dynamics of matter motions in the close vicinity of black holes and thus to the
some of fundamental properties of curved spacetimes, where strong-field general
relativistic effects can be observed.Comment: 20 pages, 11 figures. Accepted for publication in Space Science
Reviews. Also to appear in hard cover in the Space Sciences Series of ISSI
"The Physics of Accretion onto Black Holes" (Springer Publisher
Accretion and ejection in black-hole X-ray transients
Aims: We summarize the current observational picture of the outbursts of
black-hole X-ray transients (BHTs), based on the evolution traced in a
hardness-luminosity diagram (HLD), and we offer a physical interpretation.
Methods: The basic ingredient in our interpretation is the Poynting-Robertson
Cosmic Battery (PRCB, Contopoulos & Kazanas 1998), which provides locally the
poloidal magnetic field needed for the ejection of the jet. In addition, we
make two assumptions, easily justifiable. The first is that the mass-accretion
rate to the black hole in a BHT outburst has a generic bell-shaped form. This
is guaranteed by the observational fact that all BHTs start their outburst and
end it at the quiescent state. The second assumption is that at low accretion
rates the accretion flow is geometrically thick, ADAF-like, while at high
accretion rates it is geometrically thin.
Results: Both, at the beginning and the end of an outburst, the PRCB
establishes a strong poloidal magnetic field in the ADAF-like part of the
accretion flow, and this explains naturally why a jet is always present in the
right part of the HLD. In the left part of the HLD, the accretion flow is in
the form of a thin disk, and such a disk cannot sustain a strong poloidal
magnetic filed. Thus, no jet is expected in this part of the HLD. The
counterclockwise traversal of the HLD is explained as follows: the poloidal
magnetic field in the ADAF forces the flow to remain ADAF and the source to
move upwards in the HLD rather than to turn left. Thus, the history of the
system determines the counterclockwise traversal of the HLD. As a result, no
BHT is expected to ever traverse the entire HLD curve in the clockwise
direction.
Conclusions: We offer a physical interpretation of accretion and ejection in
BHTs with only one parameter, the mass transfer rate.Comment: Accepted for publication in A&
Modelling spectral and timing properties of accreting black holes: the hybrid hot flow paradigm
The general picture that emerged by the end of 1990s from a large set of
optical and X-ray, spectral and timing data was that the X-rays are produced in
the innermost hot part of the accretion flow, while the optical/infrared (OIR)
emission is mainly produced by the irradiated outer thin accretion disc. Recent
multiwavelength observations of Galactic black hole transients show that the
situation is not so simple. Fast variability in the OIR band, OIR excesses
above the thermal emission and a complicated interplay between the X-ray and
the OIR light curves imply that the OIR emitting region is much more compact.
One of the popular hypotheses is that the jet contributes to the OIR emission
and even is responsible for the bulk of the X-rays. However, this scenario is
largely ad hoc and is in contradiction with many previously established facts.
Alternatively, the hot accretion flow, known to be consistent with the X-ray
spectral and timing data, is also a viable candidate to produce the OIR
radiation. The hot-flow scenario naturally explains the power-law like OIR
spectra, fast OIR variability and its complex relation to the X-rays if the hot
flow contains non-thermal electrons (even in energetically negligible
quantities), which are required by the presence of the MeV tail in Cyg X-1. The
presence of non-thermal electrons also lowers the equilibrium electron
temperature in the hot flow model to <100 keV, making it more consistent with
observations. Here we argue that any viable model should simultaneously explain
a large set of spectral and timing data and show that the hybrid
(thermal/non-thermal) hot flow model satisfies most of the constraints.Comment: 26 pages, 13 figures. To be published in the Space Science Reviews
and as hard cover in the Space Sciences Series of ISSI - The Physics of
Accretion on to Black Holes (Springer Publisher
Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample
Interpretation of genetic association results is difficult because signals often lack biological context. To generate hypotheses of the functional genetic etiology of complex cardiometabolic traits, we estimated the genetically determined component of gene expression from common variants using PrediXcan (1) and determined genes with differential predicted expression by trait. PrediXcan imputes tissue-specific expression levels from genetic variation using variant-level effect on gene expression in transcriptome data. To explore the value of imputed genetically regulated gene expression (GReX) models across different ancestral populations, we evaluated imputed expression levels for predictive accuracy genome-wide in RNA sequence data in samples drawn from European-Ancestry and African-Ancestry populations and identified substantial predictive power using European-derived models in a non-European target population.We then tested the association of GReX on 15 cardiometabolic traits including blood lipid levels, body mass index, height, blood pressure, fasting glucose and insulin, RR interval, fibrinogen level, factor VII level and white blood cell and platelet counts in 15 755 individuals across three ancestry groups, resulting in 20 novel gene-phenotype associations reaching experiment-wide significance across ancestries. In addition, we identified 18 significant novel gene-phenotype associations in our ancestry-specific analyses. Top associations were assessed for additional support via query of S-PrediXcan (2) results derived from publicly available genome-wide association studies summary data. Collectively, these findings illustrate the utility of transcriptome-based imputation models for discovery of cardiometabolic effect genes in a diverse dataset
Control of Transonic Cavity Flow Instability by Streamwise Air Injection
A time-dependent numerical model of a turbulent
Mach 1.5 flow over a rectangular cavity has been developed,
to investigate suppression strategies for its
natural self-sustained instability. This instability adversely
affects the cavity form drag, it produces large-amplitude
pressure oscillations in the enclosure and it
is a source of far-field acoustic radiation.
To suppress the natural flow instability, the leading
edge of the two-dimensional cavity model is fitted with
a simulated air jet that discharges in the downstream
direction. The jet mass flow rate and nozzle depth are
adjusted to attenuate the instability while minimising
the control mass flow rate.
The numerical predictions indicate that, at the selected
inflow conditions, the configurations with the
deepest nozzle (0.75 of the cavity depth) give the most
attenuation of the modelled instability, which is dominated
by the cavity second mode. The jet affects both
the unsteady pressure field and the vorticity distribution
inside the enclosure, which are, together, key
determinants of the cavity leading instability mode
amplitude. The unsteadiness of the pressure field is reduced
by the lifting of the cavity shear layer at the rear
end above the trailing edge. This disrupts the formation
of upstream travelling feed-back pressure waves
and the generation of far-field noise. The deep nozzle
also promotes a downstream bulk flow in the enclosure,
running from the upstream vertical wall to the
downstream one. This flow attenuates the large-scale
clockwise recirculation that is present in the unsuppressed
cavity flow. The same flow alters the top shear
layer vorticity thickness and probably affects the convective
growth of the shear layer cavity second mode
The On-orbit Calibrations for the Fermi Large Area Telescope
The Large Area Telescope (LAT) on--board the Fermi Gamma ray Space Telescope
began its on--orbit operations on June 23, 2008. Calibrations, defined in a
generic sense, correspond to synchronization of trigger signals, optimization
of delays for latching data, determination of detector thresholds, gains and
responses, evaluation of the perimeter of the South Atlantic Anomaly (SAA),
measurements of live time, of absolute time, and internal and spacecraft
boresight alignments. Here we describe on orbit calibration results obtained
using known astrophysical sources, galactic cosmic rays, and charge injection
into the front-end electronics of each detector. Instrument response functions
will be described in a separate publication. This paper demonstrates the
stability of calibrations and describes minor changes observed since launch.
These results have been used to calibrate the LAT datasets to be publicly
released in August 2009.Comment: 60 pages, 34 figures, submitted to Astroparticle Physic
Flowcharts for the management of biliary tract and ampullary carcinomas
No strategies for the diagnosis and treatment of biliary tract carcinoma have been clearly described. We developed flowcharts for the diagnosis and treatment of biliary tract carcinoma on the basis of the best clinical evidence. Risk factors for bile duct carcinoma are a dilated type of pancreaticobiliary maljunction (PBM) and primary sclerosing cholangitis. A nondilated type of PBM is a risk factor for gallbladder carcinoma. Symptoms that may indicate biliary tract carcinoma are jaundice and pain in the upper right area of the abdomen. The first step of diagnosis is to carry out blood biochemistry tests and ultrasonography (US) of the abdomen. The second step of diagnosis is to find the local extension of the carcinoma by means of computed tomography (CT), magnetic resonance imaging (MRI), magnetic resonance cholangiopancreatography (MRCP), percutaneous transhepatic cholangiography (PTC), and endoscopic retrograde cholangiopancreatography (ERCP). Because resection is the only way to completely cure biliary tract carcinoma, the indications for resection are determined first. In patients with resectable disease, the indications for biliary drainage or portal vein embolization (PVE) are checked. In those with nonresectable disease, biliary stenting, chemotherapy, radiotherapy, and/or best supportive care is selected
POD Analysis of Cavity Flow Instability
A Mach 1.5 turbulent cavity flow develops large-amplitude
oscillations, pressure drag and noise. This
type of flow instability affects practical engineering applications,
such as aircraft store bays. A simple model
of the flow instability is sought towards developing a
real-time model-based active control system for simple
geometries, representative of open aircraft store bays.
An explicit time marching second-order accurate
finite-volume scheme has been used to generate time-dependent
benchmark cavity flow data. Then, a simpler
and leaner numerical predictor for the unsteady
cavity pressure was developed, based on a Proper Orthogonal
Decomposition of the benchmark data.
The low order predictor gives pressure oscillations
in good agreement with the benchmark CFD method.
This result highlights the importance of large-scale
phase-coherent structures in the Mach 1.5 turbulent
cavity flow. At the selected test conditions, the significant
pressure ‘energy’ content of these structures
enabled an effective reduced order model of the cavity
dynamic system. Directions and methods to further
streamline and simplify the unsteady pressure predictor
have been highlighted
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