May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension

Aims Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide and fewer than half of those with hypertension are aware of it. May Measurement Month (MMM) is a global campaign set up in 2017, to raise awareness of high BP and as a pragmatic solution to a lack of formal screening worldwide. The 2018 campaign was expanded, aiming to include more participants and countries. Methods and results Eighty-nine countries participated in MMM 2018. Volunteers (≥18 years) were recruited through opportunistic sampling at a variety of screening sites. Each participant had three BP measurements and completed a questionnaire on demographic, lifestyle, and environmental factors. Hypertension was defined as a systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, or taking antihypertensive medication. In total, 74.9% of screenees provided three BP readings. Multiple imputation using chained equations was used to impute missing readings. 1 504 963 individuals (mean age 45.3 years; 52.4% female) were screened. After multiple imputation, 502 079 (33.4%) individuals had hypertension, of whom 59.5% were aware of their diagnosis and 55.3% were taking antihypertensive medication. Of those on medication, 60.0% were controlled and of all hypertensives, 33.2% were controlled. We detected 224 285 individuals with untreated hypertension and 111 214 individuals with inadequately treated (systolic BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg) hypertension. Conclusion May Measurement Month expanded significantly compared with 2017, including more participants in more countries. The campaign identified over 335 000 adults with untreated or inadequately treated hypertension. In the absence of systematic screening programmes, MMM was effective at raising awareness at least among these individuals at risk

Steps foward determination of the size and structure of the broad-line region in active galactic nuclei. V. Variability of the ultraviolet continuum and emission lines of NGC 3783

We report on the results of intensive ultraviolet spectral monitoring of the Seyfert 1 galaxy NGC 3783. The nucleus of NGC 3783 was observed with the International Ultraviolet Explorer satellite on a regular basis for a total of 7 months, once every 4 days for the first 172 days and once every other day for the final 50 days. Significant variability was observed in both continuum and emission-line ftuxes. The light curves for the con­ tinuum ftuxes exhibited two well-defined local mínima or "dips," the first lasting <~20 days and the second <~4 days, with additional episodes of relatively rapid ftickering of approximately the same amplitude. As in the case of NGC 5548 (the only other Seyfert galaxy that has been the subject of such an intensive, sustained monitoring effort), the largest continuum variations were seen at the shortest wavelengths, so that the continuum became "harder" when brighter. The variations in the continuum occurred simultaneously at ali wavelengths (Δt < 2 days). Generally, the amplitude of variability of the emission lines was lower than (or comparable to) that of the continuum. Apart from Mg II (which varied little) and N v (which is relatively weak and badly blended with Lyα), the light curves of the emission lines are very similar to the continuum light curves, in each case with a small systematic delay or "lag." As for NGC 5548, the highest ionization lines seem to respond with shorter lags than the lower ionization lines. The lags found for NGC 3783 are consider­ ably shorter than those obtained for NGC 5548, with values of (formally) ~O days for He II +O III], and ~4 days for Lyα and C IV. The data further suggest lags of~4 days for Si IV+ O IV] and 8-30 days for Si III] +C III]. Mg II lagged the 1460 Å continuum by ~9 days, although this result depends on the method of measuring the line flux and may in fact be due to variability of the underlying Fe n lines. Correlation analysis further shows that the power density spectrum contains substantial unresolved power over timescales of <~2 days, and that the character of the continuum variability may change with time

Steps foward determination of the size and structure of the broad-line region in active galactic nuclei. V. Variability of the ultraviolet continuum and emission lines of NGC 3783

We report on the results of intensive ultraviolet spectral monitoring of the Seyfert 1 galaxy NGC 3783. The nucleus of NGC 3783 was observed with the International Ultraviolet Explorer satellite on a regular basis for a total of 7 months, once every 4 days for the first 172 days and once every other day for the final 50 days. Significant variability was observed in both continuum and emission-line ftuxes. The light curves for the con­ tinuum ftuxes exhibited two well-defined local mínima or "dips," the first lasting <~20 days and the second <~4 days, with additional episodes of relatively rapid ftickering of approximately the same amplitude. As in the case of NGC 5548 (the only other Seyfert galaxy that has been the subject of such an intensive, sustained monitoring effort), the largest continuum variations were seen at the shortest wavelengths, so that the continuum became "harder" when brighter. The variations in the continuum occurred simultaneously at ali wavelengths (Δt < 2 days). Generally, the amplitude of variability of the emission lines was lower than (or comparable to) that of the continuum. Apart from Mg II (which varied little) and N v (which is relatively weak and badly blended with Lyα), the light curves of the emission lines are very similar to the continuum light curves, in each case with a small systematic delay or "lag." As for NGC 5548, the highest ionization lines seem to respond with shorter lags than the lower ionization lines. The lags found for NGC 3783 are consider­ ably shorter than those obtained for NGC 5548, with values of (formally) ~O days for He II +O III], and ~4 days for Lyα and C IV. The data further suggest lags of~4 days for Si IV+ O IV] and 8-30 days for Si III] +C III]. Mg II lagged the 1460 Å continuum by ~9 days, although this result depends on the method of measuring the line flux and may in fact be due to variability of the underlying Fe n lines. Correlation analysis further shows that the power density spectrum contains substantial unresolved power over timescales of <~2 days, and that the character of the continuum variability may change with time

Steps toward determination of the size and structure of the broad-line region in active galactic nuclei. VIII. An intensive HST, IUE, and ground-based study of NGC 5548

We present the data and initial results from a combined HST/IUE/ground-based spectroscopic monitoring campaign on the Seyfert I galaxy NGC 5548 that was undertaken in order to address questions that require both higher temporal resolution and higher signal-to-noise ratios than were obtained in our previous multiwavelength monitoring of this galaxy in 1988-1989. IUE spectra were obtained once every 2 days for a period of 74 days beginning on 1993 March 14. During the last 39 days of this campaign, spectroscopic observations were also made with the HST Faint Object Spectrograph (FOS) on a daily basis. Ground-based observations, consisting of 165 optical spectra and 77 photometric observations (both eco imaging and aperture photometry), are reported for the period 1992 October-1993 September, although many of the data are concentrated around the time of the satellite-based program. These data constitute a fifth year of intensive optical monitoring of this galaxy. In this contribution we describe the acquisition and reduction of ali of the satellite and ground-based data obtained in this program. We describe in detail various photometric problems with the FOS and explain how we identified and corrected for various anomalies. During the HST portion of the monitoring campaign, the 1350 Å continuum flux is found to have varied by nearly a factor of 2. In other wave bands, the continuum shows nearly identical behavior, except that the amplitude of variability is larger at shorter wavelengths, and the continuum light curves appear to show more short­ timescale variability at shorter wavelengths. The broad emission lines also vary in flux, with amplitudes that are slightly smaller than the UV continuum variations and with a small time delay relative to the UV continuum. On the basis of simple time-series analysis of the UV and optical continuum and emission-line light curves, we find (1) that the ultraviolet and optical continuum variations are virtually simultaneous, with any lag between the 1350 Å continuum and the 5100 Å continuum amounting to less than about 1 day; (2) that the variations in the highest ionization lines observed, He II λ1640 and N v λ1240, lag behind the continuum variations by somewhat less than 2 days; and (3) that the velocity field of the C IV-emitting region is not dominated by radial motion. The results on the C IV velocity field are pretiminary and quite uncertain, but there are some weak indications that the emission-line wings (|Δv|≥ 3000 km s-ˡ) respond to continuum variations slightly more rapidly than does the core. The optical observations show that the variations in the broad Hβ line flux follow the continuum variations with time lag of around 2 weeks, about twice the lag for Lyα and C IV, as in our previous monitoring campaign on this same galaxy. However, the lags measured for Lyα, C IV, and Hβ are each slightly smaller than previous determmations. We confirm two trends reported eartier, namely, (1) that the UV /optical continuum becomes "harder" as it gets brighter and (2) that the highest ionization emission lines have the shortest lags, thus indicating radial ionization stratification of a broad-line region that spans over an order of magnitude range in radius

Steps toward determination of the size and structure of the broad-line region in active galactic nuclei. VIII. An intensive HST, IUE, and ground-based study of NGC 5548

We present the data and initial results from a combined HST/IUE/ground-based spectroscopic monitoring campaign on the Seyfert I galaxy NGC 5548 that was undertaken in order to address questions that require both higher temporal resolution and higher signal-to-noise ratios than were obtained in our previous multiwavelength monitoring of this galaxy in 1988-1989. IUE spectra were obtained once every 2 days for a period of 74 days beginning on 1993 March 14. During the last 39 days of this campaign, spectroscopic observations were also made with the HST Faint Object Spectrograph (FOS) on a daily basis. Ground-based observations, consisting of 165 optical spectra and 77 photometric observations (both eco imaging and aperture photometry), are reported for the period 1992 October-1993 September, although many of the data are concentrated around the time of the satellite-based program. These data constitute a fifth year of intensive optical monitoring of this galaxy. In this contribution we describe the acquisition and reduction of ali of the satellite and ground-based data obtained in this program. We describe in detail various photometric problems with the FOS and explain how we identified and corrected for various anomalies. During the HST portion of the monitoring campaign, the 1350 Å continuum flux is found to have varied by nearly a factor of 2. In other wave bands, the continuum shows nearly identical behavior, except that the amplitude of variability is larger at shorter wavelengths, and the continuum light curves appear to show more short­ timescale variability at shorter wavelengths. The broad emission lines also vary in flux, with amplitudes that are slightly smaller than the UV continuum variations and with a small time delay relative to the UV continuum. On the basis of simple time-series analysis of the UV and optical continuum and emission-line light curves, we find (1) that the ultraviolet and optical continuum variations are virtually simultaneous, with any lag between the 1350 Å continuum and the 5100 Å continuum amounting to less than about 1 day; (2) that the variations in the highest ionization lines observed, He II λ1640 and N v λ1240, lag behind the continuum variations by somewhat less than 2 days; and (3) that the velocity field of the C IV-emitting region is not dominated by radial motion. The results on the C IV velocity field are pretiminary and quite uncertain, but there are some weak indications that the emission-line wings (|Δv|≥ 3000 km s-ˡ) respond to continuum variations slightly more rapidly than does the core. The optical observations show that the variations in the broad Hβ line flux follow the continuum variations with time lag of around 2 weeks, about twice the lag for Lyα and C IV, as in our previous monitoring campaign on this same galaxy. However, the lags measured for Lyα, C IV, and Hβ are each slightly smaller than previous determmations. We confirm two trends reported eartier, namely, (1) that the UV /optical continuum becomes "harder" as it gets brighter and (2) that the highest ionization emission lines have the shortest lags, thus indicating radial ionization stratification of a broad-line region that spans over an order of magnitude range in radius