404 research outputs found
Development and application of a novel cervical index in an epidemiological investigation of tooth wear, recession and dentine hypersensitivity
A novel cervical tooth wear and recession index, the cervical localisation code, and its application in the prevention and management of dentine hypersensitivity
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Can seasonal hydrological forecasts inform local decisions and actions? A decision-making activity
While this paper has a hydrological focus (a glossaryâ is included) the concept of our decision-making activity will be of wider interest and applicable to those involved in all aspects of geoscience communication.
Seasonal hydrological forecasts (SHF) provide insight into the river and groundwater levels that might be expected over the coming months. This is valuable for informing future flood or drought risk and water availability, yet studies investigating how SHF are used for decision-making are limited. Our activity was designed to capture how different water sector users, broadly flood and drought forecasters, water resource managers and groundwater hydrologists, interpret and act on SHF to inform decisions in the West Thames, UK. Using a combination of operational and hypothetical forecasts, participants were provided with 3 sets of progressively confident and locally tailored SHF for a flood event in 3 monthsâ time. Participants played with their âday-jobâ hat on and were not informed whether the SHF represented a flood, drought or business-as-usual scenario. Participants increased their decision/action choice in response to more confident and locally tailored forecasts. Forecasters and groundwater hydrologists were most likely to request further information about the situation, inform other organisations and implement actions for preparedness. Water resource managers more consistently adopted a âwatch and waitâ approach. Local knowledge, risk appetite and experience of previous flood events were important for informing decisions. Discussions highlighted that forecast uncertainty does not necessarily pose a barrier to use, but SHF need to be presented at a finer spatial resolution to aid local decision-making. SHF information that is visualised using combinations of maps, text, hydrographs and tables is beneficial for interpretation and better communication of SHF that are tailored to different user groups is needed. Decision-making activities are a great way of creating realistic scenarios that participants can identify with, whilst allowing the activity creators to observe different thought-processes. In this case, participants stated that the activity complemented their everyday work, introduced them to ongoing scientific developments and enhanced their understanding of how different organisations are engaging with and using SHF to aid decision-making across the West Thames
A prototype system for detecting the radio-frequency pulse associated with cosmic ray air showers
The development of a system to detect the radio-frequency (RF) pulse
associated with extensive air showers of cosmic rays is described. This work
was performed at the CASA/MIA array in Utah, with the intention of designing
equipment that can be used in conjunction with the Auger Giant Array. A small
subset of data (less than 40 out of a total of 600 hours of running time),
taken under low-noise conditions, permitted upper limits to be placed on the
rate for pulses accompanying showers of energies around eV.Comment: 53 pages, LaTeX, 19 figures, published in Nuclear Instruments and
Methods. Revised version; some references update
The Lantern Vol. 22, No. 1, December 1953
⢠Mrs. K. ⢠The Death of Israel Chauncey ⢠The Tramp ⢠The Man Who Remembered the Future ⢠Music, When Soft Voices Die... ⢠Cloud-Horses ⢠Faith ⢠Hymn To What Might Have Been ⢠In Autumn ⢠Reverie ⢠A Lantern ⢠A Taste of Perfection ⢠A Reverie ⢠Small Dog ⢠Rhapsody of Life ⢠From the Tower Window ⢠Ethelred Ihttps://digitalcommons.ursinus.edu/lantern/1061/thumbnail.jp
Where does design thinking leave design? Snapshots of a conversation with the design community
peer-reviewedDesign Thinking has gained recognition as an acclaimed process for generating innovative,
human centred solutions at a social and business level. It has also gained notoriety
amongst many designers, who claim that its success as an exported element of the
design process has resulted in its commodification, and led to it becoming a diluted series
of processes that lack criticality. This article describes the findings from a conversation
session held at DRS2018 which posed the question: Have we reached peak design thinking?
Participants were asked to identify with a range of positions on the topic and were then
given three questions to provide a constructive debate. The findings point to a lack of a
clear distinction between design and Design Thinking, a lack of consensus as to whether a
designer is required in the process and also a lack of agreement as to its benefits. In order
to prevent a continued backlash against Design Thinking, the findings point to the need for
a framework that can outline the clear distinction between design and Design Thinking,
whether the designers skills are required and the context and scale of a project that would
require design or Design Thinking or both
Spitzer observations of Abell 1763 - II: Constraining the nature of activity in the cluster-feeding filament with VLA and XMM-Newton data
The Abell 1763 superstructure at z=0.23 contains the first galaxy filament to
be directly detected using mid-infrared observations. Our previous work has
shown that the frequency of starbursting galaxies, as characterized by 24{\mu}m
emission is much higher within the filament than at either the center of the
rich galaxy cluster, or the field surrounding the system. New VLA and
XMM-Newton data are presented here. We use the radio and X-ray data to examine
the fraction and location of active galaxies, both active galactic nuclei (AGN)
and starbursts. The radio far-infrared correlation, X-ray point source
location, IRAC colors, and quasar positions are all used to gain an
understanding of the presence of dominant AGN. We find very few MIPS-selected
galaxies that are clearly dominated by AGN activity. Most radio selected
members within the filament are starbursts. Within the supercluster, 3 of 8
spectroscopic members detected both in the radio and in the mid-infrared are
radio-bright AGN. They are found at or near the core of Abell 1763. The five
starbursts are located further along the filament. We calculate the physical
properties of the known wide angle tail (WAT) source which is the brightest
cluster galaxy (BCG) of Abell 1763. A second double lobe source is found along
the filament well outside of the virial radius of either cluster. The velocity
offset of the WAT from the X-ray centroid, and the bend of the WAT in the
intracluster medium (ICM) are both consistent with ram pressure stripping,
indicative of streaming motions along the direction of the filament. We
consider this as further evidence of the cluster-feeding nature of the galaxy
filament.Comment: 26 pages, 13 figures AJ, accepte
NOX Enzymes and Pulmonary Disease
Abstract The primary function of the lung is to facilitate the transfer of molecular oxygen (O2; dioxygen) from the atmosphere to the systemic circulation. In addition to its essential role in aerobic metabolism, O2 serves as the physiologic terminal acceptor of electron transfer catalyzed by the NADPH oxidase (NOX) family of oxidoreductases. The evolution of the lungs and circulatory systems in vertebrates was accompanied by increasing diversification of NOX family enzymes, suggesting adaptive roles for NOX-derived reactive oxygen species in normal physiology. However, this adaptation may paradoxically carry detrimental consequences in the setting of overwhelming/persistent environmental stressors, both infectious and noninfectious, and during the process of aging. Here, we review current understanding of NOX enzymes in normal lung physiology and their pathophysiologic roles in a number of pulmonary diseases, including lung infections, acute lung injury, pulmonary arterial hypertension, obstructive lung disorders, fibrotic lung disease, and lung cancer. Antioxid. Redox Signal. 11, 2505-2516.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/78108/1/ars.2009.2599.pd
The Iowa Homemaker vol.16, no.8
Billy Eats, Sleeps and Plays by Barbara Fischer, page 2
Foods for Gods from the Buffet by Helen Miller, page 3
Swing Into Spring! by Beth Johnson, page 4
Color Passports to Spring by Gaynold Carroll, page 5
Teachers Reveal Pets and Peeves by Peggy Schenk, page 6
Awearinâ the Green by Mildred Gauley, page 7
Table Shamrocks by Doris Ingle, page 7
Whatâs New in Home Economics, page 8
News in the Mail from Graduates by Faithe Danielson, page 10
Glad-irons Replace Sad-irons by Ida Ruth Younkin, page 11
Children Around the World by Mae Louise Buchanan, page 11
Behind Bright Jackets, page 12
Hopes in a Chest by Gwen Griffith, page 13
Spring Inventory by Gay Starrak, page 14
French Cookery Puzzles by Beth Cummings, page 16
Wear Polished Nails by Jane Helser, page 1
Recovery from Covid-19 critical illness:a secondary analysis of the ISARIC4C CCP-UK cohort study and the RECOVER trial
Background: We aimed to compare the prevalence and severity of fatigue in survivors of Covid-19 versus non-Covid-19 critical illness, and to explore potential associations between baseline characteristics and worse recovery.
Methods: We conducted a secondary analysis of two prospectively collected datasets. The population included was 92 patients who received invasive mechanical ventilation (IMV) with Covid-19, and 240 patients who received IMV with non-Covid-19 illness before the pandemic. Follow-up data was collected post-hospital discharge using self-reported questionnaires. The main outcome measures were self-reported fatigue severity and the prevalence of severe fatigue (severity >7/10) 3 to 12-months post-hospital discharge.
Results: Covid-19 IMV-patients were significantly younger with less prior comorbidity, and more males, than pre-pandemic IMV-patients. At 3-months, the prevalence (38.9% [7/18] vs. 27.1% [51/188]) and severity (median 5.5/10 vs. 5.0/10) of fatigue was similar between the Covid-19 and pre-pandemic populations respectively. At 6-months, the prevalence (10.3% [3/29] vs. 32.5% [54/166]) and severity (median 2.0/10 vs. 5.7/10) of fatigue was less in the Covid-19 cohort. In the total sample of IMV-patients included (i.e. all Covid-19 and pre- pandemic patients), having Covid-19 was significantly associated with less severe fatigue (severity <7/10) after adjusting for age, sex, and prior comorbidity (adjusted OR 0.35 (95%CI 0.15-0.76, p=0.01).
Conclusion: Fatigue may be less severe after Covid-19 than after other critical illness
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