2,753 research outputs found
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Special Forum on the Philosophy of Teaching Education as Communication: The Pragmatist Tradition
We take the basic course in communication to be a site where associated living is experienced, and where individuals practice the democratic art of referencing and articulating their own behaviors and beliefs to those of others. This democratic practice is associated living is, as American pragmatist and educational philosopher John Dewey insisted, communication itself -- conjoint communicated experience. In this essay, we provide an overview of this pragmatist educational metaphysic and discuss a few consequences of metaphysical beliefs about education
A tale of two regulators: telecom policy participation in Canada
What are the challenges to effective academic participation in telecommunications policymaking? In this article, the authors analyze their experiences with the Canadian Radio-television and Telecommunications Commission and Industry Canada as examples. Their goal is to increase academic policy engagement despite negligible government support for public interest advocacy, as traditional public interest values are discarded by regulators because new technologies are framed as individual rather than collective. Industry Canada is deemed opaque with an “advocacy deficit,” though the CRTC is more transparent and inviting. To succeed in both venues, academics need to work with advocacy organizations as “circumstantial activists.” Such academic participation can offer new conceptual frameworks, add nuance to discourse, substantiate the use of scholarly research in policy debates, and add to policy theory building
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Fast and slow components of the extratropical atmospheric circulation response to CO2 forcing
Poleward shifts of the extratropical atmospheric circulation are a common response to CO2 forcing in global climate models (GCMs), but little is known about the time dependence of this response. Here it is shown that in coupled climate models, the long-term evolution of sea surface temperatures (SSTs) induces two distinct time scales of circulation response to step-like CO2 forcing. In most Coupled Model Intercomparison Project phase 5 GCMs as well as in the multi-model mean, all of the poleward shift of the midlatitude jets and Hadley cell edge occurs in a fast response within 5 to 10 years of the forcing, during which less than half of the expected equilibrium warming is realized. Compared with this fast response, the slow response over subsequent decades to centuries features stronger polar amplification (especially in the Antarctic), enhanced warming in the Southern Ocean, an El Nino-like pattern of tropical Pacific warming, and weaker land-sea contrast. Atmosphere-only GCM experiments demonstrate that the SST evolution drives the difference between the fast and slow circulation responses, although the direct radiative effect of CO2 also contributes to the fast response. It is further shown that the fast and slow responses determine the long-term evolution of the circulation response to warming in the RCP4.5 scenario. The results imply that shifts in midlatitude circulation generally scale with the radiative forcing, rather than with global-mean temperature change. A corollary is that time slices taken from a transient simulation at a given level of warming will considerably overestimate the extratropical circulation response in a stabilized climate
CydDC-mediated reductant export in Escherichia coli controls the transcriptional wiring of energy metabolism and combats nitrosative stress
The glutathione/cysteine exporter CydDC maintains redox balance in Escherichia coli. A cydD mutant strain was used to probe the influence of CydDC upon reduced thiol export, gene expression, metabolic perturbations, intracellular pH homeostasis, and tolerance to nitric oxide (NO). Loss of CydDC was found to decrease extracytoplasmic thiol levels, whereas overexpression diminished the cytoplasmic thiol content. Transcriptomic analysis revealed a dramatic up-regulation of protein chaperones, protein degradation (via phenylpropionate/phenylacetate catabolism), ?-oxidation of fatty acids, and genes involved in nitrate/nitrite reduction. 1H NMR metabolomics revealed elevated methionine and betaine and diminished acetate and NAD+ in cydD cells, which was consistent with the transcriptomics-based metabolic model. The growth rate and ?pH, however, were unaffected, although the cydD strain did exhibit sensitivity to the NO-releasing compound NOC-12. These observations are consistent with the hypothesis that the loss of CydDC-mediated reductant export promotes protein misfolding, adaptations to energy metabolism, and sensitivity to NO. The addition of both glutathione and cysteine to the medium was found to complement the loss of bd -type cytochrome synthesis in a cydD strain (a key component of the pleiotropic cydDC phenotype), providing the first direct evidence that CydDC substrates are able to restore the correct assembly of this respiratory oxidase. These data provide an insight into the metabolic flexibility of E. coli , highlight the importance of bacterial redox homeostasis during nitrosative stress, and report for the first time the ability of periplasmic low molecular weight thiols to restore haem incorporation into a cytochrome complex
The influences of volunteering and paid employment on older New Zealanders health related quality of life while testing for potential confounding variables
Utilizing the QHOQOL-BREF, which ascertains health related quality of life (HRQOL) across four domains, physical, psychology, social and environment, the effects of volunteering and paid employment on the HRQOL of older New Zealanders was assessed while testing four potential confounding variables, age, gender, income and extent of religious belief. About 65% of participants were involved in volunteer activity with about 13% involved in paid employment. Volunteer activity was associated with significantly enhanced HRQOL for three domains, physical, psychology and environment above and beyond the effects of potentially confounding variables. No significant HRQOL effects were revealed with respect to paid employment
Clinical identification of feeding and swallowing disorders in 0-6 month old infants with Down syndrome
Feeding and swallowing disorders have been described in children with a variety of neurodevelopmental disabilities, including Down syndrome (DS). Abnormal feeding and swallowing can be associated with serious sequelae such as failure to thrive and respiratory complications, including aspiration pneumonia. Incidence of dysphagia in young infants with DS has not previously been reported. To assess the identification and incidence of feeding and swallowing problems in young infants with DS, a retrospective chart review of 174 infants, ages 0-6 months was conducted at a single specialty clinic. Fifty-seven percent (100/174) of infants had clinical concerns for feeding and swallowing disorders that warranted referral for Videofluroscopic Swallow Study (VFSS); 96/174 (55%) had some degree of oral and/or pharyngeal phase dysphagia and 69/174 (39%) had dysphagia severe enough to warrant recommendation for alteration of breast milk/formula consistency or nonoral feeds. Infants with certain comorbidities had significant risk for significant dysphagia, including those with functional airway/respiratory abnormalities (OR = 7.2). Infants with desaturation with feeds were at dramatically increased risk (OR = 15.8). All young infants with DS should be screened clinically for feeding and swallowing concerns. If concerns are identified, consideration should be given to further evaluation with VFSS for identification of dysphagia and additional feeding modifications
Rotation of the cluster of galaxies A2107
We present indications of rotation in the galaxy cluster A2107 by a method
that searches for the maximum gradient in the velocity field in a flat
disk-like model of a cluster. Galaxies from cumulative sub-samples containing
more and more distant members from the cluster centre, are projected onto an
axis passing through the centre and we apply a linear regression model on the
projected distances and the line-of-sight velocities . The axis with the
maximum linear correlation coefficient defines the
direction of the maximum velocity gradient, and consequently it presents the
major axis of the apparently elliptical cluster. Because the effects of
rotation are subtle, we put strong emphasis on the estimation of the
uncertainties of the results by implementing different bootstrap techniques. We
have found the rotational effects are more strongly expressed from distances
Mpc from the cluster centre. The total virial mass of the
cluster is (3.2\pm0.6)\times10^{14} {\cal M}_{\sun}, while the virial mass,
corrected for the rotation, is (2.8\pm0.5) \times 10^{14}{\cal M}_{\sun}.Comment: 7 pages, 9 figures gzipped tar file. to be published in MNRA
Educating Advanced Practice Nurses in Using Social Media in Rural Health Care
Health care in the United States is facing a crisis in providing access to quality care for those in underserved and rural regions. Advanced practice nurses are at the forefront of addressing such issues, through modalities such as health care technology. Many nursing education programs are seeking strategies for better educating students on technology utilization. Health care technology includes electronic health records, telemedicine, and clinical decision support systems. However, little focus has been placed on the role of social media in health care. This paper describes an educational workshop using standardized patients and hands-on experiences to introduce advanced practice nurses in a Doctor of Nursing Practice program to the role of social media in addressing issues inherent in the delivery of rural health care. The students explore innovative approaches for utilizing social media for patient and caregiver support as well as identify online resources that assist providers in a rural setting
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