The relationship between healthy lifestyle behaviours and outcomes for people living with and beyond cancer: an overview of Systematic Reviews

There are an extensive number of published evidence reviews examining the influence of lifestyle behaviours on cancer outcomes. Healthy lifestyles are a significant topic of debate in oncology and in policy and practice organisations that support people living with and beyond cancer. Such reviews vary in quality, address different relationships, outcomes and cancers, and there is often more than one review on important topics. This makes it difficult for policy and practice professionals to make decisions about the prescription and promotion of lifestyle behaviours for cancer populations. An overview of systematic reviews provides a single, overarching summary of evidence from published systematic reviews and compares and contrasts the findings of systematic reviews, providing healthcare professionals with the evidence needed for more effective decision making (Smith et al. 2011). This overview of systematic reviews synthesises evidence from systematic reviews on smoking, physical activity, dietary behaviours and alcohol consumption to present a summary of evidence about the relationships between these lifestyle behaviours and outcomes for people living with and beyond cancer

Effect of Supplementation on Performance and Faecal Particle Size Distribution for Yearling Horses and Weaned Calves Grazing Coastal Bermudagrass

Supplements are often fed, especially to horses, without realistic expectations of the magnitude of performance response nor knowledge of biological or economic efficiencies of supplementation. The objectives of this experiment were to compare performance of weaned calves vs yearling horses grazing \u27Coastal\u27 bermudagrass [Cynodon dactylon (L.) Pers] (COS) pastures with and without a protein-energy supplement, and to assess faecal particle size distribution for both calves and horses to document digesta dynamics

A systematic overview of reviews of the effectiveness and cost effectiveness of interventions to promote healthy lifestyle behaviours in people living with or beyond cancer

An overview of systematic reviews synthesised evidence on the relationship between smoking, physical activity, dietary behaviours and alcohol consumption and important outcomes for people living with and beyond cancer. That review demonstrated that some lifestyle behaviours may be associated with important outcomes in people living with and beyond cancer (PLWBC). However it did not inform us of whether specifically delivering interventions aimed at modifying lifestyle behaviours effectively improve outcomes for PLWBC. How to promote and sustain healthy lifestyle behaviours in cancer populations is not well understood. A single, overarching summary of evidence from published systematic reviews of lifestyle interventions which compares and contrasts findings can provide policy and practice professionals with the evidence needed for more effective decision making. This overview of systematic reviews provides a synthesis of evidence on the effectiveness and cost-effectiveness of interventions aimed at altering lifestyle behaviours for improving outcomes for people living with and beyond cancer

Comparing the Cognitive Screening Tools: MMSE and SLUMS

Practitioners have long relied upon the Mini Mental Status Exam (MMSE) to quickly assess cognitive functioning in older adults. The Saint Louis University Mental Status (SLUMS) exam possesses many potential psychometric advantages, however data on the relationship between scores on the SLUMS and MMSE has yet to be established. Therefore, the purpose of this study was to establish comparative norms between the MMSE and the SLUMS examinations. The current study hypothesized that participants would score lower on the SLUMS than the MMSE, with adults exhibiting higher levels of cognitive reserve, as measured by educational attainment, having a greater difference between the test scores. A total of 118 individuals (96 female, 21 male) with an age range from 41 to 96 (M=80.03, SD=8.71) with an average educational attainment of 14.97 years (SD= 2.68), completed both tests. Results indicate a significant difference between the mean SLUMS and MMSE scores (p\u3c.001), as well as a significant difference between those in assisted and independent living environments (p\u3c.001). The evidence did not support the cognitive reserve hypothesis. Implications and suggestions for future research will be discussed

Plasma Channels And Laser Pulse Tailoring For Gev Laser-Plasma Accelerators

We have demonstrated distortion-free guiding of I TW pulses at near relativistic intensity (0.2 x 10(18) W/cm(2)) over 60 Rayleigh lengths at 20 Hz repetition rate in a preformed helium plasma channel. As steps toward efficient channeled Laser Wakefield Acceleration up to the dephasing limit, we have upgraded our laser system from I to 4 TW, adapted femtosecond interferometric diagnostics to probe plasma density fluctuations inside the channel, and developed detailed strategies for managing ionization distortions at the channel entrance and exit at the upgraded intensity. We also report simulations, and preliminary experiments, that explore a strategy for Raman-seeding laser pulses to coherently control both unchanneled and channeled LWFA in order to lower the laser energy threshold and increase the repetition rate of election pickup and acceleration.Physic

Competing Ideas of Social Justice and Space: Locating Critiques of Housing Renewal in Theory and in Practice

This article considers the experience of the English government's policy of Housing Market Renewal from the perspective of spatial justice. The paper first proposes an analytical framework that situates competing notions of territorial social justice within a space of complex sociospatial relations. The dialectic of two formulations of social justice is first set up, comparing 'procedural' or deontological forms of justice and the distributional justice of outcomes. Soja's formulation of spatial justice is advanced as an appropriate balance between spatial and socio-historic contexts for the justice question. Drawing on the literature on sociospatial relations, concrete critiques and justifications of HMR are then positioned in terms of the intersection of structuring principles and policy fields. The role of demolition in urban restructuring programmes is used to explore the differential spatialities involved in different justicial perspectives. It is concluded that 'gentrification' critiques of HMR are only partial in their evaluation of justice and lack normative power. Some practical implications for the design of urban restructuring policies are offered

O stars with weak winds: the Galactic case

We study the stellar and wind properties of a sample of Galactic O dwarfs to track the conditions under which weak winds (i.e mass loss rates lower than ~ 1e-8 Msol/yr) appear. The sample is composed of low and high luminosity dwarfs including Vz stars and stars known to display qualitatively weak winds. Atmosphere models including non-LTE treatment, spherical expansion and line blanketing are computed with the code CMFGEN. Both UV and Ha lines are used to derive wind properties while optical H and He lines give the stellar parameters. Mass loss rates of all stars are found to be lower than expected from the hydrodynamical predictions of Vink et al. (2001). For stars with log L/Lsol > 5.2, the reduction is by less than a factor 5 and is mainly due to the inclusion of clumping in the models. For stars with log L/Lsol < 5.2 the reduction can be as high as a factor 100. The inclusion of X-ray emission in models with low density is crucial to derive accurate mass loss rates from UV lines. The modified wind momentum - luminosity relation shows a significant change of slope around this transition luminosity. Terminal velocities of low luminosity stars are also found to be low. The physical reason for such weak winds is still not clear although the finding of weak winds in Galactic stars excludes the role of a reduced metallicity. X-rays, through the change in the ionisation structure they imply, may be at the origin of a reduction of the radiative acceleration, leading to lower mass loss rates. A better understanding of the origin of X-rays is of crucial importance for the study of the physics of weak winds.Comment: 31 pages, 42 figures. A&A accepted. A version of the paper with full resolution figures is available at http://www.mpe.mpg.de/~martins/publications.htm